ATE111912T1 - Xanthinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische präparate. - Google Patents

Xanthinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische präparate.

Info

Publication number
ATE111912T1
ATE111912T1 AT89311779T AT89311779T ATE111912T1 AT E111912 T1 ATE111912 T1 AT E111912T1 AT 89311779 T AT89311779 T AT 89311779T AT 89311779 T AT89311779 T AT 89311779T AT E111912 T1 ATE111912 T1 AT E111912T1
Authority
AT
Austria
Prior art keywords
substituted
compound
xanthind
derivatives
production
Prior art date
Application number
AT89311779T
Other languages
English (en)
Inventor
Harald Beecham-Wuelfi Maschler
Rolf Theodor Beecham-Wue Wilke
Johannes Beecham-Wuelfin Jukna
Original Assignee
Smithkline Beecham Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Pharma Gmbh filed Critical Smithkline Beecham Pharma Gmbh
Application granted granted Critical
Publication of ATE111912T1 publication Critical patent/ATE111912T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
AT89311779T 1988-11-14 1989-11-14 Xanthinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische präparate. ATE111912T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888826595A GB8826595D0 (en) 1988-11-14 1988-11-14 Active compounds

Publications (1)

Publication Number Publication Date
ATE111912T1 true ATE111912T1 (de) 1994-10-15

Family

ID=10646826

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89311779T ATE111912T1 (de) 1988-11-14 1989-11-14 Xanthinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische präparate.

Country Status (15)

Country Link
EP (1) EP0369744B1 (de)
JP (1) JPH02178283A (de)
KR (1) KR0161261B1 (de)
AT (1) ATE111912T1 (de)
AU (1) AU614680B2 (de)
CA (1) CA2002834C (de)
DE (1) DE68918406T2 (de)
DK (1) DK570689A (de)
ES (1) ES2064461T3 (de)
GB (1) GB8826595D0 (de)
HK (1) HK1004551A1 (de)
IE (1) IE65585B1 (de)
NZ (1) NZ231380A (de)
PT (1) PT92303B (de)
ZA (1) ZA898678B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8918297D0 (en) * 1989-08-10 1989-09-20 Beecham Group Plc Novel treatment
GB8929208D0 (en) * 1989-12-27 1990-02-28 Almirall Lab New xanthine derivatives
JPH04112889A (ja) * 1990-09-04 1992-04-14 Kyowa Hakko Kogyo Co Ltd Ｋｓ―５０５誘導体
GB9020959D0 (en) * 1990-09-26 1990-11-07 Beecham Group Plc Novel compounds
US5342841A (en) * 1992-03-12 1994-08-30 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives
GB9312853D0 (en) 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
CA2206287C (en) * 1994-12-13 2001-03-20 Mark Chasin Aryl thioxanthines
CA2206804C (en) 1994-12-13 2002-03-19 Euro-Celtique, S.A. Trisubstituted thioxanthines
JPH11505241A (ja) * 1995-05-19 1999-05-18 カイロサイエンス・リミテッド キサンチン類およびこれらの治療的使用
US6166041A (en) 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
PT812844E (pt) * 1996-06-07 2003-03-31 Hoechst Ag Utilizacao de derivados de teofilina para o tratamento e profilaxia de estados de choque novos compostos de xantina e processo para a sua preparacao
US5965555A (en) * 1996-06-07 1999-10-12 Hoechst Aktiengesellschaft Xanthine compounds having terminally animated alkynol side chains
GB9623859D0 (en) * 1996-11-15 1997-01-08 Chiroscience Ltd Novel compounds
GB9703044D0 (en) 1997-02-14 1997-04-02 Glaxo Group Ltd Phenyl xanthine esters and amides
GB9817623D0 (en) 1998-08-13 1998-10-07 Glaxo Group Ltd Pharmaceutical compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608236A5 (de) * 1974-01-22 1978-12-29 Wuelfing J A Fa
US4061753A (en) * 1976-02-06 1977-12-06 Interx Research Corporation Treating psoriasis with transient pro-drug forms of xanthine derivatives
CA1077932A (en) * 1976-03-31 1980-05-20 Berlex Laboratories, Inc. Xanthine compounds and method of treating bronchospastic and allergic diseases
DE2714953C2 (de) * 1977-04-02 1986-09-25 Hoechst Ag, 6230 Frankfurt Arzneimittel
SE416810C (sv) * 1977-10-14 1982-05-11 Draco Ab Forfarande for framstellning av xantinderivat med antiallergisk aktivitet
SE7810947L (sv) * 1978-10-20 1980-04-21 Draco Ab 3-alkylxanthines
CH643260A5 (fr) * 1980-05-02 1984-05-30 Nestle Sa 1-allyl-3-butyl-8-methylxanthine, procede de preparation et utilisation dans un medicament.
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung

Also Published As

Publication number Publication date
AU614680B2 (en) 1991-09-05
DK570689A (da) 1990-05-15
EP0369744A3 (de) 1991-04-10
IE65585B1 (en) 1995-11-01
NZ231380A (en) 1992-12-23
JPH02178283A (ja) 1990-07-11
ZA898678B (en) 1990-09-26
EP0369744B1 (de) 1994-09-21
KR900007842A (ko) 1990-06-02
DK570689D0 (da) 1989-11-14
PT92303B (pt) 1995-07-18
CA2002834C (en) 2000-02-22
KR0161261B1 (ko) 1998-12-01
AU4466789A (en) 1990-05-17
PT92303A (pt) 1990-05-31
DE68918406T2 (de) 1995-03-30
ES2064461T3 (es) 1995-02-01
GB8826595D0 (en) 1988-12-21
EP0369744A2 (de) 1990-05-23
HK1004551A1 (en) 1998-11-27
DE68918406D1 (de) 1994-10-27
CA2002834A1 (en) 1990-05-14
IE893653L (en) 1990-05-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee