HK1004551A1 - Xanthine derivatives process for their preparation and pharmaceutical compositions - Google Patents
Xanthine derivatives process for their preparation and pharmaceutical compositionsInfo
- Publication number
- HK1004551A1 HK1004551A1 HK98103675A HK98103675A HK1004551A1 HK 1004551 A1 HK1004551 A1 HK 1004551A1 HK 98103675 A HK98103675 A HK 98103675A HK 98103675 A HK98103675 A HK 98103675A HK 1004551 A1 HK1004551 A1 HK 1004551A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- substituted
- compound
- preparation
- pharmaceutical compositions
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888826595A GB8826595D0 (en) | 1988-11-14 | 1988-11-14 | Active compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1004551A1 true HK1004551A1 (en) | 1998-11-27 |
Family
ID=10646826
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK98103675A HK1004551A1 (en) | 1988-11-14 | 1998-04-29 | Xanthine derivatives process for their preparation and pharmaceutical compositions |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0369744B1 (xx) |
JP (1) | JPH02178283A (xx) |
KR (1) | KR0161261B1 (xx) |
AT (1) | ATE111912T1 (xx) |
AU (1) | AU614680B2 (xx) |
CA (1) | CA2002834C (xx) |
DE (1) | DE68918406T2 (xx) |
DK (1) | DK570689A (xx) |
ES (1) | ES2064461T3 (xx) |
GB (1) | GB8826595D0 (xx) |
HK (1) | HK1004551A1 (xx) |
IE (1) | IE65585B1 (xx) |
NZ (1) | NZ231380A (xx) |
PT (1) | PT92303B (xx) |
ZA (1) | ZA898678B (xx) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8918297D0 (en) * | 1989-08-10 | 1989-09-20 | Beecham Group Plc | Novel treatment |
GB8929208D0 (en) * | 1989-12-27 | 1990-02-28 | Almirall Lab | New xanthine derivatives |
JPH04112889A (ja) * | 1990-09-04 | 1992-04-14 | Kyowa Hakko Kogyo Co Ltd | Ks―505誘導体 |
GB9020959D0 (en) * | 1990-09-26 | 1990-11-07 | Beecham Group Plc | Novel compounds |
US5342841A (en) * | 1992-03-12 | 1994-08-30 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives |
GB9312853D0 (en) | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
US5591776A (en) | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
US5922751A (en) | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
ATE247655T1 (de) | 1994-12-13 | 2003-09-15 | Euro Celtique Sa | Dreifachsubstituierte thioxanthine |
WO1996018399A1 (en) * | 1994-12-13 | 1996-06-20 | Euro-Celtique, S.A. | Aryl thioxanthines |
CA2218548A1 (en) * | 1995-05-19 | 1996-11-21 | Chiroscience Limited | Xanthines and their therapeutic use |
US6166041A (en) | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
US6075016A (en) | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
US5864037A (en) | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
DK0812844T3 (da) * | 1996-06-07 | 2003-02-17 | Hoechst Ag | Anvendelse af theophyllinderivater til behandling og profylakse af choktilstande, nye xanthinforbindelser og fremgangsmåder til deres fremstilling |
US5965555A (en) * | 1996-06-07 | 1999-10-12 | Hoechst Aktiengesellschaft | Xanthine compounds having terminally animated alkynol side chains |
GB9623859D0 (en) * | 1996-11-15 | 1997-01-08 | Chiroscience Ltd | Novel compounds |
GB9703044D0 (en) | 1997-02-14 | 1997-04-02 | Glaxo Group Ltd | Phenyl xanthine esters and amides |
GB9817623D0 (en) | 1998-08-13 | 1998-10-07 | Glaxo Group Ltd | Pharmaceutical compounds |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH608236A5 (xx) * | 1974-01-22 | 1978-12-29 | Wuelfing J A Fa | |
US4061753A (en) * | 1976-02-06 | 1977-12-06 | Interx Research Corporation | Treating psoriasis with transient pro-drug forms of xanthine derivatives |
CA1077932A (en) * | 1976-03-31 | 1980-05-20 | Berlex Laboratories, Inc. | Xanthine compounds and method of treating bronchospastic and allergic diseases |
DE2714953C2 (de) * | 1977-04-02 | 1986-09-25 | Hoechst Ag, 6230 Frankfurt | Arzneimittel |
SE416810C (sv) * | 1977-10-14 | 1982-07-19 | Draco Ab | Forfarande for framstellning av xantinderivat med antiallergisk aktivitet |
SE7810947L (sv) * | 1978-10-20 | 1980-04-21 | Draco Ab | 3-alkylxanthines |
CH643260A5 (fr) * | 1980-05-02 | 1984-05-30 | Nestle Sa | 1-allyl-3-butyl-8-methylxanthine, procede de preparation et utilisation dans un medicament. |
DE3525801A1 (de) * | 1985-07-19 | 1987-01-22 | Hoechst Ag | Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung |
-
1988
- 1988-11-14 GB GB888826595A patent/GB8826595D0/en active Pending
-
1989
- 1989-11-14 EP EP89311779A patent/EP0369744B1/en not_active Expired - Lifetime
- 1989-11-14 JP JP1296018A patent/JPH02178283A/ja active Pending
- 1989-11-14 CA CA002002834A patent/CA2002834C/en not_active Expired - Fee Related
- 1989-11-14 ZA ZA898678A patent/ZA898678B/xx unknown
- 1989-11-14 PT PT92303A patent/PT92303B/pt not_active IP Right Cessation
- 1989-11-14 NZ NZ231380A patent/NZ231380A/xx unknown
- 1989-11-14 IE IE365389A patent/IE65585B1/en not_active IP Right Cessation
- 1989-11-14 AU AU44667/89A patent/AU614680B2/en not_active Ceased
- 1989-11-14 DE DE68918406T patent/DE68918406T2/de not_active Expired - Fee Related
- 1989-11-14 KR KR1019890016637A patent/KR0161261B1/ko not_active IP Right Cessation
- 1989-11-14 ES ES89311779T patent/ES2064461T3/es not_active Expired - Lifetime
- 1989-11-14 AT AT89311779T patent/ATE111912T1/de not_active IP Right Cessation
- 1989-11-14 DK DK570689A patent/DK570689A/da not_active Application Discontinuation
-
1998
- 1998-04-29 HK HK98103675A patent/HK1004551A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2002834C (en) | 2000-02-22 |
JPH02178283A (ja) | 1990-07-11 |
NZ231380A (en) | 1992-12-23 |
DE68918406D1 (de) | 1994-10-27 |
ATE111912T1 (de) | 1994-10-15 |
DK570689D0 (da) | 1989-11-14 |
DK570689A (da) | 1990-05-15 |
KR0161261B1 (ko) | 1998-12-01 |
DE68918406T2 (de) | 1995-03-30 |
IE893653L (en) | 1990-05-14 |
ES2064461T3 (es) | 1995-02-01 |
GB8826595D0 (en) | 1988-12-21 |
KR900007842A (ko) | 1990-06-02 |
AU614680B2 (en) | 1991-09-05 |
IE65585B1 (en) | 1995-11-01 |
AU4466789A (en) | 1990-05-17 |
PT92303A (pt) | 1990-05-31 |
CA2002834A1 (en) | 1990-05-14 |
ZA898678B (en) | 1990-09-26 |
EP0369744B1 (en) | 1994-09-21 |
EP0369744A3 (en) | 1991-04-10 |
EP0369744A2 (en) | 1990-05-23 |
PT92303B (pt) | 1995-07-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20061114 |