HK1004551A1 - Xanthine derivatives process for their preparation and pharmaceutical compositions - Google Patents

Xanthine derivatives process for their preparation and pharmaceutical compositions

Info

Publication number
HK1004551A1
HK1004551A1 HK98103675A HK98103675A HK1004551A1 HK 1004551 A1 HK1004551 A1 HK 1004551A1 HK 98103675 A HK98103675 A HK 98103675A HK 98103675 A HK98103675 A HK 98103675A HK 1004551 A1 HK1004551 A1 HK 1004551A1
Authority
HK
Hong Kong
Prior art keywords
substituted
compound
preparation
pharmaceutical compositions
formula
Prior art date
Application number
HK98103675A
Other languages
English (en)
Inventor
Harald Maschler
Rolf Theodor Wilke
Johannes Jukna
Original Assignee
Smithkline Beecham Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Pharma Gmbh filed Critical Smithkline Beecham Pharma Gmbh
Publication of HK1004551A1 publication Critical patent/HK1004551A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
HK98103675A 1988-11-14 1998-04-29 Xanthine derivatives process for their preparation and pharmaceutical compositions HK1004551A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888826595A GB8826595D0 (en) 1988-11-14 1988-11-14 Active compounds

Publications (1)

Publication Number Publication Date
HK1004551A1 true HK1004551A1 (en) 1998-11-27

Family

ID=10646826

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98103675A HK1004551A1 (en) 1988-11-14 1998-04-29 Xanthine derivatives process for their preparation and pharmaceutical compositions

Country Status (15)

Country Link
EP (1) EP0369744B1 (xx)
JP (1) JPH02178283A (xx)
KR (1) KR0161261B1 (xx)
AT (1) ATE111912T1 (xx)
AU (1) AU614680B2 (xx)
CA (1) CA2002834C (xx)
DE (1) DE68918406T2 (xx)
DK (1) DK570689A (xx)
ES (1) ES2064461T3 (xx)
GB (1) GB8826595D0 (xx)
HK (1) HK1004551A1 (xx)
IE (1) IE65585B1 (xx)
NZ (1) NZ231380A (xx)
PT (1) PT92303B (xx)
ZA (1) ZA898678B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8918297D0 (en) * 1989-08-10 1989-09-20 Beecham Group Plc Novel treatment
GB8929208D0 (en) * 1989-12-27 1990-02-28 Almirall Lab New xanthine derivatives
JPH04112889A (ja) * 1990-09-04 1992-04-14 Kyowa Hakko Kogyo Co Ltd Ｋｓ―５０５誘導体
GB9020959D0 (en) * 1990-09-26 1990-11-07 Beecham Group Plc Novel compounds
US5342841A (en) * 1992-03-12 1994-08-30 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives
GB9312853D0 (en) 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
ATE247655T1 (de) 1994-12-13 2003-09-15 Euro Celtique Sa Dreifachsubstituierte thioxanthine
WO1996018399A1 (en) * 1994-12-13 1996-06-20 Euro-Celtique, S.A. Aryl thioxanthines
CA2218548A1 (en) * 1995-05-19 1996-11-21 Chiroscience Limited Xanthines and their therapeutic use
US6166041A (en) 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
DK0812844T3 (da) * 1996-06-07 2003-02-17 Hoechst Ag Anvendelse af theophyllinderivater til behandling og profylakse af choktilstande, nye xanthinforbindelser og fremgangsmåder til deres fremstilling
US5965555A (en) * 1996-06-07 1999-10-12 Hoechst Aktiengesellschaft Xanthine compounds having terminally animated alkynol side chains
GB9623859D0 (en) * 1996-11-15 1997-01-08 Chiroscience Ltd Novel compounds
GB9703044D0 (en) 1997-02-14 1997-04-02 Glaxo Group Ltd Phenyl xanthine esters and amides
GB9817623D0 (en) 1998-08-13 1998-10-07 Glaxo Group Ltd Pharmaceutical compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608236A5 (xx) * 1974-01-22 1978-12-29 Wuelfing J A Fa
US4061753A (en) * 1976-02-06 1977-12-06 Interx Research Corporation Treating psoriasis with transient pro-drug forms of xanthine derivatives
CA1077932A (en) * 1976-03-31 1980-05-20 Berlex Laboratories, Inc. Xanthine compounds and method of treating bronchospastic and allergic diseases
DE2714953C2 (de) * 1977-04-02 1986-09-25 Hoechst Ag, 6230 Frankfurt Arzneimittel
SE416810C (sv) * 1977-10-14 1982-07-19 Draco Ab Forfarande for framstellning av xantinderivat med antiallergisk aktivitet
SE7810947L (sv) * 1978-10-20 1980-04-21 Draco Ab 3-alkylxanthines
CH643260A5 (fr) * 1980-05-02 1984-05-30 Nestle Sa 1-allyl-3-butyl-8-methylxanthine, procede de preparation et utilisation dans un medicament.
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung

Also Published As

Publication number Publication date
CA2002834C (en) 2000-02-22
JPH02178283A (ja) 1990-07-11
NZ231380A (en) 1992-12-23
DE68918406D1 (de) 1994-10-27
ATE111912T1 (de) 1994-10-15
DK570689D0 (da) 1989-11-14
DK570689A (da) 1990-05-15
KR0161261B1 (ko) 1998-12-01
DE68918406T2 (de) 1995-03-30
IE893653L (en) 1990-05-14
ES2064461T3 (es) 1995-02-01
GB8826595D0 (en) 1988-12-21
KR900007842A (ko) 1990-06-02
AU614680B2 (en) 1991-09-05
IE65585B1 (en) 1995-11-01
AU4466789A (en) 1990-05-17
PT92303A (pt) 1990-05-31
CA2002834A1 (en) 1990-05-14
ZA898678B (en) 1990-09-26
EP0369744B1 (en) 1994-09-21
EP0369744A3 (en) 1991-04-10
EP0369744A2 (en) 1990-05-23
PT92303B (pt) 1995-07-18

Similar Documents

Publication Publication Date Title
HK1004551A1 (en) Xanthine derivatives process for their preparation and pharmaceutical compositions
DE10199003I2 (xx)
EP0389282A3 (en) Xanthinederivatives, process for their preparation and their pharmaceutical use
AU6128590A (en) Novel compounds
AU6129890A (en) Novel compounds
HUT52764A (en) Process for producing pyrimidindione derivatives and pharmaceutical compositions containing them as active components
HUT53368A (en) Process for producing pyrazolo-pyridine derivatives and pharmaceutical compositions containing them
ES8605806A1 (es) Procedimiento de preparacion de nuevos derivados de la xan- tina y de sus sales de adicion con acidos apropiados
HU904785D0 (en) Process for the production of medicaments
IL102093A0 (en) 1-methylcarbapenem derivatives,processes for the preparation thereof,and pharmaceutical compositions containing the same
IL77452A0 (en) Derivatives of arylcyclobutylalkylamines,their preparation and pharmaceutical compositions containing them
GR3020682T3 (en) Use of dioxabicyclo [3.3.0]octane derivatives for the manufacture of a medicament for inhibiting the metabolism of cholesterol.
HUT54362A (en) Process for producing cumarin derivatives and pharmaceutical compositions containing them
DE68922053D1 (de) Pyridoindolderivate und Verfahren zu ihrer Herstellung.
DE3564106D1 (en) 4-phenylaminopyridine derivatives, process of the preparation thereof and pharmaceutical compositions containing them
EP0420086A3 (en) Pyrimidoindole derivatives and processes for preparation thereof
HUT68636A (en) Benzopyrane derivatives, process for producing them, and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20061114