ATE110064T1 - Azacyclische carbonsäurederivate,ihre herstellung und verwendung. - Google Patents

Azacyclische carbonsäurederivate,ihre herstellung und verwendung.

Info

Publication number
ATE110064T1
ATE110064T1 AT89108850T AT89108850T ATE110064T1 AT E110064 T1 ATE110064 T1 AT E110064T1 AT 89108850 T AT89108850 T AT 89108850T AT 89108850 T AT89108850 T AT 89108850T AT E110064 T1 ATE110064 T1 AT E110064T1
Authority
AT
Austria
Prior art keywords
azacyclic
production
acid derivatives
carbon acid
substituted ring
Prior art date
Application number
AT89108850T
Other languages
English (en)
Inventor
Lars Jacob Stray Knutsen
Knud Erik Andersen
Anker Steen Jorgensen
Ursula Sonnewald
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE110064T1 publication Critical patent/ATE110064T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Luminescent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
AT89108850T 1988-05-18 1989-05-17 Azacyclische carbonsäurederivate,ihre herstellung und verwendung. ATE110064T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK270488A DK270488D0 (da) 1988-05-18 1988-05-18 Hidtil ukendte o-substituerede ketoximer

Publications (1)

Publication Number Publication Date
ATE110064T1 true ATE110064T1 (de) 1994-09-15

Family

ID=8114842

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89108850T ATE110064T1 (de) 1988-05-18 1989-05-17 Azacyclische carbonsäurederivate,ihre herstellung und verwendung.

Country Status (18)

Country Link
US (1) US5039685A (de)
EP (1) EP0342635B1 (de)
JP (1) JP2824661B2 (de)
KR (1) KR900018058A (de)
AT (1) ATE110064T1 (de)
AU (1) AU622178B2 (de)
CA (1) CA1337123C (de)
DE (1) DE68917517T2 (de)
DK (1) DK270488D0 (de)
ES (1) ES2058383T3 (de)
FI (1) FI93955C (de)
IE (1) IE66016B1 (de)
IL (1) IL90313A0 (de)
NO (1) NO177262C (de)
NZ (1) NZ229136A (de)
PH (1) PH26373A (de)
PT (1) PT90607B (de)
ZA (1) ZA893733B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK704488D0 (da) * 1988-12-19 1988-12-19 Novo Industri As Nye n-substituerede azaheterocykliske carboxylsyrer
JP2765876B2 (ja) * 1988-10-24 1998-06-18 科研製薬株式会社 ピリジルケトオキシムエーテル誘導体
DK93791D0 (da) * 1991-05-17 1991-05-17 Novo Nordisk As Nye heterocykliske carboxylsyrer
EP0767174A1 (de) * 1991-11-21 1997-04-09 Ciba-Geigy Ag Neue Aminoalkanphosphinsäuren und ihre Salze
TW266206B (de) * 1993-04-28 1995-12-21 Takeda Pharm Industry Co Ltd
DK74493D0 (da) * 1993-06-23 1993-06-23 Novo Nordisk As Novel heterocyclic chemistry
DK74393D0 (da) * 1993-06-23 1993-06-23 Novo Nordisk As Novel heterocyclic chemistry
US5962449A (en) 1995-04-07 1999-10-05 Novo Nordisk A/S Tricyclic compounds in treating hyperalgesic conditions and NIDDM
ATE189814T1 (de) * 1996-04-15 2000-03-15 Takeda Chemical Industries Ltd Hydroxypyridin-derivate, ihre herstellung und ihre pharmazeutische verwendung
WO1997049403A1 (en) * 1996-06-27 1997-12-31 University College Dublin Use of nipecotic acid or guvacine derivatives for the manufacture of a medicament for the treatment of postischemic neurodegenerative disorders
EP1142584A4 (de) * 1999-01-12 2003-04-16 Takeda Chemical Industries Ltd Zusammensetzungen zur behandlung häufigen harnlassens sowie harninkontinenz

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235931A (en) * 1967-04-05 1980-11-25 Duphar International Research B.V. Compounds having pharmacological properties
FR2162312B1 (de) * 1971-12-10 1975-02-07 Buzas Andre
US4207319A (en) * 1973-10-19 1980-06-10 Albert Rolland S.A. Thienyl or furyl phenyl O-hetero amino alkyl oximes and use thereof
FR2248033B1 (de) * 1973-10-19 1977-03-11 Cerpha
US4148911A (en) * 1977-07-08 1979-04-10 Societe Anonyme Dite Albert Rolland S.A. Method of treating respiratory disorders
DE2851387A1 (de) * 1977-11-28 1979-06-07 Degussa Aminoaethyloxime mit mindestens einem thienylrest und verfahren zu deren herstellung
AU532700B2 (en) * 1979-04-02 1983-10-13 Sumitomo Chemical Company, Limited Diphenylalkanoether
JPS5626863A (en) * 1979-08-13 1981-03-16 Sumitomo Chem Co Ltd Novel diphenylalkanone oxime derivative
US4722930A (en) * 1980-03-01 1988-02-02 John Wyeth And Brother Limited 3-benzoyl-1-[(oxo or thioheteroaryl-ylalkyl)-piperid-4-yl]ureas and derivatives
US4514414A (en) * 1982-10-25 1985-04-30 Smithkline Beckman Corporation N-Substituted pyrrolidineacetic acids and their esters
FI864246A (fi) * 1985-11-08 1987-05-09 Warner Lambert Co N-substituerade 3-piperidin- eller 3-pyridinkarboxylsyror samt deras derivat.
EP0231996B1 (de) * 1986-01-07 1993-10-06 Novo Nordisk A/S Aminosäure-Derivate

Also Published As

Publication number Publication date
NZ229136A (en) 1992-01-29
DK270488D0 (da) 1988-05-18
PH26373A (en) 1992-06-01
DE68917517T2 (de) 1994-12-15
FI93955C (fi) 1995-06-26
FI93955B (fi) 1995-03-15
FI892388A0 (fi) 1989-05-18
JPH0217158A (ja) 1990-01-22
DE68917517D1 (de) 1994-09-22
NO177262B (no) 1995-05-08
CA1337123C (en) 1995-09-26
US5039685A (en) 1991-08-13
IE891533L (en) 1989-11-18
EP0342635B1 (de) 1994-08-17
NO177262C (no) 1995-08-16
JP2824661B2 (ja) 1998-11-11
KR900018058A (ko) 1990-12-20
AU3484589A (en) 1989-11-23
IE66016B1 (en) 1995-11-29
FI892388A (fi) 1989-11-19
AU622178B2 (en) 1992-04-02
NO891970D0 (no) 1989-05-16
ES2058383T3 (es) 1994-11-01
ZA893733B (en) 1990-02-28
EP0342635A1 (de) 1989-11-23
PT90607B (pt) 1995-03-01
NO891970L (no) 1989-11-20
PT90607A (pt) 1989-11-30
IL90313A0 (en) 1989-12-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee