ATE10086T1 - Verfahren zur rueckgewinnung eines peptid enthaltenden produktes und apparat zur durchfuehrung des verfahrens. - Google Patents

Verfahren zur rueckgewinnung eines peptid enthaltenden produktes und apparat zur durchfuehrung des verfahrens.

Info

Publication number
ATE10086T1
ATE10086T1 AT81106358T AT81106358T ATE10086T1 AT E10086 T1 ATE10086 T1 AT E10086T1 AT 81106358 T AT81106358 T AT 81106358T AT 81106358 T AT81106358 T AT 81106358T AT E10086 T1 ATE10086 T1 AT E10086T1
Authority
AT
Austria
Prior art keywords
peptide
ligand
carrier
containing compound
recovering
Prior art date
Application number
AT81106358T
Other languages
English (en)
Inventor
Ulf Thomas Gustav Nylen
Original Assignee
Gambro Lundia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Lundia Ab filed Critical Gambro Lundia Ab
Application granted granted Critical
Publication of ATE10086T1 publication Critical patent/ATE10086T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/12Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
    • B01D15/125Pre-filtration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804Affinity chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804Affinity chromatography
    • B01D15/3809Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14Ultrafiltration; Microfiltration
    • B01D61/147Microfiltration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D61/00Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14Ultrafiltration; Microfiltration
    • B01D61/18Apparatus therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D63/00Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02Hollow fibre modules
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2313/00Details relating to membrane modules or apparatus
    • B01D2313/90Additional auxiliary systems integrated with the module or apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2317/00Membrane module arrangements within a plant or an apparatus
    • B01D2317/02Elements in series

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Water Supply & Treatment (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT81106358T 1980-09-02 1981-08-17 Verfahren zur rueckgewinnung eines peptid enthaltenden produktes und apparat zur durchfuehrung des verfahrens. ATE10086T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8006102A SE8006102L (sv) 1980-09-02 1980-09-02 Sett att utvinna en peptidinnehallande forening samt medel for genomforande av settet
EP81106358A EP0046915B1 (de) 1980-09-02 1981-08-17 Verfahren zur Rückgewinnung eines Peptid enthaltenden Produktes und Apparat zur Durchführung des Verfahrens

Publications (1)

Publication Number Publication Date
ATE10086T1 true ATE10086T1 (de) 1984-11-15

Family

ID=20341647

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81106358T ATE10086T1 (de) 1980-09-02 1981-08-17 Verfahren zur rueckgewinnung eines peptid enthaltenden produktes und apparat zur durchfuehrung des verfahrens.

Country Status (8)

Country Link
US (1) US4474690A (de)
EP (1) EP0046915B1 (de)
JP (1) JPS5777653A (de)
AT (1) ATE10086T1 (de)
DE (1) DE3166968D1 (de)
DK (1) DK382381A (de)
IE (1) IE51726B1 (de)
SE (1) SE8006102L (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE451843B (sv) * 1983-05-09 1987-11-02 Gambro Lundia Ab Forfarande for utvinning av en forening
SE451596B (sv) * 1983-06-22 1987-10-19 Excorim Kb Forfarande for utvinning av protein g
US6258938B1 (en) 1983-10-28 2001-07-10 Ne Medical Center Hospital, Inc. Method for the purification and isolation of blood clotting proteins using conformation specific antibodies
US4963264A (en) * 1985-06-10 1990-10-16 The Standard Oil Company Process for selective dialysis using polymeric affinity adsorbents and size selective membranes
US4770784A (en) * 1985-11-29 1988-09-13 The Standard Oil Company Scrubbing process for high feed concentrations
GB8600582D0 (en) * 1986-01-10 1986-02-19 Ca Minister Nat Defence Purifying biological materials
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
DE3778971D1 (de) * 1986-04-28 1992-06-17 Rohm & Haas Verfahren zum abtrennen und/oder reinigen von biologisch wirksamen substanzen mit teilchenfoermigen polymeren adsorbentien.
JPS62298536A (ja) * 1986-06-17 1987-12-25 Green Cross Corp:The 生理活性物質の自動精製方法および自動精製装置
JPH0283396A (ja) * 1988-09-16 1990-03-23 Soken Kagaku Kk タンパク質の分離方法
US5683916A (en) * 1988-10-31 1997-11-04 Hemasure Inc. Membrane affinity apparatus and purification methods related thereto
CA2001720C (en) * 1988-10-31 2001-10-02 Randal A. Goffe Membrane affinity apparatus and purification methods related thereto
AU6355790A (en) * 1989-08-04 1991-03-11 Peter Grandics An integrated cell culture-protein purification system for the automated production and purification of cell culture products
ATA159993A (de) * 1993-08-10 1995-09-15 Dieter Dr Falkenhagen Anordnung zur elimination von substanzen aus flüssigkeiten
CA2127605A1 (en) * 1993-12-23 1995-06-24 Peter J. Degen Affinity separation method
US6218441B1 (en) 1997-09-18 2001-04-17 Timothy B. Meluch Melt-spun polysulfone semipermeable membranes and methods for making the same
US7144505B2 (en) * 1997-09-18 2006-12-05 Baxter International Inc. Melt-spun polysulfone semipermeable membranes and methods for making the same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3502545A (en) * 1968-09-27 1970-03-24 Monsanto Co Process for the separation of water-soluble polymeric materials from unbound protein or peptide using semiporous gel
NL6906198A (de) * 1969-04-22 1970-10-26
FR2211469A1 (en) * 1972-12-21 1974-07-19 Air Liquide Enzyme purification, esp. ribonuclease, and (chymo) trypsin - by treatment with specific polyinhibitors and extraction or pptn of the complex formed
US3867501A (en) * 1972-12-22 1975-02-18 James W Powers Method for molding candles of varying configuration
FI49086C (fi) * 1973-01-25 1975-03-10 Matti Antero Reunanen Radioimmunologinen määritysmenetelmä.
FR2252351A2 (en) * 1973-11-28 1975-06-20 Air Liquide Isolation of enzymes by selective extraction - partition of polyinhibitor-enzyme complex between water and polyethylene glycol
CH594696A5 (de) * 1975-03-18 1978-01-31 Battelle Memorial Institute
IT1034957B (it) * 1975-04-09 1979-10-10 Snam Progetti Procedimento per la modifica chimica di sostanze proteichemezzi adatti allo scopo e procedimento per la preparazionedi questi
JPS5260720A (en) * 1975-07-18 1977-05-19 Data Products Corp Assembly for sequentially directing types to printing portion and printer
DE2639129C3 (de) * 1976-08-31 1979-10-04 Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf), 3300 Braunschweig Verfahren zur Abtrennung von Enzymen
SE445680B (sv) * 1978-06-20 1986-07-07 Damon Biotech Inc Immunoanalysforfarande och anordning for bestemning av obundna substanser
DE2943016C2 (de) * 1979-10-24 1984-09-06 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Verfahren zur Reinigung von Interferon
US4402874A (en) * 1983-01-10 1983-09-06 Thiokol Corporation Process for the preparation of protein isolates of improved quality from vegetable protein sources using alkali metal borohydrides

Also Published As

Publication number Publication date
JPS5777653A (en) 1982-05-15
EP0046915B1 (de) 1984-10-31
DK382381A (da) 1982-03-03
DE3166968D1 (en) 1984-12-06
IE51726B1 (en) 1987-03-04
US4474690A (en) 1984-10-02
EP0046915A2 (de) 1982-03-10
SE8006102L (sv) 1982-03-03
EP0046915A3 (en) 1982-06-09
IE811883L (en) 1982-03-02

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