ATA216884A - Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen - Google Patents

Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen

Info

Publication number
ATA216884A
ATA216884A AT842168A AT216884A ATA216884A AT A216884 A ATA216884 A AT A216884A AT 842168 A AT842168 A AT 842168A AT 216884 A AT216884 A AT 216884A AT A216884 A ATA216884 A AT A216884A
Authority
AT
Austria
Prior art keywords
lactam
beta
salts
amino
sulphonic acids
Prior art date
Application number
AT842168A
Other languages
English (en)
Other versions
AT381089B (de
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT0055081A external-priority patent/AT378367B/de
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Priority to AT0216884A priority Critical patent/AT381089B/de
Publication of ATA216884A publication Critical patent/ATA216884A/de
Application granted granted Critical
Publication of AT381089B publication Critical patent/AT381089B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT0216884A 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen AT381089B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0216884A AT381089B (de) 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18889380A 1980-09-29 1980-09-29
AT0055081A AT378367B (de) 1981-02-06 1981-02-06 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen
AT0216884A AT381089B (de) 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen

Publications (2)

Publication Number Publication Date
ATA216884A true ATA216884A (de) 1986-01-15
AT381089B AT381089B (de) 1986-08-25

Family

ID=26884568

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0216984A AT380472B (de) 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen
AT0216884A AT381089B (de) 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0216984A AT380472B (de) 1980-09-29 1984-07-05 Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen

Country Status (2)

Country Link
US (1) US4775670A (de)
AT (2) AT380472B (de)

Families Citing this family (39)

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US5112968A (en) * 1989-07-28 1992-05-12 E. R. Squibb & Sons, Inc. Monobactam hydrazide derivatives
CA2024282A1 (en) * 1989-09-21 1991-03-22 Peter H. Ermann Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics
US5030724A (en) * 1990-01-22 1991-07-09 E. R. Squibb & Sons, Inc. Monobactam hydrazides containing catechol sulfonic acid groups
US5077432A (en) * 1990-01-22 1991-12-31 E. R. Squibb & Sons, Inc. Monobactam hydrazides containing catechol sulfonic acid groups
US5194604A (en) * 1990-06-29 1993-03-16 E. R. Squibb & Sons, Inc. Process and intermediates for beta-lactams having aminothiazole(iminooxyacetic acid)acetic acid sidechains
ZA918014B (en) * 1990-11-05 1992-07-29 Squibb & Sons Inc Heteroaroyl derivatives of monocyclic beta-lactam antibiotics
BR9206371A (pt) * 1991-08-14 1995-10-17 Procter & Gamble Pharma Novas uréias cíclicas utilzáveis como agentes antirrítmicos e antifibrilatórios
ES2180537T3 (es) * 1991-08-14 2003-02-16 Procter & Gamble Pharma Nuevas ureas 4-oxociclicas, utilizables como agentes antiarritmicos o antifibrilantes.
JPH06510285A (ja) * 1991-08-14 1994-11-17 プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド 抗不整脈及び抗細動剤として有用な環状ウレタン類
US5250691A (en) * 1991-09-09 1993-10-05 E. R. Squibb & Sons, Inc. Heteroaryl derivatives of monocyclic beta-lactam antibiotics
US5888998A (en) * 1997-04-24 1999-03-30 Synphar Laboratories, Inc. 2-oxo-1-azetidine sulfonic acid derivatives as potent β-lactamase inhibitors
US5994340A (en) * 1997-08-29 1999-11-30 Synphar Laboratories, Inc. Azetidinone derivatives as β-lactamase inhibitors
US6335324B1 (en) 1998-06-25 2002-01-01 Bristol-Myers Squibb Co. Beta lactam compounds and their use as inhibitors of tryptase
US6498170B2 (en) * 2000-07-17 2002-12-24 Wyeth Cyclamine sulfonamides as β-3 adrenergic receptor agonists
US7214364B2 (en) * 2000-12-27 2007-05-08 Corus Pharma, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
DK1353647T3 (da) 2000-12-27 2011-06-14 Gilead Sciences Inc Inhalerbar aztreonam til behandling og forebyggelse af bakterielle lungeinfektioner
US7138419B2 (en) * 2000-12-27 2006-11-21 Corus Pharma, Inc. Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
WO2003011298A1 (en) * 2001-08-03 2003-02-13 Chirologix Pharmaceuticals Inc. Antibacterial oxazinones and methods for their use and synthesis
WO2003018565A1 (en) * 2001-08-29 2003-03-06 Chirologix Pharmaceuticals Inc. Method for synthesizing oxazinones
CN1681812A (zh) 2002-08-05 2005-10-12 特瓦药厂有限公司 氨曲南的制备
WO2004103999A1 (en) * 2003-05-15 2004-12-02 TEVA Gyógyszergyár Részvénytársaság AZTREONAM β POLYMORPH WITH VERY LOW RESIDUAL SOLVENT CONTENT
DE112004001191B4 (de) 2003-07-02 2017-11-09 Corus Pharma Inc. Verfahren zur Herstellung des L-Lysin-Salzes von Aztreonam und Verfahren zur Bestimmung des Verunreinigungsgrads in einem amorphen Aztreonam Lysin-Salz
US20050005101A1 (en) * 2003-07-03 2005-01-06 Yenduri Bhargava K. Kernel cryptographic module signature verification system and method
EP1888576B1 (de) * 2005-05-09 2009-02-18 Sicor Inc. Herstellungsverfahren für aztreonam
HRP20110841T1 (hr) * 2005-12-07 2012-01-31 Basilea Pharmaceutica Ag Korisni monobaktamski antibiotici
CN100469777C (zh) * 2006-12-15 2009-03-18 北京赛科药业有限责任公司 氨曲南的制备方法
CN100486964C (zh) * 2006-12-15 2009-05-13 北京赛科药业有限责任公司 一种合成（2s-反式）-3-氨基-2-甲基-4-氧代-1-氮杂环丁基磺酸的方法
CN102584811A (zh) * 2011-12-29 2012-07-18 蚌埠丰原涂山制药有限公司 一种氨曲南的制备方法
CN102807519A (zh) * 2012-08-14 2012-12-05 济南瑞丰医药科技有限公司 一种氨曲南侧链小环的制备方法
WO2015148379A1 (en) 2014-03-24 2015-10-01 Novartis Ag Monobactam organic compounds for the treatment of bacterial infections
CN108137573B (zh) 2015-09-23 2021-06-11 诺华股份有限公司 单环内酰胺抗生素的盐和固体形式
CN105481731A (zh) * 2015-12-21 2016-04-13 山东金城医药化工股份有限公司 N-磺基-n-苄氧羰基-o-甲烷磺酸基-l-苏氨酸酰胺钠盐的制备方法
CN108341764B (zh) * 2017-01-25 2021-02-09 重庆常捷医药有限公司 一种氨曲南母核的合成方法
WO2019026004A2 (en) 2017-08-02 2019-02-07 Novartis Ag CHEMICAL PROCESS FOR THE PREPARATION OF ANTIBIOTIC MONOBACTAM AND ITS INTERMEDIATES
US10280161B2 (en) * 2017-10-02 2019-05-07 Arixa Pharmaceuticals, Inc. Aztreonam derivatives and uses thereof
US11565999B2 (en) 2019-04-25 2023-01-31 Arixa Pharmaceuticals, Inc. Methods of synthesizing aztreonam derivatives
CN112279783B (zh) * 2020-09-27 2022-09-02 山东新和成精化科技有限公司 一种超临界条件下制备3-羟基丙腈的方法
CN113072475A (zh) * 2021-03-30 2021-07-06 山东金城医药化工有限公司 氨曲南中间体的合成方法
US20250009891A1 (en) * 2021-08-20 2025-01-09 University Of Notre Dame Du Lac Conjugates of monocyclic beta-lactams and siderophore mimetics

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US3971772A (en) * 1975-01-06 1976-07-27 E. R. Squibb & Sons, Inc. Steroidal[16α,17-b]1,4-dioxanes and Steroidal[16α,17-b]1,4-dioxins
JPS6046955B2 (ja) * 1977-12-30 1985-10-18 武田薬品工業株式会社 抗生物質ｇ−６３０２
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US4529698A (en) * 1981-01-19 1985-07-16 E. R. Squibb & Sons, Inc. Process for preparing a 2-oxo-1-azetidinesulfonic acid salt
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Also Published As

Publication number Publication date
US4775670A (en) 1988-10-04
ATA216984A (de) 1985-10-15
AT380472B (de) 1986-05-26
AT381089B (de) 1986-08-25

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
ELA Expired due to lapse of time