ATA216884A - Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen - Google Patents
Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzenInfo
- Publication number
- ATA216884A ATA216884A AT842168A AT216884A ATA216884A AT A216884 A ATA216884 A AT A216884A AT 842168 A AT842168 A AT 842168A AT 216884 A AT216884 A AT 216884A AT A216884 A ATA216884 A AT A216884A
- Authority
- AT
- Austria
- Prior art keywords
- lactam
- beta
- salts
- amino
- sulphonic acids
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0216884A AT381089B (de) | 1980-09-29 | 1984-07-05 | Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18889380A | 1980-09-29 | 1980-09-29 | |
AT0055081A AT378367B (de) | 1981-02-06 | 1981-02-06 | Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen |
AT0216884A AT381089B (de) | 1980-09-29 | 1984-07-05 | Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA216884A true ATA216884A (de) | 1986-01-15 |
AT381089B AT381089B (de) | 1986-08-25 |
Family
ID=26884568
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0216884A AT381089B (de) | 1980-09-29 | 1984-07-05 | Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen |
AT0216984A AT380472B (de) | 1980-09-29 | 1984-07-05 | Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0216984A AT380472B (de) | 1980-09-29 | 1984-07-05 | Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen |
Country Status (2)
Country | Link |
---|---|
US (1) | US4775670A (de) |
AT (2) | AT381089B (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5112968A (en) * | 1989-07-28 | 1992-05-12 | E. R. Squibb & Sons, Inc. | Monobactam hydrazide derivatives |
CA2024282A1 (en) * | 1989-09-21 | 1991-03-22 | Peter H. Ermann | Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics |
US5030724A (en) * | 1990-01-22 | 1991-07-09 | E. R. Squibb & Sons, Inc. | Monobactam hydrazides containing catechol sulfonic acid groups |
US5077432A (en) * | 1990-01-22 | 1991-12-31 | E. R. Squibb & Sons, Inc. | Monobactam hydrazides containing catechol sulfonic acid groups |
US5194604A (en) * | 1990-06-29 | 1993-03-16 | E. R. Squibb & Sons, Inc. | Process and intermediates for beta-lactams having aminothiazole(iminooxyacetic acid)acetic acid sidechains |
ZA918014B (en) * | 1990-11-05 | 1992-07-29 | Squibb & Sons Inc | Heteroaroyl derivatives of monocyclic beta-lactam antibiotics |
RU2221788C2 (ru) * | 1991-08-14 | 2004-01-20 | Проктер энд Гэмбл Фармасьютикалз | Оксоциклические соединения мочевины, фармацевтическая композиция, способ лечения |
ATE226202T1 (de) * | 1991-08-14 | 2002-11-15 | Procter & Gamble Pharma | Zyklische harnstoffe mit antiarrhythmischer und antifibrillatorischer wirkung |
ES2141725T3 (es) * | 1991-08-14 | 2000-04-01 | Procter & Gamble Pharma | Derivados de oxazolidinona, utiles como agentes antiarritmicos y antifibriladores. |
US5250691A (en) * | 1991-09-09 | 1993-10-05 | E. R. Squibb & Sons, Inc. | Heteroaryl derivatives of monocyclic beta-lactam antibiotics |
US5888998A (en) * | 1997-04-24 | 1999-03-30 | Synphar Laboratories, Inc. | 2-oxo-1-azetidine sulfonic acid derivatives as potent β-lactamase inhibitors |
US5994340A (en) * | 1997-08-29 | 1999-11-30 | Synphar Laboratories, Inc. | Azetidinone derivatives as β-lactamase inhibitors |
US6335324B1 (en) | 1998-06-25 | 2002-01-01 | Bristol-Myers Squibb Co. | Beta lactam compounds and their use as inhibitors of tryptase |
US6498170B2 (en) * | 2000-07-17 | 2002-12-24 | Wyeth | Cyclamine sulfonamides as β-3 adrenergic receptor agonists |
BRPI0116757B8 (pt) | 2000-12-27 | 2021-05-25 | Corus Pharma Inc | composição, formulação e produto contendo aztreonam e uso do mesmo para aplicação via inalatória |
US7138419B2 (en) * | 2000-12-27 | 2006-11-21 | Corus Pharma, Inc. | Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate |
US7214364B2 (en) | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
AU2002322247A1 (en) * | 2001-08-03 | 2003-02-17 | Chirologix Pharmaceutical Inc. | Antibacterial oxazinones and methods for their use and synthesis |
US20030232820A1 (en) * | 2001-08-29 | 2003-12-18 | Saul Wolfe | Method for synthesizing oxazinones |
EP1527072A1 (de) | 2002-08-05 | 2005-05-04 | Teva Gyogyszergyar Reszvenytarsasag | Herstellung von aztreonam |
US7452991B2 (en) * | 2003-05-15 | 2008-11-18 | Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság | Aztreonam β polymorph with very low residual solvent content |
JP4741487B2 (ja) | 2003-07-02 | 2011-08-03 | コーラス ファーマ,インコーポレイティド | アズトレオナムl−リジン及びそれを調製するための方法 |
US20050005101A1 (en) * | 2003-07-03 | 2005-01-06 | Yenduri Bhargava K. | Kernel cryptographic module signature verification system and method |
ES2321336T3 (es) * | 2005-05-09 | 2009-06-04 | Sicor Inc. | Procedimiento para la fabricacion de aztreonam. |
KR101448553B1 (ko) * | 2005-12-07 | 2014-10-13 | 바실리어 파마슈티카 아게 | 베타-락타마아제 저해제 및 모노박탐 항생물질의 유용한 조합 |
CN100469777C (zh) * | 2006-12-15 | 2009-03-18 | 北京赛科药业有限责任公司 | 氨曲南的制备方法 |
CN100486964C (zh) * | 2006-12-15 | 2009-05-13 | 北京赛科药业有限责任公司 | 一种合成(2s-反式)-3-氨基-2-甲基-4-氧代-1-氮杂环丁基磺酸的方法 |
CN102584811A (zh) * | 2011-12-29 | 2012-07-18 | 蚌埠丰原涂山制药有限公司 | 一种氨曲南的制备方法 |
CN102807519A (zh) * | 2012-08-14 | 2012-12-05 | 济南瑞丰医药科技有限公司 | 一种氨曲南侧链小环的制备方法 |
SG11201606711UA (en) | 2014-03-24 | 2016-10-28 | Novartis Ag | Monobactam organic compounds for the treatment of bacterial infections |
EP3353175B1 (de) | 2015-09-23 | 2020-08-12 | Novartis AG | Salze und feste formen eines monobactam-antibiotikums |
CN105481731A (zh) * | 2015-12-21 | 2016-04-13 | 山东金城医药化工股份有限公司 | N-磺基-n-苄氧羰基-o-甲烷磺酸基-l-苏氨酸酰胺钠盐的制备方法 |
CN108341764B (zh) * | 2017-01-25 | 2021-02-09 | 重庆常捷医药有限公司 | 一种氨曲南母核的合成方法 |
CN111094281B (zh) | 2017-08-02 | 2023-08-29 | 诺华股份有限公司 | 用于制备单内酰胺抗生素的化学方法及其中间体 |
CA3077474A1 (en) * | 2017-10-02 | 2019-04-11 | Arixa Pharmaceuticals, Inc. | Aztreonam derivatives and uses thereof |
WO2020219258A1 (en) | 2019-04-25 | 2020-10-29 | Arixa Pharmaceuticals, Inc. | Methods of synthesizing aztreonam derivatives |
CN112279783B (zh) * | 2020-09-27 | 2022-09-02 | 山东新和成精化科技有限公司 | 一种超临界条件下制备3-羟基丙腈的方法 |
CN113072475A (zh) * | 2021-03-30 | 2021-07-06 | 山东金城医药化工有限公司 | 氨曲南中间体的合成方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3048581A (en) * | 1960-04-25 | 1962-08-07 | Olin Mathieson | Acetals and ketals of 16, 17-dihydroxy steroids |
US3971772A (en) * | 1975-01-06 | 1976-07-27 | E. R. Squibb & Sons, Inc. | Steroidal[16α,17-b]1,4-dioxanes and Steroidal[16α,17-b]1,4-dioxins |
JPS6046955B2 (ja) * | 1977-12-30 | 1985-10-18 | 武田薬品工業株式会社 | 抗生物質g−6302 |
JPS5549394A (en) * | 1978-10-03 | 1980-04-09 | Takeda Chem Ind Ltd | Antibiotic substance sb-72310 |
DE3069587D1 (en) * | 1979-06-08 | 1984-12-13 | Takeda Chemical Industries Ltd | 1-sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof |
JPS55164672A (en) * | 1979-06-08 | 1980-12-22 | Takeda Chem Ind Ltd | Azetidine derivative and its preparation |
US4533660A (en) * | 1980-10-31 | 1985-08-06 | E. R. Squibb & Sons, Inc. | Antibacterial O-sulfated β-lactam hydroxamic acids |
US4529698A (en) * | 1981-01-19 | 1985-07-16 | E. R. Squibb & Sons, Inc. | Process for preparing a 2-oxo-1-azetidinesulfonic acid salt |
US4483797A (en) * | 1981-04-27 | 1984-11-20 | E. R. Squibb & Sons, Inc. | (S)-3-Isocyanato-2-oxo-1-azetidinesulfonic acids |
US4734496A (en) * | 1981-05-29 | 1988-03-29 | E. R. Squibb & Sons, Inc. | 4-amino derivatives of 2-oxo-1-azetidinesulfonic acid salts |
US4501697A (en) * | 1983-06-17 | 1985-02-26 | E. R. Squibb & Sons, Inc. | 4-[[(Amidomethyl)oxy]methyl]-2-oxo-1-azetidinesulfonic acid salts |
US4610824A (en) * | 1984-10-09 | 1986-09-09 | E. R. Squibb & Sons, Inc. | Hydrazide derivatives of monocyclic beta-lactam antibiotics |
US4647660A (en) * | 1985-05-02 | 1987-03-03 | E. R. Squibb & Sons, Inc. | 3-acylamino-2-oxo-1-azetidinesulfonic acids |
US4632985A (en) * | 1985-06-03 | 1986-12-30 | E. R. Squibb & Sons, Inc. | 3-acylamino-2-oxo-1-azetidinesulfonic acids |
US4638062A (en) * | 1985-06-17 | 1987-01-20 | E. R. Squibb & Sons, Inc. | 3-acylamino-2-oxo-1-azetidinesulfonic acids |
-
1981
- 1981-01-19 US US06/226,562 patent/US4775670A/en not_active Expired - Lifetime
-
1984
- 1984-07-05 AT AT0216884A patent/AT381089B/de not_active IP Right Cessation
- 1984-07-05 AT AT0216984A patent/AT380472B/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4775670A (en) | 1988-10-04 |
AT380472B (de) | 1986-05-26 |
AT381089B (de) | 1986-08-25 |
ATA216984A (de) | 1985-10-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATA216884A (de) | Verfahren zur herstellung von neuen 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen | |
AT381945B (de) | Verfahren zur herstellung von neuen cephemverbindungen und ihren pyhsiologisch vertraeglichen saeureadditionssalzen | |
AT375639B (de) | Verfahren zur herstellung von neuen carbazolyl-(4)-oxy-propanolamin-derivaten und ihren salzen | |
AT381934B (de) | Verfahren zur herstellung von neuen indolderivaten und ihren salzen | |
ATA143781A (de) | Verfahren zur herstellung von neuen diaminopyridinen und ihren salzen | |
AT370408B (de) | Verfahren zur herstellung von neuen phenylaethanolaminen und von salzen hiervon | |
ATA463779A (de) | Verfahren zur herstellung von neuen phenylaethanolaminen und salzen hirvon | |
AT360533B (de) | Verfahren zur herstellung von neuen trans- -hexahydropyrido-indolen und ihren saeure- additionssalzen | |
ATA750879A (de) | Verfahren zur herstellung von neuen 1,2,4,5-tetra--alkyl-4-aryl-piperidinen und ihren salzen | |
AT379378B (de) | Verfahren zur herstellung von neuen phenylalkylaminen und ihren salzen | |
AT377974B (de) | Verfahren zur herstellung von neuen aromatischen carbonsaeuren und ihren salzen | |
AT370407B (de) | Verfahren zur herstellung von neuen 9-aminoalkyfluorenen und ihren salzen | |
AT374468B (de) | Verfahren zur herstellung von neuen substituierten chinazolinen und ihren salzen | |
AT358046B (de) | Verfahren zur herstellung von neuen trans-5a- -aryl-decahydrobenzazepinen und ihren saeure- additionssalzen | |
AT364377B (de) | Verfahren zur herstellung von neuen n-mercaptoalkanoyl-4-aminocarbonyloxyprolinen und ihren salzen | |
AT386203B (de) | Verfahren zur herstellung von neuen apovincaminol-derivaten und ihren saeureadditionssalzen | |
ATA315781A (de) | Verfahren zur herstellung von neuen pyridinylaminophenolen und deren salzen | |
ATA55081A (de) | Verfahren zur herstellung von 3-amino-beta-lactam-1-sulfonsaeuren und ihren salzen | |
ATA298486A (de) | Verfahren zur herstellung von neuen imidazochinoxalinen und ihren salzen | |
ATA318484A (de) | Verfahren zur herstellung von neuen indolverbindungen und ihren salzen | |
AT357156B (de) | Verfahren zur herstellung von neuen thio- xanthen-verbindungen und ihren salzen | |
ATA214383A (de) | Verfahren zur herstellung von neuen substituierten chinazolinen und ihren salzen | |
AT379587B (de) | Verfahren zur herstellung von neuen phenylalkylaminen und ihren salzen | |
AT379586B (de) | Verfahren zur herstellung von neuen phenylalkylaminen und ihren salzen | |
ATA436783A (de) | Verfahren zur herstellung von neuen phenylalkylaminen und ihren salzen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
ELA | Expired due to lapse of time |