AT360534B - Verfahren zur herstellung von neuen nicotinamido- und nicotinamidoalkyl-benzoe- saeuren und deren derivaten - Google Patents
Verfahren zur herstellung von neuen nicotinamido- und nicotinamidoalkyl-benzoe- saeuren und deren derivatenInfo
- Publication number
- AT360534B AT360534B AT118178A AT118178A AT360534B AT 360534 B AT360534 B AT 360534B AT 118178 A AT118178 A AT 118178A AT 118178 A AT118178 A AT 118178A AT 360534 B AT360534 B AT 360534B
- Authority
- AT
- Austria
- Prior art keywords
- nicotinamidoalkyl
- benzoe
- nicotinamido
- derivatives
- acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT44980A AT360541B (de) | 1977-02-18 | 1980-01-28 | Verfahren zur herstellung von neuen nicotinamido- und nicotinamidoalkylbenzoesaeuren und deren derivaten |
| AT44880A AT360540B (de) | 1977-02-18 | 1980-01-28 | Verfahren zur herstellung von neuen nicotinamido- und nicotinamidoalkylbenzoesaeuren und deren derivaten |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772706977 DE2706977A1 (de) | 1977-02-18 | 1977-02-18 | Benzoesaeuren und deren derivate sowie verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA118178A ATA118178A (de) | 1980-06-15 |
| AT360534B true AT360534B (de) | 1981-01-12 |
Family
ID=6001556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT118178A AT360534B (de) | 1977-02-18 | 1978-02-17 | Verfahren zur herstellung von neuen nicotinamido- und nicotinamidoalkyl-benzoe- saeuren und deren derivaten |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4181658A (de) |
| JP (1) | JPS53103477A (de) |
| AT (1) | AT360534B (de) |
| AU (1) | AU3337678A (de) |
| BE (1) | BE864112A (de) |
| CA (1) | CA1113473A (de) |
| CH (1) | CH645625A5 (de) |
| DE (1) | DE2706977A1 (de) |
| DK (1) | DK71278A (de) |
| ES (1) | ES466910A1 (de) |
| FI (1) | FI780491A (de) |
| FR (1) | FR2381028A1 (de) |
| GB (1) | GB1601195A (de) |
| GR (1) | GR78247B (de) |
| IL (1) | IL54058A0 (de) |
| NL (1) | NL7801859A (de) |
| NO (1) | NO780558L (de) |
| PT (1) | PT67672B (de) |
| SE (1) | SE7801885L (de) |
| ZA (1) | ZA78946B (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3063878D1 (en) * | 1979-07-13 | 1983-07-28 | Thomae Gmbh Dr K | Derivatives of carboxylic acids, their preparation and medicaments containing them |
| DE3211934A1 (de) * | 1982-03-31 | 1983-10-13 | Hoechst Ag, 6230 Frankfurt | Salicylsaeurederivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
| EP0195582B1 (de) * | 1985-03-14 | 1990-01-24 | SMITH KLINE DAUELSBERG GmbH | 5-Aminosalicylsäurederivate von nicht-steroidalen entzündungshemmenden Sauren |
| NZ337698A (en) * | 1997-04-04 | 2001-07-27 | Pfizer Prod Inc | Nicotinamide derivatives for selective inhibition of phosphodiesterase type 4 (PDE4) and the production of tumour necrosis factor (TNF) useful for the treatment of respiratory, rheumatoid and allergic diseases |
| KR100884877B1 (ko) * | 2000-12-28 | 2009-02-23 | 다이이찌 세이야꾸 가부시기가이샤 | Ｖｌａ-４ 저해제 |
| US7250518B2 (en) * | 2001-01-31 | 2007-07-31 | Pfizer Inc. | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes |
| EP1229034B1 (de) * | 2001-01-31 | 2005-04-13 | Pfizer Products Inc. | Nikotinsäureamid-Derivate und ihre Mimetika als Inhibitoren von PDE4-Isozyms |
| TW200500341A (en) * | 2002-11-12 | 2005-01-01 | Astrazeneca Ab | Novel compounds |
| TWI340134B (en) * | 2003-07-24 | 2011-04-11 | Daiichi Seiyaku Co | Cyclohexanecarboxylic acids |
| SE0302323D0 (sv) * | 2003-08-28 | 2003-08-28 | Astrazeneca Ab | Novel compounds |
| SE0302324D0 (sv) * | 2003-08-28 | 2003-08-28 | Astrazeneca Ab | Novel compounds |
| AU2004268839A1 (en) | 2003-09-03 | 2005-03-10 | Pfizer Inc. | Phenyl or pyridyl amide compounds as prostaglandin E2 antagonists |
| SE0302486D0 (sv) | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | Novel compounds |
| TW200700392A (en) * | 2005-03-16 | 2007-01-01 | Astrazeneca Ab | Novel compounds |
| TW200808771A (en) * | 2006-05-08 | 2008-02-16 | Astrazeneca Ab | Novel compounds II |
| TW200808763A (en) * | 2006-05-08 | 2008-02-16 | Astrazeneca Ab | Novel compounds I |
| CN101541783B (zh) | 2006-06-30 | 2014-10-01 | 苏尼西斯制药有限公司 | 吡啶酮基pdk1抑制剂 |
| MX2010004673A (es) * | 2007-11-06 | 2010-05-27 | Astrazeneca Ab | Algunos derivados de 2-pirazinona y su uso como inhibidores de elastasa de los neutrofilos. |
| TW201036957A (en) * | 2009-02-20 | 2010-10-16 | Astrazeneca Ab | Novel salt 628 |
| TWI504395B (zh) | 2009-03-10 | 2015-10-21 | Substituted 3-amino-2-mercaptoquinoline as a KCNQ2 / 3 modifier | |
| TW201038565A (en) | 2009-03-12 | 2010-11-01 | Gruenenthal Gmbh | Substituted 2-mercapto-3-aminopyridines as KCNQ2/3 modulators |
| TWI461197B (zh) | 2009-03-12 | 2014-11-21 | 2-mercaptoquinoline-3-carboxamide as a KCNQ2 / 3 modifier | |
| AU2010302420B2 (en) * | 2009-10-02 | 2013-07-04 | Astrazeneca Ab | 2-pyridone compounds used as inhibitors of neutrophil elastase |
| JP5887345B2 (ja) | 2010-08-27 | 2016-03-16 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | Ｋｃｎｑ２／３調節因子としての置換２−アミノ−キノリン−３−カルボキサミド |
| PL2609086T3 (pl) | 2010-08-27 | 2015-07-31 | Gruenenthal Gmbh | Podstawione 2-okso- i 2-tiookso-dihydrochinolino-3-karboksyamidy jako modulatory KCNQ2/3 |
| RU2595894C2 (ru) | 2010-08-27 | 2016-08-27 | Грюненталь Гмбх | Замещенные 2-окси-хинолин-3-карбоксамиды в качестве модуляторов kcnq2/3 |
| AR082813A1 (es) | 2010-09-01 | 2013-01-09 | Gruenenthal Gmbh | 1-oxo-dihidroisoquinolin-3-carboxamidas sustituidas como moduladores de kcnq2/3 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3879403A (en) * | 1973-05-04 | 1975-04-22 | Pfizer | Benzenesulfonylurea derivatives |
| DE2406200A1 (de) * | 1974-02-09 | 1975-08-14 | Bayer Ag | Verfahren zur herstellung von neuen 3,6-diamino-3,4-dihydropyridonen-2 und ihre verwendung als arzneimittel |
| DE2500157C2 (de) * | 1975-01-03 | 1983-09-15 | Hoechst Ag, 6230 Frankfurt | N-Acyl-4-(2-aminoäthyl)-benzoesäuren, deren Salze und Ester, Verfahren zu deren Herstellung und deren Verwendung |
-
1977
- 1977-02-18 DE DE19772706977 patent/DE2706977A1/de not_active Withdrawn
-
1978
- 1978-02-13 ES ES466910A patent/ES466910A1/es not_active Expired
- 1978-02-14 FR FR7804116A patent/FR2381028A1/fr active Granted
- 1978-02-15 CH CH165978A patent/CH645625A5/de not_active IP Right Cessation
- 1978-02-15 FI FI780491A patent/FI780491A/fi not_active Application Discontinuation
- 1978-02-16 IL IL54058A patent/IL54058A0/xx unknown
- 1978-02-16 US US05/878,602 patent/US4181658A/en not_active Expired - Lifetime
- 1978-02-17 NL NL7801859A patent/NL7801859A/xx not_active Application Discontinuation
- 1978-02-17 DK DK71278A patent/DK71278A/da unknown
- 1978-02-17 SE SE7801885A patent/SE7801885L/xx unknown
- 1978-02-17 PT PT67672A patent/PT67672B/de unknown
- 1978-02-17 CA CA297,158A patent/CA1113473A/en not_active Expired
- 1978-02-17 AT AT118178A patent/AT360534B/de not_active IP Right Cessation
- 1978-02-17 ZA ZA00780946A patent/ZA78946B/xx unknown
- 1978-02-17 AU AU33376/78A patent/AU3337678A/en active Pending
- 1978-02-17 NO NO780558A patent/NO780558L/no unknown
- 1978-02-18 JP JP1714078A patent/JPS53103477A/ja active Pending
- 1978-02-20 BE BE185297A patent/BE864112A/xx not_active IP Right Cessation
- 1978-02-20 GB GB6598/78A patent/GB1601195A/en not_active Expired
-
1981
- 1981-03-06 GR GR55473A patent/GR78247B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU3337678A (en) | 1979-08-23 |
| FR2381028A1 (fr) | 1978-09-15 |
| DK71278A (da) | 1978-08-19 |
| GR78247B (de) | 1984-09-26 |
| SE7801885L (sv) | 1978-08-18 |
| NO780558L (no) | 1978-08-21 |
| GB1601195A (en) | 1981-10-28 |
| JPS53103477A (en) | 1978-09-08 |
| DE2706977A1 (de) | 1978-08-24 |
| IL54058A0 (en) | 1978-04-30 |
| ES466910A1 (es) | 1978-10-01 |
| CH645625A5 (de) | 1984-10-15 |
| FR2381028B1 (de) | 1980-10-24 |
| FI780491A (fi) | 1978-08-19 |
| US4181658A (en) | 1980-01-01 |
| NL7801859A (nl) | 1978-08-22 |
| PT67672A (de) | 1978-03-01 |
| ATA118178A (de) | 1980-06-15 |
| PT67672B (de) | 1979-10-10 |
| BE864112A (fr) | 1978-08-21 |
| ZA78946B (en) | 1979-01-31 |
| CA1113473A (en) | 1981-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |