AT345842B - Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxyden und salzen - Google Patents

Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxyden und salzen

Info

Publication number
AT345842B
AT345842B AT107076A AT107076A AT345842B AT 345842 B AT345842 B AT 345842B AT 107076 A AT107076 A AT 107076A AT 107076 A AT107076 A AT 107076A AT 345842 B AT345842 B AT 345842B
Authority
AT
Austria
Prior art keywords
oxydes
salts
producing new
morpholine derivatives
new morpholine
Prior art date
Application number
AT107076A
Other languages
German (de)
English (en)
Other versions
ATA107076A (de
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to AT107076A priority Critical patent/AT345842B/de
Priority to CH1581976A priority patent/CH623317A5/de
Priority to AU21099/77A priority patent/AU506427B2/en
Priority to YU60/77A priority patent/YU39983B/xx
Priority to SI7710060A priority patent/SI7710060A8/sl
Priority to AR266340A priority patent/AR214307A1/es
Priority to FI770356A priority patent/FI65426C/fi
Priority to NLAANVRAGE7701144,A priority patent/NL179382C/xx
Priority to DK51677A priority patent/DK148824C/da
Priority to ZA770746A priority patent/ZA77746B/xx
Priority to IL51406A priority patent/IL51406A/xx
Priority to CA271,635A priority patent/CA1076112A/fr
Priority to IE296/77A priority patent/IE44482B1/en
Priority to NZ183316A priority patent/NZ183316A/xx
Priority to MC771233A priority patent/MC1136A1/fr
Priority to LU76771A priority patent/LU76771A1/xx
Priority to PH19452A priority patent/PH12847A/en
Priority to FR7704087A priority patent/FR2340940A1/fr
Priority to JP1431377A priority patent/JPS52100476A/ja
Priority to DE2706179A priority patent/DE2706179C2/de
Priority to ES455907A priority patent/ES455907A1/es
Priority to NO770488A priority patent/NO148417C/no
Priority to GR52790A priority patent/GR62413B/el
Priority to BE174926A priority patent/BE851422A/fr
Priority to SE7701669A priority patent/SE426822B/xx
Priority to PT66195A priority patent/PT66195B/fr
Priority to GB6215/77A priority patent/GB1512194A/en
Priority to AR268800A priority patent/AR212554A1/es
Priority to AT25678A priority patent/AT349480B/de
Priority to AT25778A priority patent/AT349481B/de
Priority to AT25578A priority patent/AT349479B/de
Priority to AT25878A priority patent/AT349482B/de
Publication of ATA107076A publication Critical patent/ATA107076A/de
Priority to ES467448A priority patent/ES467448A1/es
Priority to ES467455A priority patent/ES467455A1/es
Priority to ES467449A priority patent/ES467449A1/es
Application granted granted Critical
Publication of AT345842B publication Critical patent/AT345842B/de
Priority to CH554580A priority patent/CH623576A5/de
Priority to CH554480A priority patent/CH622787A5/de
Priority to CH554380A priority patent/CH622786A5/de
Priority to CH554680A priority patent/CH623577A5/de
Priority to HRP-60/77A priority patent/HRP930495B1/xx
Priority to LU88300C priority patent/LU88300I2/de
Priority to NL930082C priority patent/NL930082I2/nl
Priority to NO1994008C priority patent/NO1994008I1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT107076A 1976-02-16 1976-02-16 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxyden und salzen AT345842B (de)

Priority Applications (43)

Application Number Priority Date Filing Date Title
AT107076A AT345842B (de) 1976-02-16 1976-02-16 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxyden und salzen
CH1581976A CH623317A5 (en) 1976-02-16 1976-12-16 Process for the preparation of benzamides
AU21099/77A AU506427B2 (en) 1976-02-16 1977-01-06 Benzamides
YU60/77A YU39983B (en) 1976-02-16 1977-01-12 Process for obtaining new benzamides
SI7710060A SI7710060A8 (en) 1976-02-16 1977-01-12 Process for obtaining new benzamides
AR266340A AR214307A1 (es) 1976-02-16 1977-01-27 Procedimiento para la preparacion de derivados de n-(2-morfolinoetil)-benzamida
FI770356A FI65426C (fi) 1976-02-16 1977-02-01 Analogifoerfarande foer framstaellning av nya farmakologiskt verkande n-(2-morfolinoetyl)bensamider
NLAANVRAGE7701144,A NL179382C (nl) 1976-02-16 1977-02-03 Werkwijze voor het bereiden van geneesmiddelen op basis van een in de fenylgroep gesubstitueerd n-(2-morfolinoethyl)-benzamide en werkwijze voor het bereiden van deze benzamiden.
DK51677A DK148824C (da) 1976-02-16 1977-02-08 Analogifremgangsmaade til fremstilling af farmakologisk virksomme n-(2-morpholinoethyl)-benzamider eller syreadditionssalte deraf
ZA770746A ZA77746B (en) 1976-02-16 1977-02-09 Benzamides
IL51406A IL51406A (en) 1976-02-16 1977-02-09 N-(morpholineothyl)benzamide derivatives their manufacture and pharmaceutical compositions containing them
CA271,635A CA1076112A (fr) 1976-02-16 1977-02-11 Benzamides
IE296/77A IE44482B1 (en) 1976-02-16 1977-02-11 Benzamides
NZ183316A NZ183316A (en) 1976-02-16 1977-02-11 4-substituted-n-(2-morphol-inoethyl) benzamides
LU76771A LU76771A1 (fr) 1976-02-16 1977-02-14
PH19452A PH12847A (en) 1976-02-16 1977-02-14 Benzamide derivatives
FR7704087A FR2340940A1 (fr) 1976-02-16 1977-02-14 Nouveaux benzamides, leur procede de preparation et leur application en tant que medicaments notamment destines au traitement d'etats depressifs
JP1431377A JPS52100476A (en) 1976-02-16 1977-02-14 Benzamide derivatives
DE2706179A DE2706179C2 (de) 1976-02-16 1977-02-14 N-(2-Morpholinoäthyl)-Benzamidderivate, deren Säureadditionssalze, Verfahren zu deren Herstellung und pharmazeutisches Präparat
MC771233A MC1136A1 (fr) 1976-02-16 1977-02-14 Benzamides
ES455907A ES455907A1 (es) 1976-02-16 1977-02-15 Un procedimiento para la preparacion de derivados de benza- mida.
NO770488A NO148417C (no) 1976-02-16 1977-02-15 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive benzamider
GR52790A GR62413B (en) 1976-02-16 1977-02-15 Preparation process of benzamides
BE174926A BE851422A (fr) 1976-02-16 1977-02-15 Benzamides
SE7701669A SE426822B (sv) 1976-02-16 1977-02-15 Forfarande for framstellning av n-morfolinoetylbensamider
PT66195A PT66195B (fr) 1976-02-16 1977-02-15 Procede pour la preparation des derives de benzamides
GB6215/77A GB1512194A (en) 1976-02-16 1977-02-15 Benzamides
AR268800A AR212554A1 (es) 1976-02-16 1977-08-15 Procedimiento para la obtencion de n-(2 morfolinoetil)-benzamidas
AT25678A AT349480B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholin- derivaten, ihren n-oxiden und salzen
AT25778A AT349481B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxiden und salzen
AT25578A AT349479B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholin- derivaten, ihren n-oxiden und salzen
AT25878A AT349482B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxiden und salzen
ES467448A ES467448A1 (es) 1976-02-16 1978-03-01 Un procedimiento para la preparacion de derivados de benza- mida.
ES467455A ES467455A1 (es) 1976-02-16 1978-03-01 Un procedimiento para la preparacion de derivados de benza- mida.
ES467449A ES467449A1 (es) 1976-02-16 1978-03-01 Un procedimiento para la preparacion de derivados de benza- mida.
CH554580A CH623576A5 (en) 1976-02-16 1980-07-18 Process for the preparation of benzamides
CH554480A CH622787A5 (en) 1976-02-16 1980-07-18 Process for the preparation of benzamides
CH554380A CH622786A5 (en) 1976-02-16 1980-07-18 Process for the preparation of benzamides
CH554680A CH623577A5 (en) 1976-02-16 1980-07-18 Process for the preparation of benzamides
HRP-60/77A HRP930495B1 (en) 1976-02-16 1993-03-24 Process for the preparation of new benzamides
LU88300C LU88300I2 (de) 1976-02-16 1993-06-10 Moclobemide (Aurorix)
NL930082C NL930082I2 (nl) 1976-02-16 1993-06-17 Werkwijze voor het bereiden van geneesmiddelen op basis van een in de fenylgroep gesubstitueerd N-(2morfolinoëthyl)-benzamide en werkwijze voor het bereiden van deze benzamiden.
NO1994008C NO1994008I1 (no) 1976-02-16 1994-08-03 Moklobemid/ 4-klor-N-(2-(4-morfolinyl)-etyl)benzamid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT107076A AT345842B (de) 1976-02-16 1976-02-16 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxyden und salzen

Publications (2)

Publication Number Publication Date
ATA107076A ATA107076A (de) 1978-02-15
AT345842B true AT345842B (de) 1978-10-10

Family

ID=3505951

Family Applications (5)

Application Number Title Priority Date Filing Date
AT107076A AT345842B (de) 1976-02-16 1976-02-16 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxyden und salzen
AT25778A AT349481B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxiden und salzen
AT25878A AT349482B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxiden und salzen
AT25578A AT349479B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholin- derivaten, ihren n-oxiden und salzen
AT25678A AT349480B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholin- derivaten, ihren n-oxiden und salzen

Family Applications After (4)

Application Number Title Priority Date Filing Date
AT25778A AT349481B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxiden und salzen
AT25878A AT349482B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholinderivaten, ihren n-oxiden und salzen
AT25578A AT349479B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholin- derivaten, ihren n-oxiden und salzen
AT25678A AT349480B (de) 1976-02-16 1978-01-13 Verfahren zur herstellung von neuen morpholin- derivaten, ihren n-oxiden und salzen

Country Status (28)

Country Link
JP (1) JPS52100476A (fr)
AR (2) AR214307A1 (fr)
AT (5) AT345842B (fr)
AU (1) AU506427B2 (fr)
BE (1) BE851422A (fr)
CA (1) CA1076112A (fr)
CH (5) CH623317A5 (fr)
DE (1) DE2706179C2 (fr)
DK (1) DK148824C (fr)
ES (4) ES455907A1 (fr)
FI (1) FI65426C (fr)
FR (1) FR2340940A1 (fr)
GB (1) GB1512194A (fr)
GR (1) GR62413B (fr)
HR (1) HRP930495B1 (fr)
IE (1) IE44482B1 (fr)
IL (1) IL51406A (fr)
LU (2) LU76771A1 (fr)
MC (1) MC1136A1 (fr)
NL (2) NL179382C (fr)
NO (2) NO148417C (fr)
NZ (1) NZ183316A (fr)
PH (1) PH12847A (fr)
PT (1) PT66195B (fr)
SE (1) SE426822B (fr)
SI (1) SI7710060A8 (fr)
YU (1) YU39983B (fr)
ZA (1) ZA77746B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005263787A (ja) * 2004-02-17 2005-09-29 Ishihara Sangyo Kaisha Ltd アミド系化合物又はその塩、並びにそれらを含有するサイトカイン産生抑制剤
ATE414694T1 (de) 2005-05-03 2008-12-15 Bayer Cropscience Sa Neue heterocyclylethylbenzamid-derivate
RU2570898C2 (ru) * 2014-03-27 2015-12-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский химико-технологический университет имени Д.И. Менделеева (РХТУ им. Д.И. Менделеева)" Способ получения n-[2-(морфолин-4-ил)этил]-4-хлорбензамида (варианты)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH451142A (de) * 1965-01-19 1968-05-15 Sandoz Ag Verfahren zur Herstellung neuer basisch substituierter Benzoesäureamide
FR1501846A (fr) * 1966-09-26 1967-11-18 Bellon Labor Sa Roger Procédé amélioré pour la préparation des thioamides
US3787419A (en) * 1971-07-01 1974-01-22 American Home Prod N-substituted-alpha,alpha,alpha-trifluoro-m-toluamides

Also Published As

Publication number Publication date
ES467455A1 (es) 1978-10-16
DK148824B (da) 1985-10-14
IL51406A0 (en) 1977-04-29
NL179382C (nl) 1986-09-01
SE7701669L (sv) 1977-08-17
NZ183316A (en) 1979-04-26
ATA25878A (de) 1978-09-15
YU6077A (en) 1983-01-21
MC1136A1 (fr) 1977-11-18
ES467448A1 (es) 1978-10-16
GR62413B (en) 1979-04-11
IL51406A (en) 1979-12-30
NO148417B (no) 1983-06-27
IE44482L (en) 1977-08-16
FI65426B (fi) 1984-01-31
GB1512194A (en) 1978-05-24
ATA25778A (de) 1978-09-15
AR214307A1 (es) 1979-05-31
JPS52100476A (en) 1977-08-23
AT349479B (de) 1979-04-10
PT66195A (fr) 1977-03-01
LU76771A1 (fr) 1978-04-13
ATA25678A (de) 1978-09-15
JPS6215547B2 (fr) 1987-04-08
AT349482B (de) 1979-04-10
NO770488L (no) 1977-08-17
DK148824C (da) 1986-04-21
AT349480B (de) 1979-04-10
CH623576A5 (en) 1981-06-15
BE851422A (fr) 1977-08-16
ZA77746B (en) 1977-12-28
CH623317A5 (en) 1981-05-29
CA1076112A (fr) 1980-04-22
PH12847A (en) 1979-09-12
ES455907A1 (es) 1978-05-01
YU39983B (en) 1985-06-30
ATA25578A (de) 1978-09-15
NL930082I2 (nl) 1994-08-16
CH622786A5 (en) 1981-04-30
AU2109977A (en) 1978-07-13
DE2706179A1 (de) 1977-08-18
ATA107076A (de) 1978-02-15
DK51677A (da) 1977-08-17
HRP930495B1 (en) 1996-10-31
LU88300I2 (de) 1994-09-09
FI770356A (fr) 1977-08-17
SE426822B (sv) 1983-02-14
DE2706179C2 (de) 1984-02-02
NL179382B (nl) 1986-04-01
CH622787A5 (en) 1981-04-30
AT349481B (de) 1979-04-10
AU506427B2 (en) 1980-01-03
NO1994008I1 (no) 1994-08-03
CH623577A5 (en) 1981-06-15
NO148417C (no) 1983-10-12
FI65426C (fi) 1984-05-10
AR212554A1 (es) 1978-07-31
PT66195B (fr) 1979-01-17
ES467449A1 (es) 1978-10-16
NL930082I1 (nl) 1993-09-16
NL7701144A (nl) 1977-08-18
FR2340940A1 (fr) 1977-09-09
FR2340940B1 (fr) 1981-01-09
SI7710060A8 (en) 1996-12-31
IE44482B1 (en) 1981-12-16

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UEP Publication of translation of european patent specification
SZA Application filed for a certificate of protection

Free format text: SZ123/94, 941222

EZF Grant of a certificate of protection

Free format text: SZ123/94, 941222

ELA Expired due to lapse of time
REN Ceased due to non-payment of the annual fee