AT276640B - Verfahren zur Herstellung von neuen N<6>-Aralkyl-adenosin-derivaten - Google Patents

Verfahren zur Herstellung von neuen N<6>-Aralkyl-adenosin-derivaten

Info

Publication number
AT276640B
AT276640B AT1110667A AT1110667A AT276640B AT 276640 B AT276640 B AT 276640B AT 1110667 A AT1110667 A AT 1110667A AT 1110667 A AT1110667 A AT 1110667A AT 276640 B AT276640 B AT 276640B
Authority
AT
Austria
Prior art keywords
aralkyl
preparation
new
adenosine derivatives
adenosine
Prior art date
Application number
AT1110667A
Other languages
English (en)
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Application granted granted Critical
Publication of AT276640B publication Critical patent/AT276640B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT1110667A 1966-12-09 1967-12-07 Verfahren zur Herstellung von neuen N<6>-Aralkyl-adenosin-derivaten AT276640B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEB0090219 1966-12-09
DEB0093416 1967-07-11

Publications (1)

Publication Number Publication Date
AT276640B true AT276640B (de) 1969-11-25

Family

ID=25968244

Family Applications (2)

Application Number Title Priority Date Filing Date
AT06861/68A AT277475B (de) 1966-12-09 1967-12-07 Verfahren zur herstellung von neuen n6-aralkyl-adenosinderivaten
AT1110667A AT276640B (de) 1966-12-09 1967-12-07 Verfahren zur Herstellung von neuen N<6>-Aralkyl-adenosin-derivaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT06861/68A AT277475B (de) 1966-12-09 1967-12-07 Verfahren zur herstellung von neuen n6-aralkyl-adenosinderivaten

Country Status (8)

Country Link
US (1) US3506643A (de)
AT (2) AT277475B (de)
CH (2) CH491119A (de)
FI (1) FI49302C (de)
FR (2) FR1550512A (de)
GB (1) GB1145789A (de)
NL (1) NL130339C (de)
SE (1) SE323383B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2007273A1 (de) * 1970-02-18 1971-08-26 Boehnnger Mannheim GmbH, 6800 Mann heim Waldhof N(6) Aralkyl adenosin Derivate und Verfahren zur Herstellung derselben
DE2244328A1 (de) * 1972-09-09 1974-03-21 Boehringer Mannheim Gmbh Neue n(6)-disubstituierte adenosinderivate und verfahren zur herstellung derselben
US4514405A (en) * 1981-09-17 1985-04-30 Merck Patent Gesellschaft Mit Beschrankter Haftung Use of adenosine derivatives as anticonvulsants
US5284834A (en) * 1985-03-29 1994-02-08 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Adenosine functionalized congeners as cardiovascular treating agents for animals and methods for using same
JPS63208525A (ja) * 1987-02-25 1988-08-30 Kikkoman Corp 心不全治療剤
AU4772493A (en) * 1992-07-15 1994-02-14 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Sulfo-derivatives of adenosine
JP2003519232A (ja) * 2000-01-07 2003-06-17 ウニフェルジテーレ・インステリング・アントウェルペン プリン誘導体、その製造法およびその使用
CZ294538B6 (cs) * 2002-12-30 2005-01-12 Ústav Experimentální Botaniky Akademie Vědčeské Re Substituční deriváty N6-benzyladenosinu, způsob jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
US20070161582A1 (en) * 2003-08-08 2007-07-12 Dusan Mijikovic Pharmaceutical compositions and methods for metabolic modulation
RS53494B9 (sr) 2009-06-29 2020-11-30 Incyte Holdings Corp Pirimidinoni kao inhibitori pi3k
US8759359B2 (en) 2009-12-18 2014-06-24 Incyte Corporation Substituted heteroaryl fused derivatives as PI3K inhibitors
TW201130842A (en) * 2009-12-18 2011-09-16 Incyte Corp Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors
AR081823A1 (es) 2010-04-14 2012-10-24 Incyte Corp DERIVADOS FUSIONADOS COMO INHIBIDORES DE PI3Kd
US9062055B2 (en) 2010-06-21 2015-06-23 Incyte Corporation Fused pyrrole derivatives as PI3K inhibitors
CA2822070C (en) 2010-12-20 2019-09-17 Incyte Corporation N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
US9108984B2 (en) 2011-03-14 2015-08-18 Incyte Corporation Substituted diamino-pyrimidine and diamino-pyridine derivatives as PI3K inhibitors
WO2012135009A1 (en) 2011-03-25 2012-10-04 Incyte Corporation Pyrimidine-4,6-diamine derivatives as pi3k inhibitors
BR122019020716B1 (pt) 2011-09-02 2021-02-17 Incyte Holdings Corporation heterociclilaminas como inibidores de pi3k e composição farmacêutica que as compreende
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
WO2015191677A1 (en) 2014-06-11 2015-12-17 Incyte Corporation Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
EP3262046B1 (de) 2015-02-27 2020-11-04 Incyte Corporation Pi3k-hemmer-salze und verfahren zu ihrer herstellung
WO2016183063A1 (en) 2015-05-11 2016-11-17 Incyte Corporation Crystalline forms of a pi3k inhibitor
US9732097B2 (en) 2015-05-11 2017-08-15 Incyte Corporation Process for the synthesis of a phosphoinositide 3-kinase inhibitor
MX2020012826A (es) 2018-06-01 2021-03-09 Incyte Corp Regimen de dosificacion para el tratamiento de trastornos relacionados con fosfatidilinositol 3-cinasas (pi3k).

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3014900A (en) * 1959-01-26 1961-12-26 Upjohn Co Process for the preparation of ketosidopurines

Also Published As

Publication number Publication date
AT277475B (de) 1969-12-29
SE323383B (de) 1970-05-04
FI49302C (fi) 1975-05-12
FI49302B (de) 1975-01-31
CH509326A (de) 1971-06-30
FR1550512A (de) 1968-12-20
FR7285M (de) 1969-09-22
CH491119A (de) 1970-05-31
NL130339C (de) 1970-12-15
NL6716737A (de) 1968-06-10
GB1145789A (en) 1969-03-19
US3506643A (en) 1970-04-14

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