AT249277B - Verfahren zur Herstellung neuer Benzomorphane - Google Patents
Verfahren zur Herstellung neuer BenzomorphaneInfo
- Publication number
- AT249277B AT249277B AT392965A AT392965A AT249277B AT 249277 B AT249277 B AT 249277B AT 392965 A AT392965 A AT 392965A AT 392965 A AT392965 A AT 392965A AT 249277 B AT249277 B AT 249277B
- Authority
- AT
- Austria
- Prior art keywords
- benzomorphans
- new
- production
- new benzomorphans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Discharge Lamp (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT249277B true AT249277B (de) | 1966-09-12 |
Family
ID=23297612
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT1074364A AT253687B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung von neuen Benzomorphanen |
| AT392865A AT249276B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung neuer Benzomorphane |
| AT1074264A AT261126B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung von neuen Benzomorphanen |
| AT392965A AT249277B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung neuer Benzomorphane |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT1074364A AT253687B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung von neuen Benzomorphanen |
| AT392865A AT249276B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung neuer Benzomorphane |
| AT1074264A AT261126B (de) | 1963-12-20 | 1964-12-18 | Verfahren zur Herstellung von neuen Benzomorphanen |
Country Status (12)
| Country | Link |
|---|---|
| AT (4) | AT253687B (en:Method) |
| BE (2) | BE657406A (en:Method) |
| CH (7) | CH449641A (en:Method) |
| DE (2) | DE1445853A1 (en:Method) |
| DK (4) | DK108497C (en:Method) |
| ES (4) | ES307299A1 (en:Method) |
| FR (2) | FR4345M (en:Method) |
| GB (2) | GB1077711A (en:Method) |
| IL (2) | IL22643A (en:Method) |
| NL (3) | NL6414820A (en:Method) |
| NO (2) | NO119273B (en:Method) |
| SE (2) | SE305657B (en:Method) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| EP2987788A1 (en) | 2002-05-17 | 2016-02-24 | Taiwanj Pharmaceuticals Co., Ltd. | Opioid and opioid-like compounds and uses thereof |
| US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| WO2008106128A2 (en) | 2007-02-26 | 2008-09-04 | Vitae Pharmaceuticals, Inc. | CYCLIC UREA AND CARBAMATE INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1 |
| WO2009017664A1 (en) | 2007-07-26 | 2009-02-05 | Vitae Pharmaceuticals, Inc. | CYCLIC INHIBITORS OF 11β-HYDROXYSTERIOD DEHYDROGENASE 1 |
| AR069207A1 (es) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
| AR069545A1 (es) | 2007-11-16 | 2010-02-03 | Boehringer Ingelheim Pharma | Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y |
| US8440658B2 (en) | 2007-12-11 | 2013-05-14 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| EP2252601B1 (en) | 2008-01-24 | 2012-12-19 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| CA2714532A1 (en) | 2008-02-11 | 2009-08-20 | Vitae Pharmaceuticals, Inc. | 1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| EP2245014B1 (en) * | 2008-02-12 | 2011-11-02 | Boehringer Ingelheim International GmbH | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| JP5730021B2 (ja) | 2008-02-15 | 2015-06-03 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体 |
| JP5538365B2 (ja) | 2008-05-01 | 2014-07-02 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 |
| US8138178B2 (en) | 2008-05-01 | 2012-03-20 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8242111B2 (en) | 2008-05-01 | 2012-08-14 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| JP5696037B2 (ja) | 2008-05-01 | 2015-04-08 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター |
| CL2009001151A1 (es) | 2008-05-13 | 2010-08-13 | Boehringer Ingelheim Int | Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos. |
| EP2324017B1 (en) | 2008-07-25 | 2014-12-31 | Boehringer Ingelheim International GmbH | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 |
| PE20110566A1 (es) | 2008-07-25 | 2011-09-02 | Boehringer Ingelheim Int | Inhibidores ciclicos de 11beta-hidroxiesteroide deshidrogenasa 1 |
| AR073920A1 (es) | 2008-10-23 | 2010-12-09 | Boehringer Ingelheim Int | Derivados urea de nortropanos sustituidos, medicamentos que contienen dichos compuestos , su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa y proceso para su preparacion. |
| JP5679997B2 (ja) | 2009-02-04 | 2015-03-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 |
| UA109255C2 (ru) | 2009-04-30 | 2015-08-10 | Берінгер Інгельхайм Інтернешнл Гмбх | Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1 |
| WO2010139673A1 (en) | 2009-06-02 | 2010-12-09 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
| JP5749263B2 (ja) | 2009-07-01 | 2015-07-15 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター |
| TWI531571B (zh) | 2009-11-06 | 2016-05-01 | 維它藥物公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物 |
| WO2011159760A1 (en) | 2010-06-16 | 2011-12-22 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| JP5813106B2 (ja) | 2010-06-25 | 2015-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 代謝障害の処置のための１１−β−ＨＳＤ１のインヒビターとしてのアザスピロヘキサノン |
| KR20130137628A (ko) | 2010-11-02 | 2013-12-17 | 베링거 인겔하임 인터내셔날 게엠베하 | 대사 장애를 치료하기 위한 약제학적 병용물 |
| TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物 |
| EP2744783A1 (en) | 2011-08-17 | 2014-06-25 | Boehringer Ingelheim International GmbH | Indenopyridine derivatives |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1618967A patent/CH449641A/de unknown
- 1964-11-30 CH CH1618767A patent/CH449639A/de unknown
- 1964-11-30 CH CH1618867A patent/CH449640A/de unknown
- 1964-11-30 CH CH1619067A patent/CH449642A/de unknown
- 1964-11-30 CH CH1538464A patent/CH446371A/de unknown
- 1964-11-30 CH CH1619167A patent/CH449643A/de unknown
- 1964-11-30 CH CH1538364A patent/CH448118A/de unknown
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 AT AT1074364A patent/AT253687B/de active
- 1964-12-18 AT AT392865A patent/AT249276B/de active
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/de active Pending
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/de active Pending
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-18 AT AT1074264A patent/AT261126B/de active
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-18 AT AT392965A patent/AT249277B/de active
- 1964-12-18 IL IL2264364A patent/IL22643A/xx unknown
- 1964-12-18 IL IL2264264A patent/IL22642A/xx unknown
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-19 DK DK429865A patent/DK108497C/da active
- 1964-12-19 DK DK429765A patent/DK108496C/da active
- 1964-12-19 ES ES0307299A patent/ES307299A1/es not_active Expired
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-19 ES ES0307300A patent/ES307300A1/es not_active Expired
- 1964-12-19 DK DK626764A patent/DK108495C/da active
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-19 DK DK626864A patent/DK106552C/da active
- 1964-12-19 ES ES0307302A patent/ES307302A1/es not_active Expired
- 1964-12-19 ES ES0307301A patent/ES307301A1/es not_active Expired
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
-
1965
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
Also Published As
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