AT136142B - Radiological procedure. - Google Patents

Radiological procedure.

Info

Publication number
AT136142B
AT136142B AT136142DA AT136142B AT 136142 B AT136142 B AT 136142B AT 136142D A AT136142D A AT 136142DA AT 136142 B AT136142 B AT 136142B
Authority
AT
Austria
Prior art keywords
acid
salts
iodomethanesulfonic
aliphatic
substituted
Prior art date
Application number
Other languages
German (de)
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Application granted granted Critical
Publication of AT136142B publication Critical patent/AT136142B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0495—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound intended for oral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Description

  

   <Desc/Clms Page number 1> 
 
 EMI1.1 
 



   Durch das Patent Nr. 128587 und sein Zusatzpatent Nr. 134007 wird ein röntgenologisehes Verfahren   geschützt.   Es besteht darin, dass man zum   röntgenographischen   Sichtbarmachen von Hohlsystemen des   Warmblüteorganismus   die Salze der Jodmethansulfosäure bzw. der durch aliphatische oder alizyklische Reste substituierten Jodmethansulfosäure verwendet. 



   Bei der weiteren Bearbeitung wurde gefunden, dass ausser den Salzen der Jodmethansulfosäure bzw. ihrer obengenannten Substitutionsprodukte auch die Salze der ein weiteres Jodatom tragenden   Dijodmethansulfosäure   bzw. der ein weiteres Jodatom tragenden, durch aliphatische oder alizyklische Reste substituierten Jodmethansulfosäure in hervorragender Weise zur röntgenographischen Darstellung von Hohlsystemen des Warmblüteorganismus geeignet und in der in den älteren Patenten beschriebenen Weise anwendbar sind. 



   Beispiel : Einem durch entsprechende Diät vorbereiteten Menschen werden 15 g des Natriumsalzes der Dijodmethansulfosäure, in 100 cm3 Wasser gelöst, innerhalb 1-2 Minuten intravenös injiziert. Wenige Minuten später wird in üblicher Weise eine Röntgenaufnahme hergestellt, die ein naturgetreues Bild der Harnwege liefert. 



   Zum gleichen Ergebnis gelangt man, wenn man an Stelle des Salzes der Dijodmethansulfosäure Salze der ein weiteres Jodatom tragenden, durch aliphatische oder alizyklische Reste substituierten Jodmethansulfosäure verwendet. Als solche Säure sei beispielsweise   die &alpha;-&alpha;-Dijodäthansulfosäure genannt   mit dem Natriumsalz von der Formel CH3. CJ2.   S03Na.   

**WARNUNG** Ende DESC Feld kannt Anfang CLMS uberlappen**.



   <Desc / Clms Page number 1>
 
 EMI1.1
 



   A radiological method is protected by patent no. 128587 and its additional patent no. 134007. It consists in using the salts of iodomethanesulfonic acid or the iodomethanesulfonic acid substituted by aliphatic or alicyclic radicals for the radiographic visualization of hollow systems of the warm-blooded organism.



   In further processing it was found that, in addition to the salts of iodomethanesulfonic acid or its above-mentioned substitution products, the salts of diiodomethanesulfonic acid bearing an additional iodine atom or of the iodomethanesulfonic acid bearing an additional iodine atom and substituted by aliphatic or alicyclic radicals are excellent for the X-ray representation of hollow systems of the warm-blooded organism and are applicable in the manner described in the earlier patents.



   Example: 15 g of the sodium salt of diiodomethanesulfonic acid, dissolved in 100 cm3 of water, are injected intravenously within 1-2 minutes into a person who has been prepared by an appropriate diet. A few minutes later, an X-ray is taken in the usual way, which provides a natural picture of the urinary tract.



   The same result is obtained if, in place of the salt of diiodomethanesulfonic acid, salts of the iodomethanesulfonic acid which has another iodine atom and which are substituted by aliphatic or alicyclic radicals are used. Such an acid is, for example, the α-α-diiodoethanesulfonic acid with the sodium salt of the formula CH3. CJ2. S03Na.

** WARNING ** End of DESC field may overlap beginning of CLMS **.

Claims (1)

PATENT-ANSPRUCH : Röntgenologisches Verfahren, dadurch gekennzeichnet, dass zum Sichtbarmachen von Hohlsystemen des Warmblüteorganismus die Salze der Dijodmethansulfosäure bzw. der ein weiteres Jodatom tragenden, durch aliphatische oder alizyldische Reste substituierten Jodmethansulfosäure verwendet werden. **WARNUNG** Ende CLMS Feld Kannt Anfang DESC uberlappen**. PATENT CLAIM: X-ray method, characterized in that the salts of diiodomethanesulfonic acid or of the iodomethanesulfonic acid which carries a further iodine atom and substituted by aliphatic or alicyclic radicals are used to make hollow systems of the warm-blooded organism visible. ** WARNING ** End of CLMS field may overlap beginning of DESC **.
AT136142D 1930-07-08 1931-07-01 Radiological procedure. AT136142B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE652594T 1930-07-08

Publications (1)

Publication Number Publication Date
AT136142B true AT136142B (en) 1934-01-10

Family

ID=6581711

Family Applications (1)

Application Number Title Priority Date Filing Date
AT136142D AT136142B (en) 1930-07-08 1931-07-01 Radiological procedure.

Country Status (2)

Country Link
AT (1) AT136142B (en)
DE (1) DE652594C (en)

Also Published As

Publication number Publication date
DE652594C (en) 1937-11-03

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