AR245958A1 - Procedimiento para la preparacion de polipeptidos de interleucina-1alfa - Google Patents

Procedimiento para la preparacion de polipeptidos de interleucina-1alfa

Info

Publication number
AR245958A1
AR245958A1 AR89312971A AR31297189A AR245958A1 AR 245958 A1 AR245958 A1 AR 245958A1 AR 89312971 A AR89312971 A AR 89312971A AR 31297189 A AR31297189 A AR 31297189A AR 245958 A1 AR245958 A1 AR 245958A1
Authority
AR
Argentina
Prior art keywords
recombinant human
human interleukin
alpha polypeptides
recombinant
interleukin
Prior art date
Application number
AR89312971A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of AR245958A1 publication Critical patent/AR245958A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE POLIPEPTIDOS DE INTERLEUCINA-1ALFA HUMANA RECOMBINANTE HOMOGENEA QUE COMPRENDE LA SECUENCIA DE AMINOACIDOS SELECCIONADA ENTRE I O BIEN II QUE COMPRENDE: A)CULTIVAR UN ORGANISMO UNICELULAR TRANSFORMADO, QUE ES UNA CELULA BACTERIANA E. COLI, CON UN VECTOR RECOMBIANTE QUE ES UN PLASMIDO RECOMBINANTE QUE CONTIENE UN DNA QUE CODIFICA DICHO POLIPEPTIDO EN UN MEDIO DE CULTIVO; Y B) SEPARAR EL POLIPEPTIDO DE INTERLEUCINA-1 HUMANA DEL CULTIVO Y PURIFICAR HASTA HOMOGENEIDAD.
AR89312971A 1988-01-15 1989-01-12 Procedimiento para la preparacion de polipeptidos de interleucina-1alfa AR245958A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14445788A 1988-01-15 1988-01-15

Publications (1)

Publication Number Publication Date
AR245958A1 true AR245958A1 (es) 1994-03-30

Family

ID=22508674

Family Applications (1)

Application Number Title Priority Date Filing Date
AR89312971A AR245958A1 (es) 1988-01-15 1989-01-12 Procedimiento para la preparacion de polipeptidos de interleucina-1alfa

Country Status (19)

Country Link
EP (1) EP0324447B1 (es)
JP (1) JP2567079B2 (es)
AR (1) AR245958A1 (es)
AT (1) ATE142696T1 (es)
AU (1) AU616461B2 (es)
DE (1) DE58909723D1 (es)
DK (1) DK16489A (es)
ES (1) ES2091752T3 (es)
FI (1) FI890175A (es)
GR (1) GR3021887T3 (es)
HU (1) HU208996B (es)
IE (1) IE890087L (es)
IL (1) IL88934A (es)
MC (1) MC2002A1 (es)
NO (1) NO890174L (es)
NZ (1) NZ227594A (es)
PT (1) PT89438B (es)
YU (1) YU6889A (es)
ZA (1) ZA89202B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0188920B1 (en) * 1984-12-25 1993-09-29 Dainippon Pharmaceutical Co., Ltd. Interleukin 1 and its derivative
DE3818660A1 (de) * 1987-06-05 1988-12-15 Colgate Palmolive Co Freifliessendes, pulvriges geschirrwaschmittel und verfahren zur herstellung desselben
KR960008010B1 (ko) * 1988-07-29 1996-06-19 오오쓰까세이야꾸 가부시끼가이샤 IL-1α 유도체 및 혈소판 감소증 치료 약제
US7176179B1 (en) 1997-05-30 2007-02-13 The Regents Of The University Of California Selective induction of cell death by delivery of amino-terminal interleukin-1-α pro-piece polypeptide
US6191269B1 (en) * 1997-05-30 2001-02-20 The Regents Of The University Of California Selective induction of cell death by delivery of amino-terminal interleukin-1-α pro-piece polypeptide
US20030154504A1 (en) 1998-06-24 2003-08-14 Farese Robert V. Methods and compositions for modulating carbohydrate metabolism
DE10252634A1 (de) * 2002-11-11 2004-05-27 Umwelttechnik Georg Fritzmeier Gmbh & Co. Reinigungsmittel und Verfahren zu seiner Herstellung
JP5661777B2 (ja) * 2009-09-29 2015-01-28 ユナイテッド・テクノロジーズ・ユーティー・アクチェンゲゼルシャフト 組換え型ヒトインターロイキン−１を含む口腔ケア組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0188920B1 (en) * 1984-12-25 1993-09-29 Dainippon Pharmaceutical Co., Ltd. Interleukin 1 and its derivative
EP0200986B2 (en) * 1985-04-25 1998-03-11 F. Hoffmann-La Roche Ag Recombinant human interleukin-1
DE3515217A1 (de) * 1985-04-26 1986-10-30 Siemens AG, 1000 Berlin und 8000 München Vorrichtung zur messung schwacher magnetfelder
US5017692A (en) * 1986-09-04 1991-05-21 Schering Corporation Truncated human interleukin-a alpha

Also Published As

Publication number Publication date
NO890174D0 (no) 1989-01-13
IL88934A0 (en) 1989-08-15
DK16489A (da) 1989-07-16
DK16489D0 (da) 1989-01-13
IL88934A (en) 1994-05-30
NZ227594A (en) 1991-09-25
ATE142696T1 (de) 1996-09-15
ES2091752T3 (es) 1996-11-16
GR3021887T3 (en) 1997-03-31
NO890174L (no) 1989-07-17
ZA89202B (en) 1989-09-27
FI890175A0 (fi) 1989-01-13
EP0324447B1 (de) 1996-09-11
DE58909723D1 (de) 1996-10-17
HUT50505A (en) 1990-02-28
EP0324447A2 (de) 1989-07-19
JPH025892A (ja) 1990-01-10
YU6889A (en) 1990-08-31
FI890175A (fi) 1989-07-16
PT89438A (pt) 1990-02-08
PT89438B (pt) 1993-09-30
JP2567079B2 (ja) 1996-12-25
HU208996B (en) 1994-09-28
IE890087L (en) 1989-07-15
EP0324447A3 (de) 1990-01-31
MC2002A1 (fr) 1990-01-26
AU2850989A (en) 1989-07-20
AU616461B2 (en) 1991-10-31

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