DK0458959T3 - Hidtil ukendte blodpladeafledte vækstfaktor B-kædeanaloger og fremgangsmåde til homogen fremstilling deraf - Google Patents

Hidtil ukendte blodpladeafledte vækstfaktor B-kædeanaloger og fremgangsmåde til homogen fremstilling deraf

Info

Publication number
DK0458959T3
DK0458959T3 DK91902366.3T DK91902366T DK0458959T3 DK 0458959 T3 DK0458959 T3 DK 0458959T3 DK 91902366 T DK91902366 T DK 91902366T DK 0458959 T3 DK0458959 T3 DK 0458959T3
Authority
DK
Denmark
Prior art keywords
analogs
pdgf
present
growth factor
novel
Prior art date
Application number
DK91902366.3T
Other languages
English (en)
Inventor
Arlen Read Thomason
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/454,794 external-priority patent/US5149792A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of DK0458959T3 publication Critical patent/DK0458959T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DK91902366.3T 1989-12-19 1990-12-17 Hidtil ukendte blodpladeafledte vækstfaktor B-kædeanaloger og fremgangsmåde til homogen fremstilling deraf DK0458959T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/454,794 US5149792A (en) 1989-12-19 1989-12-19 Platelet-derived growth factor B chain analogs
US07/624,451 US5272064A (en) 1989-12-19 1990-12-13 DNA molecules encoding platelet-derived growth factor B chain analogs and method for expression thereof

Publications (1)

Publication Number Publication Date
DK0458959T3 true DK0458959T3 (da) 1995-08-14

Family

ID=27037609

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91902366.3T DK0458959T3 (da) 1989-12-19 1990-12-17 Hidtil ukendte blodpladeafledte vækstfaktor B-kædeanaloger og fremgangsmåde til homogen fremstilling deraf

Country Status (17)

Country Link
US (1) US5272064A (da)
EP (1) EP0458959B1 (da)
JP (1) JPH04504064A (da)
AT (1) ATE123949T1 (da)
AU (1) AU646014B2 (da)
CA (1) CA2032675A1 (da)
DE (1) DE69020335T2 (da)
DK (1) DK0458959T3 (da)
ES (1) ES2073735T3 (da)
FI (1) FI913892A0 (da)
GR (1) GR3017317T3 (da)
IE (1) IE904608A1 (da)
IL (1) IL96723A0 (da)
NO (1) NO913232L (da)
NZ (1) NZ236549A (da)
PT (1) PT96272A (da)
WO (1) WO1991008761A1 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0639980A1 (en) * 1992-02-26 1995-03-01 Allergan, Inc. Use of platelet derived growth factor in ophthalmic wound healing
WO1993020204A1 (en) * 1992-03-30 1993-10-14 Schering Corporation Monomeric platelet-derived growth factor and prevention of stenosis or restenosis
AU2003220529B2 (en) 2002-03-27 2006-09-07 Immunex Corporation Methods for increasing polypeptide production
WO2004070018A2 (en) * 2003-02-04 2004-08-19 Ludwig Institute For Cancer Research Vegf-b and pdgf modulation of stem cells
BR112012000865A2 (pt) 2009-07-17 2019-09-24 T Tabor Aaron "composição e método para a modificação genética cosmética de células substancialmente intactas"
WO2012019160A1 (en) 2010-08-05 2012-02-09 Amgen Inc. Dipeptides to enhance yield and viability from cell cultures
CA3145238A1 (en) 2011-04-20 2012-10-26 Amgen Inc. Autoinjector apparatus
WO2012145682A1 (en) 2011-04-21 2012-10-26 Amgen Inc. A method for culturing mammalian cells to improve recombinant protein production
KR102558247B1 (ko) 2011-07-01 2023-07-24 암젠 인크 포유동물 세포 배양
JP2014529473A (ja) 2011-09-02 2014-11-13 アムジエン・インコーポレーテツド 医薬製品および医薬製品の露光を分析する方法
AR089231A1 (es) 2011-12-15 2014-08-06 Amgen Inc Metodo de floculacion
US20150353542A1 (en) 2013-01-14 2015-12-10 Amgen Inc. Methods of using cell-cycle inhibitors to modulate one or more properties of a cell culture
TWI625390B (zh) 2013-03-14 2018-06-01 安美基公司 用於增加重組蛋白質之甘露糖含量之方法
LT3395423T (lt) 2013-03-14 2023-12-11 Amgen Inc. Pratekančių giminingumo gryninimo ligandų pašalinimas
WO2014143815A2 (en) 2013-03-15 2014-09-18 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
EP2968760B1 (en) 2013-03-15 2024-01-03 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
TWI592183B (zh) 2013-03-15 2017-07-21 安美基公司 本體輪廓可調適之自動注射器裝置
US9481901B2 (en) 2013-05-30 2016-11-01 Amgen Inc. Methods for increasing mannose content of recombinant proteins
MX2016005572A (es) 2013-10-31 2016-12-09 Amgen Inc Uso de monensina para regular la glicosilacion de proteinas recombinantes.
US10513723B2 (en) 2014-01-13 2019-12-24 Amgen Inc. Decreasing ornithine production to decrease high mannose glycoform content of recombinant proteins
US10106829B2 (en) 2014-01-29 2018-10-23 Amgen Inc. Overexpression of N-glycosylation pathway regulators to modulate glycosylation of recombinant proteins
KR102519540B1 (ko) 2014-01-29 2023-04-10 암젠 인크 재조합 단백질의 글리코실화를 조절하기 위한 n-글리코실화 경로 조절자의 과발현
ES2909630T3 (es) 2014-06-04 2022-05-09 Amgen Inc Métodos de recolección en cultivos de células de mamífero
WO2016081770A1 (en) 2014-11-19 2016-05-26 Amgen Inc. Quantitation of glycan moiety in recombinant glycoproteins
ES2784503T3 (es) 2014-12-01 2020-09-28 Amgen Inc Procedimiento para manipular el nivel de contenido de glicano de una glicoproteína
AU2018368338B2 (en) 2017-11-16 2024-07-25 Amgen Inc. Autoinjector with stall and end point detection
KR20210005689A (ko) 2018-05-01 2021-01-14 암젠 인크 조절된 글리칸 프로파일을 갖는 항체
WO2023079058A1 (en) 2021-11-05 2023-05-11 Yokogawa Insilico Biotechnology Gmbh Cell culture with reduced production of lactate
WO2023129974A1 (en) 2021-12-29 2023-07-06 Bristol-Myers Squibb Company Generation of landing pad cell lines

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4479896A (en) * 1981-12-11 1984-10-30 Antoniades Harry N Method for extraction localization and direct recovery of platelet derived growth factor
EP0487116B1 (en) * 1984-10-12 1999-12-29 ZymoGenetics, Inc. Biologically active PDGF analogs in eucaryotic cells
US4766073A (en) * 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4769328A (en) * 1984-10-12 1988-09-06 Zymogenetics Inc. Expression of biologically active PDGF analogs in yeast
US4801542A (en) * 1984-10-12 1989-01-31 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
EP0259632B1 (en) * 1986-08-13 1995-12-13 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
DE3834079A1 (de) * 1988-10-06 1990-04-12 Biotechnolog Forschung Gmbh Wachstumstimulierendes pdgf-bb und dessen verwendung sowie ein verfahren zu seiner herstellung und der des monomeren
IL96682A0 (en) * 1989-12-15 1991-09-16 Amgen Inc Production of biologically active platelet-derived growth factor from high expression host cell systems

Also Published As

Publication number Publication date
EP0458959A4 (en) 1993-06-16
AU7153491A (en) 1991-07-18
EP0458959A1 (en) 1991-12-04
AU646014B2 (en) 1994-02-03
FI913892A0 (fi) 1991-08-16
NO913232D0 (no) 1991-08-19
NZ236549A (en) 1993-03-26
DE69020335T2 (de) 1995-11-02
ES2073735T3 (es) 1995-08-16
PT96272A (pt) 1991-09-30
CA2032675A1 (en) 1991-06-20
ATE123949T1 (de) 1995-07-15
EP0458959B1 (en) 1995-06-21
JPH04504064A (ja) 1992-07-23
NO913232L (no) 1991-08-19
WO1991008761A1 (en) 1991-06-27
DE69020335D1 (de) 1995-07-27
IE904608A1 (en) 1991-06-19
IL96723A0 (en) 1991-09-16
GR3017317T3 (en) 1995-12-31
US5272064A (en) 1993-12-21

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