AR122013A1 - Composiciones de virus adenoasociados compatibles entre especies y métodos para su uso - Google Patents
Composiciones de virus adenoasociados compatibles entre especies y métodos para su usoInfo
- Publication number
- AR122013A1 AR122013A1 ARP210101222A ARP210101222A AR122013A1 AR 122013 A1 AR122013 A1 AR 122013A1 AR P210101222 A ARP210101222 A AR P210101222A AR P210101222 A ARP210101222 A AR P210101222A AR 122013 A1 AR122013 A1 AR 122013A1
- Authority
- AR
- Argentina
- Prior art keywords
- methods
- adeno
- associated virus
- species
- compatible
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063020062P | 2020-05-05 | 2020-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR122013A1 true AR122013A1 (es) | 2022-08-03 |
Family
ID=78468375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP210101222A AR122013A1 (es) | 2020-05-05 | 2021-05-05 | Composiciones de virus adenoasociados compatibles entre especies y métodos para su uso |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US12577586B2 (enExample) |
| EP (1) | EP4125977A4 (enExample) |
| JP (1) | JP7756439B2 (enExample) |
| KR (1) | KR20230029616A (enExample) |
| CN (1) | CN116096377B (enExample) |
| AR (1) | AR122013A1 (enExample) |
| AU (1) | AU2021268946A1 (enExample) |
| BR (1) | BR112022022644A2 (enExample) |
| CA (1) | CA3177869A1 (enExample) |
| IL (1) | IL297577A (enExample) |
| MX (1) | MX2022013963A (enExample) |
| TW (1) | TWI910162B (enExample) |
| WO (1) | WO2021226267A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2022013963A (es) * | 2020-05-05 | 2023-02-22 | Univ Duke | Composiciones de virus adenoasociados compatibles entre especies y metodos de uso de las mismas. |
| EP4413147A4 (en) | 2021-10-08 | 2025-07-30 | Dyno Therapeutics Inc | CAPSID VARIANTS AND METHODS OF USE THEREOF |
| US20260055144A1 (en) * | 2022-08-24 | 2026-02-26 | Regenxbio Inc. | Recombinant adeno-associated viruses and uses thereof |
| WO2024168089A2 (en) * | 2023-02-07 | 2024-08-15 | Duke University | Compositions comprising aavs and methods for treating gastrointestinal diseases |
| TW202434734A (zh) * | 2023-02-08 | 2024-09-01 | 美商銀杏生物工作室有限公司 | 天使症候群的基因療法 |
| WO2024191778A1 (en) | 2023-03-10 | 2024-09-19 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2024206831A1 (en) * | 2023-03-31 | 2024-10-03 | Duke University | Compositions comprising brain-tropic aavs and methods of use thereof |
| AU2024332181A1 (en) | 2023-08-31 | 2026-02-12 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| WO2025250454A1 (en) * | 2024-05-28 | 2025-12-04 | University Of Rochester | Adeno-associated viruses evolved to specifically target human glial progenitor cells in vivo |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478745A (en) | 1992-12-04 | 1995-12-26 | University Of Pittsburgh | Recombinant viral vector system |
| ATE454445T1 (de) | 1998-11-10 | 2010-01-15 | Univ North Carolina | Virusvektoren und verfahren für ihre herstellung und verabreichung. |
| US7314912B1 (en) | 1999-06-21 | 2008-01-01 | Medigene Aktiengesellschaft | AAv scleroprotein, production and use thereof |
| ATE318923T1 (de) | 2000-06-01 | 2006-03-15 | Univ North Carolina | Doppelsträngige parvovirus-vektoren |
| HUE054805T2 (hu) | 2003-09-30 | 2021-09-28 | Univ Pennsylvania | Adeno-asszociált vírus (AAV) kládok, szekvenciák, az azokat tartalmazó vektorok és alkalmazásaik |
| US9198984B2 (en) | 2006-04-28 | 2015-12-01 | The Trustees Of The University Of Pennsylvania | Scalable production method for AAV |
| WO2010138263A2 (en) | 2009-05-28 | 2010-12-02 | University Of Massachusetts | Novel aav 's and uses thereof |
| US9409953B2 (en) * | 2011-02-10 | 2016-08-09 | The University Of North Carolina At Chapel Hill | Viral vectors with modified transduction profiles and methods of making and using the same |
| EP3470523A1 (en) | 2012-05-09 | 2019-04-17 | Oregon Health & Science University | Adeno associated virus plasmids and vectors |
| CN105247044B (zh) * | 2013-05-31 | 2021-05-07 | 加利福尼亚大学董事会 | 腺相关病毒变体及其使用方法 |
| US10746742B2 (en) * | 2014-04-25 | 2020-08-18 | Oregon Health & Science University | Methods of viral neutralizing antibody epitope mapping |
| US10577627B2 (en) | 2014-06-09 | 2020-03-03 | Voyager Therapeutics, Inc. | Chimeric capsids |
| IL314171A (en) * | 2015-09-28 | 2024-09-01 | Univ Florida | Methods and compositions for antibody-evading virus vectors |
| CA3052829A1 (en) | 2017-02-15 | 2018-08-23 | The University Of North Carolina At Chapel Hill | Methods and compositions for gene transfer across the vasculature |
| CN110650733A (zh) | 2017-02-28 | 2020-01-03 | 阿德夫拉姆生物技术股份有限公司 | 经过修饰的aav衣壳和其用途 |
| US11332727B2 (en) | 2017-03-14 | 2022-05-17 | The Regents Of The University Of California | Method for reducing an immune response by administering an immune evading adeno-associated AAV8 or AAVDJ viral vector |
| US10550405B2 (en) | 2017-03-15 | 2020-02-04 | The University Of North Carolina At Chapel Hill | Rational polyploid adeno-associated virus vectors and methods of making and using the same |
| IL316259A (en) | 2017-03-15 | 2024-12-01 | Univ North Carolina Chapel Hill | Polyploid gland associated with virus vectors and methods for preparing and using the same. |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| WO2019195444A1 (en) * | 2018-04-03 | 2019-10-10 | Stridebio, Inc. | Antibody-evading virus vectors |
| WO2019195423A1 (en) | 2018-04-03 | 2019-10-10 | Stridebio, Inc. | Virus vectors for targeting ophthalmic tissues |
| EP3793615A2 (en) | 2018-05-16 | 2021-03-24 | Voyager Therapeutics, Inc. | Directed evolution of aav to improve tropism for cns |
| BR112021006060A2 (pt) * | 2018-10-01 | 2021-07-20 | The Trustees Of The University Of Pennsylvania | composições úteis para tratamento de gangliosidose gm1 |
| AR118465A1 (es) | 2019-03-21 | 2021-10-06 | Stridebio Inc | Vectores de virus adenoasociados recombinantes |
| MX2022013963A (es) | 2020-05-05 | 2023-02-22 | Univ Duke | Composiciones de virus adenoasociados compatibles entre especies y metodos de uso de las mismas. |
-
2021
- 2021-05-05 MX MX2022013963A patent/MX2022013963A/es unknown
- 2021-05-05 BR BR112022022644A patent/BR112022022644A2/pt unknown
- 2021-05-05 KR KR1020227042650A patent/KR20230029616A/ko active Pending
- 2021-05-05 CA CA3177869A patent/CA3177869A1/en active Pending
- 2021-05-05 CN CN202180044147.9A patent/CN116096377B/zh active Active
- 2021-05-05 AR ARP210101222A patent/AR122013A1/es not_active Application Discontinuation
- 2021-05-05 EP EP21800135.2A patent/EP4125977A4/en active Pending
- 2021-05-05 JP JP2022567079A patent/JP7756439B2/ja active Active
- 2021-05-05 WO PCT/US2021/030937 patent/WO2021226267A2/en not_active Ceased
- 2021-05-05 TW TW110116293A patent/TWI910162B/zh active
- 2021-05-05 AU AU2021268946A patent/AU2021268946A1/en active Pending
- 2021-05-05 IL IL297577A patent/IL297577A/en unknown
- 2021-05-05 US US17/922,962 patent/US12577586B2/en active Active
-
2023
- 2023-09-26 US US18/474,506 patent/US12146151B2/en active Active
- 2023-09-26 US US18/474,533 patent/US12037598B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023524291A (ja) | 2023-06-09 |
| JP7756439B2 (ja) | 2025-10-20 |
| US12146151B2 (en) | 2024-11-19 |
| US12037598B2 (en) | 2024-07-16 |
| US20230151389A1 (en) | 2023-05-18 |
| KR20230029616A (ko) | 2023-03-03 |
| CA3177869A1 (en) | 2021-11-11 |
| CN116096377B (zh) | 2026-01-02 |
| WO2021226267A3 (en) | 2021-12-16 |
| CN116096377A (zh) | 2023-05-09 |
| US20240076695A1 (en) | 2024-03-07 |
| BR112022022644A2 (pt) | 2023-01-17 |
| WO2021226267A2 (en) | 2021-11-11 |
| IL297577A (en) | 2022-12-01 |
| US12577586B2 (en) | 2026-03-17 |
| AU2021268946A1 (en) | 2022-12-01 |
| TW202208631A (zh) | 2022-03-01 |
| MX2022013963A (es) | 2023-02-22 |
| TWI910162B (zh) | 2026-01-01 |
| EP4125977A2 (en) | 2023-02-08 |
| US20240067988A1 (en) | 2024-02-29 |
| EP4125977A4 (en) | 2024-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |