AR115411A2 - 8-[3-amino-piperidin-1-il]-xantinas como inhibidores de dpp-iv - Google Patents

8-[3-amino-piperidin-1-il]-xantinas como inhibidores de dpp-iv

Info

Publication number
AR115411A2
AR115411A2 ARP190101358A ARP190101358A AR115411A2 AR 115411 A2 AR115411 A2 AR 115411A2 AR P190101358 A ARP190101358 A AR P190101358A AR P190101358 A ARP190101358 A AR P190101358A AR 115411 A2 AR115411 A2 AR 115411A2
Authority
AR
Argentina
Prior art keywords
methyl
dpp
piperidin
amino
xanthines
Prior art date
Application number
ARP190101358A
Other languages
English (en)
Spanish (es)
Inventor
Leo Thomas
Mohammad Tadayyon
Matthias Eckhardt
Elke Langkopf
Frank Himmelsbach
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of AR115411A2 publication Critical patent/AR115411A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ARP190101358A 2004-02-18 2019-05-22 8-[3-amino-piperidin-1-il]-xantinas como inhibidores de dpp-iv AR115411A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004008112A DE102004008112A1 (de) 2004-02-18 2004-02-18 8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
AR115411A2 true AR115411A2 (es) 2021-01-13

Family

ID=34813493

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP190101358A AR115411A2 (es) 2004-02-18 2019-05-22 8-[3-amino-piperidin-1-il]-xantinas como inhibidores de dpp-iv

Country Status (5)

Country Link
CN (1) CN1980930B (zh)
AR (1) AR115411A2 (zh)
DE (1) DE102004008112A1 (zh)
UA (1) UA87835C2 (zh)
ZA (1) ZA200604281B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2008002427A1 (es) * 2007-08-16 2009-09-11 Boehringer Ingelheim Int Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2.
DE102008010661A1 (de) * 2008-02-22 2009-09-03 Dr. Felix Jäger und Dr. Stefan Drinkuth Laborgemeinschaft OHG Verfahren zur Herstellung von Pyridin-2-Boronsäure und Derivaten davon
CN102311448B (zh) * 2010-07-07 2014-02-19 中国科学院广州生物医药与健康研究院 噻吩并嘧啶酮类dpp-iv抑制剂
KR101985384B1 (ko) * 2011-07-15 2019-06-03 베링거 인겔하임 인터내셔날 게엠베하 치환된 퀴나졸린, 이의 제조 및 약제학적 조성물에서의 이의 용도
CN103450201B (zh) * 2012-05-30 2017-04-12 博瑞生物医药（苏州）股份有限公司 手性8‑（3‑氨基哌啶‑1‑基）‑黄嘌呤的制备方法
CN103709163B (zh) * 2012-09-29 2016-12-21 齐鲁制药有限公司 黄嘌呤衍生物、其制备方法及用途
CN103319483B (zh) * 2012-10-19 2016-08-03 药源药物化学（上海）有限公司 一种利拉列汀重要中间体的制备方法
CN106008507B (zh) * 2013-01-23 2017-11-28 成都苑东生物制药股份有限公司 黄嘌呤衍生物
TWI682931B (zh) * 2015-05-29 2020-01-21 大陸商江蘇天士力帝益藥業有限公司 黃嘌呤衍生物、其藥物組成物、其製劑以及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100408579C (zh) * 2001-02-24 2008-08-06 贝林格尔英格海姆法玛两合公司 黄嘌呤衍生物,其制法及其作为药物组合物的用途

Also Published As

Publication number Publication date
ZA200604281B (en) 2007-10-31
CN1980930A (zh) 2007-06-13
CN1980930B (zh) 2012-11-21
UA87835C2 (en) 2009-08-25
DE102004008112A1 (de) 2005-09-01

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