AR098215A1 - Compuesto heterocíclico - Google Patents
Compuesto heterocíclicoInfo
- Publication number
- AR098215A1 AR098215A1 ARP140104043A ARP140104043A AR098215A1 AR 098215 A1 AR098215 A1 AR 098215A1 AR P140104043 A ARP140104043 A AR P140104043A AR P140104043 A ARP140104043 A AR P140104043A AR 098215 A1 AR098215 A1 AR 098215A1
- Authority
- AR
- Argentina
- Prior art keywords
- optionally substituted
- independently represent
- ring
- group
- alkyl group
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- 101000829153 Homo sapiens Somatostatin receptor type 5 Proteins 0.000 abstract 1
- 102100023806 Somatostatin receptor type 5 Human genes 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 125000005049 dihydrooxadiazolyl group Chemical group O1N(NC=C1)* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013224093 | 2013-10-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR098215A1 true AR098215A1 (es) | 2016-05-18 |
Family
ID=51932560
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140104043A AR098215A1 (es) | 2013-10-29 | 2014-10-28 | Compuesto heterocíclico |
| ARP220103645A AR128158A2 (es) | 2013-10-29 | 2022-12-29 | Compuesto heterocíclico |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP220103645A AR128158A2 (es) | 2013-10-29 | 2022-12-29 | Compuesto heterocíclico |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US9120777B2 (enExample) |
| EP (1) | EP3063139B1 (enExample) |
| JP (1) | JP6450755B2 (enExample) |
| AR (2) | AR098215A1 (enExample) |
| CY (1) | CY1121279T1 (enExample) |
| DK (1) | DK3063139T3 (enExample) |
| ES (1) | ES2710657T3 (enExample) |
| HR (1) | HRP20190133T1 (enExample) |
| HU (1) | HUE041792T2 (enExample) |
| LT (1) | LT3063139T (enExample) |
| PL (1) | PL3063139T3 (enExample) |
| PT (1) | PT3063139T (enExample) |
| RS (1) | RS58321B1 (enExample) |
| SI (1) | SI3063139T1 (enExample) |
| SM (1) | SMT201900101T1 (enExample) |
| TR (1) | TR201901986T4 (enExample) |
| TW (1) | TWI668214B (enExample) |
| UY (1) | UY35801A (enExample) |
| WO (1) | WO2015064083A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2816032A4 (en) * | 2012-02-13 | 2015-09-30 | Takeda Pharmaceutical | AROMATIC RING CONNECTION |
| US9605000B2 (en) * | 2013-03-14 | 2017-03-28 | Takeda Pharmaceutical Company Limited | Spiro azetidine isoxazole derivatives and their use as SSTR antagonists |
| JO3442B1 (ar) | 2013-10-07 | 2019-10-20 | Takeda Pharmaceuticals Co | مضادات ذات نوع فرعي من مستقبل سوماتوستاتين 5 (sstr5) |
| EP4077310B1 (en) * | 2019-12-19 | 2024-05-01 | Université de Strasbourg | Sigma-1 receptor ligands and uses thereof |
| CN116354961B (zh) * | 2021-12-27 | 2025-07-25 | 中国科学院上海药物研究所 | 生长抑素受体5拮抗剂及其药物组合物及用途 |
| CN120752056A (zh) | 2023-03-27 | 2025-10-03 | 思可海雅药品株式会社 | 生长激素分泌促进剂 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5356906A (en) | 1989-10-27 | 1994-10-18 | The Du Pont Merck Pharmaceutical Company | (N-phthalimidoalkyl) piperidines useful as treatments for psychosis |
| ES2320973T3 (es) | 2000-06-12 | 2009-06-01 | EISAI R&D MANAGEMENT CO., LTD. | Compuestos de 1,2-dihidropiridina, procedimiento para su preparacion y uso de los mismos. |
| GB0129260D0 (en) | 2001-12-06 | 2002-01-23 | Eisai London Res Lab Ltd | Pharmaceutical compositions and their uses |
| CA2517888C (en) | 2003-03-14 | 2012-05-01 | Ono Pharmaceutical Co., Ltd. | Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient |
| KR20060123292A (ko) | 2003-11-10 | 2006-12-01 | 쉐링 악티엔게젤샤프트 | Ｃｃｒ-5 길항제로서 유용한 벤질에테르 아민 화합물 |
| JP2010500391A (ja) * | 2006-08-15 | 2010-01-07 | エフ．ホフマン−ラ ロシュ アーゲー | フェニル、ピリジン及びキノリン誘導体 |
| US7862825B2 (en) | 2007-02-21 | 2011-01-04 | Mladen Vranic | Method of controlling tight blood glucose by somatostatin receptor antagonists |
| US7799806B2 (en) * | 2007-04-04 | 2010-09-21 | Hoffmann-La Roche Inc. | Substituted n-benzyl piperidines as somatostatin receptor modulators |
| US20080306116A1 (en) | 2007-06-08 | 2008-12-11 | Christ Andreas D | Aryloxazole, aryloxadiazole and benzimidazole derivatives |
| TW200918062A (en) | 2007-09-12 | 2009-05-01 | Wyeth Corp | Azacyclylisoquinolinone and-isoindolinone derivatives as histamine-3 antagonists |
| AU2010245889A1 (en) | 2009-05-07 | 2011-11-03 | Merck Sharp & Dohme Corp. | Substituted spirocyclic amines useful as antidiabetic compounds |
| WO2012024183A1 (en) | 2010-08-18 | 2012-02-23 | Merck Sharp & Dohme Corp. | Spiroxazolidinone compounds |
| WO2012069917A1 (en) | 2010-11-26 | 2012-05-31 | Lupin Limited | Bicyclic gpr119 modulators |
| US9605000B2 (en) | 2013-03-14 | 2017-03-28 | Takeda Pharmaceutical Company Limited | Spiro azetidine isoxazole derivatives and their use as SSTR antagonists |
-
2014
- 2014-10-28 TW TW103137143A patent/TWI668214B/zh active
- 2014-10-28 TR TR2019/01986T patent/TR201901986T4/tr unknown
- 2014-10-28 RS RS20190190A patent/RS58321B1/sr unknown
- 2014-10-28 LT LTEP14800152.2T patent/LT3063139T/lt unknown
- 2014-10-28 EP EP14800152.2A patent/EP3063139B1/en active Active
- 2014-10-28 SI SI201431055T patent/SI3063139T1/sl unknown
- 2014-10-28 ES ES14800152T patent/ES2710657T3/es active Active
- 2014-10-28 HU HUE14800152A patent/HUE041792T2/hu unknown
- 2014-10-28 JP JP2016526960A patent/JP6450755B2/ja active Active
- 2014-10-28 WO PCT/JP2014/005438 patent/WO2015064083A1/en not_active Ceased
- 2014-10-28 AR ARP140104043A patent/AR098215A1/es active IP Right Grant
- 2014-10-28 US US14/525,593 patent/US9120777B2/en active Active
- 2014-10-28 PL PL14800152T patent/PL3063139T3/pl unknown
- 2014-10-28 UY UY0001035801A patent/UY35801A/es not_active Application Discontinuation
- 2014-10-28 PT PT14800152T patent/PT3063139T/pt unknown
- 2014-10-28 DK DK14800152.2T patent/DK3063139T3/en active
- 2014-10-28 HR HRP20190133TT patent/HRP20190133T1/hr unknown
- 2014-10-28 SM SM20190101T patent/SMT201900101T1/it unknown
-
2019
- 2019-02-14 CY CY20191100202T patent/CY1121279T1/el unknown
-
2022
- 2022-12-29 AR ARP220103645A patent/AR128158A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1121279T1 (el) | 2020-05-29 |
| WO2015064083A1 (en) | 2015-05-07 |
| SI3063139T1 (sl) | 2019-03-29 |
| PT3063139T (pt) | 2019-02-22 |
| JP2016535040A (ja) | 2016-11-10 |
| US9120777B2 (en) | 2015-09-01 |
| EP3063139A1 (en) | 2016-09-07 |
| UY35801A (es) | 2015-06-30 |
| TWI668214B (zh) | 2019-08-11 |
| PL3063139T3 (pl) | 2019-05-31 |
| LT3063139T (lt) | 2019-02-25 |
| TW201542539A (zh) | 2015-11-16 |
| TR201901986T4 (tr) | 2019-03-21 |
| AR128158A2 (es) | 2024-03-27 |
| RS58321B1 (sr) | 2019-03-29 |
| EP3063139B1 (en) | 2018-11-21 |
| DK3063139T3 (en) | 2019-03-11 |
| HRP20190133T1 (hr) | 2019-03-22 |
| HUE041792T2 (hu) | 2019-05-28 |
| JP6450755B2 (ja) | 2019-01-09 |
| SMT201900101T1 (it) | 2019-02-28 |
| ES2710657T3 (es) | 2019-04-26 |
| US20150119412A1 (en) | 2015-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR098215A1 (es) | Compuesto heterocíclico | |
| AR112348A1 (es) | Compuestos bicíclicos de pirazolo y triazolo como inhibidores de quinasas jak | |
| AR106053A1 (es) | Compuestos imidazo[4,5-c]quinolin-2-ona y su uso para el tratamiento del cáncer | |
| AR098908A1 (es) | Compuesto de (6s,9as)-n-bencil-6-[(4-hidroxifenil)metil]-4,7-dioxo-8-({6-[3-(piperazin-1-il)azetidin-1-il]piridin-2-il}metil)-2-(prop-2-en-1-il)-octahidro-1h-pirazino[2,1-c][1,2,4]triazina-1-carboxamida | |
| AR097932A1 (es) | Antagonista del receptor de somatostatina del subtipo 5 (sstr5) | |
| AR099177A1 (es) | Determinadas (2s)-n-[(1s)-1-ciano-2-feniletil]-1,4-oxazepan-2-carboxamidas como inhibidores de dipeptidil peptidasa 1 | |
| AR102204A1 (es) | Compuestos derivados de amino-alquilbenzotiazepinas | |
| CR20150509A (es) | Derivados de naftiridina utiles como antagonistas de la alfa-v-beta-6 integrina | |
| AR099400A1 (es) | Compuesto heterocíclico fusionado | |
| AR094668A1 (es) | Amidas como moduladores de canales de sodio | |
| AR092270A1 (es) | Sulfamoilarilamidas y su uso como medicamentos para el tratamiento de la hepatitis b | |
| AR097866A1 (es) | Derivados de 4-azaindol | |
| AR095311A1 (es) | 3-pirimidin-4-il-oxazolidin-2-onas como inhibidores de idh mutante | |
| AR101815A1 (es) | Compuestos y composiciones como inhibidores de quinasa | |
| AR098337A1 (es) | Triazolopirazina | |
| AR088828A1 (es) | DERIVADOS DE CICLOHEXILAMINA QUE TIENEN ACTIVIDAD COMO AGONISTAS ADRENERGICOS b2 Y COMO ANTAGONISTAS MUSCARINICOS M3 | |
| AR091781A1 (es) | Antagonistas del receptor de 5-ht3 | |
| AR093143A1 (es) | Compuestos de 2-aminopiridina | |
| AR105549A1 (es) | Compuestos de 1-alquil-6-oxo-1,6-dihidropiridin-3-ilo y usos de los mismos | |
| AR080703A1 (es) | Derivados de 3-(heteroaril-amino)-1,2,3,4-tetrahidro-9h-carbazol, moduladores de receptores de prostaglandina d2, composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento de trastornos alergicos o inmunitarios tales como asma. | |
| AR101479A1 (es) | Derivados de 6-alquinil-piridina | |
| AR088596A1 (es) | Compuestos de bencilamina sustituidos | |
| AR095570A1 (es) | Derivados de urea | |
| ES2571577T3 (es) | Derivados novedosos de morfolinilo útiles como inhibidores de MOGAT-2 | |
| AR100439A1 (es) | Derivados de carboxamida |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |