HRP20190133T1 - Heterociklički spoj - Google Patents

Heterociklički spoj

Info

Publication number
HRP20190133T1
HRP20190133T1 HRP20190133TT HRP20190133T HRP20190133T1 HR P20190133 T1 HRP20190133 T1 HR P20190133T1 HR P20190133T T HRP20190133T T HR P20190133TT HR P20190133 T HRP20190133 T HR P20190133T HR P20190133 T1 HRP20190133 T1 HR P20190133T1
Authority
HR
Croatia
Prior art keywords
heterocyclic compound
heterocyclic
compound
Prior art date
Application number
HRP20190133TT
Other languages
English (en)
Croatian (hr)
Inventor
Shizuo Kasai
Takashi Nakahata
Asato Kina
Hideki Hirose
Takeshi Yamasaki
Tohru Yamashita
Yoichi Nishikawa
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of HRP20190133T1 publication Critical patent/HRP20190133T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
HRP20190133TT 2013-10-29 2014-10-28 Heterociklički spoj HRP20190133T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013224093 2013-10-29
PCT/JP2014/005438 WO2015064083A1 (en) 2013-10-29 2014-10-28 Heterocyclic compound
EP14800152.2A EP3063139B1 (en) 2013-10-29 2014-10-28 Heterocyclic compound

Publications (1)

Publication Number Publication Date
HRP20190133T1 true HRP20190133T1 (hr) 2019-03-22

Family

ID=51932560

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20190133TT HRP20190133T1 (hr) 2013-10-29 2014-10-28 Heterociklički spoj

Country Status (19)

Country Link
US (1) US9120777B2 (enExample)
EP (1) EP3063139B1 (enExample)
JP (1) JP6450755B2 (enExample)
AR (2) AR098215A1 (enExample)
CY (1) CY1121279T1 (enExample)
DK (1) DK3063139T3 (enExample)
ES (1) ES2710657T3 (enExample)
HR (1) HRP20190133T1 (enExample)
HU (1) HUE041792T2 (enExample)
LT (1) LT3063139T (enExample)
PL (1) PL3063139T3 (enExample)
PT (1) PT3063139T (enExample)
RS (1) RS58321B1 (enExample)
SI (1) SI3063139T1 (enExample)
SM (1) SMT201900101T1 (enExample)
TR (1) TR201901986T4 (enExample)
TW (1) TWI668214B (enExample)
UY (1) UY35801A (enExample)
WO (1) WO2015064083A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2816032A4 (en) * 2012-02-13 2015-09-30 Takeda Pharmaceutical AROMATIC RING CONNECTION
US9605000B2 (en) * 2013-03-14 2017-03-28 Takeda Pharmaceutical Company Limited Spiro azetidine isoxazole derivatives and their use as SSTR antagonists
JO3442B1 (ar) 2013-10-07 2019-10-20 Takeda Pharmaceuticals Co مضادات ذات نوع فرعي من مستقبل سوماتوستاتين 5 (sstr5)
EP4077310B1 (en) * 2019-12-19 2024-05-01 Université de Strasbourg Sigma-1 receptor ligands and uses thereof
CN116354961B (zh) * 2021-12-27 2025-07-25 中国科学院上海药物研究所 生长抑素受体5拮抗剂及其药物组合物及用途
CN120752056A (zh) 2023-03-27 2025-10-03 思可海雅药品株式会社 生长激素分泌促进剂

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356906A (en) 1989-10-27 1994-10-18 The Du Pont Merck Pharmaceutical Company (N-phthalimidoalkyl) piperidines useful as treatments for psychosis
ES2320973T3 (es) 2000-06-12 2009-06-01 EISAI R&D MANAGEMENT CO., LTD. Compuestos de 1,2-dihidropiridina, procedimiento para su preparacion y uso de los mismos.
GB0129260D0 (en) 2001-12-06 2002-01-23 Eisai London Res Lab Ltd Pharmaceutical compositions and their uses
CA2517888C (en) 2003-03-14 2012-05-01 Ono Pharmaceutical Co., Ltd. Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient
KR20060123292A (ko) 2003-11-10 2006-12-01 쉐링 악티엔게젤샤프트 Ccr-5 길항제로서 유용한 벤질에테르 아민 화합물
JP2010500391A (ja) * 2006-08-15 2010-01-07 エフ.ホフマン−ラ ロシュ アーゲー フェニル、ピリジン及びキノリン誘導体
US7862825B2 (en) 2007-02-21 2011-01-04 Mladen Vranic Method of controlling tight blood glucose by somatostatin receptor antagonists
US7799806B2 (en) * 2007-04-04 2010-09-21 Hoffmann-La Roche Inc. Substituted n-benzyl piperidines as somatostatin receptor modulators
US20080306116A1 (en) 2007-06-08 2008-12-11 Christ Andreas D Aryloxazole, aryloxadiazole and benzimidazole derivatives
TW200918062A (en) 2007-09-12 2009-05-01 Wyeth Corp Azacyclylisoquinolinone and-isoindolinone derivatives as histamine-3 antagonists
AU2010245889A1 (en) 2009-05-07 2011-11-03 Merck Sharp & Dohme Corp. Substituted spirocyclic amines useful as antidiabetic compounds
WO2012024183A1 (en) 2010-08-18 2012-02-23 Merck Sharp & Dohme Corp. Spiroxazolidinone compounds
WO2012069917A1 (en) 2010-11-26 2012-05-31 Lupin Limited Bicyclic gpr119 modulators
US9605000B2 (en) 2013-03-14 2017-03-28 Takeda Pharmaceutical Company Limited Spiro azetidine isoxazole derivatives and their use as SSTR antagonists

Also Published As

Publication number Publication date
CY1121279T1 (el) 2020-05-29
WO2015064083A1 (en) 2015-05-07
SI3063139T1 (sl) 2019-03-29
PT3063139T (pt) 2019-02-22
JP2016535040A (ja) 2016-11-10
US9120777B2 (en) 2015-09-01
EP3063139A1 (en) 2016-09-07
UY35801A (es) 2015-06-30
TWI668214B (zh) 2019-08-11
AR098215A1 (es) 2016-05-18
PL3063139T3 (pl) 2019-05-31
LT3063139T (lt) 2019-02-25
TW201542539A (zh) 2015-11-16
TR201901986T4 (tr) 2019-03-21
AR128158A2 (es) 2024-03-27
RS58321B1 (sr) 2019-03-29
EP3063139B1 (en) 2018-11-21
DK3063139T3 (en) 2019-03-11
HUE041792T2 (hu) 2019-05-28
JP6450755B2 (ja) 2019-01-09
SMT201900101T1 (it) 2019-02-28
ES2710657T3 (es) 2019-04-26
US20150119412A1 (en) 2015-04-30

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