AR093449A1 - Polvo farmaceutico compuesto de nucleo-recubrimiento y procedimientos para producirlo - Google Patents

Polvo farmaceutico compuesto de nucleo-recubrimiento y procedimientos para producirlo

Info

Publication number
AR093449A1
AR093449A1 ARP130104150A ARP130104150A AR093449A1 AR 093449 A1 AR093449 A1 AR 093449A1 AR P130104150 A ARP130104150 A AR P130104150A AR P130104150 A ARP130104150 A AR P130104150A AR 093449 A1 AR093449 A1 AR 093449A1
Authority
AR
Argentina
Prior art keywords
particles
composite particle
core
sodium
composite
Prior art date
Application number
ARP130104150A
Other languages
English (en)
Spanish (es)
Inventor
To Daniel
A Azad Mohammed
dave Rajesh
A Bilgili Ecevit
Knieke Catharina
Original Assignee
New Jersey Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New Jersey Inst Technology filed Critical New Jersey Inst Technology
Publication of AR093449A1 publication Critical patent/AR093449A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/501Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D1/00Processes for applying liquids or other fluent materials
    • B05D1/18Processes for applying liquids or other fluent materials performed by dipping
    • B05D1/22Processes for applying liquids or other fluent materials performed by dipping using fluidised-bed technique

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
ARP130104150A 2012-11-12 2013-11-12 Polvo farmaceutico compuesto de nucleo-recubrimiento y procedimientos para producirlo AR093449A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261725301P 2012-11-12 2012-11-12

Publications (1)

Publication Number Publication Date
AR093449A1 true AR093449A1 (es) 2015-06-10

Family

ID=50685172

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130104150A AR093449A1 (es) 2012-11-12 2013-11-12 Polvo farmaceutico compuesto de nucleo-recubrimiento y procedimientos para producirlo

Country Status (9)

Country Link
US (1) US9801820B2 (https=)
EP (1) EP2916824B1 (https=)
JP (1) JP6460562B2 (https=)
CN (1) CN104968332B (https=)
AR (1) AR093449A1 (https=)
BR (1) BR112015010704B8 (https=)
DK (1) DK2916824T3 (https=)
ES (1) ES2745759T3 (https=)
WO (1) WO2014074808A1 (https=)

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US10149826B2 (en) * 2015-01-20 2018-12-11 Hyalo Technologies, LLC Method of preparing microspheres
WO2017047650A1 (ja) * 2015-09-14 2017-03-23 大和製罐株式会社 粉末吸入剤、吸入器、及び粉末吸入剤の製造方法
CN108024912A (zh) * 2015-09-24 2018-05-11 荷兰联合利华有限公司 口腔护理组合物
US9675609B2 (en) 2015-11-11 2017-06-13 Cao Pharmaceuticals Inc. Nano- and micro-sized particles of 20-camptothecin or derivative thereof and pharmaceutical compositions containing same, and treatment of cancers therewith
JP6067154B1 (ja) * 2016-01-25 2017-01-25 株式会社樋口商会 コーティング粒子の製造方法
KR101809139B1 (ko) 2016-11-15 2017-12-15 주식회사 이코블록 무기물 코어에 유기물을 코팅하는 방법 및 그에 따른 용사코팅장치
JP6935501B2 (ja) * 2017-08-25 2021-09-15 福田金属箔粉工業株式会社 積層造形用粉末の評価方法
DE102017215328A1 (de) * 2017-09-01 2019-03-07 Henkel Ag & Co. Kgaa Treibmittelhaltige kosmetische Zusammensetzungen mit Pigment-haltigen Stärkepartikeln und anionischem Polymer
CN107649063B (zh) * 2017-11-02 2023-08-29 黑龙江省科学院自动化研究所 一种纳米材料超声共振乳化混配装置
US12097204B2 (en) 2018-09-03 2024-09-24 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Solid pharmaceutical composition containing 1,3,5-triazine derivative or salt thereof
CN109046187B (zh) * 2018-10-09 2023-05-23 天津西敦津洋环保科技有限公司 一种高充气率的气固流化床反应器、实现在流化床中高充气率的方法及其应用
JP7147523B2 (ja) * 2018-12-06 2022-10-05 三生医薬株式会社 造粒方法
US11549381B2 (en) * 2019-09-05 2023-01-10 Raytheon Technologies Corporation Coating fabrication method for producing engineered microstructure of silicate-resistant barrier coating
JP2023505142A (ja) * 2019-12-02 2023-02-08 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 活性医薬成分のナノ懸濁液の担体上の堆積
CN114786739B (zh) * 2019-12-16 2023-10-31 固特异轮胎和橡胶公司 二氧化硅涂覆的淀粉
KR20220144378A (ko) * 2020-02-19 2022-10-26 나노 파마솔루션즈, 인코포레이티드 치료제 나노입자 및 제조 방법
CN112522863B (zh) * 2020-11-26 2021-12-07 内蒙古工业大学 气流铺覆纤维装置
EP4507510A4 (en) * 2022-04-10 2026-03-25 Incredo Ltd COATED SWEETENER PARTICLES
CN115386208B (zh) * 2022-08-11 2025-06-24 长兴电子(苏州)有限公司 可降解微珠及其制备方法与应用
TWI859571B (zh) * 2022-08-29 2024-10-21 長興材料工業股份有限公司 可降解微珠及其製備方法與應用
TWI842445B (zh) * 2023-03-21 2024-05-11 國立臺灣海洋大學 含有褐藻萃取物的多層顆粒結構及其製造方法
CN119555851B (zh) * 2025-02-06 2025-06-03 上海新黄河制药有限公司 一种吸入用混悬液的体外溶出曲线测定方法

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GB9515182D0 (en) 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
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JP4547888B2 (ja) * 2003-10-10 2010-09-22 小野薬品工業株式会社 胃内浮遊性固形製剤
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KR20090005237A (ko) 2006-05-22 2009-01-12 테바 파마슈티컬 인더스트리즈 리미티드 둘록세틴 염산염 지연 방출형 제제
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US8993041B2 (en) * 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them

Also Published As

Publication number Publication date
EP2916824A1 (en) 2015-09-16
ES2745759T3 (es) 2020-03-03
EP2916824B1 (en) 2019-06-19
BR112015010704B1 (pt) 2022-05-31
WO2014074808A1 (en) 2014-05-15
CN104968332B (zh) 2020-10-20
CN104968332A (zh) 2015-10-07
EP2916824A4 (en) 2016-08-17
US9801820B2 (en) 2017-10-31
BR112015010704B8 (pt) 2022-06-14
DK2916824T3 (da) 2019-09-30
JP6460562B2 (ja) 2019-01-30
US20150297521A1 (en) 2015-10-22
JP2016503411A (ja) 2016-02-04
BR112015010704A2 (pt) 2017-07-11

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