AR091948A1 - Produccion de ganado resistente al fmdv (virus de la fiebre aftosa) por medio de la sustitucion de alelos - Google Patents
Produccion de ganado resistente al fmdv (virus de la fiebre aftosa) por medio de la sustitucion de alelosInfo
- Publication number
- AR091948A1 AR091948A1 ARP130102723A ARP130102723A AR091948A1 AR 091948 A1 AR091948 A1 AR 091948A1 AR P130102723 A ARP130102723 A AR P130102723A AR P130102723 A ARP130102723 A AR P130102723A AR 091948 A1 AR091948 A1 AR 091948A1
- Authority
- AR
- Argentina
- Prior art keywords
- eif4g
- resistant
- embryo
- livestock
- modified
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 3
- 244000144972 livestock Species 0.000 title 2
- 206010037660 Pyrexia Diseases 0.000 title 1
- 101710091919 Eukaryotic translation initiation factor 4G Proteins 0.000 abstract 9
- 210000001161 mammalian embryo Anatomy 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 208000007212 Foot-and-Mouth Disease Diseases 0.000 abstract 3
- 241000710198 Foot-and-mouth disease virus Species 0.000 abstract 3
- 108091005804 Peptidases Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 102000001708 Protein Isoforms Human genes 0.000 abstract 2
- 108010029485 Protein Isoforms Proteins 0.000 abstract 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 2
- 230000004075 alteration Effects 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 230000002797 proteolythic effect Effects 0.000 abstract 2
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 235000003869 genetically modified organism Nutrition 0.000 abstract 1
- 235000019833 protease Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/101—Bovine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261677904P | 2012-07-31 | 2012-07-31 | |
| US13/836,860 US10058078B2 (en) | 2012-07-31 | 2013-03-15 | Production of FMDV-resistant livestock by allele substitution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR091948A1 true AR091948A1 (es) | 2015-03-11 |
Family
ID=50026918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130102723A AR091948A1 (es) | 2012-07-31 | 2013-07-31 | Produccion de ganado resistente al fmdv (virus de la fiebre aftosa) por medio de la sustitucion de alelos |
Country Status (15)
Families Citing this family (50)
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| BR112012020257A8 (pt) * | 2010-02-11 | 2018-02-14 | Recombinetics Inc | métodos e aparelhos para produzir artiodátilos transgênicos |
| US10920242B2 (en) | 2011-02-25 | 2021-02-16 | Recombinetics, Inc. | Non-meiotic allele introgression |
| US9528124B2 (en) | 2013-08-27 | 2016-12-27 | Recombinetics, Inc. | Efficient non-meiotic allele introgression |
| CA2853829C (en) | 2011-07-22 | 2023-09-26 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| US10058078B2 (en) | 2012-07-31 | 2018-08-28 | Recombinetics, Inc. | Production of FMDV-resistant livestock by allele substitution |
| WO2014186585A2 (en) * | 2013-05-15 | 2014-11-20 | Sangamo Biosciences, Inc. | Methods and compositions for treatment of a genetic condition |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| AU2014337790B2 (en) | 2013-10-25 | 2019-09-26 | Livestock Improvement Corporation Limited | Genetic markers and uses therefor |
| CN111218447B (zh) | 2013-11-07 | 2024-10-11 | 爱迪塔斯医药有限公司 | 使用统治型gRNA的CRISPR相关方法和组合物 |
| US20150166982A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting pi3k point mutations |
| US20180142307A1 (en) * | 2014-02-11 | 2018-05-24 | California Institute Of Technology | Recording and mapping lineage information and molecular events in individual cells |
| US10349639B2 (en) * | 2014-03-26 | 2019-07-16 | University Of Maryland, College Park | Targeted genome editing in zygotes of domestic large animals |
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| GB201617559D0 (en) | 2016-10-17 | 2016-11-30 | University Court Of The University Of Edinburgh The | Swine comprising modified cd163 and associated methods |
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| KR20240116572A (ko) | 2017-03-23 | 2024-07-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
| US11560566B2 (en) | 2017-05-12 | 2023-01-24 | President And Fellows Of Harvard College | Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation |
| EP3658573A1 (en) | 2017-07-28 | 2020-06-03 | President and Fellows of Harvard College | Methods and compositions for evolving base editors using phage-assisted continuous evolution (pace) |
| WO2019139645A2 (en) | 2017-08-30 | 2019-07-18 | President And Fellows Of Harvard College | High efficiency base editors comprising gam |
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| CN104080462B (zh) | 2011-12-16 | 2019-08-09 | 塔尔盖特基因生物技术有限公司 | 用于修饰预定的靶核酸序列的组合物和方法 |
| US20130212722A1 (en) | 2012-02-15 | 2013-08-15 | Mice With Horns, Llc | Transgenic animals with customizable traits |
| US10174331B2 (en) | 2012-05-07 | 2019-01-08 | Sangamo Therapeutics, Inc. | Methods and compositions for nuclease-mediated targeted integration of transgenes |
| US20150291951A1 (en) | 2012-06-22 | 2015-10-15 | Mayo Foundation For Medical Education And Research | Genome editing |
| US10058078B2 (en) | 2012-07-31 | 2018-08-28 | Recombinetics, Inc. | Production of FMDV-resistant livestock by allele substitution |
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2013
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- 2013-07-19 MX MX2015001299A patent/MX366723B/es active IP Right Grant
- 2013-07-19 WO PCT/US2013/051222 patent/WO2014022120A1/en not_active Ceased
- 2013-07-19 NZ NZ629582A patent/NZ629582A/en not_active IP Right Cessation
- 2013-07-19 EP EP13825988.2A patent/EP2880153A4/en not_active Ceased
- 2013-07-19 CA CA2880616A patent/CA2880616A1/en not_active Abandoned
- 2013-07-19 AU AU2013296901A patent/AU2013296901B2/en not_active Ceased
- 2013-07-19 BR BR112015002280A patent/BR112015002280A2/pt not_active Application Discontinuation
- 2013-07-19 RU RU2015106818A patent/RU2015106818A/ru not_active Application Discontinuation
- 2013-07-19 KR KR1020157005357A patent/KR20150036792A/ko not_active Ceased
- 2013-07-19 JP JP2015525450A patent/JP6446360B2/ja not_active Expired - Fee Related
- 2013-07-19 EP EP19159141.1A patent/EP3540050A1/en not_active Withdrawn
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2015
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2018
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| CL2015000248A1 (es) | 2015-10-02 |
| BR112015002280A2 (pt) | 2019-01-15 |
| PH12015500213A1 (en) | 2015-03-30 |
| MX2015001299A (es) | 2015-06-05 |
| WO2014022120A1 (en) | 2014-02-06 |
| EP2880153A1 (en) | 2015-06-10 |
| AU2013296901B2 (en) | 2019-05-09 |
| JP2015523098A (ja) | 2015-08-13 |
| KR20150036792A (ko) | 2015-04-07 |
| US20140041066A1 (en) | 2014-02-06 |
| US20180310536A1 (en) | 2018-11-01 |
| JP6446360B2 (ja) | 2018-12-26 |
| CA2880616A1 (en) | 2014-02-06 |
| US10058078B2 (en) | 2018-08-28 |
| EP2880153A4 (en) | 2016-03-30 |
| EP3540050A1 (en) | 2019-09-18 |
| CN104837989A (zh) | 2015-08-12 |
| NZ629582A (en) | 2017-07-28 |
| RU2015106818A (ru) | 2016-09-27 |
| AU2013296901A1 (en) | 2015-02-12 |
| MX366723B (es) | 2019-07-22 |
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