AR090775A1 - Preparado inyectable - Google Patents
Preparado inyectableInfo
- Publication number
- AR090775A1 AR090775A1 ARP130101320A ARP130101320A AR090775A1 AR 090775 A1 AR090775 A1 AR 090775A1 AR P130101320 A ARP130101320 A AR P130101320A AR P130101320 A ARP130101320 A AR P130101320A AR 090775 A1 AR090775 A1 AR 090775A1
- Authority
- AR
- Argentina
- Prior art keywords
- water
- injectable preparation
- tocopherol
- quinolin
- piperazin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261636932P | 2012-04-23 | 2012-04-23 | |
| US201361791896P | 2013-03-15 | 2013-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR090775A1 true AR090775A1 (es) | 2014-12-03 |
Family
ID=49483139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130101320A AR090775A1 (es) | 2012-04-23 | 2013-04-22 | Preparado inyectable |
Country Status (31)
| Country | Link |
|---|---|
| US (6) | US20150086632A1 (enExample) |
| EP (1) | EP2868318B2 (enExample) |
| JP (1) | JP6249944B2 (enExample) |
| KR (1) | KR102168263B1 (enExample) |
| CN (4) | CN110638752A (enExample) |
| AR (1) | AR090775A1 (enExample) |
| AU (1) | AU2013253518B2 (enExample) |
| BR (1) | BR112014026398B1 (enExample) |
| CA (1) | CA2871398C (enExample) |
| CO (1) | CO7151499A2 (enExample) |
| CY (1) | CY1123195T1 (enExample) |
| DK (1) | DK2868318T4 (enExample) |
| EA (1) | EA026124B1 (enExample) |
| ES (1) | ES2727454T5 (enExample) |
| HR (1) | HRP20190841T4 (enExample) |
| HU (1) | HUE043686T2 (enExample) |
| IL (1) | IL235211A0 (enExample) |
| IN (1) | IN2014DN08870A (enExample) |
| JO (1) | JO3524B1 (enExample) |
| LT (1) | LT2868318T (enExample) |
| MX (1) | MX361722B (enExample) |
| MY (1) | MY169099A (enExample) |
| NZ (1) | NZ630255A (enExample) |
| PH (1) | PH12014502366A1 (enExample) |
| PL (1) | PL2868318T5 (enExample) |
| PT (1) | PT2868318T (enExample) |
| SG (2) | SG11201406775UA (enExample) |
| SI (1) | SI2868318T2 (enExample) |
| TW (1) | TWI641395B (enExample) |
| UA (1) | UA118084C2 (enExample) |
| WO (1) | WO2013161830A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20200109A1 (ar) | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
| TWI562991B (en) * | 2012-04-23 | 2016-12-21 | Otsuka Pharma Co Ltd | Dihydrate of benzothiophene compound or of a salt thereof, and process for producing the same |
| HK1212609A1 (zh) * | 2012-10-25 | 2016-06-17 | 大塚制药株式会社 | 含有依匹唑派或其盐的用於与神经变性疾病相关的行为和精神症状或与精神疾病相关的冲动症状的预防和/或治疗剂 |
| WO2017106641A1 (en) * | 2015-12-17 | 2017-06-22 | Assia Chemical Industries Ltd. | Solid state forms of brexpiprazole |
| US10501450B2 (en) | 2016-02-01 | 2019-12-10 | Hexal Ag | Anhydrate-free polymorphically pure micronized crystalline brexpiprazole di-hydrate for use in intramuscular injectable sustained release formulations |
| WO2017208251A1 (en) * | 2016-05-31 | 2017-12-07 | Cipla Limited | A new stable polymorph of brexpiprazole and process for preparation thereof |
| EP3500249A1 (en) | 2016-08-16 | 2019-06-26 | Hexal Aktiengesellschaft | Pharmaceutical compositions of a benzothiophene compound |
| US11072605B2 (en) * | 2017-02-02 | 2021-07-27 | Hexal Ag | Crystalline brexpiprazole |
| KR20210144810A (ko) * | 2019-03-28 | 2021-11-30 | 오츠카 세이야쿠 가부시키가이샤 | 벤조아제핀 화합물-함유 동결건조 조성물 |
| WO2021029020A1 (ja) * | 2019-08-13 | 2021-02-18 | 大塚製薬株式会社 | 経口医薬組成物 |
| CA3225183A1 (en) | 2021-09-07 | 2023-03-16 | Ming Li | Long-acting brexpiprazole preparation for injection and preparation method therefor |
| CN117214053A (zh) * | 2023-10-17 | 2023-12-12 | 海南卫康制药(潜山)有限公司 | 一种注射用头孢呋辛钠肌注混悬液的粒度测定方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6274634B1 (en) | 1997-05-14 | 2001-08-14 | Senju Pharmaceutical Co., Ltd. | Aqueous suspension preparations with excellent redispersibility |
| JP3402195B2 (ja) * | 1997-05-14 | 2003-04-28 | 千寿製薬株式会社 | 再分散性の良い水性懸濁液剤 |
| US6656505B2 (en) * | 2000-07-21 | 2003-12-02 | Alpharma Uspd Inc. | Method for forming an aqueous flocculated suspension |
| ES2396598T3 (es) * | 2000-08-25 | 2013-02-22 | Senju Pharmaceutical Co., Ltd. | Preparaciones en forma de suspensiones acuosas |
| AR033485A1 (es) * | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma |
| US20050032811A1 (en) * | 2003-08-06 | 2005-02-10 | Josiah Brown | Methods for administering aripiprazole |
| BRPI0415531B8 (pt) * | 2003-10-23 | 2021-05-25 | Otsuka Pharma Co Ltd | formulação de aripiprazol injetável estéril de liberação controlada e método para a sua preparação |
| JP4315393B2 (ja) * | 2005-04-14 | 2009-08-19 | 大塚製薬株式会社 | 複素環化合物 |
| TWI320783B (en) * | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
| CA2622758A1 (en) | 2005-09-15 | 2007-03-29 | Elan Pharma International, Limited | Nanoparticulate aripiprazole formulations |
| TW200808375A (en) * | 2006-05-12 | 2008-02-16 | Otsuka Pharma Co Ltd | Hydrogel suspension and manufacturing process thereof |
| TWI415629B (zh) | 2006-10-26 | 2013-11-21 | Otsuka Pharma Co Ltd | 含有瑞巴匹特之水性醫藥懸浮物及其製造方法 |
| JP4879349B2 (ja) * | 2007-07-31 | 2012-02-22 | 大塚製薬株式会社 | アリピプラゾール懸濁液及び凍結乾燥製剤の製造方法 |
| PT2262506E (pt) * | 2008-03-11 | 2014-06-24 | Alcon Res Ltd | Suspensões de acetonido de triamcinolona de baixa viscosidade altamente floculadas para injeção intravítrea |
| US20100125060A1 (en) * | 2008-11-19 | 2010-05-20 | Majid Razzak | Formulations comprising ceftiofur and ketoprofen or ceftiofur and benzyl alcohol |
| PH12012502076A1 (en) * | 2010-08-24 | 2013-02-04 | Otsuka Pharma Co Ltd | Suspension and cake composition containing carbostyryl derivative and silicone oil and/or silicone oil derivative |
| CN107595771A (zh) * | 2010-10-18 | 2018-01-19 | 大日本住友制药株式会社 | 注射用缓释制剂 |
| US9034867B2 (en) * | 2011-03-18 | 2015-05-19 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising sorbitan esters |
| JP2012232958A (ja) | 2011-05-09 | 2012-11-29 | Otsuka Pharmaceut Co Ltd | 注射製剤 |
| WO2013142205A1 (en) * | 2012-03-19 | 2013-09-26 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising benzyl alcohol |
| TWI562991B (en) * | 2012-04-23 | 2016-12-21 | Otsuka Pharma Co Ltd | Dihydrate of benzothiophene compound or of a salt thereof, and process for producing the same |
| JOP20200109A1 (ar) * | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
-
2013
- 2013-04-22 AR ARP130101320A patent/AR090775A1/es not_active Application Discontinuation
- 2013-04-23 CN CN201911077087.1A patent/CN110638752A/zh active Pending
- 2013-04-23 AU AU2013253518A patent/AU2013253518B2/en active Active
- 2013-04-23 US US14/395,681 patent/US20150086632A1/en not_active Abandoned
- 2013-04-23 PT PT13781458T patent/PT2868318T/pt unknown
- 2013-04-23 HU HUE13781458A patent/HUE043686T2/hu unknown
- 2013-04-23 SG SG11201406775UA patent/SG11201406775UA/en unknown
- 2013-04-23 SI SI201331442T patent/SI2868318T2/sl unknown
- 2013-04-23 EA EA201491937A patent/EA026124B1/ru not_active IP Right Cessation
- 2013-04-23 PL PL13781458T patent/PL2868318T5/pl unknown
- 2013-04-23 WO PCT/JP2013/061950 patent/WO2013161830A1/ja not_active Ceased
- 2013-04-23 JO JOP/2013/0115A patent/JO3524B1/ar active
- 2013-04-23 LT LTEP13781458.8T patent/LT2868318T/lt unknown
- 2013-04-23 KR KR1020147032097A patent/KR102168263B1/ko active Active
- 2013-04-23 CA CA2871398A patent/CA2871398C/en active Active
- 2013-04-23 EP EP13781458.8A patent/EP2868318B2/en active Active
- 2013-04-23 HR HRP20190841TT patent/HRP20190841T4/hr unknown
- 2013-04-23 JP JP2014512621A patent/JP6249944B2/ja active Active
- 2013-04-23 SG SG10201608684QA patent/SG10201608684QA/en unknown
- 2013-04-23 UA UAA201412554A patent/UA118084C2/uk unknown
- 2013-04-23 MX MX2014012734A patent/MX361722B/es active IP Right Grant
- 2013-04-23 BR BR112014026398-1A patent/BR112014026398B1/pt active IP Right Grant
- 2013-04-23 NZ NZ630255A patent/NZ630255A/en unknown
- 2013-04-23 MY MYPI2014703102A patent/MY169099A/en unknown
- 2013-04-23 TW TW102114433A patent/TWI641395B/zh active
- 2013-04-23 CN CN201380021612.2A patent/CN104363912A/zh active Pending
- 2013-04-23 CN CN201710701596.1A patent/CN107536802A/zh active Pending
- 2013-04-23 IN IN8870DEN2014 patent/IN2014DN08870A/en unknown
- 2013-04-23 DK DK13781458.8T patent/DK2868318T4/da active
- 2013-04-23 CN CN202010921162.4A patent/CN111888329A/zh active Pending
- 2013-04-23 ES ES13781458T patent/ES2727454T5/es active Active
-
2014
- 2014-10-20 IL IL235211A patent/IL235211A0/en active IP Right Grant
- 2014-10-22 PH PH12014502366A patent/PH12014502366A1/en unknown
- 2014-11-21 CO CO14255947A patent/CO7151499A2/es unknown
-
2017
- 2017-09-12 US US15/702,361 patent/US10624889B2/en active Active
-
2019
- 2019-06-06 CY CY20191100602T patent/CY1123195T1/el unknown
-
2020
- 2020-01-28 US US16/775,222 patent/US20200163960A1/en not_active Abandoned
-
2022
- 2022-02-11 US US17/650,822 patent/US20220305007A1/en not_active Abandoned
-
2023
- 2023-12-15 US US18/541,083 patent/US20240277702A1/en not_active Abandoned
-
2024
- 2024-11-22 US US18/956,268 patent/US20250241909A1/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |