AR089117A1 - Elemento integrador y conjugador de actinomiceto de actinoplanes sp. se50/110 como plasmido para la transformacion genetica de actinobacterias relacionadas - Google Patents

Elemento integrador y conjugador de actinomiceto de actinoplanes sp. se50/110 como plasmido para la transformacion genetica de actinobacterias relacionadas

Info

Publication number
AR089117A1
AR089117A1 ARP120104603A ARP120104603A AR089117A1 AR 089117 A1 AR089117 A1 AR 089117A1 AR P120104603 A ARP120104603 A AR P120104603A AR P120104603 A ARP120104603 A AR P120104603A AR 089117 A1 AR089117 A1 AR 089117A1
Authority
AR
Argentina
Prior art keywords
actinoplanes
alce
conjugator
integrator
actinomicet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ARP120104603A
Other languages
English (en)
Inventor
Dr Wehlmann Hermann
Prof Dr Puehler Alfred
Dr Klein Andreas
Dr Selber Klaus
Dr Rosen Winfried
Schwientek Patrick
Dr Kalinowski Jrn
Dr Wehmeier Udo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Intellectual Property GmbH
Original Assignee
Bayer Intellectual Property GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Intellectual Property GmbH filed Critical Bayer Intellectual Property GmbH
Publication of AR089117A1 publication Critical patent/AR089117A1/es
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/365—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinoplanes (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente se refiere a una secuencia de ADN innata dentro de la secuencia del genoma completo de Actinoplanes sp. SE50/110 que se asemeja a la estructura de un elemento integrador y conjugador de actinomiceto (AlCE). Se utilizaron AlCE relacionados para establecer herramientas de manipulación genética para otras bacterias en el pasado. En este documento, se describen las características únicas del AlCE específico encontrado en Actinoplanes sp. SE50/110 que es claramente diferente de cualquier otro AlCE conocido en su totalidad, pero comparte partes menores con similitud de secuencia variable con otros AlCE caracterizados de otras especies.
ARP120104603A 2011-12-08 2012-12-07 Elemento integrador y conjugador de actinomiceto de actinoplanes sp. se50/110 como plasmido para la transformacion genetica de actinobacterias relacionadas Pending AR089117A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11192618 2011-12-08

Publications (1)

Publication Number Publication Date
AR089117A1 true AR089117A1 (es) 2014-07-30

Family

ID=47278320

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120104603A Pending AR089117A1 (es) 2011-12-08 2012-12-07 Elemento integrador y conjugador de actinomiceto de actinoplanes sp. se50/110 como plasmido para la transformacion genetica de actinobacterias relacionadas

Country Status (12)

Country Link
US (2) US9217154B2 (es)
EP (1) EP2788373B1 (es)
JP (1) JP2015501641A (es)
KR (1) KR20140109922A (es)
CN (1) CN104144942A (es)
AR (1) AR089117A1 (es)
CA (1) CA2858259A1 (es)
ES (1) ES2718331T3 (es)
HK (1) HK1203970A1 (es)
IL (1) IL232587A (es)
IN (1) IN2014CN04155A (es)
WO (1) WO2013083566A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2718331T3 (es) 2011-12-08 2019-07-01 Bayer Ip Gmbh Nuevo elemento integrador y conjugador de actinomiceto de Actinoplanes sp. SE50/110 como plásmido para la transformación genética de actinobacterias relacionadas
CN112592878B (zh) * 2020-12-25 2022-08-26 上海交通大学 增强正调控蛋白基因表达以提高阿卡波糖发酵水平的方法
CN112522174B (zh) * 2020-12-25 2022-08-09 上海交通大学 一种敲除负调控蛋白基因以提高阿卡波糖发酵水平的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2064092C2 (de) 1970-12-28 1983-06-01 Bayer Ag, 5090 Leverkusen Inhibitoren für Glykosidhydrolasen aus Actinomyceten
DE2209834C3 (de) 1972-03-01 1978-04-20 Bayer Ag, 5090 Leverkusen Herstellung von Saccharase-Inhibitoren
DE2347782C3 (de) 1973-09-22 1979-10-11 Bayer Ag, 5090 Leverkusen Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4062950A (en) 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
EP0796915A3 (de) * 1996-03-22 1999-04-14 Bayer Ag Verfahren zur Herstellung sowie zur Verwendung von Acarviosyl-Transferase bei der Umwandlung von Acarbose-Homologen in Acarbose, zur Herstellung von Acarbose-Homologen
EP2173880A2 (en) * 2007-07-27 2010-04-14 Wyeth a Corporation of the State of Delaware Vectors and methods for cloning gene clusters or portions thereof
TW201217533A (en) * 2010-08-04 2012-05-01 Bayer Pharma AG Genomics of actinoplanes utahensis
ES2718331T3 (es) 2011-12-08 2019-07-01 Bayer Ip Gmbh Nuevo elemento integrador y conjugador de actinomiceto de Actinoplanes sp. SE50/110 como plásmido para la transformación genética de actinobacterias relacionadas

Also Published As

Publication number Publication date
US9562249B2 (en) 2017-02-07
KR20140109922A (ko) 2014-09-16
JP2015501641A (ja) 2015-01-19
EP2788373A1 (en) 2014-10-15
US20140349346A1 (en) 2014-11-27
CA2858259A1 (en) 2013-06-13
IL232587A0 (en) 2014-06-30
HK1203970A1 (en) 2015-11-06
ES2718331T3 (es) 2019-07-01
IN2014CN04155A (es) 2015-07-17
IL232587A (en) 2017-08-31
CN104144942A (zh) 2014-11-12
US20160130622A1 (en) 2016-05-12
EP2788373B1 (en) 2019-01-23
WO2013083566A1 (en) 2013-06-13
US9217154B2 (en) 2015-12-22

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