AR083756A1 - Formas solidas del 3-(4-(aminometil)-1-(5-metil-7h-pirrolo[2,3-d]pirimidin-4-il)piperidin-4-carboxamido)fenil dimetilcarbamato - Google Patents
Formas solidas del 3-(4-(aminometil)-1-(5-metil-7h-pirrolo[2,3-d]pirimidin-4-il)piperidin-4-carboxamido)fenil dimetilcarbamatoInfo
- Publication number
- AR083756A1 AR083756A1 ARP110104111A ARP110104111A AR083756A1 AR 083756 A1 AR083756 A1 AR 083756A1 AR P110104111 A ARP110104111 A AR P110104111A AR P110104111 A ARP110104111 A AR P110104111A AR 083756 A1 AR083756 A1 AR 083756A1
- Authority
- AR
- Argentina
- Prior art keywords
- methyl
- piperidin
- crystalline compound
- carboxamido
- pyrrolo
- Prior art date
Links
- 239000007787 solid Substances 0.000 title abstract 2
- DPBWFNDFMCCGGJ-UHFFFAOYSA-N 4-Piperidine carboxamide Chemical compound NC(=O)C1CCNCC1 DPBWFNDFMCCGGJ-UHFFFAOYSA-N 0.000 title 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- -1 3- (4- (aminomethyl) -1- (5-methyl-7H-pyrrolo [2,3-d] pyrimidin-4-yl) piperidin-4-carboxamido) phenyl Chemical group 0.000 abstract 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000002844 melting Methods 0.000 abstract 2
- 230000008018 melting Effects 0.000 abstract 2
- MYOHNZJKOAODMX-UHFFFAOYSA-N phenyl n,n-dimethylcarbamate Chemical compound CN(C)C(=O)OC1=CC=CC=C1 MYOHNZJKOAODMX-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41060210P | 2010-11-05 | 2010-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR083756A1 true AR083756A1 (es) | 2013-03-20 |
Family
ID=45002136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP110104111A AR083756A1 (es) | 2010-11-05 | 2011-11-04 | Formas solidas del 3-(4-(aminometil)-1-(5-metil-7h-pirrolo[2,3-d]pirimidin-4-il)piperidin-4-carboxamido)fenil dimetilcarbamato |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8735408B2 (enExample) |
| EP (1) | EP2635584A1 (enExample) |
| JP (1) | JP2013541588A (enExample) |
| KR (1) | KR20140003433A (enExample) |
| CN (1) | CN103298815A (enExample) |
| AR (1) | AR083756A1 (enExample) |
| AU (1) | AU2011323371A1 (enExample) |
| BR (1) | BR112013011094A2 (enExample) |
| CA (1) | CA2817112A1 (enExample) |
| IL (1) | IL225884A0 (enExample) |
| MX (1) | MX2013004923A (enExample) |
| RU (1) | RU2013125755A (enExample) |
| SG (1) | SG190098A1 (enExample) |
| TW (1) | TW201302754A (enExample) |
| WO (1) | WO2012061565A1 (enExample) |
| ZA (1) | ZA201302996B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015150337A1 (en) | 2014-04-01 | 2015-10-08 | Amakem Nv | Lim kinase inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI439457B (zh) * | 2007-09-28 | 2014-06-01 | Lexicon Pharmaceuticals Inc | （ｓ）－２－胺基－３－（４－（２－胺基－６－（（ｒ）－１－（４－氯－２－（３－甲基－１ｈ－吡唑－１－基）苯基）－２，２，２－三氟乙氧）－嘧啶－４－基）苯基）丙酸乙酯之固體形式與其使用方法 |
| KR101706391B1 (ko) * | 2008-04-21 | 2017-02-13 | 렉시컨 파마슈티컬스 인코퍼레이티드 | Ｌｉｍｋ2 억제제, 그를 포함하는 조성물 및 그의 사용 방법 |
-
2011
- 2011-11-01 TW TW100139812A patent/TW201302754A/zh unknown
- 2011-11-03 US US13/288,321 patent/US8735408B2/en active Active
- 2011-11-03 RU RU2013125755/04A patent/RU2013125755A/ru not_active Application Discontinuation
- 2011-11-03 JP JP2013537811A patent/JP2013541588A/ja active Pending
- 2011-11-03 KR KR1020137014386A patent/KR20140003433A/ko not_active Withdrawn
- 2011-11-03 MX MX2013004923A patent/MX2013004923A/es not_active Application Discontinuation
- 2011-11-03 WO PCT/US2011/059086 patent/WO2012061565A1/en not_active Ceased
- 2011-11-03 SG SG2013033618A patent/SG190098A1/en unknown
- 2011-11-03 AU AU2011323371A patent/AU2011323371A1/en not_active Abandoned
- 2011-11-03 CN CN2011800533551A patent/CN103298815A/zh active Pending
- 2011-11-03 CA CA2817112A patent/CA2817112A1/en not_active Abandoned
- 2011-11-03 EP EP11785536.1A patent/EP2635584A1/en not_active Withdrawn
- 2011-11-03 BR BR112013011094A patent/BR112013011094A2/pt not_active IP Right Cessation
- 2011-11-04 AR ARP110104111A patent/AR083756A1/es unknown
-
2013
- 2013-04-22 IL IL225884A patent/IL225884A0/en unknown
- 2013-04-24 ZA ZA2013/02996A patent/ZA201302996B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012061565A1 (en) | 2012-05-10 |
| RU2013125755A (ru) | 2014-12-10 |
| AU2011323371A1 (en) | 2013-05-23 |
| CN103298815A (zh) | 2013-09-11 |
| SG190098A1 (en) | 2013-06-28 |
| US8735408B2 (en) | 2014-05-27 |
| ZA201302996B (en) | 2014-06-25 |
| BR112013011094A2 (pt) | 2016-08-23 |
| CA2817112A1 (en) | 2011-11-05 |
| JP2013541588A (ja) | 2013-11-14 |
| EP2635584A1 (en) | 2013-09-11 |
| TW201302754A (zh) | 2013-01-16 |
| US20120122898A1 (en) | 2012-05-17 |
| IL225884A0 (en) | 2013-07-31 |
| KR20140003433A (ko) | 2014-01-09 |
| MX2013004923A (es) | 2013-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |