AR079093A1 - Derivados de fenil(oxi/tio)alcanol, procedimiento para combatir hongos y procedimiento de preparacion de los mismos - Google Patents

Derivados de fenil(oxi/tio)alcanol, procedimiento para combatir hongos y procedimiento de preparacion de los mismos

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Publication number
AR079093A1
AR079093A1 ARP100102400A ARP100102400A AR079093A1 AR 079093 A1 AR079093 A1 AR 079093A1 AR P100102400 A ARP100102400 A AR P100102400A AR P100102400 A ARP100102400 A AR P100102400A AR 079093 A1 AR079093 A1 AR 079093A1
Authority
AR
Argentina
Prior art keywords
formula
ylmethyl
thio
meanings given
triazol
Prior art date
Application number
ARP100102400A
Other languages
English (en)
Inventor
Isolde Hauser-Hahn
Gorka Peris
Juergen Benting
Christian Paulitz
Joerg Nico Greul
Thomas Knobloch
Wachendorff-Neumann Ulrike Dr
Carl Friedrich Nising
Meissner Ruth Dr
Dirk Schmutzler
Ines Heinemann
Hendrik Helmke
Peter Dahmen
Christoph Andreas Braun
Klaus Kunz
Tomoki Tsuchiya
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of AR079093A1 publication Critical patent/AR079093A1/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/541,3-Diazines; Hydrogenated 1,3-diazines
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647Triazoles; Hydrogenated triazoles
    • A01N43/6531,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/24Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/22Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32Sulfur atoms
    • C07D213/34Sulfur atoms to which a second hetero atom is attached
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • CCHEMISTRY; METALLURGY
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    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
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    • C07D303/34Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms
    • CCHEMISTRY; METALLURGY
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    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Epoxy Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Reivindicacion 1: Derivados de fenil(oxi/tio)alcanol de la formula (1) en la que X representa 5-pirimidinilo, 1 H-1,2,4-triazol-1-ilmetilo, 3-piridinilo, 1 H-1,3-imidazol-1-ilmetilo o 2,4-dihidro-3H-1,2,4-triazol-3-tion-1-ilmetilo, Y representa O, S, SO, SO2 o CH2, Z representa bromo o yodo, R representa terc-butilo, isopropilo, 1-halociclopropilo, 1-(alquil C1-4)ciclopropilo, 1-(alcoxi C1-4)ciclopropilo o 1-((alquil C1-4)-tio)ciclo propilo, y las sales agroquímicamente activas de los mismos, excepto para los compuestos 1-(4-bromofenoxi)-3,3-dimetil-2-(piridin-3-il)butan-2-ol, 1-(4-bromofeniltio)-3,3-dimetil-2-(piridin-3-il)butan-2-ol, 1-(4-bromofeniltio)-3-metil-2-(piridin-3-il)butan-2-ol, 2-(4-bromofenoxi)-1-(1-clorociclopropil)-1-(piridin-3-iI)etanol, 1-(4-bromofenoxi)-3,3-dimetil-2-(1H-1,2,4-triazol-1-ilmetil)butan-2-ol, 1-(4-bromofenil)-4,4-dimetil-3-(1H-1,2,4-triazol-1-ilmetil)pentan-3-ol, 4-(4-bromofenil)-2-(1-metilciclopropil)-1-(1H-1,2,4-triazol-1-il)butan-2-ol, 4-(4-bromofenil)-2-(1-clorociclopropil)-1-(1H-1,2,4-triazol-1-il)butan-2-ol. Reivindicacion 6: Procedimiento para combatir hongos fitopatogenos perjudiciales, caracterizado porque los derivados de fenil(oxi/tio)alcanol de la formula (1) de acuerdo con la reivindicacion 1 o 2 se aplican a los hongos fitopatogenos perjudiciales y/o su hábitat. Reivindicacion 10: Procedimiento para preparar derivados de fenil(oxi/tio)alcanol de la formula (1) de acuerdo con la reivindicacion 1 o 2, caracterizado porque (A) si X1 representa 1 H-1,2,4-triazol-1-ilmetilo o 1 H-1,3-imidazol-1-ilmetilo, derivados de oxirano de la formula (2) en la que Y, Z y R tienen los significados dados en la reivindicacion 1, se hacen reaccionar con 1,2,4-triazol o 1,3-imidazol de la formula (3) en la que A representa CH o N, en presencia de un diluyente; o (B) si X2 representa 1H-1,2,4-triazol-1-ilmetilo, 1H-1,3-imidazol-1-ilmetilo, 5-pirimidinilo o 3-piridinilo, derivados de oxirano reactivos de la formula (4) en la que R tiene los significados dados en la reivindicacion 1, se hacen reaccionar con un (tio)fenol de la formula (5) en la que Y y Z tienen los significados dados en la reivindicacion 1 en presencia de un diluyente; o (C) si X3 representa 5-pirimidinilo o 3-piridinilo, fenil(oxi/tio)cetonas de la formula (6) en la que Y, Z y R tienen los significados dados en la reivindicacion 1, se hacen reaccionar con un haluro de la formula (7) Hal-X3 en la que Hal representa halogeno, en presencia de un diluyente y en presencia de un compuesto orgánico de metal alcalino; o (D) si X4 representa 5-pirimidinilo o 3-piridinilo, en una primera etapa, bromuros de la formula (8) se hacen reaccionar con un (tio)fenol de la formula (5) en la que Y y Z tienen los significados dados en la reivindicacion 1 en presencia de un diluyente y las fenil(oxi/tio)cetonas de la formula (9) obtenidas de este modo en la que Y y Z tienen los significados dados en la reivindicacion 1, se hacen reaccionar en una segunda etapa con compuestos organometálicos de la formula (10) R-M en la que R tiene los significados dados en la reivindicacion 1 y M representa metal, en presencia de un diluyente y en presencia de un compuesto orgánico de metal alcalino; o (E) derivados de fenil(oxi/tio)alcanol de la formula (1-c) en la que Y, Z y R tienen los significados dados anteriormente, se hacen reaccionar con azufre.
ARP100102400A 2009-07-08 2010-07-05 Derivados de fenil(oxi/tio)alcanol, procedimiento para combatir hongos y procedimiento de preparacion de los mismos AR079093A1 (es)

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Application Number Priority Date Filing Date Title
EP09164928 2009-07-08

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AR079093A1 true AR079093A1 (es) 2011-12-28

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US (2) US9051277B2 (es)
EP (1) EP2451784A1 (es)
JP (2) JP5792163B2 (es)
KR (1) KR20120046235A (es)
CN (2) CN104262272A (es)
AR (1) AR079093A1 (es)
AU (1) AU2010268837B2 (es)
BR (1) BR112012000245A8 (es)
CA (1) CA2767385A1 (es)
CL (1) CL2012000017A1 (es)
CO (1) CO6612220A2 (es)
EA (2) EA201590002A1 (es)
EC (1) ECSP12011575A (es)
MX (1) MX2012000279A (es)
TW (1) TWI519522B (es)
WO (1) WO2011003527A1 (es)

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KR20120046242A (ko) * 2009-07-08 2012-05-09 바이엘 크롭사이언스 아게 치환된 페닐(옥시/티오)알칸올 유도체
KR20120046235A (ko) * 2009-07-08 2012-05-09 바이엘 크롭사이언스 아게 페닐(옥시/티오)알칸올 유도체
RU2767635C1 (ru) * 2021-06-29 2022-03-18 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Комплексный препарат для предпосевной обработки семян яровой пшеницы на основе гиббереллинов, полиэтиленгликоля и фруктозы
CN116063226B (zh) * 2023-03-15 2023-06-02 云南省农业科学院茶叶研究所 含单萜酚结构的醚类化合物

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CN104262272A (zh) 2015-01-07
WO2011003527A1 (de) 2011-01-13
EA201270136A1 (ru) 2012-07-30
AU2010268837A1 (en) 2012-02-02
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US20140357649A1 (en) 2014-12-04
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EP2451784A1 (de) 2012-05-16
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