AR074881A1 - Un proceso para purificar una mezcla de polimeros - Google Patents
Un proceso para purificar una mezcla de polimerosInfo
- Publication number
- AR074881A1 AR074881A1 ARP090105080A ARP090105080A AR074881A1 AR 074881 A1 AR074881 A1 AR 074881A1 AR P090105080 A ARP090105080 A AR P090105080A AR P090105080 A ARP090105080 A AR P090105080A AR 074881 A1 AR074881 A1 AR 074881A1
- Authority
- AR
- Argentina
- Prior art keywords
- ultrafiltration
- acid
- purify
- polymers
- mixture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
- C08G69/10—Alpha-amino-carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Gastroenterology & Hepatology (AREA)
- Polymers & Plastics (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
Un proceso de purificación de péptidos copoliméricos, tal como polipéptidos COP-1 (copolímero-1), por ultrafiltración puede ser reformado por tratamiento de la solución de polipéptidos con un ácido antes de, o durante las etapas tempranas de la ultrafiltración. Por adición de ácido y/o la formación de sales de adición ácidas del polipéptido antes que se lleve a cabo la ultrafiltración se logra una ultrafiltración más rápida. Del mismo modo, adicionar el ácido durante el proceso de ultrafiltración pero antes de que ocurra la precipitación o amontonamiento de polipéptidos, puede también variar la eficiencia/conveniencia del paso de ultrafiltración.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14075108P | 2008-12-24 | 2008-12-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR074881A1 true AR074881A1 (es) | 2011-02-16 |
Family
ID=41795365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP090105080A AR074881A1 (es) | 2008-12-24 | 2009-12-23 | Un proceso para purificar una mezcla de polimeros |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9617313B2 (es) |
| EP (2) | EP2382233B1 (es) |
| KR (1) | KR20110112366A (es) |
| AR (1) | AR074881A1 (es) |
| AU (1) | AU2009331841A1 (es) |
| BR (1) | BRPI0922337A2 (es) |
| CL (1) | CL2011001565A1 (es) |
| CO (1) | CO6382160A2 (es) |
| EA (1) | EA019910B1 (es) |
| EC (1) | ECSP11011187A (es) |
| ES (1) | ES2584529T3 (es) |
| HU (1) | HUE028250T2 (es) |
| MX (1) | MX338074B (es) |
| PL (1) | PL2382233T3 (es) |
| PT (1) | PT2382233T (es) |
| WO (1) | WO2010072418A1 (es) |
| ZA (1) | ZA201104565B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2307448T3 (pl) * | 2008-08-07 | 2015-10-30 | Sigma Aldrich Co Llc | Wytwarzanie polilizyny i poliornityny o małym ciężarze cząsteczkowym z wysoką wydajnością |
| US8575198B1 (en) | 2011-09-07 | 2013-11-05 | Momenta Pharmaceuticals, Inc. | In-process control for the manufacture of glatiramer acetate |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2657972A (en) * | 1952-09-06 | 1953-11-03 | Robert B Woodward | Copolymer of l-leucine and dl-phenylalanine |
| IL36670A (en) * | 1971-04-21 | 1974-09-10 | Sela M | Therapeutic basic copolymers of amino acids |
| FR2182667B1 (es) * | 1972-05-03 | 1978-03-03 | Rhone Poulenc Ind | |
| CA2009996A1 (en) | 1989-02-17 | 1990-08-17 | Kathleen S. Cook | Process for making genes encoding random polymers of amino acids |
| US5800808A (en) * | 1994-05-24 | 1998-09-01 | Veda Research And Development Co., Ltd. | Copolymer-1 improvements in compositions of copolymers |
| EP1797109B1 (en) * | 2004-09-09 | 2016-02-24 | Yeda Research And Development Co., Ltd. | Mixtures of polypeptides, compositions containing and processes for preparing same, and uses thereof |
| JP5297653B2 (ja) | 2004-10-29 | 2013-09-25 | サンド・アクチエンゲゼルシヤフト | グラチラマーの製造法 |
| UA93669C2 (ru) | 2005-02-02 | 2011-03-10 | Тева Фармасьютикл Индастриз, Лтд. | Способ приготовления полипептидной смеси c использованием гидрогенолиза |
| JP2009542864A (ja) * | 2006-07-05 | 2009-12-03 | モメンタ ファーマシューティカルズ インコーポレイテッド | コポリマー１の調製のための改良法 |
-
2009
- 2009-12-23 US US12/645,794 patent/US9617313B2/en active Active
- 2009-12-23 AR ARP090105080A patent/AR074881A1/es active IP Right Grant
- 2009-12-24 PT PT98011745T patent/PT2382233T/pt unknown
- 2009-12-24 EA EA201170881A patent/EA019910B1/ru not_active IP Right Cessation
- 2009-12-24 MX MX2011006677A patent/MX338074B/es active IP Right Grant
- 2009-12-24 EP EP09801174.5A patent/EP2382233B1/en active Active
- 2009-12-24 ES ES09801174.5T patent/ES2584529T3/es active Active
- 2009-12-24 PL PL09801174T patent/PL2382233T3/pl unknown
- 2009-12-24 AU AU2009331841A patent/AU2009331841A1/en not_active Abandoned
- 2009-12-24 HU HUE09801174A patent/HUE028250T2/en unknown
- 2009-12-24 KR KR1020117016881A patent/KR20110112366A/ko not_active Application Discontinuation
- 2009-12-24 WO PCT/EP2009/009272 patent/WO2010072418A1/en active Application Filing
- 2009-12-24 EP EP20140176933 patent/EP2796463A1/en not_active Withdrawn
- 2009-12-24 BR BRPI0922337A patent/BRPI0922337A2/pt not_active IP Right Cessation
-
2011
- 2011-06-21 ZA ZA2011/04565A patent/ZA201104565B/en unknown
- 2011-06-23 CL CL2011001565A patent/CL2011001565A1/es unknown
- 2011-06-29 CO CO11081451A patent/CO6382160A2/es not_active Application Discontinuation
- 2011-07-07 EC EC2011011187A patent/ECSP11011187A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0922337A2 (pt) | 2016-11-29 |
| CL2011001565A1 (es) | 2012-01-13 |
| MX338074B (es) | 2016-04-01 |
| HUE028250T2 (en) | 2016-12-28 |
| EP2796463A1 (en) | 2014-10-29 |
| WO2010072418A1 (en) | 2010-07-01 |
| ZA201104565B (en) | 2012-09-26 |
| ES2584529T3 (es) | 2016-09-28 |
| AU2009331841A1 (en) | 2011-07-07 |
| EP2382233A1 (en) | 2011-11-02 |
| ECSP11011187A (es) | 2011-08-31 |
| US9617313B2 (en) | 2017-04-11 |
| EA019910B1 (ru) | 2014-07-30 |
| CO6382160A2 (es) | 2012-02-15 |
| PT2382233T (pt) | 2016-08-08 |
| US20100160606A1 (en) | 2010-06-24 |
| MX2011006677A (es) | 2011-09-15 |
| PL2382233T3 (pl) | 2017-03-31 |
| KR20110112366A (ko) | 2011-10-12 |
| EP2382233B1 (en) | 2016-05-11 |
| EA201170881A1 (ru) | 2012-01-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |