EA201170881A1 - Способ очистки полимерной смеси - Google Patents
Способ очистки полимерной смесиInfo
- Publication number
- EA201170881A1 EA201170881A1 EA201170881A EA201170881A EA201170881A1 EA 201170881 A1 EA201170881 A1 EA 201170881A1 EA 201170881 A EA201170881 A EA 201170881A EA 201170881 A EA201170881 A EA 201170881A EA 201170881 A1 EA201170881 A1 EA 201170881A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- ultrafiltration
- acid
- polypeptide
- addition
- polymeric mixture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
- C08G69/10—Alpha-amino-carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Gastroenterology & Hepatology (AREA)
- Polymers & Plastics (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
Способ очистки сополимерных пептидов, таких как полипептиды СОП-I, в результате ультрафильтрации может быть улучшен в результате обработки раствора полипептида кислотой до или во время ранних ступеней ультрафильтрации. Добавление кислоты и/или получение кислотно-аддитивных солей полипептида до ультрафильтрации проводят для обеспечения более быстрой ультрафильтрации. Подобным образом добавление кислоты в способе ультрафильтрации, но до возникновения осаждения полипептида или закупоривания также может улучшить и эффективность/удобство стадии ультрафильтрации.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14075108P | 2008-12-24 | 2008-12-24 | |
PCT/EP2009/009272 WO2010072418A1 (en) | 2008-12-24 | 2009-12-24 | A process for purifying a polymer mixture |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201170881A1 true EA201170881A1 (ru) | 2012-01-30 |
EA019910B1 EA019910B1 (ru) | 2014-07-30 |
Family
ID=41795365
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201170881A EA019910B1 (ru) | 2008-12-24 | 2009-12-24 | Способ очистки полимерной смеси |
Country Status (17)
Country | Link |
---|---|
US (1) | US9617313B2 (ru) |
EP (2) | EP2796463A1 (ru) |
KR (1) | KR20110112366A (ru) |
AR (1) | AR074881A1 (ru) |
AU (1) | AU2009331841A1 (ru) |
BR (1) | BRPI0922337A2 (ru) |
CL (1) | CL2011001565A1 (ru) |
CO (1) | CO6382160A2 (ru) |
EA (1) | EA019910B1 (ru) |
EC (1) | ECSP11011187A (ru) |
ES (1) | ES2584529T3 (ru) |
HU (1) | HUE028250T2 (ru) |
MX (1) | MX338074B (ru) |
PL (1) | PL2382233T3 (ru) |
PT (1) | PT2382233T (ru) |
WO (1) | WO2010072418A1 (ru) |
ZA (1) | ZA201104565B (ru) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2307448T3 (pl) * | 2008-08-07 | 2015-10-30 | Sigma Aldrich Co Llc | Wytwarzanie polilizyny i poliornityny o małym ciężarze cząsteczkowym z wysoką wydajnością |
US8575198B1 (en) | 2011-09-07 | 2013-11-05 | Momenta Pharmaceuticals, Inc. | In-process control for the manufacture of glatiramer acetate |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2657972A (en) * | 1952-09-06 | 1953-11-03 | Robert B Woodward | Copolymer of l-leucine and dl-phenylalanine |
IL36670A (en) * | 1971-04-21 | 1974-09-10 | Sela M | Therapeutic basic copolymers of amino acids |
FR2182667B1 (ru) * | 1972-05-03 | 1978-03-03 | Rhone Poulenc Ind | |
CA2009996A1 (en) | 1989-02-17 | 1990-08-17 | Kathleen S. Cook | Process for making genes encoding random polymers of amino acids |
US5800808A (en) * | 1994-05-24 | 1998-09-01 | Veda Research And Development Co., Ltd. | Copolymer-1 improvements in compositions of copolymers |
WO2006029411A2 (en) * | 2004-09-09 | 2006-03-16 | Yeda Research And Development Co. Ltd. | Mixtures of polypeptides, compositions containing and processes for preparing same, and uses thereof |
AR052321A1 (es) * | 2004-10-29 | 2007-03-14 | Sandoz Ag | Procesos para la preparacion de un polipeptido |
US20060172942A1 (en) | 2005-02-02 | 2006-08-03 | Teva Pharmaceutical Industries, Ltd. | Process for producing polypeptide mixtures using hydrogenolysis |
AU2007269140A1 (en) * | 2006-07-05 | 2008-01-10 | Momenta Pharmaceuticals, Inc. | Improved process for the preparation of copolymer-1 |
-
2009
- 2009-12-23 US US12/645,794 patent/US9617313B2/en active Active
- 2009-12-23 AR ARP090105080A patent/AR074881A1/es active IP Right Grant
- 2009-12-24 MX MX2011006677A patent/MX338074B/es active IP Right Grant
- 2009-12-24 EA EA201170881A patent/EA019910B1/ru not_active IP Right Cessation
- 2009-12-24 AU AU2009331841A patent/AU2009331841A1/en not_active Abandoned
- 2009-12-24 EP EP20140176933 patent/EP2796463A1/en not_active Withdrawn
- 2009-12-24 ES ES09801174.5T patent/ES2584529T3/es active Active
- 2009-12-24 KR KR1020117016881A patent/KR20110112366A/ko not_active Application Discontinuation
- 2009-12-24 PT PT98011745T patent/PT2382233T/pt unknown
- 2009-12-24 WO PCT/EP2009/009272 patent/WO2010072418A1/en active Application Filing
- 2009-12-24 PL PL09801174T patent/PL2382233T3/pl unknown
- 2009-12-24 BR BRPI0922337A patent/BRPI0922337A2/pt not_active IP Right Cessation
- 2009-12-24 HU HUE09801174A patent/HUE028250T2/en unknown
- 2009-12-24 EP EP09801174.5A patent/EP2382233B1/en active Active
-
2011
- 2011-06-21 ZA ZA2011/04565A patent/ZA201104565B/en unknown
- 2011-06-23 CL CL2011001565A patent/CL2011001565A1/es unknown
- 2011-06-29 CO CO11081451A patent/CO6382160A2/es not_active Application Discontinuation
- 2011-07-07 EC EC2011011187A patent/ECSP11011187A/es unknown
Also Published As
Publication number | Publication date |
---|---|
ECSP11011187A (es) | 2011-08-31 |
US9617313B2 (en) | 2017-04-11 |
EP2382233A1 (en) | 2011-11-02 |
EP2382233B1 (en) | 2016-05-11 |
MX2011006677A (es) | 2011-09-15 |
AR074881A1 (es) | 2011-02-16 |
US20100160606A1 (en) | 2010-06-24 |
PL2382233T3 (pl) | 2017-03-31 |
CL2011001565A1 (es) | 2012-01-13 |
PT2382233T (pt) | 2016-08-08 |
AU2009331841A1 (en) | 2011-07-07 |
WO2010072418A1 (en) | 2010-07-01 |
KR20110112366A (ko) | 2011-10-12 |
ES2584529T3 (es) | 2016-09-28 |
MX338074B (es) | 2016-04-01 |
ZA201104565B (en) | 2012-09-26 |
EA019910B1 (ru) | 2014-07-30 |
CO6382160A2 (es) | 2012-02-15 |
BRPI0922337A2 (pt) | 2016-11-29 |
HUE028250T2 (en) | 2016-12-28 |
EP2796463A1 (en) | 2014-10-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM KG MD TJ TM |
|
QB4A | Registration of a licence in a contracting state | ||
QB4A | Registration of a licence in a contracting state | ||
TK4A | Corrections in published eurasian patents |