AR073112A1 - Produccion de aminoacidos azufrados n- acilados con actividad enzimatica n- aciltransferasa potenciada en microorganismos - Google Patents
Produccion de aminoacidos azufrados n- acilados con actividad enzimatica n- aciltransferasa potenciada en microorganismosInfo
- Publication number
- AR073112A1 AR073112A1 ARP090103229A ARP090103229A AR073112A1 AR 073112 A1 AR073112 A1 AR 073112A1 AR P090103229 A ARP090103229 A AR P090103229A AR P090103229 A ARP090103229 A AR P090103229A AR 073112 A1 AR073112 A1 AR 073112A1
- Authority
- AR
- Argentina
- Prior art keywords
- amino acids
- production
- microorganisms
- aciltranspherase
- acilated
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Polipéptido aislado con actividad L-aminoácido-N-acil transferasa y un microorganismo modificado en el que esta enzima se sobreexpresa. Los sustratos de dicha enzima incluyen principalmente metionina y sus derivados o análogos. La sobreexpresion en microorganismos productores de aminoácidos azufrados permite la produccion de mayores cantidades de aminoácidos azufrados n-acilados. También se reivindica el asilamiento de aminoácidos azufrados n-acilados a partir del medio de fermentacion.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2008/060999 WO2010020289A1 (en) | 2008-08-22 | 2008-08-22 | Production of n-acetylated sulphur-containing amino acids with microorganisms having enhanced n-acetyltransferase enzymatic activity |
US12/370,434 US8143031B2 (en) | 2008-08-22 | 2009-02-12 | Production of N-acylated sulphur-containing amino acids with microorganisms having enhanced N-acyltransferase enzymatic activity |
Publications (1)
Publication Number | Publication Date |
---|---|
AR073112A1 true AR073112A1 (es) | 2010-10-13 |
Family
ID=40364448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP090103229A AR073112A1 (es) | 2008-08-22 | 2009-08-21 | Produccion de aminoacidos azufrados n- acilados con actividad enzimatica n- aciltransferasa potenciada en microorganismos |
Country Status (8)
Country | Link |
---|---|
US (1) | US8143031B2 (es) |
JP (1) | JP2012500623A (es) |
KR (1) | KR20110042383A (es) |
CN (1) | CN102131923A (es) |
AR (1) | AR073112A1 (es) |
MX (1) | MX2011001961A (es) |
RU (1) | RU2011108706A (es) |
WO (2) | WO2010020289A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010020290A1 (en) * | 2008-08-22 | 2010-02-25 | Metabolic Explorer | Producing methionine without n-acetyl methionine |
BR112016027518A2 (pt) * | 2014-05-23 | 2018-01-30 | Evonik Degussa Gmbh | produção biossintética de acil-aminoácidos". |
KR101821050B1 (ko) * | 2015-10-14 | 2018-03-09 | 씨제이제일제당 (주) | 바이오-기반 n-아세틸-l-메티오닌 및 이의 용도 |
WO2017065567A1 (en) * | 2015-10-14 | 2017-04-20 | Cj Cheiljedang Corporation | Bio-based n-acetyl-l-methionine and use thereof |
KR101941745B1 (ko) * | 2016-07-20 | 2019-01-24 | 씨제이제일제당 (주) | 아실전이효소의 활성을 갖는 미생물 및 이의 용도 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2402285A1 (en) * | 2000-03-10 | 2001-09-27 | Trustees Of Tufts College | Nimr compositions and their methods of use |
JP4682454B2 (ja) | 2000-06-28 | 2011-05-11 | 味の素株式会社 | 新規変異型n−アセチルグルタミン酸合成酵素及びl−アルギニンの製造法 |
DE10144493A1 (de) | 2001-09-11 | 2003-07-03 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coyneformer Bakterien |
DE102004013503A1 (de) | 2004-03-18 | 2005-10-06 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
DE102004055414A1 (de) | 2004-11-17 | 2006-05-24 | Degussa Ag | Allele des metK-Gens aus coryneformen Bakterien |
US8389250B2 (en) | 2006-01-04 | 2013-03-05 | Metabolic Explorer | Methods for producing methionine by culturing a microorganism modified to enhance production of cysteine |
WO2009043372A1 (en) | 2007-10-02 | 2009-04-09 | Metabolic Explorer | Increasing methionine yield |
-
2008
- 2008-08-22 WO PCT/EP2008/060999 patent/WO2010020289A1/en active Application Filing
-
2009
- 2009-02-12 US US12/370,434 patent/US8143031B2/en not_active Expired - Fee Related
- 2009-08-21 WO PCT/EP2009/060812 patent/WO2010020682A1/en active Application Filing
- 2009-08-21 JP JP2011523427A patent/JP2012500623A/ja active Pending
- 2009-08-21 MX MX2011001961A patent/MX2011001961A/es unknown
- 2009-08-21 CN CN200980132546XA patent/CN102131923A/zh active Pending
- 2009-08-21 AR ARP090103229A patent/AR073112A1/es unknown
- 2009-08-21 KR KR1020117006416A patent/KR20110042383A/ko not_active Application Discontinuation
- 2009-08-21 RU RU2011108706/10A patent/RU2011108706A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
RU2011108706A (ru) | 2012-09-27 |
WO2010020289A1 (en) | 2010-02-25 |
CN102131923A (zh) | 2011-07-20 |
WO2010020682A1 (en) | 2010-02-25 |
KR20110042383A (ko) | 2011-04-26 |
US8143031B2 (en) | 2012-03-27 |
JP2012500623A (ja) | 2012-01-12 |
US20100047880A1 (en) | 2010-02-25 |
MX2011001961A (es) | 2011-03-21 |
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Legal Events
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FB | Suspension of granting procedure |