AR070737A1 - Proceso para la elaboracion de (fenilsulfanilfenil) piperidinas - Google Patents
Proceso para la elaboracion de (fenilsulfanilfenil) piperidinasInfo
- Publication number
- AR070737A1 AR070737A1 ARP090100734A ARP090100734A AR070737A1 AR 070737 A1 AR070737 A1 AR 070737A1 AR P090100734 A ARP090100734 A AR P090100734A AR P090100734 A ARP090100734 A AR P090100734A AR 070737 A1 AR070737 A1 AR 070737A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- compound
- alkyl
- acid addition
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 10
- 239000002253 acid Substances 0.000 abstract 5
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- SJZKULRDWHPHGG-UHFFFAOYSA-N 1-benzylpiperidin-4-one Chemical class C1CC(=O)CCN1CC1=CC=CC=C1 SJZKULRDWHPHGG-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical group C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200800314 | 2008-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR070737A1 true AR070737A1 (es) | 2010-04-28 |
Family
ID=40547924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP090100734A AR070737A1 (es) | 2008-03-03 | 2009-03-02 | Proceso para la elaboracion de (fenilsulfanilfenil) piperidinas |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US8362255B2 (https=) |
| EP (1) | EP2260024B1 (https=) |
| JP (1) | JP5564439B2 (https=) |
| KR (1) | KR20100122914A (https=) |
| CN (1) | CN101959859B (https=) |
| AR (1) | AR070737A1 (https=) |
| AT (1) | ATE539055T1 (https=) |
| AU (1) | AU2009221170B2 (https=) |
| BR (1) | BRPI0908166A2 (https=) |
| CA (1) | CA2715579A1 (https=) |
| CL (1) | CL2009000490A1 (https=) |
| CO (1) | CO6290758A2 (https=) |
| CY (1) | CY1113887T1 (https=) |
| DK (1) | DK2260024T3 (https=) |
| EA (1) | EA017855B1 (https=) |
| ES (1) | ES2377862T3 (https=) |
| HR (1) | HRP20120118T1 (https=) |
| IL (1) | IL207471A (https=) |
| MX (1) | MX2010008729A (https=) |
| NZ (1) | NZ587593A (https=) |
| PL (1) | PL2260024T3 (https=) |
| PT (1) | PT2260024E (https=) |
| RS (1) | RS52128B (https=) |
| SI (1) | SI2260024T1 (https=) |
| TW (1) | TW200940505A (https=) |
| UA (1) | UA98698C2 (https=) |
| WO (1) | WO2009109541A1 (https=) |
| ZA (1) | ZA201006135B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2656057C (en) * | 2006-06-16 | 2012-10-02 | H. Lundbeck A/S | Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain |
| JP2012163850A (ja) * | 2011-02-08 | 2012-08-30 | Nippon Sheet Glass Co Ltd | 正立等倍レンズアレイプレート、光走査ユニット、画像読取装置および画像書込装置 |
| US9173883B2 (en) | 2012-05-21 | 2015-11-03 | Novartis Ag | Ring-substituted N-pyridinyl amides as kinase inhibitors |
| CN104710345B (zh) * | 2013-12-17 | 2017-09-05 | 江苏恩华药业股份有限公司 | 用于制备4‑（2‑（4‑甲基苯基硫基））苯基哌啶的化合物、其制备方法及应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2324087A (en) * | 1997-04-10 | 1998-10-14 | Merck & Co Inc | Preparation of (S)-3-Carbethoxy-3-benzylpiperidine |
| AU1805701A (en) | 1999-12-20 | 2001-07-03 | Eli Lilly And Company | A process for preparing trans-2,4-disubstituted piperidines |
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| UA81300C2 (en) * | 2003-04-04 | 2007-12-25 | Lundbeck & Co As H | Derivates of 4-(2-fenilsulfanilfenil)-1,2,3,6-tetrahydropiridin as retarding agents of serotonin recapture |
| WO2004087156A1 (en) * | 2003-04-04 | 2004-10-14 | H. Lundbeck A/S | 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors |
| CA2656057C (en) * | 2006-06-16 | 2012-10-02 | H. Lundbeck A/S | Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain |
-
2009
- 2009-02-03 UA UAA201011031A patent/UA98698C2/ru unknown
- 2009-02-19 TW TW098105235A patent/TW200940505A/zh unknown
- 2009-03-02 EP EP09717792A patent/EP2260024B1/en active Active
- 2009-03-02 PT PT09717792T patent/PT2260024E/pt unknown
- 2009-03-02 AT AT09717792T patent/ATE539055T1/de active
- 2009-03-02 NZ NZ587593A patent/NZ587593A/en not_active IP Right Cessation
- 2009-03-02 HR HR20120118T patent/HRP20120118T1/hr unknown
- 2009-03-02 CL CL2009000490A patent/CL2009000490A1/es unknown
- 2009-03-02 AU AU2009221170A patent/AU2009221170B2/en not_active Ceased
- 2009-03-02 MX MX2010008729A patent/MX2010008729A/es active IP Right Grant
- 2009-03-02 KR KR1020107019480A patent/KR20100122914A/ko not_active Ceased
- 2009-03-02 AR ARP090100734A patent/AR070737A1/es unknown
- 2009-03-02 RS RS20120063A patent/RS52128B/sr unknown
- 2009-03-02 ES ES09717792T patent/ES2377862T3/es active Active
- 2009-03-02 EA EA201071025A patent/EA017855B1/ru not_active IP Right Cessation
- 2009-03-02 PL PL09717792T patent/PL2260024T3/pl unknown
- 2009-03-02 JP JP2010549114A patent/JP5564439B2/ja not_active Expired - Fee Related
- 2009-03-02 WO PCT/EP2009/052440 patent/WO2009109541A1/en not_active Ceased
- 2009-03-02 CN CN200980108235XA patent/CN101959859B/zh not_active Expired - Fee Related
- 2009-03-02 BR BRPI0908166-6A patent/BRPI0908166A2/pt not_active IP Right Cessation
- 2009-03-02 DK DK09717792.7T patent/DK2260024T3/da active
- 2009-03-02 CA CA2715579A patent/CA2715579A1/en not_active Abandoned
- 2009-03-02 US US12/920,357 patent/US8362255B2/en not_active Expired - Fee Related
- 2009-03-02 SI SI200930184T patent/SI2260024T1/sl unknown
-
2010
- 2010-08-08 IL IL207471A patent/IL207471A/en not_active IP Right Cessation
- 2010-08-27 ZA ZA2010/06135A patent/ZA201006135B/en unknown
- 2010-09-02 CO CO10108740A patent/CO6290758A2/es active IP Right Grant
-
2012
- 2012-02-13 CY CY20121100145T patent/CY1113887T1/el unknown
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| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |