AR059710A1 - Arilsulfonamidas sustituidas - Google Patents

Arilsulfonamidas sustituidas

Info

Publication number
AR059710A1
AR059710A1 ARP070100858A ARP070100858A AR059710A1 AR 059710 A1 AR059710 A1 AR 059710A1 AR P070100858 A ARP070100858 A AR P070100858A AR P070100858 A ARP070100858 A AR P070100858A AR 059710 A1 AR059710 A1 AR 059710A1
Authority
AR
Argentina
Prior art keywords
halogen
represents hydrogen
hydrogen
arilsulphonamids
substituted
Prior art date
Application number
ARP070100858A
Other languages
English (en)
Inventor
Niels Svenstrup
Bernd Riedl
Dieter Lang
Rudolf Schohe-Loop
Andreas Goller
Tobias Wunberg
Daniela Paulsen
Dirk Heimbach
Holger Zimmermann
Daniela Henninger
Joachim Schuhmacher
Dagmar Karthaus
Original Assignee
Aicuris Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38180640&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR059710(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aicuris Gmbh & Co Kg filed Critical Aicuris Gmbh & Co Kg
Publication of AR059710A1 publication Critical patent/AR059710A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Arilsulfonamidas, proceso para su preparacion y su utilizacion para la produccion de medicamentos para el tratamiento y/o la profilaxis de enfermedades, especialmente para su utilizacion como agentes antivirales, particularmente contra los citomegalovirus. Reivindicacion 1: Compuesto caracterizado porque responde a la formula (1) donde A representa un grupo de formulas (2) donde * es el sitio de union con el átomo de carbono del anillo piridinilo y es el sitio de union con el átomo de carbono del anillo fenilo, R1 representa hidrogeno, amino o metilcarbonilamino, R2 representa hidrogeno o halogeno, R3 representa hidrogeno, halogeno o ciano, R4 representa hidrogeno, halogeno o ciano, R5 representa hidrogeno, o halogeno, R6 representa hidrogeno, o halogeno, R7 hidrogeno, halogeno o alquilo C1-3, R8 representa hidrogeno, halogeno o alquilo C1-3, o una de sus sales, sus solvatos o los solvatos de sus sales.
ARP070100858A 2006-03-03 2007-03-02 Arilsulfonamidas sustituidas AR059710A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102006009928A DE102006009928A1 (de) 2006-03-03 2006-03-03 Substituierte Arylsulfonamide

Publications (1)

Publication Number Publication Date
AR059710A1 true AR059710A1 (es) 2008-04-23

Family

ID=38180640

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070100858A AR059710A1 (es) 2006-03-03 2007-03-02 Arilsulfonamidas sustituidas

Country Status (26)

Country Link
US (1) US8318761B2 (es)
EP (1) EP1991529B1 (es)
JP (1) JP5255455B2 (es)
KR (1) KR101447758B1 (es)
CN (1) CN101389607B (es)
AR (1) AR059710A1 (es)
AT (1) ATE451356T1 (es)
AU (1) AU2007222689B2 (es)
BR (1) BRPI0707068A2 (es)
CA (1) CA2642602C (es)
DE (2) DE102006009928A1 (es)
DK (1) DK1991529T3 (es)
ES (1) ES2335316T3 (es)
HK (1) HK1125371A1 (es)
IL (1) IL193449A (es)
JO (1) JO2581B1 (es)
MX (1) MX2008011264A (es)
PE (1) PE20080136A1 (es)
PL (1) PL1991529T3 (es)
PT (1) PT1991529E (es)
RU (1) RU2423352C2 (es)
TW (1) TWI388559B (es)
UA (1) UA95103C2 (es)
UY (1) UY30178A1 (es)
WO (1) WO2007101573A1 (es)
ZA (1) ZA200807189B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10319612A1 (de) 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
EP2103638A1 (de) * 2008-03-20 2009-09-23 Bayer MaterialScience AG Hydrophile Polyurethanlösungen
EP2103316A1 (de) * 2008-03-20 2009-09-23 Bayer MaterialScience AG Hydrophile Polyurethandispersionen
EP2103317A1 (de) * 2008-03-20 2009-09-23 Bayer MaterialScience AG Medizinische Geräte mit hydrophilen Beschichtungen
EP2103318A1 (de) * 2008-03-20 2009-09-23 Bayer MaterialScience AG Medizinische Geräte mit hydrophilen Beschichtungen
DE102008025614A1 (de) * 2008-05-28 2009-12-03 Bayer Materialscience Ag Hydrophile Polyurethanbeschichtungen
DE102008025613A1 (de) * 2008-05-28 2009-12-03 Bayer Materialscience Ag Hydrophile Polyurethanbeschichtungen
ES2380785T3 (es) 2008-09-04 2012-05-18 Bayer Materialscience Ag Dispersiones de poliuretanos hidrófilas basadas en TCD
DE102011101446A1 (de) 2011-05-10 2012-11-15 Aicuris Gmbh & Co. Kg Herstellung von "Dense Bodies" (DB)
EP2853532B1 (en) * 2013-09-28 2020-12-09 Instytut Farmakologii Polskiej Akademii Nauk 1,2,4-oxadiazole derivatives as allosteric modulators of metabotropic glutamate receptors belonging to group III
CN109879817B (zh) * 2019-03-19 2020-10-02 扬州大学 甲基二磺隆的制备方法
RU2738848C1 (ru) * 2019-10-24 2020-12-17 Общество с ограниченной ответственностью "Научно-исследовательский институт ХимРар" (ООО "НИИ ХимРар") Ингибитор вируса гепатита В (ВГВ), представляющий собой производные N-{ 3-[6-(диалкиламино)пиридазин-3-ил]фенил} арилсульфонамида и производные N-{ 4-[6-(диалкиламино)пиридазин-3-ил]фенил} арилсульфонамида

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19802437A1 (de) 1998-01-23 1999-07-29 Bayer Ag Verwendung von substituierten Sulfonamiden als anitvirale Mittel und neue Stoffe
CN1347411A (zh) 1999-04-19 2002-05-01 盐野义制药株式会社 含有噁二唑环的磺酰胺衍生物
DE19920790A1 (de) * 1999-05-06 2000-11-09 Bayer Ag Bis-Sulfonamide mit anti-HCMV-Wirkung
DE19930075A1 (de) 1999-06-30 2001-01-04 Bayer Ag Neue Amino- und Amidosulfonamide als antivirale Mittel
RU2003133750A (ru) * 2001-04-19 2005-05-10 Байер АГ (DE) Арилсульфонамиды в качестве антивирусных агентов
DE10138578A1 (de) * 2001-08-06 2003-02-27 Bayer Ag Heterocyclylarylsulfonamide

Also Published As

Publication number Publication date
BRPI0707068A2 (pt) 2011-04-19
WO2007101573A1 (de) 2007-09-13
PE20080136A1 (es) 2008-04-18
JP2009529016A (ja) 2009-08-13
US20090176842A1 (en) 2009-07-09
AU2007222689A1 (en) 2007-09-13
ATE451356T1 (de) 2009-12-15
UY30178A1 (es) 2007-09-28
IL193449A (en) 2013-02-28
US8318761B2 (en) 2012-11-27
RU2008139195A (ru) 2010-04-10
PT1991529E (pt) 2010-01-06
CN101389607B (zh) 2011-09-07
ZA200807189B (en) 2009-12-30
DE102006009928A1 (de) 2007-09-06
CA2642602C (en) 2014-05-13
RU2423352C2 (ru) 2011-07-10
DK1991529T3 (da) 2010-04-12
UA95103C2 (ru) 2011-07-11
JP5255455B2 (ja) 2013-08-07
TWI388559B (zh) 2013-03-11
KR20080107456A (ko) 2008-12-10
PL1991529T3 (pl) 2010-05-31
ES2335316T3 (es) 2010-03-24
EP1991529A1 (de) 2008-11-19
TW200813034A (en) 2008-03-16
EP1991529B1 (de) 2009-12-09
HK1125371A1 (en) 2009-08-07
AU2007222689B2 (en) 2011-11-17
MX2008011264A (es) 2008-09-12
KR101447758B1 (ko) 2014-10-06
CA2642602A1 (en) 2007-09-13
IL193449A0 (en) 2009-05-04
DE502007002264D1 (de) 2010-01-21
CN101389607A (zh) 2009-03-18
JO2581B1 (en) 2011-02-27

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