AR058212A1 - Formas novedosas de acido (r-(r*, r* ))-2-(4-fluorofenil) - beta , delta- dihidroxi -5- (1- metiletil) -3-fenil-4- ( fenilamino) carbonil)-1h- pirrol -1- heptanoico magnesio - Google Patents

Formas novedosas de acido (r-(r*, r* ))-2-(4-fluorofenil) - beta , delta- dihidroxi -5- (1- metiletil) -3-fenil-4- ( fenilamino) carbonil)-1h- pirrol -1- heptanoico magnesio

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Publication number
AR058212A1
AR058212A1 ARP060105094A ARP060105094A AR058212A1 AR 058212 A1 AR058212 A1 AR 058212A1 AR P060105094 A ARP060105094 A AR P060105094A AR P060105094 A ARP060105094 A AR P060105094A AR 058212 A1 AR058212 A1 AR 058212A1
Authority
AR
Argentina
Prior art keywords
methylety
heptanoico
fluorophenil
dihydroxi
pirrol
Prior art date
Application number
ARP060105094A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37836758&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR058212(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR058212A1 publication Critical patent/AR058212A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Se describen formas novedosas de sal magnesio de atorvastatina denominadas Forma A, Forma B, Forma C, Forma D, Forma E y Forma F, composiciones farmacéuticas que contienen tales compuestos, procedimientos para su preparacion y procedimientos que utilizan los compuestos para el tratamiento de hiperlipidemia, hipercolesterolemia, osteoporosis, hiperplasia prostática benigna (HPB) y enfermedad de Alzheimer. Reivindicacion 1: Una atorvastatina magnesio Forma A que tiene una difraccion de cristales finos por rayos X que contiene los siguientes valores de 2? medidos usando radiacion CuKalfa:9,3, 14,3 y 18,4.
ARP060105094A 2005-11-21 2006-11-21 Formas novedosas de acido (r-(r*, r* ))-2-(4-fluorofenil) - beta , delta- dihidroxi -5- (1- metiletil) -3-fenil-4- ( fenilamino) carbonil)-1h- pirrol -1- heptanoico magnesio AR058212A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73844705P 2005-11-21 2005-11-21

Publications (1)

Publication Number Publication Date
AR058212A1 true AR058212A1 (es) 2008-01-23

Family

ID=37836758

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060105094A AR058212A1 (es) 2005-11-21 2006-11-21 Formas novedosas de acido (r-(r*, r* ))-2-(4-fluorofenil) - beta , delta- dihidroxi -5- (1- metiletil) -3-fenil-4- ( fenilamino) carbonil)-1h- pirrol -1- heptanoico magnesio

Country Status (10)

Country Link
US (3) US8084488B2 (es)
JP (1) JP2007137885A (es)
AR (1) AR058212A1 (es)
AT (1) ATE466840T1 (es)
DE (1) DE602006014193D1 (es)
DK (1) DK1957452T3 (es)
ES (1) ES2304335T3 (es)
PT (1) PT1957452E (es)
TW (1) TW200738624A (es)
WO (1) WO2007057755A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100222405A1 (en) * 2005-05-03 2010-09-02 Yatendar Kumar Magnesium salts of hmg-coa reductase inhibitors
US20100168201A1 (en) * 2005-11-29 2010-07-01 Biocan Limited Polymorphs of [R-(R*, R*) ]-2-(4-Fluorophenyl)-Beta, Delta-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)Carbonyl]-1H-Pyrrole-1-Heptanoic Acid Magnesium Salt (2:1)
SI22255A (sl) * 2006-04-14 2007-10-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Novi polimorfi statinovih soli in njihova uporabav farmacevtskih formulacijah
KR20090128423A (ko) * 2007-04-13 2009-12-15 니콕스 에스. 에이. 아토르바스타틴 4-(니트록시)부틸 에스테르의 결정형
WO2009063476A1 (en) * 2007-11-16 2009-05-22 Biocon Limited A crystalline form of atorvastatin hemi magnesium salt and a process thereof
EP2130819A3 (en) 2008-04-10 2009-12-23 Ranbaxy Laboratories Limited Crystalline forms of atorvastatin magnesium
WO2009157005A1 (en) * 2008-06-26 2009-12-30 Biocon Limited Crystalline forms of atorvastatin hemi-magnesium salt and a process thereof

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Also Published As

Publication number Publication date
US20120059040A1 (en) 2012-03-08
PT1957452E (pt) 2010-05-25
US8383667B2 (en) 2013-02-26
JP2007137885A (ja) 2007-06-07
US8648109B2 (en) 2014-02-11
ES2304335T3 (es) 2010-05-19
WO2007057755A1 (en) 2007-05-24
DK1957452T3 (da) 2010-07-26
US8084488B2 (en) 2011-12-27
ATE466840T1 (de) 2010-05-15
US20130131138A1 (en) 2013-05-23
US20100069459A1 (en) 2010-03-18
TW200738624A (en) 2007-10-16
DE602006014193D1 (de) 2010-06-17
ES2304335T1 (es) 2008-10-16

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