AR056847A1 - Método para purificar la fsh o mutaciones de la fsh - Google Patents

Método para purificar la fsh o mutaciones de la fsh

Info

Publication number
AR056847A1
AR056847A1 ARP060105420A ARP060105420A AR056847A1 AR 056847 A1 AR056847 A1 AR 056847A1 AR P060105420 A ARP060105420 A AR P060105420A AR P060105420 A ARP060105420 A AR P060105420A AR 056847 A1 AR056847 A1 AR 056847A1
Authority
AR
Argentina
Prior art keywords
fsh
mutations
purifying
chromatography
anion exchange
Prior art date
Application number
ARP060105420A
Other languages
English (en)
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of AR056847A1 publication Critical patent/AR056847A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invencion se relaciona con un método para purificar glicoproteínas, preferentemente la FSH o las mutaciones de la FSH, incluyendo los pasos de someter un líquido que contenga dicha la FSH o la mutacion de la FSH a: (1) cromatografía de afinidad de tenido; (2) cromatografía de intercambio anion débil; (3) cromatografía de interaccion hidrofobica; y (4) cromatografía de intercambio anion fuerte; los cuales pueden efectuarse en cualquier orden.
ARP060105420A 2005-12-09 2006-12-07 Método para purificar la fsh o mutaciones de la fsh AR056847A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05111917 2005-12-09
EP05111915 2005-12-09
US83575406P 2006-08-04 2006-08-04

Publications (1)

Publication Number Publication Date
AR056847A1 true AR056847A1 (es) 2007-10-24

Family

ID=37671008

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060105420A AR056847A1 (es) 2005-12-09 2006-12-07 Método para purificar la fsh o mutaciones de la fsh

Country Status (8)

Country Link
US (1) US8604175B2 (es)
EP (1) EP1960419B1 (es)
JP (1) JP5199112B2 (es)
AR (1) AR056847A1 (es)
AU (1) AU2006323925B2 (es)
CA (1) CA2625978A1 (es)
IL (1) IL191619A0 (es)
WO (1) WO2007065918A2 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS57549B1 (sr) * 2005-08-26 2018-10-31 Ares Trading Sa Proces za pripremu glikoziliranog interferona beta
ZA200805194B (en) * 2006-01-17 2009-10-28 Serono Lab Novel FSH glycosylation variant D3N
US8455513B2 (en) 2007-01-10 2013-06-04 Aerie Pharmaceuticals, Inc. 6-aminoisoquinoline compounds
WO2009053360A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying an fc-containing protein
CA2702448A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying fc-fusion proteins
JP2009273427A (ja) * 2008-05-16 2009-11-26 Jcr Pharmaceuticals Co Ltd 組換え体ヒトｆｓｈの製造方法
CN101347613B (zh) * 2008-09-17 2011-10-26 上海天伟生物制药有限公司 几乎不含亚基的糖蛋白的组合物及其制备方法
KR101761168B1 (ko) * 2009-04-01 2017-07-25 바이오제너릭스 게엠베하 재조합 ｆｓｈ 정제 방법
DE102009032179A1 (de) * 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta
EP2325194A1 (en) 2009-11-24 2011-05-25 Glycotope GmbH Process for the purification of glycoproteins
JP2014503495A (ja) * 2010-11-15 2014-02-13 バイオジェン アイデック インコーポレイテッド 過負荷結合および溶出クロマトグラフィによる選択生成物アイソフォームの富化および濃縮
JP2011172602A (ja) * 2011-06-15 2011-09-08 Jcr Pharmaceuticals Co Ltd 組換え体ヒトｆｓｈの製造方法
WO2014183175A1 (en) * 2013-05-16 2014-11-20 Universidade De São Paulo Methods for production and/or purification of hormones
JP5750471B2 (ja) * 2013-05-22 2015-07-22 Ｊｃｒファーマ株式会社 組換え体ヒトｆｓｈの製造方法
EP3110839B1 (en) * 2014-02-24 2018-05-16 Altergon S.a. Extraction process to obtain hcg having a high biological activity
CA2945591A1 (en) * 2014-04-18 2015-10-22 Cadila Healthcare Limited Novel purification process of gonadotropin
CN113372433B (zh) * 2021-03-12 2022-10-11 上海景泽生物技术有限公司 纯化fsh方法

Family Cites Families (40)

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CH648331A5 (de) 1979-07-31 1985-03-15 Hoffmann La Roche Homogenes fibroblasten-interferon und dessen herstellung.
US4966843A (en) * 1982-11-01 1990-10-30 Cetus Corporation Expression of interferon genes in Chinese hamster ovary cells
IT1206302B (it) 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
US5338835A (en) * 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
JP3045539B2 (ja) * 1989-02-21 2000-05-29 ワシントン ユニバーシティ 改変型生殖ホルモン
US5665868A (en) 1990-09-14 1997-09-09 Vittal Mallya Scientific Research Foundation Chromatographic agent and its use for the separation or proteins, polypeptides of metals
US5508261A (en) * 1991-06-18 1996-04-16 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
SE9201073D0 (sv) * 1992-04-03 1992-04-03 Kabi Pharmacia Ab Protein formulation
EP0666914B1 (en) 1992-10-23 2003-12-10 Genetics Institute, LLC Novel p-selectin ligand protein
US6183987B1 (en) 1995-02-17 2001-02-06 Stichting Institut Voor Dierhouderij En Diergezonheld Production of biologically active recombinant bovine follicle stimulation hormone (rec bFSH) in the baculovirus expression system
AUPN801296A0 (en) 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
JP2000517188A (ja) 1996-08-30 2000-12-26 ライフ テクノロジーズ，インコーポレイテッド 無血清哺乳動物細胞培養培地およびその使用
US6162905A (en) * 1996-11-07 2000-12-19 Ibsa Institut Biochimique S.A. FSH and LH separation and purification process
IT1287138B1 (it) * 1996-11-07 1998-08-04 Ibsa Inst Biochimique Sa Procedimento per la separazione e purificazione di fsh e lh
HU222666B1 (hu) * 1996-11-15 2003-09-29 Genentech, Inc. Eljárás neuorotrofinok tisztítására
US5883073A (en) * 1997-04-03 1999-03-16 Washington University Single-chain double-alpha peptide
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JP2002541213A (ja) * 1999-04-13 2002-12-03 インヘール セラピューティック システムズ， インコーポレイテッド 不妊症の処置のための乾燥粉末処方物の肺投与
JP4574865B2 (ja) * 1999-04-16 2010-11-04 インスチチュート マッソーネ エス．エイ． 高度に精製されたゴナドトロピン組成物およびそれらの製造方法
US7431921B2 (en) * 2000-04-14 2008-10-07 Maxygen Aps Interferon beta-like molecules
WO2001058493A1 (en) 2000-02-11 2001-08-16 Maxygen Aps Conjugates of follicle stimulating hormones
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NZ538217A (en) 2002-07-17 2007-04-27 Biogen Idec Inc Beta interferon when used to treat proteinuria, glomerular cell proliferation and inflammation
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UA88879C2 (en) 2003-09-02 2009-12-10 Эплайд Рисерч Системз Эрс Холдинг Н.В. Fsh glycosylation mutant
UA90664C2 (ru) * 2003-12-22 2010-05-25 Ейрес Трейдінг С.А. Способ очистки fsh
US7598356B2 (en) 2004-07-08 2009-10-06 Board of Regents of the University of Nebraska by and on behalf of the University of Nebraska Medical Center Method for purifying a protein of the cystine-knot superfamily
US7294484B2 (en) * 2004-08-27 2007-11-13 Wyeth Research Ireland Limited Production of polypeptides
EP1809663B1 (en) * 2004-11-09 2008-09-17 Ares Trading S.A. Method for purifying fsh
ME01043B (me) * 2004-11-09 2005-11-08 Ares Trading Sa Metode za prećišćavanje fsh-a
RS57549B1 (sr) * 2005-08-26 2018-10-31 Ares Trading Sa Proces za pripremu glikoziliranog interferona beta
ZA200805194B (en) * 2006-01-17 2009-10-28 Serono Lab Novel FSH glycosylation variant D3N

Also Published As

Publication number Publication date
WO2007065918A3 (en) 2007-08-16
WO2007065918A2 (en) 2007-06-14
US8604175B2 (en) 2013-12-10
CA2625978A1 (en) 2007-06-14
JP2009518361A (ja) 2009-05-07
EP1960419A2 (en) 2008-08-27
IL191619A0 (en) 2008-12-29
JP5199112B2 (ja) 2013-05-15
US20090209454A1 (en) 2009-08-20
EP1960419B1 (en) 2016-03-16
AU2006323925B2 (en) 2012-08-02
AU2006323925A1 (en) 2007-06-14

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