AR052541A1 - Vacunas de glicoconjugados que contiene peptidoglicina - Google Patents

Vacunas de glicoconjugados que contiene peptidoglicina

Info

Publication number
AR052541A1
AR052541A1 ARP050105201A ARP050105201A AR052541A1 AR 052541 A1 AR052541 A1 AR 052541A1 AR P050105201 A ARP050105201 A AR P050105201A AR P050105201 A ARP050105201 A AR P050105201A AR 052541 A1 AR052541 A1 AR 052541A1
Authority
AR
Argentina
Prior art keywords
capsular polysaccharide
vaccine
peptidoglycin
glicoconjugated
vaccines containing
Prior art date
Application number
ARP050105201A
Other languages
English (en)
Original Assignee
Nabi Biopharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nabi Biopharmaceuticals filed Critical Nabi Biopharmaceuticals
Publication of AR052541A1 publication Critical patent/AR052541A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/5555—Muramyl dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen

Abstract

Vacunas para tratar infecciones bacterianas, que comprenden un inmunogeno glicoconjugado que consiste en al menos un polisacárido capsular conjugado con una proteína portadora, de modo tal que el polisacárido capsular contiene una cantidad de péptidoglicano eficaz para mejorar las propiedades de la vacuna. Reivindicacion 2: La vacuna de la reivindicacion 1, donde el inmunogeno glicoconjugado comprende un polisacárido capsular expresado por Staphylococcus. Reivindicacion 5: La vacuna de la reivindicacion 1, donde la proteína portadora se selecciona del grupo que consiste en la exotoxina A de Pseudomonas, el toxoide del tétanos y la difteria, la alfa hemolisina, y la leucocidina de Panton-Valentine.
ARP050105201A 2004-12-14 2005-12-12 Vacunas de glicoconjugados que contiene peptidoglicina AR052541A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/010,563 US20060134141A1 (en) 2004-12-14 2004-12-14 Glycoconjugate vaccines containing peptidoglycan

Publications (1)

Publication Number Publication Date
AR052541A1 true AR052541A1 (es) 2007-03-21

Family

ID=36588365

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050105201A AR052541A1 (es) 2004-12-14 2005-12-12 Vacunas de glicoconjugados que contiene peptidoglicina

Country Status (12)

Country Link
US (1) US20060134141A1 (es)
EP (1) EP1846025A2 (es)
JP (1) JP2008523142A (es)
KR (1) KR20070090011A (es)
CN (1) CN101132810A (es)
AR (1) AR052541A1 (es)
AU (1) AU2005316864B2 (es)
CA (1) CA2591442A1 (es)
MX (1) MX2007007090A (es)
NZ (1) NZ556533A (es)
TW (1) TW200633719A (es)
WO (1) WO2006065553A2 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020092987A1 (en) * 1998-09-05 2002-07-18 Taehee Cho Photo detect device using quantum dots and materialization method thereof
US10919956B2 (en) 2002-11-12 2021-02-16 The Brigham And Women's Hospital, Inc. Polysaccharide vaccine for staphylococcal infections
WO2004050846A2 (en) * 2002-12-02 2004-06-17 Biosynexus Incorporated Wall teichoic acid as a target for anti-staphylococcal therapies and vaccines
GB0314372D0 (en) * 2003-06-20 2003-07-23 Dana Corp Bearings
EP1850867A1 (en) * 2005-01-10 2007-11-07 Nabi Biopharmaceuticals Method of treating staphylococcus aureus infection
US20060228368A1 (en) * 2005-04-07 2006-10-12 Nabi Biopharmaceuticals Method of protecting against staphylococcal infection
AU2006257774B2 (en) * 2005-06-13 2012-03-01 Glaxosmithkline Biologicals Sa Use of Panton-Valentine Leukocidin for treating and preventing Staphylococcus infections
JP2009531387A (ja) * 2006-03-30 2009-09-03 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 免疫原性組成物
US20090053235A1 (en) * 2006-06-12 2009-02-26 Nabi Biopharmaceuticals Use of alpha-toxin for treating and preventing staphylococcus infections
WO2009029831A1 (en) * 2007-08-31 2009-03-05 University Of Chicago Methods and compositions related to immunizing against staphylococcal lung diseases and conditions
US9181329B2 (en) 2007-08-31 2015-11-10 The University Of Chicago Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions
KR20110031393A (ko) 2008-07-21 2011-03-25 더 브리검 앤드 우먼즈 하스피털, 인크. 합성 베타-1,6 글루코사민 올리고당에 관한 방법 및 조성물
WO2010014304A1 (en) * 2008-07-29 2010-02-04 University Of Chicago Compositions and methods related to staphylococcal bacterium proteins
HUE057713T2 (hu) 2009-04-03 2022-05-28 Univ Chicago A protein A (SPA) variánsaival kapcsolatos készítmények és módszerek
SG10201406432RA (en) * 2009-06-22 2014-11-27 Wyeth Llc Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions
BRPI1015567A2 (pt) 2009-06-22 2021-08-31 Wyeth Llc Composições imunogênicas de antígenos de staphylococcus aureus
AU2010352695B2 (en) 2009-09-30 2014-08-21 Glaxosmithkline Biologicals S.A. Conjugation of Staphylococcus aureus type 5 and type 8 capsular polysaccharides
EP3199177A1 (en) 2009-10-30 2017-08-02 GlaxoSmithKline Biologicals S.A. Purification of staphylococcus aureus type 5 and type 8 capsular saccharides
WO2012003474A2 (en) 2010-07-02 2012-01-05 The University Of Chicago Compositions and methods related to protein a (spa) variants
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
WO2017064190A1 (en) 2015-10-13 2017-04-20 Sanofi Pasteur Immunogenic compositions against s. aureus
AR109621A1 (es) * 2016-10-24 2018-12-26 Janssen Pharmaceuticals Inc Formulaciones de vacunas contra glucoconjugados de expec
JP2021507959A (ja) * 2017-12-19 2021-02-25 ザ・ガバナーズ・オブ・ザ・ユニバーシティー・オブ・アルバータ ウェルシュ菌（Ｃｌｏｓｔｒｉｄｉｕｍ ｐｅｒｆｒｉｎｇｅｎｓ）表面グリカンおよびその使用
WO2023133143A1 (en) * 2022-01-05 2023-07-13 Bluewillow Biologics, Inc. Intranasal polysaccharide conjugate nanoemulsion vaccines and methods of using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2321896A1 (fr) * 1975-08-29 1977-03-25 Anvar Agents adjuvants immunologiques actifs en solution aqueuse
ES2198405T3 (es) * 1991-11-22 2004-02-01 Nabi Biopharmaceuticals Antigenos de superficie de tipo i asociados a staphylococcus epidermis.
US5770208A (en) * 1996-09-11 1998-06-23 Nabi Staphylococcus aureus B-linked hexosamine antigen
JPH11255664A (ja) * 1998-03-10 1999-09-21 Ajinomoto Co Inc 経口投与用免疫増強剤
DE69940371D1 (de) * 1998-09-14 2009-03-19 Nabi Biopharmaceuticals Rockvi Beta-glucan enthaltende zusammenstellungen und spezifische immunoglobuline
US6936258B1 (en) * 1999-03-19 2005-08-30 Nabi Biopharmaceuticals Staphylococcus antigen and vaccine
US20030113350A1 (en) * 2001-09-19 2003-06-19 Fattom Ali I. Glycoconjugate vaccines for use in immune-compromised populations

Also Published As

Publication number Publication date
CN101132810A (zh) 2008-02-27
US20060134141A1 (en) 2006-06-22
WO2006065553A2 (en) 2006-06-22
MX2007007090A (es) 2008-02-21
NZ556533A (en) 2009-05-31
AU2005316864A1 (en) 2006-06-22
AU2005316864B2 (en) 2010-10-28
CA2591442A1 (en) 2006-06-22
EP1846025A2 (en) 2007-10-24
WO2006065553A3 (en) 2006-10-05
KR20070090011A (ko) 2007-09-04
JP2008523142A (ja) 2008-07-03
TW200633719A (en) 2006-10-01

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