AR052392A1 - Mutantes de la proteina n del virus del sindrome reproductor y respiratorio de los porcinos - Google Patents

Mutantes de la proteina n del virus del sindrome reproductor y respiratorio de los porcinos

Info

Publication number
AR052392A1
AR052392A1 ARP060100696A AR052392A1 AR 052392 A1 AR052392 A1 AR 052392A1 AR P060100696 A ARP060100696 A AR P060100696A AR 052392 A1 AR052392 A1 AR 052392A1
Authority
AR
Argentina
Prior art keywords
porcines
reproductive
mutants
respiratory
protein
Prior art date
Application number
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR052392A1 publication Critical patent/AR052392A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10061—Methods of inactivation or attenuation
    • C12N2770/10062—Methods of inactivation or attenuation by genetic engineering

Abstract

La presente proporciona un virus PRRS modificado genéticamente y polinucleotidos que lo codifican. Se proporcionan también vacunas que comprenden el virus modificado genéticamente y los polinucleotidos.
ARP060100696 2005-02-25 2006-02-24 Mutantes de la proteina n del virus del sindrome reproductor y respiratorio de los porcinos AR052392A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65652305P 2005-02-25 2005-02-25
US73066305P 2005-10-27 2005-10-27

Publications (1)

Publication Number Publication Date
AR052392A1 true AR052392A1 (es) 2007-03-14

Family

ID=36218763

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060100696 AR052392A1 (es) 2005-02-25 2006-02-24 Mutantes de la proteina n del virus del sindrome reproductor y respiratorio de los porcinos

Country Status (15)

Country Link
US (3) US7544362B1 (es)
EP (1) EP1856141A1 (es)
JP (1) JP4320357B2 (es)
KR (2) KR100996105B1 (es)
CN (1) CN101128478B (es)
AR (1) AR052392A1 (es)
AU (1) AU2006253891B2 (es)
BR (1) BRPI0606189A2 (es)
CA (1) CA2599322C (es)
MX (1) MX2007009060A (es)
NO (1) NO20074885L (es)
NZ (1) NZ561848A (es)
RU (1) RU2381035C2 (es)
TW (1) TWI366602B (es)
WO (1) WO2006129139A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ561848A (en) * 2005-02-25 2010-02-26 Pfizer Prod Inc N protein mutants of porcine reproductive and respiratory syndrome virus
WO2010044889A2 (en) * 2008-10-16 2010-04-22 Pfizer Inc. Torque teno virus (ttv) isolates and compositions
US8846388B2 (en) 2009-10-16 2014-09-30 Zoetis Llc Infectious clones of torque teno virus
UA108902C2 (uk) * 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
BR112013030321A2 (pt) 2011-05-27 2017-07-11 Sinovet Beijing Biotechnology Co Ltd composição de vacina, método para preparar a composição de vacina, uso da composição de vacina, método para imunizar um porco, cepa de vacina contra csfv e uso de uma célula no cultivo de uma cepa de vacina contra csfv.
WO2012168818A1 (en) 2011-06-08 2012-12-13 Ah Usa 42 Llc Infectious clones of torque teno virus
US9579377B2 (en) * 2011-06-14 2017-02-28 Globeimmune, Inc. Yeast-based compositions and methods for the treatment or prevention of hepatitis delta virus infection
CN109876139A (zh) * 2012-04-24 2019-06-14 俄亥俄州国家创新基金会 用于治疗和预防猪繁殖与呼吸综合征的组合物和方法
JP6386999B2 (ja) * 2012-05-17 2018-09-05 ゾエティス・エルエルシー ブタ生殖および呼吸症候群（ｐｒｒｓ）ウイルスに対する離乳前の効果的なワクチン接種
KR102276341B1 (ko) * 2020-01-29 2021-07-12 주식회사 바이오포아 유럽형 돼지 생식기 호흡기 증후군 바이러스의 제조 방법 및 이의 용도
KR102402645B1 (ko) * 2020-01-29 2022-05-26 주식회사 바이오포아 유럽형 돼지 생식기 호흡기 증후군 바이러스의 변이주 및 이를 포함하는 백신 조성물
EP4098741A4 (en) * 2020-01-29 2024-04-03 Biopoa Inc MUTANT STRAIN OF EUROPEAN SWINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS, AND VACCINE USING SAME
CN114315984B (zh) * 2021-12-29 2023-02-03 中国农业科学院兰州兽医研究所 一种用于制备prrsv基因ii型表位缺失疫苗毒株的n蛋白表位突变标记及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
CA2290220C (en) * 1998-12-22 2013-11-19 Pfizer Products Inc. An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof
EP1157121B1 (en) * 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Prrsv replicon
WO2002095040A1 (en) * 2001-05-21 2002-11-28 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Delections in arterivirus replicons
MXPA02007198A (es) * 2000-01-26 2002-12-09 Boehringer Ingelheim Vetmed Atenuacion recombinante de prrsv.
WO2002072802A2 (en) * 2001-03-09 2002-09-19 Boehringer Ingelheim Vetmedica Gmbh Live attenuated strains of prrs virus
NZ561848A (en) * 2005-02-25 2010-02-26 Pfizer Prod Inc N protein mutants of porcine reproductive and respiratory syndrome virus

Also Published As

Publication number Publication date
RU2381035C2 (ru) 2010-02-10
AU2006253891B2 (en) 2011-12-01
MX2007009060A (es) 2007-09-11
NO20074885L (no) 2007-11-22
KR20100090311A (ko) 2010-08-13
AU2006253891A1 (en) 2006-12-07
BRPI0606189A2 (pt) 2009-06-09
TW200641126A (en) 2006-12-01
US7544362B1 (en) 2009-06-09
US20090130143A1 (en) 2009-05-21
JP4320357B2 (ja) 2009-08-26
JP2008531006A (ja) 2008-08-14
EP1856141A1 (en) 2007-11-21
CA2599322A1 (en) 2006-12-07
US20090226486A1 (en) 2009-09-10
US8128937B2 (en) 2012-03-06
KR100996105B1 (ko) 2010-11-22
NZ561848A (en) 2010-02-26
RU2007131536A (ru) 2009-03-27
WO2006129139A1 (en) 2006-12-07
CN101128478A (zh) 2008-02-20
CN101128478B (zh) 2013-08-14
TWI366602B (en) 2012-06-21
CA2599322C (en) 2013-09-03
KR20070095453A (ko) 2007-09-28
US20100136051A1 (en) 2010-06-03

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