AR050335A1 - Prodrogas de estradiol, composicion farmaceutica en base al compuesto y procedimiento de preparacion de este - Google Patents
Prodrogas de estradiol, composicion farmaceutica en base al compuesto y procedimiento de preparacion de esteInfo
- Publication number
- AR050335A1 AR050335A1 ARP050102083A ARP050102083A AR050335A1 AR 050335 A1 AR050335 A1 AR 050335A1 AR P050102083 A ARP050102083 A AR P050102083A AR P050102083 A ARP050102083 A AR P050102083A AR 050335 A1 AR050335 A1 AR 050335A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- alkyl
- atom
- cycloalkyl
- halogen atom
- Prior art date
Links
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 title abstract 3
- 229960005309 estradiol Drugs 0.000 title abstract 3
- 229930182833 estradiol Natural products 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
- 125000005843 halogen group Chemical group 0.000 abstract 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 3
- 101100240526 Caenorhabditis elegans nhr-20 gene Proteins 0.000 abstract 3
- 229910006074 SO2NH2 Inorganic materials 0.000 abstract 3
- 125000005275 alkylenearyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 125000002560 nitrile group Chemical group 0.000 abstract 3
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 3
- 125000004469 siloxy group Chemical group [SiH3]O* 0.000 abstract 3
- 125000004429 atom Chemical group 0.000 abstract 2
- 125000002993 cycloalkylene group Chemical group 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940011871 estrogen Drugs 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004025966A DE102004025966A1 (de) | 2004-05-21 | 2004-05-21 | Estradiol-Prodrugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR050335A1 true AR050335A1 (es) | 2006-10-18 |
Family
ID=34969196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050102083A AR050335A1 (es) | 2004-05-21 | 2005-05-20 | Prodrogas de estradiol, composicion farmaceutica en base al compuesto y procedimiento de preparacion de este |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1747230A1 (https=) |
| JP (1) | JP2007538025A (https=) |
| AR (1) | AR050335A1 (https=) |
| DE (1) | DE102004025966A1 (https=) |
| GT (1) | GT200500121A (https=) |
| PA (1) | PA8633701A1 (https=) |
| PE (1) | PE20060359A1 (https=) |
| SV (1) | SV2006002121A (https=) |
| TW (1) | TW200613315A (https=) |
| UY (1) | UY28909A1 (https=) |
| WO (1) | WO2005113574A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10027887A1 (de) | 2000-05-31 | 2001-12-13 | Jenapharm Gmbh | Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
| DE102004025985A1 (de) * | 2004-05-21 | 2005-12-15 | Schering Ag | Estriol- und Estetrol-Prodrugs |
| US7534780B2 (en) | 2004-05-21 | 2009-05-19 | Bayer Schering Pharma Aktiengesellschaft | Estradiol prodrugs |
| DE102005057224A1 (de) * | 2005-11-29 | 2007-05-31 | Bayer Schering Pharma Ag | Prodrugs ERß-selektiver Substanzen, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
| DE102005057225A1 (de) * | 2005-11-29 | 2007-05-31 | Bayer Schering Pharma Ag | Prodrugs ERß-selektiver Substanzen, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
| DE102005057408A1 (de) * | 2005-11-30 | 2007-05-31 | Bayer Schering Pharma Ag | Sulfamoylsulfonat-Prodrugs |
| PE20160655A1 (es) * | 2013-07-11 | 2016-07-08 | Evestra Inc | Profarmacos de formacion de compuestos |
| CN115368427B (zh) * | 2022-08-17 | 2024-02-13 | 南宁师范大学 | 雌二醇硒氰酸酯类化合物及其制备方法与应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1238739A (fr) * | 1958-08-04 | 1960-08-19 | Chimiotherapie Lab Franc | Procédé de préparation de dérivés hydrosolubles de testostérone |
| FR8290M (https=) * | 1968-12-31 | 1970-11-09 | Rech Chimiques Et Ind Mar Lab | |
| US5001234A (en) * | 1987-04-16 | 1991-03-19 | The Upjohn Company | Cyclic hydrocarbons with an aminoalkyl sidechain |
| US5571933A (en) * | 1994-11-17 | 1996-11-05 | Duquesne University Of The Holy Ghost | Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use |
| DE19712488A1 (de) * | 1997-03-25 | 1998-10-01 | Knoell Hans Forschung Ev | Steroidsulfamate, Verfahren zu ihrer Herstellung und Anwendung derselben |
| US6953785B2 (en) * | 2000-04-24 | 2005-10-11 | Kyowa Hakko Kogyo Co., Ltd. | Estra-1,3,5(10)-triene derivatives |
| DE10027887A1 (de) * | 2000-05-31 | 2001-12-13 | Jenapharm Gmbh | Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
| GB0015876D0 (en) * | 2000-06-28 | 2000-08-23 | Novartis Ag | Organic compounds |
| GB0316290D0 (en) * | 2003-07-11 | 2003-08-13 | Glaxo Group Ltd | Novel compounds |
| TWI331154B (en) * | 2003-11-12 | 2010-10-01 | Solvay Pharm Gmbh | Novel 17-hydroxysteroid dehydrogenase type i inhibitors |
| DE102004025985A1 (de) * | 2004-05-21 | 2005-12-15 | Schering Ag | Estriol- und Estetrol-Prodrugs |
-
2004
- 2004-05-21 DE DE102004025966A patent/DE102004025966A1/de not_active Withdrawn
-
2005
- 2005-05-10 WO PCT/EP2005/005254 patent/WO2005113574A1/de not_active Ceased
- 2005-05-10 EP EP05747458A patent/EP1747230A1/de not_active Withdrawn
- 2005-05-10 JP JP2007517046A patent/JP2007538025A/ja active Pending
- 2005-05-19 UY UY28909A patent/UY28909A1/es not_active Application Discontinuation
- 2005-05-20 TW TW094116503A patent/TW200613315A/zh unknown
- 2005-05-20 AR ARP050102083A patent/AR050335A1/es unknown
- 2005-05-20 PA PA20058633701A patent/PA8633701A1/es unknown
- 2005-05-20 GT GT200500121A patent/GT200500121A/es unknown
- 2005-05-20 PE PE2005000557A patent/PE20060359A1/es not_active Application Discontinuation
- 2005-05-23 SV SV2005002121A patent/SV2006002121A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PE20060359A1 (es) | 2006-05-25 |
| PA8633701A1 (es) | 2006-07-03 |
| TW200613315A (en) | 2006-05-01 |
| JP2007538025A (ja) | 2007-12-27 |
| DE102004025966A1 (de) | 2005-12-15 |
| GT200500121A (es) | 2006-01-30 |
| WO2005113574A1 (de) | 2005-12-01 |
| UY28909A1 (es) | 2005-12-30 |
| EP1747230A1 (de) | 2007-01-31 |
| SV2006002121A (es) | 2006-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |