TW200613315A - Estradiol prodrugs - Google Patents
Estradiol prodrugsInfo
- Publication number
- TW200613315A TW200613315A TW094116503A TW94116503A TW200613315A TW 200613315 A TW200613315 A TW 200613315A TW 094116503 A TW094116503 A TW 094116503A TW 94116503 A TW94116503 A TW 94116503A TW 200613315 A TW200613315 A TW 200613315A
- Authority
- TW
- Taiwan
- Prior art keywords
- estradiol
- prodrugs
- production
- estradiol prodrugs
- steroid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention relates to estradiol prodrugs of general formula (I), in which group Z is bonded to the steroid, process for their production, pharmaceutical compositions that contain these compounds, as well as their use for the production of pharmaceutical agents with estrogenic action.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004025966A DE102004025966A1 (en) | 2004-05-21 | 2004-05-21 | Estradiol prodrugs |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200613315A true TW200613315A (en) | 2006-05-01 |
Family
ID=34969196
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW094116503A TW200613315A (en) | 2004-05-21 | 2005-05-20 | Estradiol prodrugs |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1747230A1 (en) |
JP (1) | JP2007538025A (en) |
AR (1) | AR050335A1 (en) |
DE (1) | DE102004025966A1 (en) |
GT (1) | GT200500121A (en) |
PA (1) | PA8633701A1 (en) |
PE (1) | PE20060359A1 (en) |
SV (1) | SV2006002121A (en) |
TW (1) | TW200613315A (en) |
UY (1) | UY28909A1 (en) |
WO (1) | WO2005113574A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115368427A (en) * | 2022-08-17 | 2022-11-22 | 南宁师范大学 | Estradiol selenocyanate compound and preparation method and application thereof |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10027887A1 (en) | 2000-05-31 | 2001-12-13 | Jenapharm Gmbh | Compounds with a sulfonamide group and pharmaceutical compositions containing these compounds |
DE102004025985A1 (en) * | 2004-05-21 | 2005-12-15 | Schering Ag | Estriol and estetrol prodrugs |
US7534780B2 (en) | 2004-05-21 | 2009-05-19 | Bayer Schering Pharma Aktiengesellschaft | Estradiol prodrugs |
DE102005057224A1 (en) * | 2005-11-29 | 2007-05-31 | Bayer Schering Pharma Ag | New 9-alpha substituted estratriene derivatives esterified with a sulfamoylphenyl-substituted acid residue, are prodrugs useful as carboanhydrase inhibitors for treating estrogen deficiency disorders |
DE102005057225A1 (en) * | 2005-11-29 | 2007-05-31 | Bayer Schering Pharma Ag | New 8-beta-substituted estratriene derivatives esterified with a sulfamoylphenyl-substituted acid residue, are prodrugs useful as carboanhydrase inhibitors for treating estrogen deficiency disorders |
DE102005057408A1 (en) * | 2005-11-30 | 2007-05-31 | Bayer Schering Pharma Ag | New sulfamoylsulfonate prodrugs e.g. useful for protecting red blood cells from attack by parasites or for hormone replacement therapy, female fertility control or treating hormone-associated diseases |
CN105636592A (en) * | 2013-07-11 | 2016-06-01 | 伊万斯彻有限公司 | Pro-drug forming compounds |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1238739A (en) * | 1958-08-04 | 1960-08-19 | Chimiotherapie Lab Franc | Process for the preparation of water-soluble testosterone derivatives |
FR8290M (en) * | 1968-12-31 | 1970-11-09 | Rech Chimiques Et Ind Mar Lab | |
US5001234A (en) * | 1987-04-16 | 1991-03-19 | The Upjohn Company | Cyclic hydrocarbons with an aminoalkyl sidechain |
US5571933A (en) * | 1994-11-17 | 1996-11-05 | Duquesne University Of The Holy Ghost | Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use |
DE19712488A1 (en) * | 1997-03-25 | 1998-10-01 | Knoell Hans Forschung Ev | Steroid sulfamates, processes for their preparation and use thereof |
WO2001081364A1 (en) * | 2000-04-24 | 2001-11-01 | Kyowa Hakko Kogyo Co., Ltd. | Estra-1,3,5(10)-triene derivatives |
DE10027887A1 (en) * | 2000-05-31 | 2001-12-13 | Jenapharm Gmbh | Compounds with a sulfonamide group and pharmaceutical compositions containing these compounds |
GB0015876D0 (en) * | 2000-06-28 | 2000-08-23 | Novartis Ag | Organic compounds |
GB0316290D0 (en) * | 2003-07-11 | 2003-08-13 | Glaxo Group Ltd | Novel compounds |
TWI331154B (en) * | 2003-11-12 | 2010-10-01 | Solvay Pharm Gmbh | Novel 17-hydroxysteroid dehydrogenase type i inhibitors |
DE102004025985A1 (en) * | 2004-05-21 | 2005-12-15 | Schering Ag | Estriol and estetrol prodrugs |
-
2004
- 2004-05-21 DE DE102004025966A patent/DE102004025966A1/en not_active Withdrawn
-
2005
- 2005-05-10 JP JP2007517046A patent/JP2007538025A/en active Pending
- 2005-05-10 EP EP05747458A patent/EP1747230A1/en not_active Withdrawn
- 2005-05-10 WO PCT/EP2005/005254 patent/WO2005113574A1/en active Application Filing
- 2005-05-19 UY UY28909A patent/UY28909A1/en not_active Application Discontinuation
- 2005-05-20 PE PE2005000557A patent/PE20060359A1/en not_active Application Discontinuation
- 2005-05-20 TW TW094116503A patent/TW200613315A/en unknown
- 2005-05-20 GT GT200500121A patent/GT200500121A/en unknown
- 2005-05-20 AR ARP050102083A patent/AR050335A1/en unknown
- 2005-05-20 PA PA20058633701A patent/PA8633701A1/en unknown
- 2005-05-23 SV SV2005002121A patent/SV2006002121A/en not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115368427A (en) * | 2022-08-17 | 2022-11-22 | 南宁师范大学 | Estradiol selenocyanate compound and preparation method and application thereof |
CN115368427B (en) * | 2022-08-17 | 2024-02-13 | 南宁师范大学 | Estradiol selenocyanate compound and preparation method and application thereof |
Also Published As
Publication number | Publication date |
---|---|
WO2005113574A1 (en) | 2005-12-01 |
SV2006002121A (en) | 2006-02-15 |
EP1747230A1 (en) | 2007-01-31 |
JP2007538025A (en) | 2007-12-27 |
DE102004025966A1 (en) | 2005-12-15 |
PA8633701A1 (en) | 2006-07-03 |
PE20060359A1 (en) | 2006-05-25 |
GT200500121A (en) | 2006-01-30 |
UY28909A1 (en) | 2005-12-30 |
AR050335A1 (en) | 2006-10-18 |
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