AR047689A1 - Procedimiento para la preparacion de eteres arilicos - Google Patents

Procedimiento para la preparacion de eteres arilicos

Info

Publication number
AR047689A1
AR047689A1 ARP050100593A ARP050100593A AR047689A1 AR 047689 A1 AR047689 A1 AR 047689A1 AR P050100593 A ARP050100593 A AR P050100593A AR P050100593 A ARP050100593 A AR P050100593A AR 047689 A1 AR047689 A1 AR 047689A1
Authority
AR
Argentina
Prior art keywords
formula
compound
procedure
arilic
eters
Prior art date
Application number
ARP050100593A
Other languages
English (en)
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of AR047689A1 publication Critical patent/AR047689A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/02—Preparation of ethers from oxiranes
    • C07C41/03—Preparation of ethers from oxiranes by reaction of oxirane rings with hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La presente comprende un procedimiento enantioselectivo de preparacion de un compuesto de formula (4) en la que n, m, R y R1 son como se definieron en la memoria descriptiva, el cual comprende: (a) epoxidacion asimétrica de un compuesto de formula (1) en la que R1 y m son como se definieron anteriormente, con un agente de oxidacion en presencia de un compuesto opticamente activo, para dar un compuesto de formula (2) en la que R1 y m son como se definieron anteriormente, seguido de (b) reaccion del compuesto de formula (2) con un compuesto de formula (3) en la que R y n son como se definieron anteriormente, en presencia de una base; en donde el procedimiento se lleva a cabo sin aislamiento del compuesto de formula (2). También se describe el uso de los compuestos de formula (4) en un procedimiento de preparacion de compuestos de formula (5) e intermediarios utiles en el procedimiento.
ARP050100593A 2004-02-20 2005-02-18 Procedimiento para la preparacion de eteres arilicos AR047689A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54649504P 2004-02-20 2004-02-20

Publications (1)

Publication Number Publication Date
AR047689A1 true AR047689A1 (es) 2006-02-01

Family

ID=34910781

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050100593A AR047689A1 (es) 2004-02-20 2005-02-18 Procedimiento para la preparacion de eteres arilicos

Country Status (15)

Country Link
US (2) US20050187399A1 (es)
EP (1) EP1730094A1 (es)
JP (1) JP2007523153A (es)
KR (1) KR100796913B1 (es)
CN (1) CN1922124A (es)
AR (1) AR047689A1 (es)
AU (1) AU2005217217B2 (es)
BR (1) BRPI0507917A (es)
CA (1) CA2556063A1 (es)
IL (1) IL177212A0 (es)
NO (1) NO20063537L (es)
RU (1) RU2330012C2 (es)
TW (2) TW200922916A (es)
WO (1) WO2005082824A1 (es)
ZA (1) ZA200606355B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104086431A (zh) * 2014-07-21 2014-10-08 天津药物研究院药业有限责任公司 一种甲磺酸瑞波西汀中间体的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL56369A (en) * 1978-01-20 1984-05-31 Erba Farmitalia Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them
IL63433A (en) * 1980-08-06 1986-04-29 Univ Leland Stanford Junior Method of asymmetrical epoxidation
GB8419683D0 (en) * 1984-08-02 1984-09-05 Erba Farmitalia 3-substituted derivatives of 1-amino-2-hydroxy-propane
GB2167407B (en) * 1984-11-22 1988-05-11 Erba Farmitalia Enantiomers of phenoxy derivatives of benzyl morpholine and salts thereof
US4900847A (en) * 1985-04-04 1990-02-13 Massachusetts Institute Of Technology Catalytic asymmetric epoxidation
IL78187A (en) * 1985-04-04 1991-05-12 Massachusetts Inst Technology Catalytic asymmetric epoxidation
ES2214060T3 (es) * 1998-12-29 2004-09-01 PHARMACIA & UPJOHN COMPANY Procedimiento para la preparacion de arileteres.

Also Published As

Publication number Publication date
IL177212A0 (en) 2006-12-10
ZA200606355B (en) 2008-01-30
KR100796913B1 (ko) 2008-01-22
EP1730094A1 (en) 2006-12-13
BRPI0507917A (pt) 2007-07-10
RU2330012C2 (ru) 2008-07-27
AU2005217217A1 (en) 2005-09-09
US20050187399A1 (en) 2005-08-25
JP2007523153A (ja) 2007-08-16
TW200609208A (en) 2006-03-16
TW200922916A (en) 2009-06-01
NO20063537L (no) 2006-09-01
RU2006129937A (ru) 2008-02-27
CA2556063A1 (en) 2005-09-09
US20090198080A1 (en) 2009-08-06
WO2005082824A1 (en) 2005-09-09
KR20060130179A (ko) 2006-12-18
CN1922124A (zh) 2007-02-28
AU2005217217B2 (en) 2008-03-06

Similar Documents

Publication Publication Date Title
AR047739A1 (es) Polimorfos cristalinos de un ligando receptor de cxc-quimiocina
NI201000054A (es) Compuestos químicos.
ECSP11010889A (es) INHIBIDORES DE cMET
AR069493A1 (es) Mejora del proceso usando tmeda
SV2011003831A (es) Compuestos organicos
CR11827A (es) Activadores de glucoquinasa
GT200200066A (es) Empleo de etoxilatos de alcoholes grasos como favorecedores de la penetracion
UY30228A1 (es) Compuestos quimicos
GT200600430A (es) Compuestos de carboxiamina y metodos de uso de los mismos
ECSP077290A (es) Derivados de isoxazolina y su uso como herbicidas
ES2308299T3 (es) Tiadiazoles como ligandos de receptores de cxc-y cc-quimioquinas.
AR054735A1 (es) Proceso de obtencion de un derivado de piperazina
CY1110688T1 (el) Διεργασια για την παρασκευη καρβεδιλολης και εναντιομερων αυτης
AR049668A1 (es) Proceso quimico para preparar esteres de 4,4 - difluorometil - 3 - oxo - butanoico por reaccion entre una amida y un ester.
MX2009004991A (es) Derivados de monoacetato de ciclopenteno-diol.
AR051936A1 (es) Proceso para la preparacion de pirazoles
AR047689A1 (es) Procedimiento para la preparacion de eteres arilicos
ATE526835T1 (de) Orale zusammensetzung enthaltend difructoseanhydrid
AR057778A1 (es) Proceso para la produccion de anilinas
AR111318A1 (es) Proceso para preparar 2-exo-(2-metilbenciloxi)-1-metil-4-isopropil-7-oxabiciclo[2.2.1]heptano
ECSP045107A (es) Proceso para la reacción de alcaloides y uso de los productos de reacción en la preparación de medicamentos
AR084099A1 (es) Procedimiento mejorado para la preparacion de 2-trifluorometil-5-(1-substituido)-alquilpiridinas
ES2556470T3 (es) Procedimiento para preparar [3-[(6-cloro-3-piridinil)metil]-2-tiazolidiniliden]cianamida
AR053137A1 (es) Proceso para la preparacion de anilinas
CO6331464A2 (es) Inhibidores de cinasa

Legal Events

Date Code Title Description
FA Abandonment or withdrawal