AR047510A1 - Derivados de sulfonamida como agonistas de receptores adrenergicos ??2 - Google Patents
Derivados de sulfonamida como agonistas de receptores adrenergicos ??2Info
- Publication number
- AR047510A1 AR047510A1 ARP050100206A ARP050100206A AR047510A1 AR 047510 A1 AR047510 A1 AR 047510A1 AR P050100206 A ARP050100206 A AR P050100206A AR P050100206 A ARP050100206 A AR P050100206A AR 047510 A1 AR047510 A1 AR 047510A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- group
- sulfonamide derivatives
- cycloalkyl
- formulas
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/42—Y being a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyridine Compounds (AREA)
Abstract
La presente se refiere a derivados de sulfonamida como antagonistas de receptores adrenérgicos beta 2, procesos para su preparacion, composiciones farmacéuticas que los contienen y usos para trastornos y afecciones inflamatorios, alérgicos y respiratorios. Reivindicacion 1: Un compuesto de formula general (1) en la que el grupo (CH2)n-C(=O)Q1 está en posicion relativa meta o para, R1 y R2 se seleccionan independientemente de H y alquilo C1-4, n es 0, 1 o 2 y Q1 es un grupo que se selecciona entre las formulas (2) o (3) y un grupo *-NR11-Q2-A, en el que p es 1 o 2; Q2 es un alquileno C1-4 R11 es H o alquilo C1-4 y A es piridilo, cicloalquilo C3-10 siendo dicho cicloalquilo, opcionalmente esta puenteado por uno o más átomos de C, tetrahidropiranilo, piperidinilo opcionalmente sustituido con bencilo, tetrahidrotiopiranilo o un grupo de las formulas (4) o (5) en el que R3, R4, R5, R6 y R7 son iguales o diferentes y se seleccionan de H, alquilo C1-4, OR8, SR9, halo, CN, CF3, OCF3, COOR9, SO2NR9R10, CONR9R10, NR9R10, NHCOR10 y fenilo; en los que R8 es alquilo C1-4 y R9 y R10 son iguales o diferentes y se seleccionan de H o alquilo C1-4 y el * representa el punto de union al grupo carbonilo; o, si fuera apropiado, sus sales y/o isomeros, tautomeros, solvatos o variaciones isotopicas farmacéuticamente aceptables.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04290168 | 2004-01-22 | ||
GB0406388A GB0406388D0 (en) | 2004-03-22 | 2004-03-22 | Sulfonamide derivatives for the treatment of diseases |
US60025904P | 2004-08-09 | 2004-08-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR047510A1 true AR047510A1 (es) | 2006-01-25 |
Family
ID=43063961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050100206A AR047510A1 (es) | 2004-01-22 | 2005-01-20 | Derivados de sulfonamida como agonistas de receptores adrenergicos ??2 |
Country Status (41)
Country | Link |
---|---|
US (1) | US7351742B2 (es) |
EP (1) | EP1708992B1 (es) |
JP (1) | JP4036343B2 (es) |
KR (1) | KR100785580B1 (es) |
CN (1) | CN1910144B (es) |
AP (1) | AP2378A (es) |
AR (1) | AR047510A1 (es) |
AT (1) | ATE369333T1 (es) |
AU (1) | AU2005214154B2 (es) |
BR (1) | BRPI0507041A (es) |
CA (1) | CA2553293C (es) |
CO (1) | CO5720993A2 (es) |
CY (1) | CY1106894T1 (es) |
DE (1) | DE602005001929T2 (es) |
DK (1) | DK1708992T3 (es) |
DO (1) | DOP2005000004A (es) |
EA (1) | EA009735B1 (es) |
EC (1) | ECSP066701A (es) |
ES (1) | ES2289691T3 (es) |
GE (1) | GEP20084452B (es) |
HK (1) | HK1096083A1 (es) |
HN (1) | HN2005000030A (es) |
HR (1) | HRP20070452T3 (es) |
IL (1) | IL176629A (es) |
MA (1) | MA28303A1 (es) |
ME (1) | ME00557A (es) |
MY (1) | MY139690A (es) |
NL (1) | NL1028086C2 (es) |
NO (1) | NO20063761L (es) |
NZ (1) | NZ548235A (es) |
OA (1) | OA13361A (es) |
PA (1) | PA8621901A1 (es) |
PE (1) | PE20050765A1 (es) |
PL (1) | PL1708992T3 (es) |
PT (1) | PT1708992E (es) |
RS (1) | RS50538B (es) |
SI (1) | SI1708992T1 (es) |
TW (1) | TWI273099B (es) |
UA (1) | UA82283C2 (es) |
UY (1) | UY28724A1 (es) |
WO (1) | WO2005080324A1 (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GT200500281A (es) | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
CA2614757C (en) * | 2005-07-18 | 2011-11-08 | Pfizer Limited | Process for the preparation of sulfonamide derivatives |
GB0516313D0 (en) | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
BRPI0614290A2 (pt) | 2005-08-08 | 2011-03-22 | Argenta Discovery Ltd | derivados de biciclo [ 2.2.1 ] hept-7-ilamina e seus usos |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
CA2643097C (en) | 2006-03-20 | 2012-03-13 | Pfizer Limited | Amine derivatives |
NZ571429A (en) | 2006-04-21 | 2011-09-30 | Novartis Ag | Purine derivatives for use as adenosine A2A receptor agonists |
WO2008041095A1 (en) * | 2006-10-04 | 2008-04-10 | Pfizer Limited | Sulfonamide derivatives as adrenergic agonists and muscarinic antagonists |
DE102007018151A1 (de) | 2007-04-16 | 2008-10-23 | Günenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
US7713463B1 (en) * | 2007-11-13 | 2010-05-11 | Nuvasive, Inc. | Method of manufacturing embroidered surgical implants |
PL2231642T3 (pl) | 2008-01-11 | 2014-04-30 | Novartis Ag | Pirymidyny jako inhibitory kinazy |
US8263623B2 (en) * | 2008-07-11 | 2012-09-11 | Pfizer Inc. | Triazol derivatives useful for the treatment of diseases |
US8236786B2 (en) | 2008-08-07 | 2012-08-07 | Pulmagen Therapeutics (Inflammation) Limited | Respiratory disease treatment |
CN102272104B (zh) | 2008-12-30 | 2014-07-09 | 帕尔马根治疗(炎症)有限公司 | 用于治疗呼吸疾病的磺酰胺化合物 |
SG175330A1 (en) | 2009-04-23 | 2011-11-28 | Theravance Inc | DIAMIDE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND ß2 ADRENERGIC RECEPTOR AGONIST ACTIVITY |
CA2760284A1 (en) | 2009-05-29 | 2010-12-02 | Pfizer Limited | Novel glucocorticoid receptor agonists |
WO2010150014A1 (en) | 2009-06-24 | 2010-12-29 | Pulmagen Therapeutics (Inflammation) Limited | 5r- 5 -deuterated glitazones for respiratory disease treatment |
JP5801997B2 (ja) | 2009-07-07 | 2015-10-28 | ファイザー・リミテッドPfizer Limited | 薬品の組合せを吸入するための投薬ユニット、投薬ユニットのパック、および吸入器 |
GB0918923D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminothiazole derivatives |
GB0918924D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Azaindole derivatives |
GB0918922D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminopyridine derivatives |
WO2011098746A1 (en) | 2010-02-09 | 2011-08-18 | Pulmagen Therapeutics (Inflammation) Limited | Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone |
GB201002224D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
GB201002243D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
US8637516B2 (en) | 2010-09-09 | 2014-01-28 | Irm Llc | Compounds and compositions as TRK inhibitors |
CA2828219A1 (en) | 2011-02-25 | 2012-08-30 | Irm Llc | Pyrazolo [1,5-a] pyridines as trk inhibitors |
DK2718280T3 (en) | 2011-06-10 | 2016-01-11 | Chiesi Farma Spa | Compositions with muscarinreceptorantagonist- and beta2-adrenoreceptor agonist activity |
WO2014086927A1 (en) | 2012-12-06 | 2014-06-12 | Chiesi Farmaceutici S.P.A. | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
RS60864B1 (sr) | 2012-12-06 | 2020-11-30 | Chiesi Farm Spa | Jedinjenja koja imaju aktivnost antagonista muskarinskog receptora i agonista beta2 adrenergičkog receptora |
EP4171525A1 (en) | 2020-06-26 | 2023-05-03 | Mylan Pharma UK Limited | Formulations including 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4404224A (en) | 1981-12-02 | 1983-09-13 | American Cyanamid Company | Alkanesulfonanilide derivatives and pharmaceutically acceptable acid addition salts thereof for increasing the growth rate and/or improving the lean meat to fat ratio of warm blooded animals |
US4540581A (en) * | 1984-01-31 | 1985-09-10 | Bristol-Myers Company | Topical nonsteroidal anti-inflammatory compositions and uses |
KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
US5776983A (en) | 1993-12-21 | 1998-07-07 | Bristol-Myers Squibb Company | Catecholamine surrogates useful as β3 agonists |
JPH10218861A (ja) | 1997-02-04 | 1998-08-18 | Yamanouchi Pharmaceut Co Ltd | 新規なフェネタノール誘導体又はその塩 |
GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
US6541669B1 (en) | 1998-06-08 | 2003-04-01 | Theravance, Inc. | β2-adrenergic receptor agonists |
US20020143034A1 (en) * | 1998-12-30 | 2002-10-03 | Fujisawa Pharmaceutical Co. Ltd. | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists |
OA11558A (en) | 1999-12-08 | 2004-06-03 | Advanced Medicine Inc | Beta 2-adrenergic receptor agonists. |
AUPQ841300A0 (en) | 2000-06-27 | 2000-07-20 | Fujisawa Pharmaceutical Co., Ltd. | New aminoalcohol derivatives |
US6465501B2 (en) | 2000-07-17 | 2002-10-15 | Wyeth | Azolidines as β3 adrenergic receptor agonists |
US7048994B2 (en) * | 2001-02-23 | 2006-05-23 | Teijin Limited | Laminated polyester film and magnetic recording medium |
US20030229058A1 (en) * | 2001-11-13 | 2003-12-11 | Moran Edmund J. | Aryl aniline beta2 adrenergic receptor agonists |
AU2003239880A1 (en) * | 2002-05-28 | 2003-12-12 | Theravance, Inc. | ALKOXY ARYL Beta2 ADRENERGIC RECEPTOR AGONISTS |
EP1477167A1 (en) * | 2003-05-15 | 2004-11-17 | Pfizer Limited | [(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl] phenyl derivatives as beta2 agonists |
-
2005
- 2005-01-12 CN CN2005800030044A patent/CN1910144B/zh not_active Expired - Fee Related
- 2005-01-12 CA CA2553293A patent/CA2553293C/en not_active Expired - Fee Related
- 2005-01-12 KR KR1020067014814A patent/KR100785580B1/ko not_active IP Right Cessation
- 2005-01-12 JP JP2006550334A patent/JP4036343B2/ja not_active Expired - Fee Related
- 2005-01-12 DE DE602005001929T patent/DE602005001929T2/de active Active
- 2005-01-12 AP AP2006003671A patent/AP2378A/xx active
- 2005-01-12 GE GEAP20059537A patent/GEP20084452B/en unknown
- 2005-01-12 SI SI200530059T patent/SI1708992T1/sl unknown
- 2005-01-12 BR BRPI0507041-4A patent/BRPI0507041A/pt not_active IP Right Cessation
- 2005-01-12 WO PCT/IB2005/000112 patent/WO2005080324A1/en active Application Filing
- 2005-01-12 PT PT05702274T patent/PT1708992E/pt unknown
- 2005-01-12 PL PL05702274T patent/PL1708992T3/pl unknown
- 2005-01-12 OA OA1200600233A patent/OA13361A/en unknown
- 2005-01-12 AT AT05702274T patent/ATE369333T1/de active
- 2005-01-12 RS RSP-2007/0409A patent/RS50538B/sr unknown
- 2005-01-12 DK DK05702274T patent/DK1708992T3/da active
- 2005-01-12 ES ES05702274T patent/ES2289691T3/es active Active
- 2005-01-12 NZ NZ548235A patent/NZ548235A/en not_active IP Right Cessation
- 2005-01-12 EP EP05702274A patent/EP1708992B1/en active Active
- 2005-01-12 AU AU2005214154A patent/AU2005214154B2/en not_active Ceased
- 2005-01-12 EA EA200601141A patent/EA009735B1/ru not_active IP Right Cessation
- 2005-01-12 ME MEP-736/08A patent/ME00557A/xx unknown
- 2005-01-18 TW TWSULFONAMIA patent/TWI273099B/zh not_active IP Right Cessation
- 2005-01-18 MY MYPI20050195A patent/MY139690A/en unknown
- 2005-01-19 US US11/038,416 patent/US7351742B2/en not_active Expired - Fee Related
- 2005-01-20 PE PE2005000078A patent/PE20050765A1/es not_active Application Discontinuation
- 2005-01-20 AR ARP050100206A patent/AR047510A1/es unknown
- 2005-01-20 DO DO2005000004A patent/DOP2005000004A/es unknown
- 2005-01-21 UY UY28724A patent/UY28724A1/es unknown
- 2005-01-21 NL NL1028086A patent/NL1028086C2/nl not_active IP Right Cessation
- 2005-01-21 PA PA20058621901A patent/PA8621901A1/es unknown
- 2005-01-21 HN HN2005000030A patent/HN2005000030A/es unknown
- 2005-12-01 UA UAA200608230A patent/UA82283C2/uk unknown
-
2006
- 2006-06-29 IL IL176629A patent/IL176629A/en not_active IP Right Cessation
- 2006-07-13 EC EC2006006701A patent/ECSP066701A/es unknown
- 2006-07-18 CO CO06070683A patent/CO5720993A2/es not_active Application Discontinuation
- 2006-07-21 MA MA29202A patent/MA28303A1/fr unknown
- 2006-08-22 NO NO20063761A patent/NO20063761L/no not_active Application Discontinuation
-
2007
- 2007-03-30 HK HK07103445.8A patent/HK1096083A1/xx not_active IP Right Cessation
- 2007-09-27 CY CY20071101245T patent/CY1106894T1/el unknown
- 2007-09-27 HR HR20070452T patent/HRP20070452T3/xx unknown
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