AR046775A1 - Procedimiento para preparar derivados de piridina, y compuestos intermediarios utiles en dicho proceso - Google Patents

Procedimiento para preparar derivados de piridina, y compuestos intermediarios utiles en dicho proceso

Info

Publication number
AR046775A1
AR046775A1 ARP040104854A ARP040104854A AR046775A1 AR 046775 A1 AR046775 A1 AR 046775A1 AR P040104854 A ARP040104854 A AR P040104854A AR P040104854 A ARP040104854 A AR P040104854A AR 046775 A1 AR046775 A1 AR 046775A1
Authority
AR
Argentina
Prior art keywords
aryl
branched
alkyl
cyclic
linear
Prior art date
Application number
ARP040104854A
Other languages
English (en)
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34923925&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR046775(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Basf Ag filed Critical Basf Ag
Publication of AR046775A1 publication Critical patent/AR046775A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)

Abstract

Procedimiento para preparar derivados de piridina y compuestos intermediarios útiles para dicho procedimiento. Reivindicación 1: Procedimiento para preparar derivados de piridina sustituida de la formula (1) en donde R1, R2 de modo independiente, igual o diferente, son H; alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 donde cada uno de ellos puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20, amino; F; Cl; Br; I; R3 = CN, NO2, alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 cada uno de los cuales puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20, amino; F; Cl; Br; I; R4 = EnR6m en donde cuando n = m = 1 entonces E = S y R6 = alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 cada uno de los cuales puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20, amino; F, Cl, Br, I; cuando n = 0 y m = 1, entonces R6 = H, alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 cada uno de los cuales puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20, amino; F, Cl, Br, I; E1 = O, N; R5 = H, n = 1 para E1 = O y 2 para E1 = N, caracterizado porque comprende la reacción de un compuesto de carbonilo a-b-insaturado de la formula R3-C(O)-C(R1)=C(R2)-G en donde R1, R2 y R3 tienen el significado definido con anterioridad; G = -NH2 o un grupo saliente con un reactivo de Witting o un reactivo de Horner-Wadsworth-Emmons de formula (2) ó (3) en donde (P)=P(Ar)3, con Ar = arilo C6-20 sustituido o preferentemente insustituido, R' = igual o diferente, de modo independiente, significa alquilo C1-20, ramificado o lineal o cíclico, o arilo C6-20; EnR6m = en donde cuando n = m = 1, entonces E = S y R6 = alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 cada uno de ellos puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I alcoxi C1-20, ariloxi C6-20, amino; F; Cl; Br; I; cuando n = 0 y m = 1, entonces R6 = H, alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 donde cada uno de ellos puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20, amino; F; Cl; Br; I; Y = -CN; -C(O)NH2, -C(O)OR7 con R7 = tal como se definió para R1 con anterioridad, salvo H en presencia de una base y cuando i) Y = -CN o C(O)NH2, G = un grupo saliente y la base es un alcoholato, posterior ciclación con catalizador ácido, con zeolitas o con catalizador básico; ii) Y = -C(O)-OR7, G = un grupo saliente y la base es un alcoholato, posterior ciclación básica en presencia de amoniaco. Reivindicación 5: Compuestos intermediarios de fósforo caracterizados porque tienen la formula (3) en donde R' = igual o diferente, de modo independiente, significa alquilo C1-20, ramificado o lineal o cíclico, o arilo C6-20, EnR6m = en donde cuando n = m = 1, entonces E = S y R6 = alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 en donde cada uno de ellos puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20, amino; F; Cl; Br; I; Y = -CN; -C(O)NH2, -C(O)OR7 con R7 = alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 cada uno de los cuales puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20, amino; F; Cl; Br; I. Reivindicación 6: Compuestos intermediarios caracterizados porque tienen las estructuras seleccionadas del grupo de formulas (4) en donde las variables tienen los siguientes significados: EnR6m = en donde cuando n = m = 1, entonces E = S y R6 = alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 en donde cada uno de ellos puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20, amino; F; Cl; Br; I; cuando n = 0 y m = 1, entonces R6 = H, alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 cada uno de los cuales puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20, amino; F; Cl; Br, I; Y = -CN; -C(O)NH2, - C(O)OR7 con R7 = alquilo C1-20 (ramificado o lineal o cíclico); arilo C6-20 cada uno de los cuales puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20, amino; F; Cl; Br; I, R' = igual o diferente, de modo independiente, significa alquilo C1-20, (ramificado o lineal o cíclico); R3 = CN, NO2, alquilo C1-20 (de cadena ramificada o lineal o cíclico); arilo C6-20 cada uno de los cuales puede estar sustituido con uno o varios de los siguientes grupos: F, Cl, Br, I, alcoxi C1-20, ariloxi C6-20 amino; F; Cl; Br; I; G = -NH2 o un grupo saliente.
ARP040104854A 2003-12-23 2004-12-22 Procedimiento para preparar derivados de piridina, y compuestos intermediarios utiles en dicho proceso AR046775A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53161403P 2003-12-23 2003-12-23
EP03029730 2003-12-23

Publications (1)

Publication Number Publication Date
AR046775A1 true AR046775A1 (es) 2005-12-21

Family

ID=34923925

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040104854A AR046775A1 (es) 2003-12-23 2004-12-22 Procedimiento para preparar derivados de piridina, y compuestos intermediarios utiles en dicho proceso

Country Status (16)

Country Link
US (1) US7687632B2 (es)
EP (1) EP1723156B1 (es)
JP (3) JP5160092B2 (es)
KR (1) KR101164694B1 (es)
CN (1) CN1898255B (es)
AR (1) AR046775A1 (es)
AU (1) AU2004309054B2 (es)
BR (1) BRPI0418047B8 (es)
CA (1) CA2550693C (es)
DK (1) DK1723156T3 (es)
ES (1) ES2528716T3 (es)
IL (1) IL176472A (es)
IN (2) IN2012DN02545A (es)
PL (1) PL1723156T3 (es)
WO (1) WO2005063780A1 (es)
ZA (1) ZA200605471B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7678920B2 (en) * 2004-04-08 2010-03-16 Dow Agrosciences Llc Insecticidal N-substituted sulfoximines
WO2006012320A1 (en) * 2004-06-25 2006-02-02 Dow Agrosciences Llc Process for the preparation of 4-trifluoromethyl-2(1h)-pyridinone
TWI398433B (zh) * 2006-02-10 2013-06-11 Dow Agrosciences Llc 殺蟲性之ｎ-取代（６-鹵烷基吡啶-３-基）烷基磺醯亞胺
TWI381811B (zh) * 2006-06-23 2013-01-11 Dow Agrosciences Llc 用以防治可抵抗一般殺蟲劑之昆蟲的方法
ES2389385T3 (es) * 2006-09-01 2012-10-25 Dow Agrosciences Llc (2-sustituido-1,3-tiazol)alquil sulfoximinas N-sustituidas insecticidas
TWI387585B (zh) * 2006-09-01 2013-03-01 Dow Agrosciences Llc 殺蟲性之ｎ-取代（雜芳基）烷基烴基硫亞胺
TWI395736B (zh) * 2006-11-08 2013-05-11 Dow Agrosciences Llc 作為殺蟲劑之雜芳基（取代的）烷基ｎ-取代的磺醯亞胺（二）
US7709648B2 (en) * 2007-02-09 2010-05-04 Dow Agrosciences Llc Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines
AR066366A1 (es) * 2007-05-01 2009-08-12 Dow Agrosciences Llc Mezclas sinergicas plaguicidas
AU2008279513B2 (en) * 2007-07-20 2013-09-26 Dow Agrosciences Llc Increasing plant vigor
MX2010009748A (es) * 2008-03-03 2010-11-30 Dow Agrosciences Llc Plaguicidas.
CN102875548A (zh) * 2011-07-14 2013-01-16 中国科学院大连化学物理研究所 一类基于肟的通过[2+2+2]环加成合成吡啶衍生物的方法
EP2607343A1 (en) 2011-12-22 2013-06-26 Solvay Sa Process for the manufacture of halogenated precursors of alkenones and of alkenones
JP7282031B2 (ja) * 2016-12-01 2023-05-26 シンジェンタ パーティシペーションズ アーゲー 硫黄含有置換基を有する殺有害生物的に活性な複素環式誘導体
WO2020139740A1 (en) * 2018-12-27 2020-07-02 Dow Agrosciences Llc Preparation of sulfonamide herbicide process intermediates
CN113272277A (zh) * 2018-12-27 2021-08-17 科迪华农业科技有限责任公司 磺酰胺除草剂方法中间体的制备
CN115286568B (zh) * 2022-08-24 2023-12-12 常州沃腾化工科技有限公司 一种2-羟基-4-三氟甲基吡啶的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE611728A (fr) * 1960-07-12 1962-06-19 American Cyanamid Co Perfectionnements aux compositions contenant des antibiotiques à base de tétracycline
US3993656A (en) * 1974-11-19 1976-11-23 Merck & Co., Inc. 1,8-Naphthyridine compounds
JPS5221196A (en) * 1975-08-12 1977-02-17 Fujio Hashimoto Device for removing red tide
JPS53121764A (en) * 1977-03-31 1978-10-24 Yamanouchi Pharmaceut Co Ltd Heterocyclic compounds and process for their preparation
JPS53127490A (en) * 1977-04-13 1978-11-07 Yamanouchi Pharmaceut Co Ltd Novel nitrogen-containing heterocyclic compound
JPS5384990A (en) * 1976-12-29 1978-07-26 Yamanouchi Pharmaceut Co Ltd Novel nitrogen-containing heterocyclic compound and its preparation
JPS55104266A (en) * 1979-02-02 1980-08-09 Yamanouchi Pharmaceut Co Ltd Novel pyridone derivative
JPS6210087A (ja) * 1985-07-03 1987-01-19 Shionogi & Co Ltd ４，７−ジヒドロチエノ〔２，３−ｂ〕ピリジン誘導体，その製造法および循環器系疾患治療剤
JPS6413065A (en) * 1987-07-06 1989-01-17 Mitsubishi Chem Ind Peptide derivative of beta-chloro-l-(z)- dehydroglutamic acid
DK177191D0 (da) * 1991-10-23 1991-10-23 Novo Nordisk As Heterocyclic compounds and their preparation and use
US5391745A (en) * 1992-07-23 1995-02-21 Sloan-Kettering Institute For Cancer Research Methods of preparation of camptothecin analogs
BR9706774B1 (pt) 1996-09-24 2009-01-13 composto de n-(triazolazinil) arilsulfonamida, composiÇço herbicida, mÉtodo de controle de vegetaÇço indesejÁvel e compostos de cloreto de piridina-3-sulfonila e de 2-amino [1,2,4] triazol [1,5-c] pirimidina.
US6417185B1 (en) * 1998-06-19 2002-07-09 Chiron Corporation Inhibitors of glycogen synthase kinase 3
AU2001278491A1 (en) * 2000-07-18 2002-01-30 Basf Aktiengesellschaft 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides
US6399781B1 (en) 2000-10-10 2002-06-04 Boehringer Ingelheim Chemicals, Inc. Process for making 3-amino-2-chloro-4-methylpyridine
WO2006012320A1 (en) * 2004-06-25 2006-02-02 Dow Agrosciences Llc Process for the preparation of 4-trifluoromethyl-2(1h)-pyridinone

Also Published As

Publication number Publication date
BRPI0418047A (pt) 2007-04-17
PL1723156T3 (pl) 2015-07-31
WO2005063780A1 (en) 2005-07-14
JP2013047245A (ja) 2013-03-07
IL176472A (en) 2010-11-30
ZA200605471B (en) 2007-11-28
JP2012214487A (ja) 2012-11-08
BRPI0418047B1 (pt) 2013-12-31
EP1723156B1 (en) 2015-01-21
KR20060128896A (ko) 2006-12-14
AU2004309054A1 (en) 2005-07-14
CN1898255A (zh) 2007-01-17
AU2004309054B2 (en) 2010-07-08
IN2012DN02546A (es) 2015-08-28
EP1723156A1 (en) 2006-11-22
US7687632B2 (en) 2010-03-30
ES2528716T3 (es) 2015-02-12
KR101164694B1 (ko) 2012-07-11
JP2007519625A (ja) 2007-07-19
CA2550693C (en) 2013-07-30
CN1898255B (zh) 2010-06-09
US20070249837A1 (en) 2007-10-25
IL176472A0 (en) 2006-10-05
CA2550693A1 (en) 2005-07-14
BRPI0418047B8 (pt) 2022-06-28
IN2012DN02545A (es) 2015-07-17
DK1723156T3 (en) 2015-04-27
JP5160092B2 (ja) 2013-03-13

Similar Documents

Publication Publication Date Title
AR046775A1 (es) Procedimiento para preparar derivados de piridina, y compuestos intermediarios utiles en dicho proceso
CY1124357T1 (el) Προσδιορισμος ανισορροπιας αλληλουχιας νουκλεϊκων οξεων
CA2613226C (en) Inhibitors of 17beta-hydroxysteroid dehydrogenase type 3
EA200000834A1 (ru) Фунгицидные 7-алкилтриазолопиримидины
AR043508A1 (es) 1-amino 1-h-imidazoquinolinas y su uso como inmunomoduladores
CO5700733A2 (es) Acidos aminocarboxilicos sustituidos
AR065471A1 (es) Proceso para la preparacion de ciertas sulfiliminas sustituidas
HRP20070328T3 (en) SUBSTITUTED 8'-PYRI(MI)DINYL-DIHYDROSPIRO-[CYCLOALKLYMINE]-PYRIMIDO[1,2a]PYRIMIDIN-6-ONE DERIVATIVES
ATE354181T1 (de) Phenyl pyridine-iridium metal-komplexverbindungen für organische elektroluminizierende vorrichtung, verfahren zur herstellung der verbindungen und organische elektroluminizierende vorrichtung die diese verbindungen verwendet
AR061835A1 (es) Derivados tetraciclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen
CO5631434A2 (es) Derivados de piridina-carboxamida y su uso como plaguicidas
PE20050336A1 (es) Compuestos triciclicos como inhibidores de la proteina farnesil transferasa
EA200401482A1 (ru) Ненуклезидные ингибиторы обратной транскриптазы
NZ337766A (en) Process for preparing pesticidal pyrazole derivatives
CO4600635A1 (es) Procedimientos e intermedios para preparar derivados de cromanol sustituidos
EA200100825A1 (ru) Новые 1-арил-4-тиотриазины
CO5540311A2 (es) Derivados de pirimidina utiles como inhibidores de cox-2 selectivos
DE50001567D1 (de) Neue chirale phosphorliganden und ihre verwendung in der herstellung optisch aktiver produkte
EA200600551A1 (ru) Соединения пиперазина, способ их получения и фармацевтические композиции, которые их содержат
DE502005004209D1 (de) Verfahren zur reinigung und isolierung von nukleinsäuren unter verwendung kationischer detergentien
CO5640113A2 (es) Amidas de acido pieprazinil o piepridinilamin-sulfamico como inhibidores de la sulfatasa esteroidal
DE50107981D1 (de) Verfahren zur reinigung von abgasströmen
AR037213A1 (es) Metodos para utilizar compuestos a base de dibenzotiepinas sustituidas y sus derivados como agentes insecticidas, acaricidas y nematicidas
DE50108172D1 (de) Verfahren zur herstellung von spirocyclischen tetronsäurederivaten
EA200300458A1 (ru) Новые соединения аминотриазолона, способ их получения и фармацевтические композиции, содержащие их

Legal Events

Date Code Title Description
FG Grant, registration