AR044985A1 - Metodo y parche de inmunizacion por disposicion de microproyeccion - Google Patents
Metodo y parche de inmunizacion por disposicion de microproyeccionInfo
- Publication number
- AR044985A1 AR044985A1 ARP040102324A ARP040102324A AR044985A1 AR 044985 A1 AR044985 A1 AR 044985A1 AR P040102324 A ARP040102324 A AR P040102324A AR P040102324 A ARP040102324 A AR P040102324A AR 044985 A1 AR044985 A1 AR 044985A1
- Authority
- AR
- Argentina
- Prior art keywords
- microprojection
- amount
- patch
- provision
- members
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Anesthesiology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se describen miembros microproyección (fig.10) que tienen un reservorio que contiene un agente antigénico y métodos de uso de dichos miembros para vacunar mamíferos (por ejemplo seres humanos). Los miembros de microproyección se usan para liberar trnasdérmicamente un agente antigénico (por ejemplo un antígeno de vacuna) con reacciones de la piel sustancialmente reducidas. Esto se logra administrando una cantidad inductora y liberando a continuación una o más cantidades subsiguientes de refuerzo. La cantidad inductora es relativamente mayor que la cantidad de refuerzo. Esta tecnología tiene una amplia aplicabilidad para una amplia variedad de vacunas para mejorar la eficacia y conveniencia de uso.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48493003P | 2003-07-02 | 2003-07-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR044985A1 true AR044985A1 (es) | 2005-10-12 |
Family
ID=33564036
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP040102324A AR044985A1 (es) | 2003-07-02 | 2004-07-01 | Metodo y parche de inmunizacion por disposicion de microproyeccion |
Country Status (13)
Country | Link |
---|---|
US (1) | US20050025778A1 (es) |
EP (1) | EP1643918A1 (es) |
JP (1) | JP2007521092A (es) |
KR (1) | KR20060037320A (es) |
CN (1) | CN1845708A (es) |
AR (1) | AR044985A1 (es) |
AU (1) | AU2004253571A1 (es) |
BR (1) | BRPI0412202A (es) |
CA (1) | CA2530954A1 (es) |
PE (1) | PE20050288A1 (es) |
TW (1) | TW200513280A (es) |
UY (1) | UY28398A1 (es) |
WO (1) | WO2005002453A1 (es) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
US6908453B2 (en) * | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
KR101323980B1 (ko) | 2002-07-19 | 2013-10-30 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 마이크로 니들 장치, 마이크로 니들 장치를 사용하는 방법 및 마이크로 니들 장치를 송출하는 방법 |
US7220422B2 (en) * | 2003-05-20 | 2007-05-22 | Allergan, Inc. | Methods and compositions for treating eye disorders |
ES2437565T3 (es) * | 2003-06-30 | 2014-01-13 | Alza Corporation | Formulaciones para microproyecciones revestidas que contienen contraiones no volátiles |
US8961477B2 (en) * | 2003-08-25 | 2015-02-24 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
AU2004292954A1 (en) * | 2003-11-13 | 2005-06-09 | Alza Corporation | Composition and apparatus for transdermal delivery |
AU2004311977A1 (en) * | 2003-12-29 | 2005-07-21 | 3M Innovative Properties Company | Medical devices and kits including same |
US20070191761A1 (en) * | 2004-02-23 | 2007-08-16 | 3M Innovative Properties Company | Method of molding for microneedle arrays |
WO2005103303A2 (en) * | 2004-04-13 | 2005-11-03 | Alza Corporation | Apparatus and method for transdermal delivery of multiple vaccines |
US8057842B2 (en) | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
KR101224257B1 (ko) * | 2004-11-18 | 2013-01-18 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 마이크로니들 어레이를 코팅하기 위한 마스킹 방법 |
WO2006055802A1 (en) | 2004-11-18 | 2006-05-26 | 3M Innovative Properties Company | Microneedle array applicator and retainer |
KR101246015B1 (ko) | 2004-11-18 | 2013-03-20 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 마이크로니들 어레이를 접촉 코팅하는 방법 |
US8267889B2 (en) | 2004-11-18 | 2012-09-18 | 3M Innovative Properties Company | Low-profile microneedle array applicator |
CA2589733C (en) | 2004-12-07 | 2014-02-11 | 3M Innovative Properties Company | Method of molding a microneedle |
US7691298B2 (en) * | 2005-01-21 | 2010-04-06 | Wisconsin Alumni Research Foundation | Plastic cantilevers for force microscopy |
AU2006213994A1 (en) * | 2005-02-16 | 2006-08-24 | Alza Corporation | Microprojection arrays with improved biocompatibility |
TW200738252A (en) * | 2005-02-16 | 2007-10-16 | Alza Corp | Apparatus and method for transdermal delivery of Epoetin-based agents |
EP1871459B1 (en) | 2005-04-07 | 2019-06-19 | 3M Innovative Properties Company | System for tool feedback sensing |
US8048017B2 (en) | 2005-05-18 | 2011-11-01 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
EP1904158B1 (en) * | 2005-06-24 | 2013-07-24 | 3M Innovative Properties Company | Collapsible patch with microneedle array |
EP1901799B1 (en) * | 2005-06-27 | 2012-06-13 | 3M Innovative Properties Company | Microneedle array applicator device |
ATE477833T1 (de) | 2005-06-27 | 2010-09-15 | 3M Innovative Properties Co | Mikronadelkartuschenanordnung |
CN101267896A (zh) * | 2005-09-12 | 2008-09-17 | 阿尔扎公司 | 可涂覆的透皮给药微突起组合件 |
WO2007061964A1 (en) * | 2005-11-18 | 2007-05-31 | 3M Innovative Properties Company | Methods for coating microneedles |
US20080262416A1 (en) * | 2005-11-18 | 2008-10-23 | Duan Daniel C | Microneedle Arrays and Methods of Preparing Same |
US20110107473A1 (en) * | 2006-03-15 | 2011-05-05 | Wisconsin Alumni Research Foundation | Diamond-like carbon coated nanoprobes |
US20080142709A1 (en) * | 2006-03-21 | 2008-06-19 | Anirudha Vishwanath Sumant | MONOLITHIC ta-C NANOPROBES AND ta-C COATED NANOPROBES |
WO2007116409A2 (en) * | 2006-04-11 | 2007-10-18 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Improved vaccines comprising multimeric hsp60 peptide carriers |
WO2007124411A1 (en) * | 2006-04-20 | 2007-11-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
US20080214987A1 (en) * | 2006-12-22 | 2008-09-04 | Nanomed Devices, Inc. | Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances |
US10525246B2 (en) | 2006-12-22 | 2020-01-07 | Nanomed Skincare, Inc. | Microdevice and method for transdermal delivery and sampling of active substances |
US20080226724A1 (en) * | 2007-01-19 | 2008-09-18 | Genentech, Inc. | Prevention of hydrogel viscosity loss |
US8821446B2 (en) * | 2007-01-22 | 2014-09-02 | Corium International, Inc. | Applicators for microneedles |
EP2146689B1 (en) | 2007-04-16 | 2020-08-12 | Corium, Inc. | Solvent-cast microneedle arrays containing active |
WO2009048607A1 (en) | 2007-10-10 | 2009-04-16 | Corium International, Inc. | Vaccine delivery via microneedle arrays |
US9107815B2 (en) * | 2008-02-22 | 2015-08-18 | Allergan, Inc. | Sustained release poloxamer containing pharmaceutical compositions |
KR101634836B1 (ko) * | 2008-12-26 | 2016-06-29 | 히사미쓰 세이야꾸 가부시키가이샤 | 마이크로 니들 디바이스 |
KR101136739B1 (ko) * | 2009-06-15 | 2012-04-19 | 주식회사 라파스 | 다기능 하이브리드 마이크로구조체 및 그의 제조방법 |
PL2512446T3 (pl) * | 2009-12-16 | 2015-08-31 | Shasun Pharmaceuticals Ltd | Kompozycja transdermalnego hydrożelu z deksibuprofenem |
CA2798145C (en) | 2010-05-04 | 2022-10-18 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
GB201120000D0 (en) * | 2011-11-20 | 2012-01-04 | Glaxosmithkline Biolog Sa | Vaccine |
GB201119999D0 (en) * | 2011-11-20 | 2012-01-04 | Glaxosmithkline Biolog Sa | Vaccine |
AU2013364053B2 (en) | 2012-12-21 | 2018-08-30 | Corium Pharma Solutions, Inc. | Microarray for delivery of therapeutic agent and methods of use |
CN105142711B (zh) | 2013-03-12 | 2019-01-22 | 考里安国际公司 | 微突起施加器 |
US10384045B2 (en) | 2013-03-15 | 2019-08-20 | Corium, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
JP6689187B2 (ja) | 2013-03-15 | 2020-04-28 | コリウム, インコーポレイテッド | 複数の衝突微小突起アプリケータおよび使用方法 |
CA2906541C (en) | 2013-03-15 | 2022-06-21 | Corium International, Inc. | Microarray for delivery of therapeutic agent and methods of use |
US20160310412A1 (en) * | 2013-12-16 | 2016-10-27 | Takeda Pharmaceutical Company Limited | Microneedle |
US10624843B2 (en) | 2014-09-04 | 2020-04-21 | Corium, Inc. | Microstructure array, methods of making, and methods of use |
US10537723B2 (en) | 2014-09-11 | 2020-01-21 | Hisamitsu Pharmaceutical Co., Inc. | Microneedle device |
KR101626053B1 (ko) * | 2014-09-19 | 2016-06-01 | 연세대학교 산학협력단 | 원터치 유체 채취용 디바이스 |
SG11201702779PA (en) | 2014-10-27 | 2017-05-30 | Hisamitsu Pharmaceutical Co | Microneedle device containing recombinant follicle stimulating hormone |
US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
MX2019002835A (es) | 2016-09-13 | 2019-09-04 | Allergan Inc | Composiciones no proteínicas de toxina clostridial. |
KR102225666B1 (ko) * | 2018-12-31 | 2021-03-11 | 서울시립대학교 산학협력단 | 핵산 기반 마이크로니들의 제조방법 및 이를 통해 제조된 핵산 기반 마이크로니들 |
US20240181036A1 (en) * | 2020-04-22 | 2024-06-06 | Emergex USA Corporation | Transdermal active agent delivery devices having coronavirus vaccine coated micro-protrusions |
CN116407624B (zh) * | 2023-04-14 | 2024-04-09 | 吉林省农业科学院(中国农业科技东北创新中心) | 一种鸡传染性支气管炎细菌样颗粒疫苗的制备方法和应用 |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE25637E (en) * | 1964-09-08 | Means for vaccinating | ||
US3136314A (en) * | 1960-08-01 | 1964-06-09 | Kravitz Harvey | Vaccinating devices |
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
BE795384A (fr) * | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
OA05448A (fr) * | 1975-10-16 | 1981-03-31 | Manufrance Manufacture Francai | Dispositif vaccinateur multipénétrant. |
FR2474856A1 (fr) * | 1980-01-31 | 1981-08-07 | Merieux Inst | Dispositif scarificateur |
EP0429842B1 (en) * | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US5487726A (en) * | 1994-06-16 | 1996-01-30 | Ryder International Corporation | Vaccine applicator system |
AU5740496A (en) * | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
DK0914178T3 (da) * | 1996-06-18 | 2003-04-22 | Alza Corp | Anordning til forøgelse af transdermal afgivelse eller prøveudtagning af et middel |
US5916524A (en) * | 1997-07-23 | 1999-06-29 | Bio-Dot, Inc. | Dispensing apparatus having improved dynamic range |
US5738728A (en) * | 1996-07-26 | 1998-04-14 | Bio Dot, Inc. | Precision metered aerosol dispensing apparatus |
US5741554A (en) * | 1996-07-26 | 1998-04-21 | Bio Dot, Inc. | Method of dispensing a liquid reagent |
US5743960A (en) * | 1996-07-26 | 1998-04-28 | Bio-Dot, Inc. | Precision metered solenoid valve dispenser |
EP0934093B1 (en) * | 1996-09-17 | 2003-01-15 | Deka Products Limited Partnership | System for delivery of drugs by transport |
US6918901B1 (en) * | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
AU739616B2 (en) * | 1997-12-11 | 2001-10-18 | Alza Corporation | Device for enhancing transdermal agent flux |
ES2244106T3 (es) * | 1997-12-11 | 2005-12-01 | Alza Corporation | Dispositivo para mejorar el flujo transdermico de agentes. |
JP2001525227A (ja) * | 1997-12-11 | 2001-12-11 | アルザ・コーポレーション | 経皮的薬剤流量を高めるための装置 |
US6091975A (en) * | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
US6203051B1 (en) * | 1999-03-23 | 2001-03-20 | Jeffrey P. Sabol | Safety rotatable snowboard boot binding |
GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
AU8346901A (en) * | 2000-08-24 | 2002-03-04 | Alza Corp | Method for transdermal nucleic acid sampling |
DE60129585T2 (de) * | 2000-09-08 | 2008-04-17 | Alza Corp., Mountain View | Transdermale vorrichtung |
CZ20031037A3 (cs) * | 2000-10-13 | 2003-10-15 | Alza Corporation | Zařízení a způsob probodnutí kůže mikrovýčnělky |
EP1341442B1 (en) * | 2000-10-13 | 2005-06-29 | Alza Corporation | Microblade array impact applicator |
BR0114628A (pt) * | 2000-10-13 | 2004-01-20 | Alza Corp | Membro de retenção em microprojeção para aplicador de impacto |
JP4659336B2 (ja) * | 2000-10-26 | 2011-03-30 | アルザ・コーポレーシヨン | 被覆された微細突出物を有する経皮的薬剤配達装置 |
US6855372B2 (en) * | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
CN101129327A (zh) * | 2001-04-20 | 2008-02-27 | 阿尔扎公司 | 具有包含有益药剂的涂层的微小突出物阵列 |
US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
US20030199810A1 (en) * | 2001-11-30 | 2003-10-23 | Trautman Joseph Creagan | Methods and apparatuses for forming microprojection arrays |
DK1465535T3 (da) * | 2001-12-20 | 2008-04-07 | Alza Corp | Mikrofremspring til gennemstikning af huden med stikdybdestyring |
AR040302A1 (es) * | 2002-06-28 | 2005-03-23 | Alza Corp | Dispositivos para la liberacion transdermica de farmacos, que presentan microprotrusiones recubiertas |
TW200409657A (en) * | 2002-08-08 | 2004-06-16 | Alza Corp | Transdermal vaccine delivery device having coated microprotrusions |
WO2004030743A2 (en) * | 2002-09-30 | 2004-04-15 | Alza Corporation | Drug delivery device having coated microprojections incorporating vasoconstrictors |
AR042815A1 (es) * | 2002-12-26 | 2005-07-06 | Alza Corp | Dispositivo de suministro de agente activo que tiene miembros compuestos |
ES2437565T3 (es) * | 2003-06-30 | 2014-01-13 | Alza Corporation | Formulaciones para microproyecciones revestidas que contienen contraiones no volátiles |
WO2005041871A2 (en) * | 2003-10-24 | 2005-05-12 | Alza Corporation | Apparatus and method for enhancing transdermal drug delivery |
EP1675539A4 (en) * | 2003-10-24 | 2007-09-12 | Alza Corp | METHOD AND SYSTEM FOR PRETREATMENT FOR IMPROVING TRANSDERMAL DRUG DELIVERY |
-
2004
- 2004-07-01 TW TW093119875A patent/TW200513280A/zh unknown
- 2004-07-01 PE PE2004000631A patent/PE20050288A1/es not_active Application Discontinuation
- 2004-07-01 JP JP2006518804A patent/JP2007521092A/ja active Pending
- 2004-07-01 KR KR1020067000059A patent/KR20060037320A/ko not_active Application Discontinuation
- 2004-07-01 AU AU2004253571A patent/AU2004253571A1/en not_active Abandoned
- 2004-07-01 CN CNA2004800251396A patent/CN1845708A/zh active Pending
- 2004-07-01 AR ARP040102324A patent/AR044985A1/es not_active Application Discontinuation
- 2004-07-01 WO PCT/US2004/021393 patent/WO2005002453A1/en active Application Filing
- 2004-07-01 BR BRPI0412202-0A patent/BRPI0412202A/pt not_active IP Right Cessation
- 2004-07-01 UY UY28398A patent/UY28398A1/es unknown
- 2004-07-01 EP EP04756609A patent/EP1643918A1/en not_active Withdrawn
- 2004-07-01 US US10/884,603 patent/US20050025778A1/en not_active Abandoned
- 2004-07-01 CA CA002530954A patent/CA2530954A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2007521092A (ja) | 2007-08-02 |
KR20060037320A (ko) | 2006-05-03 |
WO2005002453A1 (en) | 2005-01-13 |
CA2530954A1 (en) | 2005-01-13 |
UY28398A1 (es) | 2004-11-08 |
AU2004253571A1 (en) | 2005-01-13 |
BRPI0412202A (pt) | 2006-08-22 |
CN1845708A (zh) | 2006-10-11 |
US20050025778A1 (en) | 2005-02-03 |
TW200513280A (en) | 2005-04-16 |
EP1643918A1 (en) | 2006-04-12 |
PE20050288A1 (es) | 2005-04-29 |
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