AR040717A1 - Uso de alquilfosfocolinas en cominacion con medicamentos antitumorales para el tratamiento de oncosis maligna y benigna en seres humanos y animales - Google Patents
Uso de alquilfosfocolinas en cominacion con medicamentos antitumorales para el tratamiento de oncosis maligna y benigna en seres humanos y animalesInfo
- Publication number
- AR040717A1 AR040717A1 AR20030102710A ARP030102710A AR040717A1 AR 040717 A1 AR040717 A1 AR 040717A1 AR 20030102710 A AR20030102710 A AR 20030102710A AR P030102710 A ARP030102710 A AR P030102710A AR 040717 A1 AR040717 A1 AR 040717A1
- Authority
- AR
- Argentina
- Prior art keywords
- treatment
- alkyl
- oncosis
- alkylamino
- radical
- Prior art date
Links
- 241001465754 Metazoa Species 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 230000021603 oncosis Effects 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 title 1
- -1 alkyl phosphocholines Chemical class 0.000 abstract 6
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 229940041181 antineoplastic drug Drugs 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 230000003211 malignant effect Effects 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 239000000824 cytostatic agent Substances 0.000 abstract 1
- 230000001085 cytostatic effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39961502P | 2002-07-30 | 2002-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR040717A1 true AR040717A1 (es) | 2005-04-20 |
Family
ID=31495746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR20030102710A AR040717A1 (es) | 2002-07-30 | 2003-07-29 | Uso de alquilfosfocolinas en cominacion con medicamentos antitumorales para el tratamiento de oncosis maligna y benigna en seres humanos y animales |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US8389497B2 (OSRAM) |
| EP (2) | EP1545553B1 (OSRAM) |
| JP (1) | JP2005535688A (OSRAM) |
| KR (3) | KR20110102485A (OSRAM) |
| CN (1) | CN1302780C (OSRAM) |
| AR (1) | AR040717A1 (OSRAM) |
| AT (1) | ATE516036T1 (OSRAM) |
| AU (2) | AU2003253350B2 (OSRAM) |
| BR (1) | BR0313048A (OSRAM) |
| CA (1) | CA2493023C (OSRAM) |
| CY (1) | CY1111902T1 (OSRAM) |
| DK (1) | DK1545553T3 (OSRAM) |
| ES (1) | ES2369535T3 (OSRAM) |
| HR (1) | HRP20050184B1 (OSRAM) |
| IL (1) | IL166329A (OSRAM) |
| MX (1) | MXPA05001203A (OSRAM) |
| NO (1) | NO335196B1 (OSRAM) |
| NZ (1) | NZ538428A (OSRAM) |
| PL (1) | PL375493A1 (OSRAM) |
| PT (1) | PT1545553E (OSRAM) |
| RU (1) | RU2005105693A (OSRAM) |
| SI (1) | SI1545553T1 (OSRAM) |
| TW (1) | TWI332007B (OSRAM) |
| UA (1) | UA82322C2 (OSRAM) |
| WO (1) | WO2004012744A1 (OSRAM) |
| ZA (1) | ZA200500453B (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ538428A (en) | 2002-07-30 | 2006-09-29 | Zentaris Gmbh | Use of alkylphosphocholines in combination with antitumor medicaments |
| US8383605B2 (en) | 2002-07-30 | 2013-02-26 | Aeterna Zentaris Gmbh | Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals |
| DE10324911B4 (de) | 2003-05-30 | 2005-08-18 | Siemens Ag | Röntgenvorrichtung mit partiellem digitalem Detektor und Verfahren zum Betrieb einer solchen |
| WO2006081452A2 (en) * | 2005-01-28 | 2006-08-03 | Robert Birch | Co-administration of perifosine with chemotherapeutics |
| KR101378005B1 (ko) | 2005-12-19 | 2014-03-27 | 아에테르나 젠타리스 게엠베하 | 세포독성이 감소된 알킬 인지질 유도체 및 이의 용도 |
| US20070167408A1 (en) * | 2005-12-19 | 2007-07-19 | Zentaris Gmbh | Novel alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof |
| EP1800684A1 (en) * | 2005-12-20 | 2007-06-27 | Zentaris GmbH | Novel alkyl phospholipid derivatives and uses thereof |
| US8703179B2 (en) | 2006-05-11 | 2014-04-22 | Kimberly-Clark Worldwide, Inc. | Mucosal formulation |
| KR20100092424A (ko) * | 2007-07-30 | 2010-08-20 | 아디아 바이오사이언스즈 인크. | 다형체를 포함하는, ｍｅｋ의 억제제로서의 ｎ-(아릴아미노) 술폰아미드의 유도체 및 조성물, 사용 방법 및 이의 제조 방법 |
| AU2009324464B2 (en) * | 2008-12-11 | 2016-05-05 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| CA2794513A1 (en) | 2010-03-31 | 2011-10-06 | Aeterna Zentaris Gmbh | Perifosine and capecitabine as a combined treatment for cancer |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE59205998D1 (de) * | 1991-07-04 | 1996-05-23 | Asta Medica Ag | Arzneimittel mit antineoplastischer Wirkung enthaltend als Wirkstoff Octadecyl-[2-(N-methylpiperidino)-ethyl]-phosphat und Verfahren zu dessen Herstellung |
| US5942639A (en) * | 1991-07-04 | 1999-08-24 | Asta Medica Aktiengesellschaft | Process for the preparation of alkylphosphocholines and the production thereof in pure form |
| US6172050B1 (en) * | 1992-07-11 | 2001-01-09 | Asta Medica Aktiengesellschaft | Phospholipid derivatives |
| JP3079993B2 (ja) * | 1996-03-27 | 2000-08-21 | 日本電気株式会社 | 真空マイクロデバイスおよびその製造方法 |
| DE19650778C2 (de) * | 1996-12-06 | 2001-01-04 | Asta Medica Ag | Verwendung von Dopaminrezeptor-Antagonisten in der palliativen Tumortherapie |
| SK284839B6 (sk) | 1998-01-22 | 2005-12-01 | Zentaris Gmbh | Použitie miltefozínu na výrobu lieku a farmaceutická kombinácia na liečenie leishmanózy |
| EP1135193B1 (de) * | 1998-12-04 | 2002-10-30 | Max-Delbrück-Centrum Für Molekulare Medizin | Mittel zur tumortherapie auf liposomenbasis, die tamoxifen enthalten |
| JP2002532553A (ja) * | 1998-12-21 | 2002-10-02 | インケイサ．ソシエダ アノニマ | 有害な胃腸副作用を引き起こさない有力な抗炎症剤としてのエーテルリゾリン脂質の使用 |
| LT3351246T (lt) * | 2001-02-19 | 2019-07-10 | Novartis Pharma Ag | Rapamicino darinys, skirtas kieto naviko, susijusio su nereguliuojama angiogeneze, gydymui |
| DE60234577D1 (de) * | 2001-03-23 | 2010-01-14 | Shire Canada Inc | Pharmazeutische mischung zur behandlung von krebs, die dioxolan nukleosidanalogen enthält |
| WO2003005522A1 (es) | 2001-07-04 | 2003-01-16 | Acuna Arturo | Tapones para sellado de ductos para redes electricas, telefonicas y de fibra optica. |
| DK1461083T3 (da) * | 2002-01-02 | 2006-07-10 | Nerviano Medical Sciences Srl | Kombineret terapi mod tumorer omfattende substitueret acryloyl distamycinderivater og proteinkinase- (serin/threoninkinase) inhibitorer |
| NZ538428A (en) | 2002-07-30 | 2006-09-29 | Zentaris Gmbh | Use of alkylphosphocholines in combination with antitumor medicaments |
| WO2005000318A2 (en) * | 2003-06-23 | 2005-01-06 | Neopharm, Inc. | Method of inducing apoptosis and inhibiting cardiolipin synthesis |
| WO2006081452A2 (en) | 2005-01-28 | 2006-08-03 | Robert Birch | Co-administration of perifosine with chemotherapeutics |
| US20070167408A1 (en) * | 2005-12-19 | 2007-07-19 | Zentaris Gmbh | Novel alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof |
| CA2794513A1 (en) | 2010-03-31 | 2011-10-06 | Aeterna Zentaris Gmbh | Perifosine and capecitabine as a combined treatment for cancer |
-
2003
- 2003-07-29 NZ NZ538428A patent/NZ538428A/en not_active IP Right Cessation
- 2003-07-29 WO PCT/EP2003/008346 patent/WO2004012744A1/de not_active Ceased
- 2003-07-29 HR HRP20050184AA patent/HRP20050184B1/hr not_active IP Right Cessation
- 2003-07-29 TW TW092120705A patent/TWI332007B/zh not_active IP Right Cessation
- 2003-07-29 EP EP03766336A patent/EP1545553B1/de not_active Expired - Lifetime
- 2003-07-29 KR KR1020117017914A patent/KR20110102485A/ko not_active Ceased
- 2003-07-29 DK DK03766336.6T patent/DK1545553T3/da active
- 2003-07-29 AT AT03766336T patent/ATE516036T1/de active
- 2003-07-29 ES ES03766336T patent/ES2369535T3/es not_active Expired - Lifetime
- 2003-07-29 UA UAA200500510A patent/UA82322C2/uk unknown
- 2003-07-29 PL PL03375493A patent/PL375493A1/xx unknown
- 2003-07-29 AR AR20030102710A patent/AR040717A1/es unknown
- 2003-07-29 BR BR0313048-7A patent/BR0313048A/pt not_active IP Right Cessation
- 2003-07-29 CA CA2493023A patent/CA2493023C/en not_active Expired - Lifetime
- 2003-07-29 SI SI200332027T patent/SI1545553T1/sl unknown
- 2003-07-29 PT PT03766336T patent/PT1545553E/pt unknown
- 2003-07-29 KR KR1020057001510A patent/KR101066804B1/ko not_active Expired - Lifetime
- 2003-07-29 EP EP10010451A patent/EP2301551A1/de not_active Withdrawn
- 2003-07-29 JP JP2004525354A patent/JP2005535688A/ja active Pending
- 2003-07-29 CN CNB038181010A patent/CN1302780C/zh not_active Expired - Fee Related
- 2003-07-29 KR KR1020127034433A patent/KR20130016413A/ko not_active Ceased
- 2003-07-29 RU RU2005105693/15A patent/RU2005105693A/ru unknown
- 2003-07-29 AU AU2003253350A patent/AU2003253350B2/en not_active Ceased
- 2003-07-29 MX MXPA05001203A patent/MXPA05001203A/es active IP Right Grant
- 2003-07-30 US US10/632,187 patent/US8389497B2/en not_active Expired - Fee Related
-
2005
- 2005-01-17 IL IL166329A patent/IL166329A/en not_active IP Right Cessation
- 2005-01-18 ZA ZA2005/00453A patent/ZA200500453B/en unknown
- 2005-02-25 NO NO20051040A patent/NO335196B1/no not_active IP Right Cessation
-
2008
- 2008-07-10 AU AU2008203060A patent/AU2008203060B2/en not_active Ceased
-
2010
- 2010-03-31 US US12/751,608 patent/US8507710B2/en not_active Expired - Fee Related
- 2010-03-31 US US12/751,454 patent/US8551977B2/en not_active Expired - Fee Related
-
2011
- 2011-09-30 CY CY20111100944T patent/CY1111902T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2152222T3 (es) | Sulfonamidas, su preparacion y su uso como medicamento e intermedio. | |
| AR040717A1 (es) | Uso de alquilfosfocolinas en cominacion con medicamentos antitumorales para el tratamiento de oncosis maligna y benigna en seres humanos y animales | |
| UY27875A1 (es) | Prodrogas 2 ' y 3 ' de nucleósidos modificados para tratar flaviviridae | |
| UY27186A1 (es) | Formulación farmacéutica | |
| CY1105407T1 (el) | Αλδονικα οξεα ολιγοσακχαριτων και η τοπικη τους χρηση | |
| DE60336664D1 (de) | Nichtnukleosidische reverse-transkriptase-hemmer | |
| CY1116463T1 (el) | Θεραπεια συνδυασμου για τη θεραπευτικη αγωγη διαταραχων ανεπαρκειας πρωτεϊνης | |
| DE60033684D1 (de) | Phenylalaninderivate | |
| ECSP055609A (es) | "Uso de inhibidores de la IkB-quinasa para el tratamiento del dolor" | |
| CY1111872T1 (el) | Συνθεσεις υποτασικου λιπιδιου (προσταγλανδινης) και τιμολολης - σχετικες μεθοδοι χρησης | |
| SE8800731D0 (sv) | Phenyl carbamate | |
| CY1111613T1 (el) | Μεθοδοι για την αντιμετωπιση της μολυνσης απο hiv | |
| ES2096673T3 (es) | Uso de sulfonamidas como medicamentos y nuevas sulfonamidas. | |
| DE3381396D1 (de) | Formulierung nicht irritierender ophthalmischer waesseriger zusammensetzungen fuer okular-therapeutische mittel. | |
| CY1109286T1 (el) | Σκευασμα τυπου φυραματος που περιλαμβανουν διοξειδιο πυριτιου | |
| TR200102313T2 (tr) | Antiviral maddeler olarak (1R, SíS)-4-(6-amino-9H-purin-9-il)-2-siklopenten-1-metanoln mono-, di ve tri-fosfat esterleri ve fosforamidatlarì | |
| CY1106771T1 (el) | Φαρμακευτικη συνθεση η οποια χρησιμοποιειται για τον ελεγχο της γλυκοζης του αιματος σε ασθενεις με διαβητη τυπου 2 | |
| PE20050822A1 (es) | Derivados de florfenicol con mejor solubilidad en agua | |
| NO20022599L (no) | Klorofyll- og bakterioklorofyllestere, deres fremstilling og farmasöytiske sammensetninger som innbefatter slike | |
| ES2061546T3 (es) | Compuestos quelantes de piridoxamina, quelatos de manganeso (ii) y su uso como agentes de contraste de nmri. | |
| TR200400526T4 (tr) | Göz kurumasının tedavisi için lipoksin A4 ve analogları | |
| UY28356A1 (es) | Derivados de benzimidazol, composiciones que los contienen, preparaciones de los mismos y sus usos | |
| ES2036526T3 (es) | Composiciones de interferon. | |
| DK0773782T3 (da) | Terpenderivater (sarcodictyiner) anvendelse som antitumormidler | |
| ES2052484T1 (es) | N-(5-tioxo-l-prolil)-l-cisteina, sus derivados, procedimientos para su preparacion y composiciones farmaceuticas que los contienen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |