AR037261A1 - Amidas de acido antranilico, un proceso para su preparacion, composiciones farmaceuticas, y el uso de dichas amidas para la preaparacion de un medicamento - Google Patents
Amidas de acido antranilico, un proceso para su preparacion, composiciones farmaceuticas, y el uso de dichas amidas para la preaparacion de un medicamentoInfo
- Publication number
- AR037261A1 AR037261A1 ARP020104236A ARP020104236A AR037261A1 AR 037261 A1 AR037261 A1 AR 037261A1 AR P020104236 A ARP020104236 A AR P020104236A AR P020104236 A ARP020104236 A AR P020104236A AR 037261 A1 AR037261 A1 AR 037261A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- amidas
- alkyl
- pharmaceutical compositions
- alkenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/40—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Abstract
Derivados de amida de ácido antranílico de la fórmula (1) en donde Ar está representado por la fórmula (2) en donde Ra representa H ó alquilo inferior; R1 representa H ó perfluoroalquilo inferior; y R2 representa H, halógeno, alquilo C2-7, alquenilo C2-7, o alquinilo inferior; ó Ar está representado por la subfórmula (3), y R1 representa perfluoroalquilo inferior, y R2 representa bromo, yodo, alquilo C2-7, alquenilo C2-7, ó alquinilo inferior, o R1 representa H, y R2 representa flúor, bromo, yodo, etilo, alquilo C5-7, alquenilo C2-7, ó alquinilo inferior; N-óxidos y tautómeros de los mismos, y sales de estas amidas de ácido antranílico, sus N-óxidos y tautómeros; procesos para su preparación; composiciones farmacéuticas y el uso de este compuesto, solo o en combinación con uno o más compuestos farmacéuticamente activos diferentes, para la preparación de una composición farmacéutica para el tratamiento de una enfermedad neoplásica, de retinopatía o degeneración macular relacionada con la edad.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0126901.8A GB0126901D0 (en) | 2001-11-08 | 2001-11-08 | Organic compounds |
GBGB0212917.9A GB0212917D0 (en) | 2001-11-08 | 2002-06-05 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
AR037261A1 true AR037261A1 (es) | 2004-11-03 |
Family
ID=26246753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020104236A AR037261A1 (es) | 2001-11-08 | 2002-11-06 | Amidas de acido antranilico, un proceso para su preparacion, composiciones farmaceuticas, y el uso de dichas amidas para la preaparacion de un medicamento |
Country Status (25)
Country | Link |
---|---|
US (1) | US7067543B2 (es) |
EP (2) | EP1446381B1 (es) |
JP (1) | JP4179989B2 (es) |
KR (1) | KR100633814B1 (es) |
CN (1) | CN100467450C (es) |
AR (1) | AR037261A1 (es) |
AT (1) | ATE494278T1 (es) |
AU (1) | AU2002342889B2 (es) |
BR (1) | BR0213939A (es) |
CA (1) | CA2462390C (es) |
DE (1) | DE60238856D1 (es) |
GB (2) | GB0126901D0 (es) |
HR (1) | HRP20040412A2 (es) |
IL (1) | IL161163A0 (es) |
MX (1) | MXPA04004390A (es) |
MY (1) | MY136322A (es) |
NO (1) | NO326986B1 (es) |
NZ (1) | NZ532587A (es) |
PE (1) | PE20030540A1 (es) |
PL (1) | PL368417A1 (es) |
PT (1) | PT1446381E (es) |
RS (1) | RS29404A (es) |
RU (1) | RU2315756C2 (es) |
TW (1) | TWI260985B (es) |
WO (1) | WO2003040101A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7307088B2 (en) | 2002-07-09 | 2007-12-11 | Amgen Inc. | Substituted anthranilic amide derivatives and methods of use |
GB0229022D0 (en) * | 2002-12-12 | 2003-01-15 | Novartis Ag | Organic Compounds |
UA89035C2 (ru) | 2003-12-03 | 2009-12-25 | Лео Фарма А/С | Эфиры гидроксамовых кислот и их фармацевтическое применение |
ES2619203T3 (es) | 2004-01-28 | 2017-06-23 | Mitsui Chemicals Agro, Inc. | Derivados de amida, procesos para la producción de los mismos y método para su aplicación como insecticidas |
DE102004009238A1 (de) * | 2004-02-26 | 2005-09-08 | Merck Patent Gmbh | Arylamid-Derivate |
JPWO2006070878A1 (ja) * | 2004-12-28 | 2008-06-12 | アステラス製薬株式会社 | カルボン酸誘導体またはその塩 |
EP2145873A1 (fr) * | 2008-06-17 | 2010-01-20 | Commissariat A L'energie Atomique | Nouveaux composés ayant une activité protectrice vis-à-vis de l'action de toxines et de virus au mode d'action intracellulaire |
AU2009287152B2 (en) | 2008-08-27 | 2014-09-25 | Leo Pharma A/S | Pyridine derivatives as VEGFR-2 receptor and protein tyrosine kinase inhibitors |
JP2011057661A (ja) * | 2009-08-14 | 2011-03-24 | Bayer Cropscience Ag | 殺虫性カルボキサミド類 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3226394A (en) * | 1964-06-16 | 1965-12-28 | Shulton Inc | Pyridylethylated anthranilamides and derivatives thereof |
WO1998014449A1 (en) | 1996-10-02 | 1998-04-09 | Novartis Ag | Fused pyrazole derivatives and processes for their preparation |
GB9824579D0 (en) * | 1998-11-10 | 1999-01-06 | Novartis Ag | Organic compounds |
-
2001
- 2001-11-08 GB GBGB0126901.8A patent/GB0126901D0/en not_active Ceased
-
2002
- 2002-06-05 GB GBGB0212917.9A patent/GB0212917D0/en not_active Ceased
- 2002-11-06 PE PE2002001081A patent/PE20030540A1/es not_active Application Discontinuation
- 2002-11-06 AR ARP020104236A patent/AR037261A1/es not_active Application Discontinuation
- 2002-11-06 TW TW091132668A patent/TWI260985B/zh active
- 2002-11-07 EP EP02779536A patent/EP1446381B1/en not_active Expired - Lifetime
- 2002-11-07 US US10/494,222 patent/US7067543B2/en not_active Expired - Fee Related
- 2002-11-07 BR BR0213939-1A patent/BR0213939A/pt not_active IP Right Cessation
- 2002-11-07 JP JP2003542147A patent/JP4179989B2/ja not_active Expired - Fee Related
- 2002-11-07 NZ NZ532587A patent/NZ532587A/en not_active IP Right Cessation
- 2002-11-07 EP EP10180423A patent/EP2269988B1/en not_active Expired - Lifetime
- 2002-11-07 AT AT02779536T patent/ATE494278T1/de active
- 2002-11-07 MY MYPI20024160A patent/MY136322A/en unknown
- 2002-11-07 PL PL02368417A patent/PL368417A1/xx not_active Application Discontinuation
- 2002-11-07 CN CNB028214307A patent/CN100467450C/zh not_active Expired - Fee Related
- 2002-11-07 WO PCT/EP2002/012445 patent/WO2003040101A1/en active IP Right Grant
- 2002-11-07 KR KR1020047007000A patent/KR100633814B1/ko not_active IP Right Cessation
- 2002-11-07 MX MXPA04004390A patent/MXPA04004390A/es active IP Right Grant
- 2002-11-07 AU AU2002342889A patent/AU2002342889B2/en not_active Ceased
- 2002-11-07 RU RU2004117548/04A patent/RU2315756C2/ru not_active IP Right Cessation
- 2002-11-07 PT PT02779536T patent/PT1446381E/pt unknown
- 2002-11-07 IL IL16116302A patent/IL161163A0/xx unknown
- 2002-11-07 DE DE60238856T patent/DE60238856D1/de not_active Expired - Lifetime
- 2002-11-07 CA CA2462390A patent/CA2462390C/en not_active Expired - Fee Related
- 2002-11-07 RS YUP-294/04A patent/RS29404A/sr unknown
-
2004
- 2004-05-07 HR HR20040412A patent/HRP20040412A2/hr not_active Application Discontinuation
- 2004-05-25 NO NO20042137A patent/NO326986B1/no not_active IP Right Cessation
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Legal Events
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FC | Refusal |