AR036304A1 - Sistema nuevo de liberacion de droga autoemulsionable - Google Patents
Sistema nuevo de liberacion de droga autoemulsionableInfo
- Publication number
- AR036304A1 AR036304A1 ARP020103215A ARP020103215A AR036304A1 AR 036304 A1 AR036304 A1 AR 036304A1 AR P020103215 A ARP020103215 A AR P020103215A AR P020103215 A ARP020103215 A AR P020103215A AR 036304 A1 AR036304 A1 AR 036304A1
- Authority
- AR
- Argentina
- Prior art keywords
- proton pump
- pump inhibitor
- pharmaceutical composition
- composition
- drug release
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Composición farmacéutica adecuada para la administración oral, en la forma de un pre-concentrado de emulsión, que comprende: (i) uno o más NSAID(s) que liberan NO; ii) uno o más surfactantes de los cuales, al menos uno es un fosfolípido; dicha composición forma una emulsión aceite en agua in situ luego del contacto con los fluidos gastrointestinales. Opcionalmente, la composición puede también comprender un aceite adicional o grasa semi-sólida. Se pueden incluir uno o más alcoholes de cadena corta en la composición. Una combinación con un inhibidor de la bomba de protones. La composición farmacéutica es útil para el tratamiento del dolor y la inflamación. Un kit que comprende una composición farmacéutica de acuerdo con la presente en una forma de dosis unitaria, combinada con un inhibidor de la bomba de protones, dicho inhibidor de la bomba de protones tiene un revestimiento entérico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0102993A SE0102993D0 (sv) | 2001-09-07 | 2001-09-07 | New self emulsifying drug delivery system |
Publications (1)
Publication Number | Publication Date |
---|---|
AR036304A1 true AR036304A1 (es) | 2004-08-25 |
Family
ID=20285273
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020103215A AR036304A1 (es) | 2001-09-07 | 2002-08-27 | Sistema nuevo de liberacion de droga autoemulsionable |
Country Status (9)
Country | Link |
---|---|
US (1) | US7815933B2 (es) |
EP (1) | EP1427392B1 (es) |
JP (1) | JP4656483B2 (es) |
AR (1) | AR036304A1 (es) |
AT (1) | ATE386503T1 (es) |
DE (1) | DE60225154T2 (es) |
ES (1) | ES2300471T3 (es) |
SE (1) | SE0102993D0 (es) |
WO (1) | WO2003022249A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
IT1319202B1 (it) | 2000-10-12 | 2003-09-26 | Nicox Sa | Farmaci per le malattie a base infiammatoria. |
CA2491127A1 (en) | 2002-07-03 | 2004-01-15 | Nitromed, Inc. | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use |
CA2493156A1 (en) | 2002-07-29 | 2004-02-05 | Nitromed, Inc. | Cyclooxygenase-2 selective inhibitors, compositions and methods of use |
JP4634144B2 (ja) | 2002-08-01 | 2011-02-16 | ニコックス エスエー | ニトロソ化プロトンポンプ阻害剤、組成物および使用方法 |
SE0301880D0 (sv) * | 2003-06-25 | 2003-06-25 | Astrazeneca Uk Ltd | New drug delivery composition |
GB0818473D0 (en) * | 2008-10-08 | 2008-11-12 | Probio Nutraceuticals As | Composition |
US9968557B1 (en) | 2011-02-09 | 2018-05-15 | Florida A&M University | Method of preparing modified multilayered microstructures with enhanced oral bioavailability |
US20120213855A1 (en) * | 2011-02-17 | 2012-08-23 | Cima Labs Inc. | Dosage forms for weakly ionizable compounds |
WO2013142482A1 (en) | 2012-03-20 | 2013-09-26 | Particle Dynamics International, Llc | Gelling agent-based dosage form |
EP2833976A1 (en) * | 2012-04-03 | 2015-02-11 | Unilever N.V. | A personal care composition |
WO2017218894A1 (en) | 2016-06-16 | 2017-12-21 | Cutispharma, Inc. | Composition and method for proton pump inhibitor suspension |
CN110179750A (zh) * | 2019-06-17 | 2019-08-30 | 四川九章生物科技有限公司 | 一种绿原酸自乳化组合物及其用途 |
US10751333B1 (en) | 2019-07-16 | 2020-08-25 | Cutispharma, Inc. | Compositions and kits for omeprazole suspension |
US11633478B2 (en) | 2019-07-16 | 2023-04-25 | Azurity Pharmaceuticals, Inc. | Compositions and kits for Omeprazole suspension |
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SE0002476D0 (sv) | 2000-06-30 | 2000-06-30 | Astrazeneca Ab | New compounds |
US6544556B1 (en) | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
US20020045184A1 (en) | 2000-10-02 | 2002-04-18 | Chih-Ming Chen | Packaging system |
FR2818905A1 (fr) | 2000-12-28 | 2002-07-05 | Cll Pharma | Compositions pharmaceutiques colloidales micellaires renfermant un principe actif lipophile |
AR036354A1 (es) | 2001-08-31 | 2004-09-01 | Takeda Chemical Industries Ltd | Preparacion solida |
-
2001
- 2001-09-07 SE SE0102993A patent/SE0102993D0/xx unknown
-
2002
- 2002-08-27 AR ARP020103215A patent/AR036304A1/es not_active Application Discontinuation
- 2002-09-05 EP EP02765747A patent/EP1427392B1/en not_active Expired - Lifetime
- 2002-09-05 ES ES02765747T patent/ES2300471T3/es not_active Expired - Lifetime
- 2002-09-05 DE DE60225154T patent/DE60225154T2/de not_active Expired - Lifetime
- 2002-09-05 US US10/488,585 patent/US7815933B2/en not_active Expired - Fee Related
- 2002-09-05 WO PCT/SE2002/001598 patent/WO2003022249A1/en active IP Right Grant
- 2002-09-05 JP JP2003526379A patent/JP4656483B2/ja not_active Expired - Fee Related
- 2002-09-05 AT AT02765747T patent/ATE386503T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2300471T3 (es) | 2008-06-16 |
DE60225154D1 (de) | 2008-04-03 |
EP1427392B1 (en) | 2008-02-20 |
US7815933B2 (en) | 2010-10-19 |
US20040248974A1 (en) | 2004-12-09 |
JP2005504788A (ja) | 2005-02-17 |
DE60225154T2 (de) | 2009-02-26 |
SE0102993D0 (sv) | 2001-09-07 |
ATE386503T1 (de) | 2008-03-15 |
EP1427392A1 (en) | 2004-06-16 |
WO2003022249A1 (en) | 2003-03-20 |
JP4656483B2 (ja) | 2011-03-23 |
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