AR035406A1 - Procedimiento de preparacion de eletriptan - Google Patents

Procedimiento de preparacion de eletriptan

Info

Publication number
AR035406A1
AR035406A1 ARP010105858A ARP010105858A AR035406A1 AR 035406 A1 AR035406 A1 AR 035406A1 AR P010105858 A ARP010105858 A AR P010105858A AR P010105858 A ARP010105858 A AR P010105858A AR 035406 A1 AR035406 A1 AR 035406A1
Authority
AR
Argentina
Prior art keywords
eletriptan
preparation procedure
compound
formula
preparation
Prior art date
Application number
ARP010105858A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of AR035406A1 publication Critical patent/AR035406A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Un procedimiento para preparar un compuesto de fórmula (1) que comprende la hidrólisis de un compuesto de fórmula (2) procedimiento mejorado para la preparación del fármaco antimigranoso, (R)-5-(2-bencenosulfoniletil)-3-N-metilpirrolidin-2-ilmetil)-1H-indol(eletriptán), disponible en forma de sal bromhidrato.
ARP010105858A 2000-12-20 2001-12-18 Procedimiento de preparacion de eletriptan AR035406A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0031094.6A GB0031094D0 (en) 2000-12-20 2000-12-20 New Process

Publications (1)

Publication Number Publication Date
AR035406A1 true AR035406A1 (es) 2004-05-26

Family

ID=9905487

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP010105858A AR035406A1 (es) 2000-12-20 2001-12-18 Procedimiento de preparacion de eletriptan
ARP040100334A AR043016A2 (es) 2000-12-20 2004-02-03 Un compuesto antimigranico eletriptan y composicion farmaceutica que lo contiene

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP040100334A AR043016A2 (es) 2000-12-20 2004-02-03 Un compuesto antimigranico eletriptan y composicion farmaceutica que lo contiene

Country Status (20)

Country Link
EP (1) EP1373254B1 (es)
JP (1) JP2004516290A (es)
KR (1) KR20030061448A (es)
CN (1) CN1199969C (es)
AR (2) AR035406A1 (es)
AT (1) ATE308539T1 (es)
AU (1) AU2002218440A1 (es)
BR (1) BR0116324A (es)
CA (1) CA2432138C (es)
CZ (1) CZ20031640A3 (es)
DE (1) DE60114668T2 (es)
ES (1) ES2249386T3 (es)
GB (1) GB0031094D0 (es)
HU (1) HUP0302465A2 (es)
IL (1) IL155706A0 (es)
MX (1) MXPA03005569A (es)
PL (1) PL362716A1 (es)
RU (1) RU2256660C2 (es)
WO (1) WO2002050063A1 (es)
ZA (1) ZA200303446B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112440631A (zh) * 2020-11-02 2021-03-05 长城汽车股份有限公司 一种调节胎压装置、方法、系统以及车辆

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6927296B2 (en) 2003-07-23 2005-08-09 Pfizer Inc. Process
WO2008137134A2 (en) * 2007-05-01 2008-11-13 Teva Pharmaceuticals Usa, Inc. Amorphous eletriptan hydrobromide and process for preparing it and other forms of eletriptan hydrobromide
IT1393700B1 (it) * 2009-04-22 2012-05-08 F S I Fabbrica Italiana Sint Sintesi di 3-{[(2r)-1-metilpirrolidin-2-il]metil}-5-[2-(fenilsulfonil)etil]-1h-indolo
WO2011024039A1 (en) * 2009-08-25 2011-03-03 Ramesh Babu Potluri Synthesis of novel 5-(2-(phenylsulfonyl)ethyl)-1h-indole derivatives
US8754239B2 (en) 2010-01-19 2014-06-17 Sms Pharmaceuticals Limited Process for preparing eletriptan hydrobromide having α-form
WO2012004811A1 (en) * 2010-07-06 2012-01-12 Ind-Swift Laboratories Limited Process for the preparation of 5-substsituted indole derivative
JP2019502761A (ja) 2016-01-21 2019-01-31 ラボラトリオス レヴィ エセエレ （（ｒ）−３−［（−１−メチルピロリジン−２−イル）メチル］−５−（２−フェニルスルホニルエチル）−１ｈ−インドールを作製する方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU225055B1 (en) * 1990-10-15 2006-05-29 Pfizer Indole derivatives, their intermediates, process for production them and pharmaceutical compositions containing the compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112440631A (zh) * 2020-11-02 2021-03-05 长城汽车股份有限公司 一种调节胎压装置、方法、系统以及车辆

Also Published As

Publication number Publication date
EP1373254B1 (en) 2005-11-02
CN1199969C (zh) 2005-05-04
CN1487932A (zh) 2004-04-07
AR043016A2 (es) 2005-07-13
AU2002218440A1 (en) 2002-07-01
ES2249386T3 (es) 2006-04-01
CA2432138A1 (en) 2002-06-27
JP2004516290A (ja) 2004-06-03
MXPA03005569A (es) 2003-10-06
ZA200303446B (en) 2004-07-05
CA2432138C (en) 2007-05-08
BR0116324A (pt) 2003-10-14
HUP0302465A2 (hu) 2003-12-29
ATE308539T1 (de) 2005-11-15
PL362716A1 (en) 2004-11-02
EP1373254A1 (en) 2004-01-02
DE60114668D1 (de) 2005-12-08
RU2256660C2 (ru) 2005-07-20
WO2002050063A1 (en) 2002-06-27
CZ20031640A3 (cs) 2004-08-18
DE60114668T2 (de) 2006-07-20
GB0031094D0 (en) 2001-01-31
IL155706A0 (en) 2004-02-19
KR20030061448A (ko) 2003-07-18

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