AR033504A1 - Uso de 1-arilpirazoles para preparar una composicion para el control de parasitos en o sobre un animal; compuestos relacionados; y composicion que los contiene - Google Patents
Uso de 1-arilpirazoles para preparar una composicion para el control de parasitos en o sobre un animal; compuestos relacionados; y composicion que los contieneInfo
- Publication number
- AR033504A1 AR033504A1 ARP000106403A ARP000106403A AR033504A1 AR 033504 A1 AR033504 A1 AR 033504A1 AR P000106403 A ARP000106403 A AR P000106403A AR P000106403 A ARP000106403 A AR P000106403A AR 033504 A1 AR033504 A1 AR 033504A1
- Authority
- AR
- Argentina
- Prior art keywords
- optionally substituted
- alkyl
- haloalkyl
- composition
- r205r206n
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/28—Two oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Uso de una cantidad efectiva parasiticida, sustancialmente no emética de un 1-arilpirazol de formula (1) en la cual R201 es ciano, C(O)alquilo, C(S)NH2, C(NH)OR203, C(NH)SR203, alquilo, C(=NOH)NH2, C(=NNH2)NH2, C(O)NH2, C(O)NHR205, C(O)NR205R206, haloalquilo o heterociclilo del grupo (2) opcionalmente sustituido con R203; R202 es S(O)hR203 alquenilo C2-6, haloalquenilo C2-6, cicloalquilo, halocicloalquilo, cicloalquilalquilo, alquinilo C2-6, nitro o imidazol-2-ilo opcionalmente sustituido con alquilo, alcoxi, haloalquilo, halogeno, ciano y/o nitro; R203 es alquilo o haloalquilo; R204 es ûOH, R205O-, HC(O)O-, R205C(O)O-, R205OC(O)O-, NH2C(O)O-, R205NHC(O)O-, R205R206NC(O)O-, R205S(O)nC(O)O-, R206SO2O-, aril-SO2O-, oxacicloalquiloxi (C4-7), R205R206N-C(NR205)-O-, R205R206N-C(NH)-O, R205NH-C(NR205)-O-, R205NH(NH)-O-, R205N=CH-O-, R205N=C(R206)-O-, R205NH-C(S)-O-, R205R206N-C(S)-O-; R205 es alquilo, haloalquilo, cicloalquilo, halocicloalquilo, alcoxialquilo, haloalcoxialquilo, adamantilo, aminoalquilo, alquilaminoalquilo, dialquilaminoalquilo, haloalquilaminoalquilo, di(haloalquilo)aminoalquilo, arilo opcionalmente sustituido, hetarilo, opcionalmente sustituido, arilalquilo opcionalmente sustituido, hetarilalquilo opcionalmente sustituido, alquenilo C2-6, alquinilo C2-6; R206 es alquilo, haloalquilo, cicloalquilo, halocicloalquilo, alcoxialquilo, haloalcoxialquilo, arilo, opcionalmente sustituido, hetarilo opcionalmente sustituido, arilaquilo opcionalmente sustituido hetarilalquilo opcionalmente sustituido; o R205 y R206 pueden formar junto con el nitrogeno al cual están unidos un anillo de 3 a 7 miembros el cual puede contener adicionalmente uno o más heteroátomos seleccionados entre nitrogeno, oxígeno y azufre; X1 se selecciona entre nitrogeno y C-R212; R211, R212 se seleccionan independientemente entre halogeno, hidrogeno, CN, alquilo C1-3 y NO2; R213 se selecciona entre halogeno, haloalquilo, haloalcoxi, -S(O)kCF3, y ûSF5 o forma un anillo con R214; R214 es hidrogeno o puede constituir junto con R213 un grupo de OCF2O, CF2OCF2, CF2OCF2O y CF2CF2O, el cual forma junto con los carbonos a los cuales están unidos un anillo de cinco a seis miembros; y h, k y n se seleccionan independientemente entre 0,1 y 2; y sus sales aceptables la veterinaria, que se usa para preparar una composicion para el control de parásitos en o sobre un animal; compuestos relacionados; y composicion que los contiene.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16865899P | 1999-12-02 | 1999-12-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR033504A1 true AR033504A1 (es) | 2003-12-26 |
Family
ID=22612402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000106403A AR033504A1 (es) | 1999-12-02 | 2000-12-04 | Uso de 1-arilpirazoles para preparar una composicion para el control de parasitos en o sobre un animal; compuestos relacionados; y composicion que los contiene |
Country Status (20)
Country | Link |
---|---|
US (4) | US6569886B2 (es) |
EP (1) | EP1237873B1 (es) |
JP (1) | JP2003516941A (es) |
KR (1) | KR100816914B1 (es) |
CN (2) | CN1402713A (es) |
AR (1) | AR033504A1 (es) |
AU (1) | AU784798B2 (es) |
BR (1) | BR0015945A (es) |
CA (1) | CA2393197C (es) |
CO (1) | CO5261614A1 (es) |
CZ (1) | CZ20021898A3 (es) |
ES (1) | ES2409630T3 (es) |
HU (1) | HUP0300357A3 (es) |
IL (2) | IL149856A0 (es) |
MX (1) | MXPA02005511A (es) |
MY (1) | MY129771A (es) |
PL (1) | PL364874A1 (es) |
TW (1) | TWI290137B (es) |
WO (1) | WO2001040195A2 (es) |
ZA (1) | ZA200204336B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7569516B2 (en) | 2003-12-24 | 2009-08-04 | Bayer Cropscience Ag | Plant growth regulation |
DK1731512T3 (en) | 2004-03-05 | 2015-01-05 | Nissan Chemical Ind Ltd | Isoxazoline-substituted benzamide AND INSTRUMENTS FOR COMBATING HARMFUL ORGANISMS |
US20050234119A1 (en) * | 2004-04-16 | 2005-10-20 | Soll Mark D | Antiparasitical agents and methods for treating, preventing and controlling external parasites in animals |
FR2869905B1 (fr) | 2004-05-10 | 2008-09-05 | Sanofi Synthelabo | Procede de preparation d'ester de l'acide 1,5-diphenylpyrazole carboxylique. |
GB0413970D0 (en) * | 2004-06-22 | 2004-07-28 | Syngenta Participations Ag | Chemical compounds |
UY28617A1 (es) * | 2004-11-12 | 2006-06-30 | Popley Pharma Ltda | Nuevas composiciones |
US7923465B2 (en) | 2005-06-02 | 2011-04-12 | Glenmark Pharmaceuticals S.A. | Cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation |
HUE037127T2 (hu) | 2007-06-27 | 2018-08-28 | Du Pont | Állati károkozó irtására szolgáló eljárás |
ES2605811T3 (es) * | 2008-11-19 | 2017-03-16 | Merial, Inc. | Derivados de 1-arilpirazol diméricos |
CN102271672B (zh) | 2008-11-19 | 2015-02-04 | 梅里亚有限公司 | 用于治疗寄生物感染的包含单独的或与甲脒组合的1-芳基吡唑的组合物 |
UA108641C2 (uk) | 2010-04-02 | 2015-05-25 | Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування | |
JP5743418B2 (ja) * | 2010-04-09 | 2015-07-01 | Oatアグリオ株式会社 | 新規なピラゾール化合物、その製造方法及び有害生物防除剤 |
JP6249568B2 (ja) | 2011-11-17 | 2017-12-20 | メリアル インコーポレイテッド | アリールピラゾールと置換イミダゾールを含む組成物、その使用方法 |
TWI579274B (zh) | 2012-04-20 | 2017-04-21 | 龍馬躍公司 | 製備1-芳基-5-烷基吡唑化合物的改良方法 |
JP5943387B2 (ja) * | 2012-10-25 | 2016-07-05 | 国立大学法人 名古屋工業大学 | 新規トリフロン誘導体及びその製造方法 |
WO2016069983A1 (en) | 2014-10-31 | 2016-05-06 | Merial, Inc. | Parasiticidal composition comprising fipronil |
US10766866B2 (en) | 2017-10-30 | 2020-09-08 | University Of North Texas Health Science Center At Fort Worth | Deterrents for arthropods and marine organisms |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5232940A (en) | 1985-12-20 | 1993-08-03 | Hatton Leslie R | Derivatives of N-phenylpyrazoles |
GB8713768D0 (en) | 1987-06-12 | 1987-07-15 | May & Baker Ltd | Compositions of matter |
DE3617554A1 (de) * | 1986-05-24 | 1987-11-26 | Bayer Ag | 5-oxy(thio)-pyrazol-derivate |
DE3625686A1 (de) | 1986-07-30 | 1988-02-04 | Bayer Ag | 4-cyano(nitro)-5-oxy(thio)-pyrazol-derivate |
CA2004776C (fr) | 1988-12-13 | 2000-04-25 | Claude Wakselman | Procede de preparation de perfluoroalkylthioethers |
US5079370A (en) | 1989-03-02 | 1992-01-07 | Rhone-Poulenc Ag Company | 1-arylpyrazoles |
US4918085A (en) * | 1989-03-02 | 1990-04-17 | Rhone-Poulenc Ag Company | Pesticidal 3-cyano-5-alkoxy-1-arylpyrazoles, compositions and use |
DE4023488A1 (de) | 1990-07-24 | 1992-01-30 | Bayer Ag | 1-(pyri(mi)dyl-(2)) -5-hydroxy-pyrazol-mikrobizide |
GB9306184D0 (en) | 1993-03-25 | 1993-05-19 | Zeneca Ltd | Heteroaromatic compounds |
GB9601128D0 (en) | 1995-08-11 | 1996-03-20 | Pfizer Ltd | Parasiticidal compounds |
FR2739255B1 (fr) * | 1995-09-29 | 1998-09-04 | Rhone Merieux | Composition antiparasitaire pour le traitement et la protection des animaux de compagnie |
BR9707473A (pt) | 1996-01-30 | 1999-07-27 | Takeda Chemical Industries Ltd | Composto uso e processo para produção do mesmo e composição agroquímica |
GB9625045D0 (en) | 1996-11-30 | 1997-01-22 | Pfizer Ltd | Parasiticidal compounds |
DE19650197A1 (de) | 1996-12-04 | 1998-06-10 | Bayer Ag | 3-Thiocarbamoylpyrazol-Derivate |
TW524667B (en) | 1996-12-05 | 2003-03-21 | Pfizer | Parasiticidal pyrazoles |
NZ336418A (en) | 1996-12-24 | 2001-06-29 | Rhone Poulenc Agrochimie | Pesticidal 3-acetyl-1-aryl-pyrazole derivatives useful for the control of insects, nematodes or helminths |
US6350771B1 (en) | 1996-12-24 | 2002-02-26 | Rhone-Poulenc, Inc. | Pesticidal 1-arylpyrazoles |
CA2275634A1 (en) | 1996-12-24 | 1998-07-02 | Rhone-Poulenc Agrochimie | Pesticidal 1-aryl and pyridylpyrazole derivatives |
JPH11246555A (ja) * | 1997-10-31 | 1999-09-14 | Sumitomo Chem Co Ltd | フッ素置換ベンゾヘテロ環化合物 |
JP2000169453A (ja) * | 1998-09-30 | 2000-06-20 | Mitsubishi Chemicals Corp | 1―フェニルピラゾ―ル―3―カルボキサミド誘導体、その中間体およびこれを有効成分とする農薬 |
-
2000
- 2000-12-01 BR BR0015945-0A patent/BR0015945A/pt not_active Application Discontinuation
- 2000-12-01 MY MYPI20005663A patent/MY129771A/en unknown
- 2000-12-01 AU AU28393/01A patent/AU784798B2/en not_active Expired
- 2000-12-01 WO PCT/EP2000/012100 patent/WO2001040195A2/en not_active Application Discontinuation
- 2000-12-01 PL PL00364874A patent/PL364874A1/xx not_active IP Right Cessation
- 2000-12-01 CN CN00816524A patent/CN1402713A/zh active Pending
- 2000-12-01 CN CNA2006101356663A patent/CN1939909A/zh active Pending
- 2000-12-01 EP EP00993256A patent/EP1237873B1/en not_active Expired - Lifetime
- 2000-12-01 HU HU0300357A patent/HUP0300357A3/hu unknown
- 2000-12-01 CA CA002393197A patent/CA2393197C/en not_active Expired - Lifetime
- 2000-12-01 CZ CZ20021898A patent/CZ20021898A3/cs unknown
- 2000-12-01 CO CO00091998A patent/CO5261614A1/es not_active Application Discontinuation
- 2000-12-01 ES ES00993256T patent/ES2409630T3/es not_active Expired - Lifetime
- 2000-12-01 MX MXPA02005511A patent/MXPA02005511A/es active IP Right Grant
- 2000-12-01 JP JP2001541880A patent/JP2003516941A/ja active Pending
- 2000-12-01 KR KR1020027006979A patent/KR100816914B1/ko not_active IP Right Cessation
- 2000-12-01 IL IL14985600A patent/IL149856A0/xx active IP Right Grant
- 2000-12-02 TW TW089125709A patent/TWI290137B/zh not_active IP Right Cessation
- 2000-12-04 AR ARP000106403A patent/AR033504A1/es unknown
- 2000-12-04 US US09/727,684 patent/US6569886B2/en not_active Expired - Lifetime
-
2002
- 2002-05-26 IL IL149856A patent/IL149856A/en unknown
- 2002-05-30 ZA ZA200204336A patent/ZA200204336B/xx unknown
-
2003
- 2003-04-04 US US10/406,491 patent/US6992099B2/en not_active Expired - Lifetime
-
2005
- 2005-09-27 US US11/235,087 patent/US20060020013A1/en not_active Abandoned
-
2006
- 2006-09-29 US US11/529,778 patent/US7468381B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
HUP0300357A3 (en) | 2009-01-28 |
CA2393197A1 (en) | 2001-06-07 |
US20020111352A1 (en) | 2002-08-15 |
US20030176466A1 (en) | 2003-09-18 |
IL149856A0 (en) | 2002-11-10 |
AU784798B2 (en) | 2006-06-22 |
US6569886B2 (en) | 2003-05-27 |
US6992099B2 (en) | 2006-01-31 |
KR100816914B1 (ko) | 2008-03-26 |
PL364874A1 (en) | 2004-12-27 |
US20070078127A1 (en) | 2007-04-05 |
MXPA02005511A (es) | 2004-09-10 |
WO2001040195A2 (en) | 2001-06-07 |
US20060020013A1 (en) | 2006-01-26 |
AU2839301A (en) | 2001-06-12 |
EP1237873B1 (en) | 2013-04-03 |
TWI290137B (en) | 2007-11-21 |
CZ20021898A3 (cs) | 2003-04-16 |
KR20030016204A (ko) | 2003-02-26 |
EP1237873A2 (en) | 2002-09-11 |
ZA200204336B (en) | 2003-03-20 |
IL149856A (en) | 2009-02-11 |
US7468381B2 (en) | 2008-12-23 |
CA2393197C (en) | 2009-03-03 |
CN1402713A (zh) | 2003-03-12 |
CN1939909A (zh) | 2007-04-04 |
ES2409630T3 (es) | 2013-06-27 |
MY129771A (en) | 2007-04-30 |
CO5261614A1 (es) | 2003-03-31 |
HUP0300357A2 (hu) | 2003-07-28 |
WO2001040195A3 (en) | 2001-11-08 |
JP2003516941A (ja) | 2003-05-20 |
BR0015945A (pt) | 2002-11-12 |
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