AR030021A1 - COMPUESTO DE UNA PIRIMIDINONAS SUSTITUIDA,COMPOSICIoN FARMACÉUTICA QUE LO COMPRENDE Y EL USO DE DICHO COMPUESTO Y DE DICHA COMPOSICIoN EN LA FABRICACIoN DE MEDICAMENTOS uTILES PARA LA INHIBICION SELECTIVA DE LA CASCADA DE COAGULACIoN - Google Patents
COMPUESTO DE UNA PIRIMIDINONAS SUSTITUIDA,COMPOSICIoN FARMACÉUTICA QUE LO COMPRENDE Y EL USO DE DICHO COMPUESTO Y DE DICHA COMPOSICIoN EN LA FABRICACIoN DE MEDICAMENTOS uTILES PARA LA INHIBICION SELECTIVA DE LA CASCADA DE COAGULACIoNInfo
- Publication number
- AR030021A1 AR030021A1 ARP000102446A ARP000102446A AR030021A1 AR 030021 A1 AR030021 A1 AR 030021A1 AR P000102446 A ARP000102446 A AR P000102446A AR P000102446 A ARP000102446 A AR P000102446A AR 030021 A1 AR030021 A1 AR 030021A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- manufacture
- coagulation cascade
- compound
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13479499P | 1999-05-19 | 1999-05-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR030021A1 true AR030021A1 (es) | 2003-08-13 |
Family
ID=22465042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000102446A AR030021A1 (es) | 1999-05-19 | 2000-05-19 | COMPUESTO DE UNA PIRIMIDINONAS SUSTITUIDA,COMPOSICIoN FARMACÉUTICA QUE LO COMPRENDE Y EL USO DE DICHO COMPUESTO Y DE DICHA COMPOSICIoN EN LA FABRICACIoN DE MEDICAMENTOS uTILES PARA LA INHIBICION SELECTIVA DE LA CASCADA DE COAGULACIoN |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP1178970A1 (fr) |
JP (1) | JP2002544262A (fr) |
KR (1) | KR20010114271A (fr) |
CN (1) | CN1157380C (fr) |
AR (1) | AR030021A1 (fr) |
AU (2) | AU771718B2 (fr) |
BR (1) | BR0010758A (fr) |
CA (1) | CA2373614A1 (fr) |
CZ (1) | CZ20014116A3 (fr) |
EA (1) | EA004867B1 (fr) |
HU (1) | HUP0201242A3 (fr) |
IL (1) | IL146243A0 (fr) |
MX (1) | MXPA01011804A (fr) |
NO (1) | NO20015604L (fr) |
NZ (1) | NZ514874A (fr) |
PE (1) | PE20010229A1 (fr) |
PL (1) | PL352827A1 (fr) |
SK (1) | SK15852001A3 (fr) |
TW (1) | TWI222445B (fr) |
UY (1) | UY26156A1 (fr) |
WO (1) | WO2000069832A1 (fr) |
ZA (2) | ZA200109339B (fr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6458952B1 (en) | 1999-05-19 | 2002-10-01 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade |
US6664255B1 (en) | 1999-05-19 | 2003-12-16 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade |
US6716838B1 (en) | 1999-05-19 | 2004-04-06 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents |
US6653316B1 (en) | 1999-05-19 | 2003-11-25 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
US6867217B1 (en) | 1999-05-19 | 2005-03-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade |
CN1152023C (zh) * | 1999-05-19 | 2004-06-02 | 法玛西雅公司 | 作为抗凝血剂的取代的多环芳基与杂芳基尿嘧啶 |
US6750342B1 (en) | 1999-05-19 | 2004-06-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
US7015230B1 (en) | 1999-05-19 | 2006-03-21 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade |
WO2001068605A1 (fr) | 2000-03-13 | 2001-09-20 | Pharmacia Corporation | Benzenes polycycliques substitues aryle et heteroaryle utiles pour l'inhibition selective de la cascade de coagulation |
CA2405306A1 (fr) | 2000-04-05 | 2001-10-18 | Pharmacia Corporation | Pyridones polycycliques 4-aryl et heteroaryl substituees utiles pour l'inhibition selective de la cascade de coagulation |
WO2001077097A2 (fr) | 2000-04-05 | 2001-10-18 | Pharmacia Corporation | 4-pyrones polycycliques a substitution aryle et heteroaryle utiles pour l'inhibition selective de la cascade de coagulation |
US20040171616A9 (en) | 2000-04-17 | 2004-09-02 | South Michael S. | Polycyclic aryl and heteroaryl substituted 1,4-quinones useful for selective inhibition of the coagulation cascade |
AU2001222501A1 (en) * | 2000-05-18 | 2001-11-26 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
US6710058B2 (en) | 2000-11-06 | 2004-03-23 | Bristol-Myers Squibb Pharma Company | Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors |
US7119094B1 (en) | 2000-11-20 | 2006-10-10 | Warner-Lambert Company | Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade |
CA2430037A1 (fr) | 2000-11-20 | 2002-05-30 | Michael S. South | Aryl-et-heteroaryl-pyridines polycycliques substituees utiles dans l'inhibition selective de la cascade de la coagulation |
US7015223B1 (en) | 2000-11-20 | 2006-03-21 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl 1,2,4-triazinones useful for selective inhibition of the coagulation cascade |
BR0213099A (pt) | 2001-10-03 | 2004-10-19 | Pharmacia Corp | Compostos policìclicos de 5 membros substituìdos úteis para inibição seletiva da cascata de coagulação |
CA2462647A1 (fr) * | 2001-10-03 | 2003-04-10 | Michael S. South | Composes heterocycliques insatures a 6 chainons utiles pour l'inhibition selective de reactions en cascade de la coagulation |
CA2462305A1 (fr) | 2001-10-03 | 2003-04-10 | Michael S. South | Composes heterocycliques a 6 chainons utiles dans l'inhibition selective de la cascade de la coagulation |
MXPA04007026A (es) * | 2002-02-22 | 2004-10-11 | Pharmacia & Up John Company | Pirimidinonas y pirimidintionas sustituidas. |
TW200307667A (en) | 2002-05-06 | 2003-12-16 | Bristol Myers Squibb Co | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors |
WO2004103270A2 (fr) | 2003-04-02 | 2004-12-02 | Suntory Pharmaceutical Research Laboratories Llc | Composes et procedes destines au traitement de la thrombose |
US7182738B2 (en) | 2003-04-23 | 2007-02-27 | Marctec, Llc | Patient monitoring apparatus and method for orthosis and other devices |
US8350043B2 (en) * | 2005-06-07 | 2013-01-08 | Pharmacopeia, Inc. | Azinone and diazinone V3 inhibitors for depression and stress disorders |
CN104311537B (zh) * | 2014-09-19 | 2016-08-24 | 广东东阳光药业有限公司 | 含有嘧啶酮乙酰基取代基吡唑类化合物及其组合物及用途 |
CN115779953B (zh) * | 2022-12-19 | 2024-06-21 | 中南大学 | 铜负载碳基单原子材料及其制备方法和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5441960A (en) * | 1992-04-16 | 1995-08-15 | Zeneca Limited | 1-pyrimidinylacetamide human leukocyte elastate inhibitors |
US5948785A (en) * | 1995-04-27 | 1999-09-07 | The Green Cross Corporation | Heterocyclic amide compounds and pharmaceutical use of the same |
-
2000
- 2000-05-17 CA CA002373614A patent/CA2373614A1/fr not_active Abandoned
- 2000-05-17 BR BR0010758-1A patent/BR0010758A/pt not_active IP Right Cessation
- 2000-05-17 JP JP2000618249A patent/JP2002544262A/ja active Pending
- 2000-05-17 HU HU0201242A patent/HUP0201242A3/hu unknown
- 2000-05-17 IL IL14624300A patent/IL146243A0/xx unknown
- 2000-05-17 PL PL00352827A patent/PL352827A1/xx not_active Application Discontinuation
- 2000-05-17 CZ CZ20014116A patent/CZ20014116A3/cs unknown
- 2000-05-17 EP EP00931928A patent/EP1178970A1/fr not_active Withdrawn
- 2000-05-17 SK SK1585-2001A patent/SK15852001A3/sk unknown
- 2000-05-17 NZ NZ514874A patent/NZ514874A/en unknown
- 2000-05-17 CN CNB008077479A patent/CN1157380C/zh not_active Expired - Fee Related
- 2000-05-17 AU AU49734/00A patent/AU771718B2/en not_active Ceased
- 2000-05-17 EA EA200101214A patent/EA004867B1/ru not_active IP Right Cessation
- 2000-05-17 MX MXPA01011804A patent/MXPA01011804A/es unknown
- 2000-05-17 WO PCT/US2000/009806 patent/WO2000069832A1/fr not_active Application Discontinuation
- 2000-05-17 KR KR1020017014753A patent/KR20010114271A/ko not_active Application Discontinuation
- 2000-05-19 UY UY26156A patent/UY26156A1/es not_active Application Discontinuation
- 2000-05-19 AR ARP000102446A patent/AR030021A1/es unknown
- 2000-06-09 PE PE2000000575A patent/PE20010229A1/es not_active Application Discontinuation
- 2000-07-25 TW TW089109595A patent/TWI222445B/zh not_active IP Right Cessation
-
2001
- 2001-11-13 ZA ZA200109339A patent/ZA200109339B/xx unknown
- 2001-11-16 NO NO20015604A patent/NO20015604L/no not_active Application Discontinuation
-
2004
- 2004-01-21 ZA ZA200400448A patent/ZA200400448B/xx unknown
- 2004-05-31 AU AU2004202375A patent/AU2004202375A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU4973400A (en) | 2000-12-05 |
CN1351593A (zh) | 2002-05-29 |
MXPA01011804A (es) | 2003-09-04 |
EA200101214A1 (ru) | 2002-06-27 |
CZ20014116A3 (cs) | 2002-06-12 |
HUP0201242A2 (hu) | 2002-12-28 |
NZ514874A (en) | 2004-11-26 |
ZA200400448B (en) | 2004-09-29 |
ZA200109339B (en) | 2004-05-26 |
CA2373614A1 (fr) | 2000-11-23 |
EA004867B1 (ru) | 2004-08-26 |
AU771718B2 (en) | 2004-04-01 |
EP1178970A1 (fr) | 2002-02-13 |
HUP0201242A3 (en) | 2003-02-28 |
NO20015604L (no) | 2002-01-11 |
SK15852001A3 (sk) | 2003-06-03 |
IL146243A0 (en) | 2002-07-25 |
CN1157380C (zh) | 2004-07-14 |
AU2004202375A1 (en) | 2004-06-24 |
NO20015604D0 (no) | 2001-11-16 |
PL352827A1 (en) | 2003-09-08 |
BR0010758A (pt) | 2003-06-10 |
PE20010229A1 (es) | 2001-03-07 |
KR20010114271A (ko) | 2001-12-31 |
WO2000069832A1 (fr) | 2000-11-23 |
UY26156A1 (es) | 2000-12-29 |
TWI222445B (en) | 2004-10-21 |
JP2002544262A (ja) | 2002-12-24 |
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Legal Events
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