AR029168A1 - Una composicion acidos nucleicos peptidicos y un metodo para prepararla - Google Patents
Una composicion acidos nucleicos peptidicos y un metodo para prepararlaInfo
- Publication number
- AR029168A1 AR029168A1 ARP000103191A ARP000103191A AR029168A1 AR 029168 A1 AR029168 A1 AR 029168A1 AR P000103191 A ARP000103191 A AR P000103191A AR P000103191 A ARP000103191 A AR P000103191A AR 029168 A1 AR029168 A1 AR 029168A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- mixture
- solution
- water
- casein
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- 108091003079 Bovine Serum Albumin Proteins 0.000 abstract 2
- 239000001888 Peptone Substances 0.000 abstract 2
- 108010080698 Peptones Proteins 0.000 abstract 2
- 108020005089 Plant RNA Proteins 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 2
- 229940098773 bovine serum albumin Drugs 0.000 abstract 2
- 239000005018 casein Substances 0.000 abstract 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 2
- 235000021240 caseins Nutrition 0.000 abstract 2
- 235000019319 peptone Nutrition 0.000 abstract 2
- 235000018102 proteins Nutrition 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 108091093037 Peptide nucleic acid Proteins 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 238000009828 non-uniform distribution Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/011—Hydrolysed proteins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/017—Hydrolysed proteins; Derivatives thereof from animals from blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Botany (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Una composicion ácidos nucleicos peptídicos que absorbe luz a longitudes de onda de 230 nm, 260 nm, y 280 nm, de tal modo que resulta en una relacion de absorcion de 260nm/280nm de aproximadamente 1,998 y en una relacion de absorcion de 260nm/230nm de aproximadamente 1,359, comprende moléculas de nucleotidos que resultan de un ARN vegetal y péptidos que resultan de una mezcla de caseína, peptona vacuna y albumina de suero bovino, donde dichas moléculas tienen pesos moleculares con distribucion no uniforme. La composicion es util en el tratamiento de infecciones virales y en la estimulacion del sistema inmunologico. Un método para preparar una composicion comprende los pasos de; a) formar una mezcla que incluye una combinacion de proteínas que consiste en caseína, peptona vacuna y albumina de suero bovino; un ARN vegetal; y una base en agua, donde la relacion en peso de dicha combinacion de proteínas a dicho agua está en el rango de aproximadamente 1,5:100 a aproximadamente 2,5:100 por peso; b) procesar dicha mezcla a una temperatura elevada y a una presion elevada para formar una solucion y elementos insolubles; c) remover dichos elementos insolubles; d) diluir dicha solucion con agua; y e) luego de realizar los pasos b, c, y d, ajustar el pH de dicha solucion a un valor de pH aceptable desde el punto de vista fisiologico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/344,095 US6303153B1 (en) | 1996-10-22 | 1999-06-25 | Preparation of a therapeutic composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR029168A1 true AR029168A1 (es) | 2003-06-18 |
Family
ID=23349031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000103191A AR029168A1 (es) | 1999-06-25 | 2000-06-23 | Una composicion acidos nucleicos peptidicos y un metodo para prepararla |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6303153B1 (es) |
| EP (1) | EP1206313A4 (es) |
| CN (1) | CN1199716C (es) |
| AR (1) | AR029168A1 (es) |
| AU (1) | AU5765700A (es) |
| CA (1) | CA2376931A1 (es) |
| IL (1) | IL147496A0 (es) |
| MX (1) | MXPA02000190A (es) |
| WO (1) | WO2001000306A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6878269B2 (en) * | 1996-01-31 | 2005-04-12 | Kaneka Corporation | Device for body fluid purification and system for body fluid purification |
| US6528098B2 (en) * | 1996-10-22 | 2003-03-04 | Advanced Viral Research Corp. | Preparation of a therapeutic composition |
| EP0975216A4 (en) * | 1997-04-15 | 2002-05-02 | Advanced Viral Res Corp | METHOD OF TREATING PAPILLOMA VIRUS INFECTIONS |
| US7439234B2 (en) * | 1997-04-15 | 2008-10-21 | Advanced Viral Research Corporation | Method for treating cancer patients undergoing chemotherapy |
| US20010049351A1 (en) * | 1999-02-25 | 2001-12-06 | Shalom Z. Hirschman | Method of determining down-regulation of the expression of hiv coreceptor, ccr5 with product r |
| US20040033244A1 (en) * | 2002-05-28 | 2004-02-19 | Advanced Viral Research, Corp. | Treatment of cancers of lymphocytic cells with product R |
| US7324705B2 (en) * | 2003-11-06 | 2008-01-29 | Compudigm International Limited | Image distortion system and method |
| CA2578212A1 (en) * | 2004-08-27 | 2006-03-09 | Advanced Viral Research Corp. | Methods for promoting wound healing |
| ES2391278T3 (es) | 2005-06-03 | 2012-11-23 | Ohr Pharmaceutical, Inc. | Métodos para proporcionar cuidado paliativo con Producto R |
| US20090311236A1 (en) * | 2008-06-11 | 2009-12-17 | Immune @Work, Inc. | Therapeutic Peptide Compositions And Methods Of Making And Using Same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5849196A (en) * | 1996-10-07 | 1998-12-15 | Immune Modulation Maximum | Composition containing peptides and nucleic acids and methods of making same |
| WO1998046241A1 (en) * | 1997-04-15 | 1998-10-22 | Advanced Viral Research Corp. | A combination therapy for hiv infections |
| US5902786A (en) * | 1997-04-15 | 1999-05-11 | Advanced Viral Research Corp. | Treatment of basal cell carcinoma with product R, a peptide-nucleic acid preparation |
| US5807839A (en) * | 1997-04-15 | 1998-09-15 | Advanced Viral Research Corp. | Method for stimulating red blood cell production |
| US5807840A (en) * | 1997-11-04 | 1998-09-15 | Advanced Viral Research Corp. | Method for treating canine distemper |
-
1999
- 1999-06-25 US US09/344,095 patent/US6303153B1/en not_active Expired - Lifetime
-
2000
- 2000-06-23 EP EP00943141A patent/EP1206313A4/en not_active Ceased
- 2000-06-23 AU AU57657/00A patent/AU5765700A/en not_active Abandoned
- 2000-06-23 AR ARP000103191A patent/AR029168A1/es unknown
- 2000-06-23 WO PCT/US2000/017447 patent/WO2001000306A1/en active Application Filing
- 2000-06-23 IL IL14749600A patent/IL147496A0/xx unknown
- 2000-06-23 MX MXPA02000190A patent/MXPA02000190A/es active IP Right Grant
- 2000-06-23 CN CNB008114935A patent/CN1199716C/zh not_active Expired - Fee Related
- 2000-06-23 CA CA002376931A patent/CA2376931A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU5765700A (en) | 2001-01-31 |
| US6303153B1 (en) | 2001-10-16 |
| WO2001000306A9 (en) | 2002-06-06 |
| CA2376931A1 (en) | 2001-01-04 |
| EP1206313A4 (en) | 2006-04-19 |
| CN1199716C (zh) | 2005-05-04 |
| CN1368899A (zh) | 2002-09-11 |
| EP1206313A1 (en) | 2002-05-22 |
| IL147496A0 (en) | 2002-08-14 |
| MXPA02000190A (es) | 2003-05-23 |
| WO2001000306A1 (en) | 2001-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |