AR025990A1 - Uso de derivados de carbonilamino para el tratamiento de enfermedades relacionadas con el sistema. - Google Patents
Uso de derivados de carbonilamino para el tratamiento de enfermedades relacionadas con el sistema.Info
- Publication number
- AR025990A1 AR025990A1 ARP000105311A ARP000105311A AR025990A1 AR 025990 A1 AR025990 A1 AR 025990A1 AR P000105311 A ARP000105311 A AR P000105311A AR P000105311 A ARP000105311 A AR P000105311A AR 025990 A1 AR025990 A1 AR 025990A1
- Authority
- AR
- Argentina
- Prior art keywords
- treatment
- derivatives
- carbonilamine
- diseases related
- lower alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Addiction (AREA)
- AIDS & HIV (AREA)
- Vascular Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Uso de derivados de carbonilamino de formula general 1 donde R significa alquilo inferior, alquenilo inferior, alquinilo inferior, cicloalquilo, alcoxiinferior o CF3; R1 significa hidrogeno o alquilo inferior; R2 y R3 significan, independientemente uno del otro, hidrogneo, halogeno o nitro; Y significa CH oN; n es 0-6; m es 0-2; como así también sus sales farmacéuticamente aceptables, para el tratamiento de enfermedades, relacionado con antagonistas y/o agonistasdel receptor de glutamato metabotropico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99120327 | 1999-10-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR025990A1 true AR025990A1 (es) | 2002-12-26 |
Family
ID=8239189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000105311A AR025990A1 (es) | 1999-10-12 | 2000-10-09 | Uso de derivados de carbonilamino para el tratamiento de enfermedades relacionadas con el sistema. |
Country Status (18)
Country | Link |
---|---|
US (1) | US6548522B1 (es) |
EP (1) | EP1224163B1 (es) |
JP (1) | JP4098523B2 (es) |
KR (1) | KR100468253B1 (es) |
CN (1) | CN1184964C (es) |
AR (1) | AR025990A1 (es) |
AT (1) | ATE292107T1 (es) |
AU (1) | AU775656B2 (es) |
BR (1) | BR0014712A (es) |
CA (1) | CA2388470C (es) |
DE (1) | DE60019145T2 (es) |
DK (1) | DK1224163T3 (es) |
ES (1) | ES2238316T3 (es) |
MX (1) | MXPA02003673A (es) |
PT (1) | PT1224163E (es) |
TR (1) | TR200200969T2 (es) |
WO (1) | WO2001027070A1 (es) |
ZA (1) | ZA200202437B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6399641B1 (en) * | 2000-07-13 | 2002-06-04 | Hoffmann-La Roche Inc. | 2H-tetrazole-amide compounds with therapeutic activity as metabotropic glutamate receptor agonists |
WO2003004010A1 (en) * | 2001-07-06 | 2003-01-16 | Poseidon Pharmaceuticals A/S | Carbonylamino derivatives useful for obtaining immune regulation |
WO2003059873A1 (en) | 2002-01-04 | 2003-07-24 | Poseidon Pharmaceuticals A/S | Potassium channel modulators |
NZ582934A (en) | 2007-08-02 | 2011-10-28 | Recordati Ireland Ltd | Novel heterocyclic compounds as mglu5 antagonists |
JP2010536827A (ja) | 2007-08-24 | 2010-12-02 | ノイロサーチ アクティーゼルスカブ | ある種の炎症性障害の治療に有用なカルボニルアミノ誘導体 |
EP2393780A1 (en) | 2009-02-04 | 2011-12-14 | Recordati Ireland Limited | Heterocyclic derivatives as m-glu5 antagonists |
WO2011029633A1 (en) | 2009-09-14 | 2011-03-17 | Recordati Ireland Limited | Heterocyclic mglu5 antagonists |
CN101786982A (zh) * | 2010-03-30 | 2010-07-28 | 华东师范大学 | 一种合成2-吡啶基苯乙腈的方法 |
KR101862626B1 (ko) * | 2010-07-09 | 2018-05-31 | 레코르다티 아일랜드 리미티드 | Mglu5 대항체로서의 신 스피로헤테로사이클릭 화합물 |
BR112013015072A2 (pt) | 2010-12-17 | 2016-07-12 | Rhodes Technologies | síntese de cloridrato de metilfenidato à baixa temperatura |
CN110372530B (zh) * | 2019-08-06 | 2021-07-30 | 郑州大学 | 一种含α取代苯基结构的化合物及其制备方法和消杀剂 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL129434C (es) | 1966-03-12 | |||
EP0474589A1 (de) | 1990-08-02 | 1992-03-11 | Ciba-Geigy Ag | Orthophenolacetamide |
US6071970A (en) | 1993-02-08 | 2000-06-06 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
JP3197822B2 (ja) | 1996-01-31 | 2001-08-13 | 株式会社スリオンテック | 可逆性感熱記録組成物とそれを用いた書き替え可能な可逆性感熱記録シートおよびカード |
WO1997046511A1 (en) | 1996-06-07 | 1997-12-11 | Nps Pharmaceuticals, Inc. | Coumpounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
DE69832302D1 (de) | 1997-12-10 | 2005-12-15 | Nps Pharma Inc | Antikonvulsive und zns-aktive bis-fluoralkylamide |
-
2000
- 2000-09-26 US US09/669,583 patent/US6548522B1/en not_active Expired - Fee Related
- 2000-10-06 MX MXPA02003673A patent/MXPA02003673A/es active IP Right Grant
- 2000-10-06 CA CA002388470A patent/CA2388470C/en not_active Expired - Fee Related
- 2000-10-06 PT PT00969435T patent/PT1224163E/pt unknown
- 2000-10-06 AT AT00969435T patent/ATE292107T1/de not_active IP Right Cessation
- 2000-10-06 AU AU79151/00A patent/AU775656B2/en not_active Ceased
- 2000-10-06 KR KR10-2002-7004679A patent/KR100468253B1/ko not_active IP Right Cessation
- 2000-10-06 WO PCT/EP2000/009781 patent/WO2001027070A1/en active IP Right Grant
- 2000-10-06 ES ES00969435T patent/ES2238316T3/es not_active Expired - Lifetime
- 2000-10-06 DE DE60019145T patent/DE60019145T2/de not_active Expired - Fee Related
- 2000-10-06 JP JP2001530091A patent/JP4098523B2/ja not_active Expired - Fee Related
- 2000-10-06 EP EP00969435A patent/EP1224163B1/en not_active Expired - Lifetime
- 2000-10-06 BR BR0014712-5A patent/BR0014712A/pt not_active Application Discontinuation
- 2000-10-06 CN CNB008141142A patent/CN1184964C/zh not_active Expired - Fee Related
- 2000-10-06 TR TR2002/00969T patent/TR200200969T2/xx unknown
- 2000-10-06 DK DK00969435T patent/DK1224163T3/da active
- 2000-10-09 AR ARP000105311A patent/AR025990A1/es not_active Application Discontinuation
-
2002
- 2002-03-26 ZA ZA200202437A patent/ZA200202437B/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE60019145D1 (de) | 2005-05-04 |
CA2388470A1 (en) | 2001-04-19 |
EP1224163B1 (en) | 2005-03-30 |
AU775656B2 (en) | 2004-08-12 |
ATE292107T1 (de) | 2005-04-15 |
DK1224163T3 (da) | 2005-06-27 |
CN1378528A (zh) | 2002-11-06 |
DE60019145T2 (de) | 2006-01-26 |
EP1224163A1 (en) | 2002-07-24 |
US6548522B1 (en) | 2003-04-15 |
ES2238316T3 (es) | 2005-09-01 |
CA2388470C (en) | 2008-08-05 |
CN1184964C (zh) | 2005-01-19 |
KR20020038947A (ko) | 2002-05-24 |
AU7915100A (en) | 2001-04-23 |
BR0014712A (pt) | 2002-06-18 |
PT1224163E (pt) | 2005-06-30 |
MXPA02003673A (es) | 2002-08-30 |
KR100468253B1 (ko) | 2005-01-27 |
ZA200202437B (en) | 2003-09-23 |
TR200200969T2 (tr) | 2002-07-22 |
WO2001027070A1 (en) | 2001-04-19 |
JP4098523B2 (ja) | 2008-06-11 |
JP2003511436A (ja) | 2003-03-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR057906A1 (es) | Derivados de pirimidona biciclicos sustituidos y su uso en la preparacion de medicamentos para el tratamiento de enfermedades mediadas por la actividad anormal de gsk3beta. | |
SV2002000197A (es) | Nuevos derivados de biarileter utiles como inhibidores de la recaptacion de monoaminas ref. pc10602/20073/bb | |
CL2004000655A1 (es) | Compuestos derivados de piperidin-2-ona 1,6-disustituidos, sus sales, composicion farmaceutica, agonistas del receptor ep4; uso de los compuestos para tratar hipertension ocular, glaucoma. | |
CR7643A (es) | Derivados de 1-heterociclialquil -3-sulfonilazaindol o azaindazol como ligandos de 5-hidroxitriptamina-6 | |
ECSP055536A (es) | Derivados de 1-heterociclilalquil-3-sulfonilindol o indazol como ligandos de 5-hidroxitriptamina-6 | |
SV2002000022A (es) | Inhibidores de recanalizacion de la monoamida para el tratamiento de los desordenes del sistema nervioso central ref. pc10434 | |
DOP2006000076A (es) | Derivados de ciclopentapiridina y tetrahidroquinolina | |
AR025990A1 (es) | Uso de derivados de carbonilamino para el tratamiento de enfermedades relacionadas con el sistema. | |
ECSP055636A (es) | Acidos tienil-hidroxamicos sustituidos, y su uso para tratar enfermedades asociadas con la actividad enzimatica de la histona desacetilasa | |
AR058807A1 (es) | 5-(fenilisoxazoletoxi)-triazol-3-il piridinas sustituidas, para el tratamiento de trastornos mediados por el receptor mglur5 | |
ECSP045473A (es) | Derivados de 1-(aminoalquil)-3-sulfonilindol y 1-aminoalquil-3-sulfonilindazol como ligandos de 5-hidroxitriptamina-6 | |
ECSP034640A (es) | Derivados de feniletenilo o feniletinilo como antagonistas del receptor del glutamato | |
AR066659A1 (es) | Derivados de espiroindolinona | |
AR032361A1 (es) | Derivados de androstano y sales y solvatos de los mismos, su uso para la fabricacion de medicamentos, composiciones farmaceuticas que comprenden tales compuestos, proceso para la preparacion de dichos compuestos, e intermediarios utiles en la preparacion de tales compuestos | |
UY27370A1 (es) | Derivados de benzamida tiazol y composiciones farmacéuticas para inhibir la proliferación de células y métodos para su utilización | |
CR9459A (es) | Derivados benzodioxano y benzodioxolano y usos de los mismos | |
AR115694A1 (es) | Degradadores selectivos del receptor de estrógeno | |
AR053712A1 (es) | Heteroarilos sustituidos, antagonistas de cb1 (receptor 1 canabinoide) | |
AR007118A1 (es) | 4(3h)-quinazolinonas 2,3 disustituidas y composiciones farmaceuticas que las contienen | |
CR8270A (es) | Derivados de tetrazol y metodos para el tratamiento con los mismos de trastornos relacionados con el metabolismo | |
ECSP088584A (es) | Nuevos derivados de benzimidazol como inhibidores del receptor vanilloide 1 (vrl) | |
AR029400A1 (es) | Derivados de isoxazolcarboxamida, un metodo para su preparacion y una composicion farmaceutica que los comprende | |
PE20060632A1 (es) | Derivados de arilsulfonilestilbeno como antagonistas de los receptores 5-ht2a | |
AR066604A1 (es) | Derivados de arilamida pirimidona, medicamentos que los contienen y usos terapeuticos para prevenir y/o tratar enfermedades neurodegenerativas fundamentalmente. | |
ECSP045156A (es) | Derivados de indolilalquilamina como ligandos 5-hidroxitriptamina-6 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |