AR020978A2 - UN PROCESO PARA MEDIR LA CONCENTRACION EN UNA MUESTRA ACUOSA DE UN ANALITO SUJETO A OXIDACIoN PARA UNA ENZIMA DEPENDIENTE DE NAD. - Google Patents

UN PROCESO PARA MEDIR LA CONCENTRACION EN UNA MUESTRA ACUOSA DE UN ANALITO SUJETO A OXIDACIoN PARA UNA ENZIMA DEPENDIENTE DE NAD.

Info

Publication number
AR020978A2
AR020978A2 ARP990105401A ARP990105401A AR020978A2 AR 020978 A2 AR020978 A2 AR 020978A2 AR P990105401 A ARP990105401 A AR P990105401A AR P990105401 A ARP990105401 A AR P990105401A AR 020978 A2 AR020978 A2 AR 020978A2
Authority
AR
Argentina
Prior art keywords
nad
dependent enzyme
analyte
oxidation
compound
Prior art date
Application number
ARP990105401A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of AR020978A2 publication Critical patent/AR020978A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Electrochemistry (AREA)
  • Emergency Medicine (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Un proceso para medir la concentracion de una muestra acuosa de un analito sujeto a oxidacion por una enzima dependiente de NAD que consiste en: a) oxidarel analito con una enzima dependiente de NAD(P)+ en presencia de NAD(P)+; b) oxidar la NAD(P)Hg enerada por la reaccion con el analito y la enzima dependientedel NAD(P)+ con un compuesto mediador que tiene una de las dos formulas (1) y (2) donde X e Y pueden ser independientemente oxígeno, azufre, CR3R4, NR3 o elgrupo funcional NR3R4 o elgrupo funcional, CZ1Z2, donde Z1 y Z2 son grupos extractores de electrones; R1 y R2 pueden ser independientemente aromáticos oheteroaromáticos sustituidos o no sustituidos; y R3 y R4 pueden ser independientemente hidrogeno, alquilo, arilo,heteroarilo sus tituido o no sustituido oamino, oxhidrilo, alcoxilo o ariloxilo; y c) aplicar un potencial eléctrico en un electrodo para reoxidar el compuesto mediador reducido al oxidar NAD(P)H yobservar la corriente resultante, donde parte delcompuesto mediador se reduce mediante la reaccion con NAD(P)H en tanto que otra parte del compuesto mediadorse está oxidando por la transferencia de electrones a dicho electrodo durante un período de medicion y la velocidad de oxidacion delcompuesto mediador en elcurs o de dicho período de medicion y, en consecuencia, la corriente resultante observada está monotonicamente relacionada con la concentracion del analito enla muestra.
ARP990105401A 1997-10-16 1999-10-26 UN PROCESO PARA MEDIR LA CONCENTRACION EN UNA MUESTRA ACUOSA DE UN ANALITO SUJETO A OXIDACIoN PARA UNA ENZIMA DEPENDIENTE DE NAD. AR020978A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6198297P 1997-10-16 1997-10-16

Publications (1)

Publication Number Publication Date
AR020978A2 true AR020978A2 (es) 2002-06-05

Family

ID=22039479

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP980105170A AR019002A1 (es) 1997-10-16 1998-10-16 UNA TIRA DESECHABLE DE ELECTRODOS PARA CONECTAR A UN CIRCUITO DE LECTURA DE SENAL DE UNA DISPOSICIoN DE SENSORES PARA DETECTAR UNA CORRIENTE REPRESENTATIVA DE UN ANALITO EN UNA MUESTRA ACUOSA, Y PROCEDIMIENTO PARA MEDIR LA CONCENTRACIoN DE UN ANALITO CON DICHA TIRA.
ARP990105401A AR020978A2 (es) 1997-10-16 1999-10-26 UN PROCESO PARA MEDIR LA CONCENTRACION EN UNA MUESTRA ACUOSA DE UN ANALITO SUJETO A OXIDACIoN PARA UNA ENZIMA DEPENDIENTE DE NAD.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP980105170A AR019002A1 (es) 1997-10-16 1998-10-16 UNA TIRA DESECHABLE DE ELECTRODOS PARA CONECTAR A UN CIRCUITO DE LECTURA DE SENAL DE UNA DISPOSICIoN DE SENSORES PARA DETECTAR UNA CORRIENTE REPRESENTATIVA DE UN ANALITO EN UNA MUESTRA ACUOSA, Y PROCEDIMIENTO PARA MEDIR LA CONCENTRACIoN DE UN ANALITO CON DICHA TIRA.

Country Status (13)

Country Link
EP (3) EP1023455B1 (es)
JP (1) JP4373604B2 (es)
AR (2) AR019002A1 (es)
AT (1) ATE361373T1 (es)
AU (1) AU743468C (es)
BR (1) BR9814086A (es)
CA (2) CA2667767C (es)
CO (1) CO5040209A1 (es)
DE (2) DE69837712T2 (es)
ES (2) ES2285787T3 (es)
HK (1) HK1106798A1 (es)
TW (1) TW584723B (es)
WO (1) WO1999019507A1 (es)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6241862B1 (en) * 1996-02-14 2001-06-05 Inverness Medical Technology, Inc. Disposable test strips with integrated reagent/blood separation layer
US7112265B1 (en) 1996-02-14 2006-09-26 Lifescan Scotland Limited Disposable test strips with integrated reagent/blood separation layer
US20050103624A1 (en) * 1999-10-04 2005-05-19 Bhullar Raghbir S. Biosensor and method of making
US6541216B1 (en) 1999-12-22 2003-04-01 Roche Diagnostics Corporation Amperometric biosensor test strip
US6716577B1 (en) * 2000-02-02 2004-04-06 Lifescan, Inc. Electrochemical test strip for use in analyte determination
DE10032042A1 (de) * 2000-07-05 2002-01-24 Inventus Biotec Gesellschaft Fuer Innovative Bioanalytik, Biosensoren Und Diagnostika Mbh & Co. Kg Elektrochemischer Einwegbiosensor für die quantitative Bestimmung von Analytkonzentrationen in Flüssigkeiten
US6726818B2 (en) * 2000-07-21 2004-04-27 I-Sens, Inc. Biosensors with porous chromatographic membranes
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP1279742A1 (en) * 2001-07-23 2003-01-29 Applied NanoSystems B.V. Method of binding a compound to a sensor surface using hydrophobin
US6863800B2 (en) * 2002-02-01 2005-03-08 Abbott Laboratories Electrochemical biosensor strip for analysis of liquid samples
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7198606B2 (en) 2002-04-19 2007-04-03 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with analyte sensing
US6743635B2 (en) 2002-04-25 2004-06-01 Home Diagnostics, Inc. System and methods for blood glucose sensing
DE10243569A1 (de) * 2002-09-19 2004-04-01 Infineon Technologies Ag Schaltkreis-Anordnung und Verfahren zum Herstellen einer Schaltkreis-Anordnung
US7501053B2 (en) 2002-10-23 2009-03-10 Abbott Laboratories Biosensor having improved hematocrit and oxygen biases
US20040118704A1 (en) 2002-12-19 2004-06-24 Yi Wang Analyte test intrument having improved versatility
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
AU2002368515A1 (en) * 2002-12-31 2004-07-22 Council Of Scientific And Industrial Research Process for preparation of enzyme electrode
AU2002368512A1 (en) * 2002-12-31 2004-07-22 Council Of Scientific And Industrial Research Method for preparing lactate biosensing strip
WO2004058993A1 (en) * 2002-12-31 2004-07-15 Council Of Scientific And Industrial Research Lactate biosensing strip
US7267837B2 (en) 2003-01-16 2007-09-11 Arun Kumar Enzyme electrode and process for preparation thereof
US7311812B2 (en) 2003-05-30 2007-12-25 Abbott Laboratories Biosensor
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
EP1671096A4 (en) 2003-09-29 2009-09-16 Pelikan Technologies Inc METHOD AND APPARATUS FOR PROVIDING IMPROVED SAMPLE CAPTURING DEVICE
US20050067277A1 (en) * 2003-09-30 2005-03-31 Pierce Robin D. Low volume electrochemical biosensor
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
WO2005065414A2 (en) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Method and apparatus for improving fluidic flow and sample capture
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
WO2005121759A2 (en) * 2004-05-24 2005-12-22 Albatros Technologies Gmbh & Co. Kg Device and method for analyte measurement
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc METHOD AND APPARATUS FOR MANUFACTURING A DEVICE FOR SAMPLING LIQUIDS
US8784624B2 (en) * 2006-07-12 2014-07-22 Arkray, Inc. Enzyme electrode
ES2307400B1 (es) * 2006-10-03 2009-09-30 Consejo Superior De Investigaciones Cientificas Sensor optico de glucosa basado en la deposicion de la enzima gdh (glucosa deshidrogenasa) y su coenzima nad+ (nicotinamida adenina dinucleotico) en un soporte de fibra optica estrechada.
EP1964927A1 (de) * 2007-02-27 2008-09-03 F. Hoffmann-La Roche AG Chinone als Mediatoren für photometrische Teste
KR20080080841A (ko) * 2007-03-02 2008-09-05 주식회사 아이센스 전기화학적 바이오센서 및 이의 측정기
US8008037B2 (en) 2008-03-27 2011-08-30 Roche Diagnostics Operations, Inc. Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
DE102009028553B4 (de) * 2008-11-24 2019-10-31 Comde Computer Meßtechnik Design und Entwicklungs GmbH Messelement für die Staubmessung, Vorrichtung zur Herstellung mindestens eines Messelements für die Staubmessung und Lagerungsvorrichtung für mindestens ein Messelement für die Staubmessung
WO2010070719A1 (ja) * 2008-12-15 2010-06-24 株式会社札幌イムノ・ダイアグノスティック・ラボラトリー バイオセンサおよび基質濃度の測定方法
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US20100326824A1 (en) * 2009-06-24 2010-12-30 Lifescan, Inc. Analyte test strip with combination electrode contact and meter identification feature
CN102498391B (zh) 2009-08-31 2014-03-19 松下电器产业株式会社 传感器及浓度测定方法
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9594044B2 (en) * 2010-09-30 2017-03-14 Panasonic Healthcare Holdings Co., Ltd. Reagent composition, sensor, sensor system, and sensor manufacture process
JP6205545B2 (ja) * 2012-06-25 2017-10-04 合同会社バイオエンジニアリング研究所 酵素電極
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
US8921061B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
WO2014152717A2 (en) 2013-03-14 2014-09-25 Sano Intelligence, Inc. On-body microsensor for biomonitoring
US10820860B2 (en) 2013-03-14 2020-11-03 One Drop Biosensor Technologies, Llc On-body microsensor for biomonitoring
US20150257687A1 (en) 2014-03-13 2015-09-17 Sano Intelligence, Inc. System for monitoring body chemistry
US10595754B2 (en) 2014-03-13 2020-03-24 Sano Intelligence, Inc. System for monitoring body chemistry
ES2685978T3 (es) * 2014-03-13 2018-10-15 PAL Finland Oy Tira reactiva y aparato para medir el contenido de alcohol en sangre, y un método para medir el contenido de alcohol en sangre
GB201412136D0 (en) 2014-07-08 2014-08-20 Univ Bristol Sensor
US10655160B2 (en) 2015-08-31 2020-05-19 Regents Of The University Of Minnesota Formaldehyde graphene sensor
USD824034S1 (en) 2016-12-15 2018-07-24 Sano Intelligence, Inc. Biomonitoring interface device
USD820988S1 (en) 2017-01-20 2018-06-19 Sano Intelligence, Inc. Biomonitoring sensor system for monitoring body chemistry
US12076145B2 (en) 2018-04-19 2024-09-03 Abbott Diabetes Care Inc. Lactate sensors and associated methods
US11821022B2 (en) * 2019-12-23 2023-11-21 Medtronic Minimed, Inc. Ethylene oxide absorption layer for analyte sensing and method
TW202203850A (zh) 2020-03-13 2022-02-01 瑞士商赫孚孟拉羅股份公司 製備工作電極的方法
CN112378973B (zh) * 2020-10-21 2023-12-22 清华-伯克利深圳学院筹备办公室 电子元器件的生产方法、传感器的制备方法和应用
USD988882S1 (en) 2021-04-21 2023-06-13 Informed Data Systems Inc. Sensor assembly

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1218704A (en) 1983-05-05 1987-03-03 Graham Davis Assay systems using more than one enzyme
GB8608435D0 (en) * 1986-04-07 1986-05-14 Cranfield Inst Of Tech Specific binding assays
GB8817421D0 (en) 1988-07-21 1988-08-24 Medisense Inc Bioelectrochemical electrodes
US5212622A (en) * 1989-11-03 1993-05-18 Specialized Conductives Pty. Ltd. Large surface area electrodes
JP3370414B2 (ja) * 1994-01-24 2003-01-27 松下電器産業株式会社 バイオセンサの製造方法
US5628890A (en) * 1995-09-27 1997-05-13 Medisense, Inc. Electrochemical sensor
US6214612B1 (en) * 1996-03-07 2001-04-10 Matsushita Electric Industrial Co., Ltd. Cholesterol sensor containing electrodes, cholesterol dehydrogenase, nicotinamide adenine dinucleotide and oxidized electron mediator
EP1801229B1 (en) 1997-10-16 2010-09-01 Abbott Laboratories Biosensor electrode

Also Published As

Publication number Publication date
BR9814086A (pt) 2000-10-03
AU743468B2 (en) 2002-01-24
TW584723B (en) 2004-04-21
ATE361373T1 (de) 2007-05-15
CA2667767C (en) 2013-04-09
CA2305800A1 (en) 1999-04-22
AR019002A1 (es) 2001-12-26
HK1106798A1 (en) 2008-03-20
ES2349059T3 (es) 2010-12-22
CO5040209A1 (es) 2001-05-29
EP2298928A3 (en) 2011-06-29
CA2305800C (en) 2011-05-24
CA2667767A1 (en) 1999-04-22
EP1023455A1 (en) 2000-08-02
EP1023455B1 (en) 2007-05-02
EP2119795A1 (en) 2009-11-18
DE69837712T2 (de) 2008-01-10
AU1090999A (en) 1999-05-03
EP2119795B1 (en) 2012-05-23
JP4373604B2 (ja) 2009-11-25
AU743468C (en) 2002-11-07
DE69841877D1 (de) 2010-10-14
JP2001520367A (ja) 2001-10-30
WO1999019507A1 (en) 1999-04-22
DE69837712D1 (de) 2007-06-14
ES2285787T3 (es) 2007-11-16
EP2298928A2 (en) 2011-03-23

Similar Documents

Publication Publication Date Title
AR020978A2 (es) UN PROCESO PARA MEDIR LA CONCENTRACION EN UNA MUESTRA ACUOSA DE UN ANALITO SUJETO A OXIDACIoN PARA UNA ENZIMA DEPENDIENTE DE NAD.
Moiroux et al. Mechanistic aspects of the electrochemical oxidation of dihydronicotinamide adenine dinucleotide (NADH)
US5498542A (en) Electrode mediators for regeneration of NADH and NADPH
US5356786A (en) Interferant eliminating biosensor
RU2007141387A (ru) Окисляемые виды соединений в качестве внутреннего стандарта в контрольных растворах для биосенсоров
ATE124990T1 (de) Redox-vermittlungs-reagenz und biosensor.
EP2623974B1 (en) Sensor, sensor system, and sensor manufacture process
EP0390390A1 (en) Electrochemical biosensor based on immobilized enzymes and redox polymers
Bianco et al. Current—potential responses for a tetrahemic protein: a method of determining the individual half-wave potentials of cytochrome c3 from Desulfovibrio desulfuricans strain Norway
Gülce et al. Amperometric enzyme electrode for aerobic glucose monitoring prepared by glucose oxidase immobilized in poly (vinylferrocenium)
JPH1144667A (ja) バイオセンサ
EP0230786B1 (en) Assay for cholesterol and derivatives thereof
Wang et al. Plant tissue-based amperometric electrode for eliminating ascorbic acid interferences
Mizutani et al. Amperometric glucose-sensing electrode based on carbon paste containing poly (ethylene glycol)-modified glucose oxidase and cobalt octaethoxyphthalocyanine
Connor et al. Silicone-grease-based immobilisation method for the preparation of enzyme electrodes
Hale et al. Investigation of viologen derivatives as electron-transfer mediators in amperometric glucose sensors
Arai et al. Xanthine and hypoxanthine sensors based on xanthine oxidase immobilized in poly (mercapto-p-benzoquinone) film
Arai et al. Pyruvate sensor based on pyruvate oxidase immobilized in a poly (mercapto-p-benzoquinone) film
Hale et al. Glutamate biosensors based on electrical communication between L-glutamate oxidase and a flexible redox polymer
JPH02253566A (ja) グルコース生物電池及びグルコースセンサー
Zahir et al. Fabrication of directly polymerized 4-vinylpyridine onto a pencil 2B graphite paste electrode for glucose monitoring
Wang et al. Critical comparison of metallized and mediator‐based carbon paste glucose biosensors
FI954968A0 (fi) Peroksidaasia ja kolloidista kultaa sisältäviä oksidaasibiosensoreita ilman välittäjää tapahtuvaan glukoosin määritykseen
Shul'ga et al. An alternative microbiosensor for hydrogen peroxide based on an enzyme field effect transistor with a fast response
Villar et al. Determination of mitoxantrone by flow injection analysis using an amperometric detector

Legal Events

Date Code Title Description
FG Grant, registration