AR018180A1 - Procedimiento para la preparacion de acidos hidroxamicos - Google Patents

Procedimiento para la preparacion de acidos hidroxamicos

Info

Publication number
AR018180A1
AR018180A1 ARP990101598A ARP990101598A AR018180A1 AR 018180 A1 AR018180 A1 AR 018180A1 AR P990101598 A ARP990101598 A AR P990101598A AR P990101598 A ARP990101598 A AR P990101598A AR 018180 A1 AR018180 A1 AR 018180A1
Authority
AR
Argentina
Prior art keywords
aryl
heteroaryl
alkyl
alkoxy
oxaryl
Prior art date
Application number
ARP990101598A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR018180A1 publication Critical patent/AR018180A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08Hydroxylamino compounds or their ethers or esters
    • C07C239/14Hydroxylamino compounds or their ethers or esters having nitrogen atoms of hydroxylamino groups further bound to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Abstract

Compuestos de la formula (I), pueden así prepararse, donde: Z es > CH2 o >NR1; Q es alquilo C1-6, arilo C6-10. heteroarilo C2-9, oxiarilo C6-10 alquiloC1-6, oxiarilo C6-10 arilo C6-10, oxiarilo C6-10 heteroarilo C2-9, arilo C6-10 alquilo C1-6, aril C6-10 arilo C6-10, aril C6-10 heteroarilo C2-9, aril C6-10aril C6-10 alquilo C1-6, aril C6-10 aril C6-10 arilo C1-10, aril C6-10 aril C6-10 heteroarilo C2-9, heteroaril C2-9 alquilo C1-6, heteroaril C2-9 arilo C6-10,heteroarilo C2-9heteroarilo C2-9, arilo C6-10 alcoxi C1-6 alquilo C1-6, arilo C6-10 alcoxi C1-6 arilo C6-10, aril C6-10 alcoxi C1-6 heteroarilo C2-9, oxiheteroarilo C2-9 alquilo C1-6, oxiheteroarilo C2-9 arilo C6-10, oxiheteroarilo C2-9 heteroarilo C2-9, heteroaril C2-9 alcoxi C1-6 alquilo C1-6, heteroaril C2-9alcoxi C1-6 arilo C6-10 o heteroaril C2-9 alcoxi C1-6 heteroarilo C2-9; en la que cada radical arilo C6-10 o heteroarilo C2-9 de dichos arilo C6-10,heteroarilo C2-9, oxiarilo C6-10, alquilo C1-6, oxiarilo C6-10, arilo C6-10, oxiarilo C6-10 heteroarilo C2-9, arilo C6-10 alquilo C1-6, arilC6-10 arilo C6-10, aril C6-10 heteroarilo C2-9, aril C6-10 aril C6-10 alquilo C1-6, aril C6-10 aril C6-10 arilo C6-10, aril C6-10 aril C6-10 heteroarilo C2-9,heteroaril C2-9 alquilo C1-6, heteroaril C2-9 arilo C6-10, heteroarilo C2-9 heteroarilo C2-9, arilo C6-10 alcoxi C1-6 alquilo C1-6, arilo C6-10 alcoxiC1-6 arilo C6-10, arilo C6-10 alcoxi C1-6 heteroarilo C2-9, oxiheteroarilo C2-9 alquilo C1-6, oxiheteroarilo C2-9 arilo C6-10,oxiheteroarilo C2-9 heteroariloC2-9, heteroaril C2-9 alcoxi C1-6 alquilo C1-6, heteroaril C2-9 alcoxi C1-6 arilo C6-10 o heteroaril C2-9 alcoxi C1-6 heteroarilo C2-9 estáopcionalmente sustituido sobre cualquiera de los átoMs de carbono del anillo capaces de formar un enlace adicional mediante uno o más sustituyentespor anillo independientemente seleccionado entre fluoro, cloro, bromo, alquilo C1-6, alcoxi C1-6, perfluoro alquilo C1-3, perfluoro alcoxi C1-3 y oxiariloC6-10; R1 es hidrogeno, alquilo C1-6, aril C6-10 alquilo C1-6, heteroaril C2-9 alquilo C1-6 o un grupo de formula (II), en la que R1 y R3 son
ARP990101598A 1998-04-10 1999-04-08 Procedimiento para la preparacion de acidos hidroxamicos AR018180A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8136598P 1998-04-10 1998-04-10

Publications (1)

Publication Number Publication Date
AR018180A1 true AR018180A1 (es) 2001-10-31

Family

ID=22163686

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990101598A AR018180A1 (es) 1998-04-10 1999-04-08 Procedimiento para la preparacion de acidos hidroxamicos

Country Status (38)

Country Link
US (1) US6288246B1 (es)
EP (1) EP0949244A3 (es)
JP (1) JPH11343277A (es)
KR (1) KR100329902B1 (es)
CN (1) CN1232023A (es)
AP (1) AP1203A (es)
AR (1) AR018180A1 (es)
AU (1) AU747629B2 (es)
BG (1) BG64154B1 (es)
BR (1) BR9901089A (es)
CA (1) CA2268680A1 (es)
CO (1) CO5070713A1 (es)
DZ (1) DZ2757A1 (es)
EA (1) EA002777B1 (es)
EG (1) EG22263A (es)
GT (1) GT199900046A (es)
HR (1) HRP990105A2 (es)
HU (1) HUP9901041A3 (es)
ID (1) ID23337A (es)
IL (1) IL129328A0 (es)
IN (1) IN192342B (es)
IS (1) IS5019A (es)
MA (1) MA24831A1 (es)
NO (1) NO991672L (es)
NZ (1) NZ335104A (es)
OA (1) OA11031A (es)
PA (1) PA8469301A1 (es)
PE (1) PE20000418A1 (es)
PL (1) PL332450A1 (es)
SG (1) SG125880A1 (es)
SK (1) SK43699A3 (es)
TN (1) TNSN99052A1 (es)
TR (1) TR199900755A2 (es)
TW (1) TW448147B (es)
UA (1) UA57750C2 (es)
UY (1) UY25460A1 (es)
YU (1) YU18199A (es)
ZA (1) ZA992631B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9918684D0 (en) 1999-08-09 1999-10-13 Novartis Ag Organic compounds
US6458822B2 (en) 2000-03-13 2002-10-01 Pfizer Inc. 2-oxo-imidazolidine-4-carboxylic acid hydroxamide compounds that inhibit matrix metalloproteinases
GB0103303D0 (en) 2001-02-09 2001-03-28 Novartis Ag Organic compounds
WO2004106319A1 (en) * 2003-05-30 2004-12-09 Pfizer Products Inc. Crystal forms of 4-[4-(4-fluorophenoxy)benzenesulfonylamino]-tetrahydropyran-4-carboxylic acid hydroxyamide
AU2003264355A1 (en) * 2003-08-29 2005-03-29 Basf Aktiengesellschaft Process for production of o-substituted hydroxylamines
CA2933174A1 (en) 2013-12-18 2015-06-25 Brita Lp Filter assembly for filter as you pour filtration
TW202237119A (zh) 2020-12-10 2022-10-01 美商住友製藥腫瘤公司 Alk﹘5抑制劑和彼之用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA794723B (en) 1978-09-11 1980-08-27 Univ Miami Anti-hypertensive agents
GB9000725D0 (en) 1990-01-12 1990-03-14 Pfizer Ltd Therapeutic agents
US5552419A (en) * 1993-01-06 1996-09-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
US5863949A (en) 1995-03-08 1999-01-26 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
KR20000068248A (ko) 1996-08-23 2000-11-25 디. 제이. 우드, 스피겔 알렌 제이 아릴설포닐아미노 하이드록삼산 유도체
US6303636B1 (en) 1997-02-03 2001-10-16 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
CA2299355C (en) 1997-08-08 2005-09-27 Pfizer Products Inc. Aryloxyarylsulfonylamino hydroxamic acid derivatives
PT895988E (pt) 1997-08-08 2002-09-30 Pfizer Prod Inc Derivados do acido arilsulfonilamino-hidroxamico
PA8469401A1 (es) 1998-04-10 2000-05-24 Pfizer Prod Inc Derivados biciclicos del acido hidroxamico

Also Published As

Publication number Publication date
KR19990083051A (ko) 1999-11-25
AU747629B2 (en) 2002-05-16
BR9901089A (pt) 2000-05-30
AP9901503A0 (en) 1999-06-30
IL129328A0 (en) 2000-02-17
EP0949244A2 (en) 1999-10-13
UA57750C2 (uk) 2003-07-15
HUP9901041A3 (en) 2003-02-28
EG22263A (en) 2002-11-30
PA8469301A1 (es) 2000-09-29
AU2369099A (en) 1999-10-21
TW448147B (en) 2001-08-01
KR100329902B1 (ko) 2002-03-22
SG125880A1 (en) 2006-10-30
EA002777B1 (ru) 2002-08-29
OA11031A (en) 2002-02-07
TNSN99052A1 (fr) 2005-11-10
EP0949244A3 (en) 2001-05-30
CO5070713A1 (es) 2001-08-28
YU18199A (sh) 2002-11-15
US6288246B1 (en) 2001-09-11
NZ335104A (en) 2000-10-27
BG64154B1 (bg) 2004-02-27
TR199900755A3 (tr) 1999-11-22
ID23337A (id) 2000-04-05
MA24831A1 (fr) 1999-12-31
PE20000418A1 (es) 2000-05-23
GT199900046A (es) 2000-09-15
CN1232023A (zh) 1999-10-20
BG103319A (en) 2001-08-31
NO991672L (no) 1999-10-11
HUP9901041A2 (hu) 2000-03-28
EA199900284A2 (ru) 1999-10-28
UY25460A1 (es) 1999-11-17
NO991672D0 (no) 1999-04-09
AP1203A (en) 2003-09-05
PL332450A1 (en) 1999-10-11
JPH11343277A (ja) 1999-12-14
EA199900284A3 (ru) 2000-04-24
ZA992631B (en) 2000-10-09
SK43699A3 (en) 2000-06-12
DZ2757A1 (fr) 2003-09-15
IN192342B (es) 2004-04-10
IS5019A (is) 1999-10-11
TR199900755A2 (xx) 1999-11-22
HU9901041D0 (en) 1999-06-28
HRP990105A2 (en) 2000-02-29
CA2268680A1 (en) 1999-10-10

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