AR016175A1 - Compuestos derivados del acido dihidroxihexanoico, su uso para la preparacion de medicamentos y composiciones de los mismos. - Google Patents
Compuestos derivados del acido dihidroxihexanoico, su uso para la preparacion de medicamentos y composiciones de los mismos.Info
- Publication number
- AR016175A1 AR016175A1 ARP990100443A ARP990100443A AR016175A1 AR 016175 A1 AR016175 A1 AR 016175A1 AR P990100443 A ARP990100443 A AR P990100443A AR P990100443 A ARP990100443 A AR P990100443A AR 016175 A1 AR016175 A1 AR 016175A1
- Authority
- AR
- Argentina
- Prior art keywords
- octyl
- amide
- methyl
- carboxylic acid
- dihydroxy
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- UPUZGXILYFKSGE-UHFFFAOYSA-N quinoxaline-2-carboxylic acid Chemical compound C1=CC=CC2=NC(C(=O)O)=CN=C21 UPUZGXILYFKSGE-UHFFFAOYSA-N 0.000 abstract 6
- 125000006509 3,4-difluorobenzyl group Chemical group [H]C1=C(F)C(F)=C([H])C(=C1[H])C([H])([H])* 0.000 abstract 2
- AMKQPUGRVXSJNI-UHFFFAOYSA-N 7,8-difluoroquinoline-3-carboxylic acid Chemical compound FC1=C(F)C=CC2=CC(C(=O)O)=CN=C21 AMKQPUGRVXSJNI-UHFFFAOYSA-N 0.000 abstract 2
- 125000004847 2-fluorobenzyl group Chemical group [H]C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000003852 3-chlorobenzyl group Chemical group [H]C1=C([H])C(=C([H])C(Cl)=C1[H])C([H])([H])* 0.000 abstract 1
- 125000006284 3-fluorobenzyl group Chemical group [H]C1=C([H])C(=C([H])C(F)=C1[H])C([H])([H])* 0.000 abstract 1
- UTACWMGSNKJDEE-UHFFFAOYSA-N 6,7,8-trifluoroquinoline-3-carboxylic acid Chemical compound FC1=C(F)C(F)=CC2=CC(C(=O)O)=CN=C21 UTACWMGSNKJDEE-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- AIDS & HIV (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7380198P | 1998-02-05 | 1998-02-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR016175A1 true AR016175A1 (es) | 2001-06-20 |
Family
ID=22115885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990100443A AR016175A1 (es) | 1998-02-05 | 1999-02-03 | Compuestos derivados del acido dihidroxihexanoico, su uso para la preparacion de medicamentos y composiciones de los mismos. |
Country Status (36)
| Country | Link |
|---|---|
| EP (1) | EP1051405B1 (,) |
| JP (1) | JP3693916B2 (,) |
| KR (1) | KR100385529B1 (,) |
| CN (1) | CN1177834C (,) |
| AP (1) | AP992A (,) |
| AR (1) | AR016175A1 (,) |
| AT (1) | ATE337307T1 (,) |
| AU (1) | AU752407B2 (,) |
| BG (1) | BG104726A (,) |
| BR (1) | BR9907655A (,) |
| CA (1) | CA2320388C (,) |
| DE (1) | DE69932920T2 (,) |
| DZ (1) | DZ2717A1 (,) |
| EA (1) | EA003137B1 (,) |
| ES (1) | ES2268847T3 (,) |
| GT (1) | GT199900011A (,) |
| HR (1) | HRP20000529B1 (,) |
| HU (1) | HUP0100832A3 (,) |
| IL (1) | IL137330A0 (,) |
| IS (1) | IS5562A (,) |
| MA (1) | MA26603A1 (,) |
| MY (1) | MY133125A (,) |
| NO (1) | NO20003965D0 (,) |
| NZ (1) | NZ505724A (,) |
| OA (1) | OA11448A (,) |
| PA (1) | PA8467301A1 (,) |
| PE (1) | PE20000243A1 (,) |
| PL (1) | PL342817A1 (,) |
| SK (1) | SK11262000A3 (,) |
| TN (1) | TNSN99013A1 (,) |
| TR (1) | TR200002248T2 (,) |
| TW (1) | TW470744B (,) |
| UA (1) | UA57824C2 (,) |
| WO (1) | WO1999040061A2 (,) |
| YU (1) | YU47100A (,) |
| ZA (1) | ZA99873B (,) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2360672A1 (en) * | 1999-01-29 | 2000-08-03 | Wayne W. Hancock | Methods for preventing graft rejection and ischemia-reperfusion injury |
| CA2376275A1 (en) * | 1999-08-20 | 2001-03-01 | Michael John Ricks | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation |
| HRP20020638A2 (en) * | 2000-02-04 | 2004-12-31 | Pfizer Prod Inc | Heterocyclic amide derivatives |
| EP1498417A1 (en) * | 2000-02-04 | 2005-01-19 | Pfizer Products Inc. | Heterocyclic amide derivatives |
| US6740636B2 (en) * | 2000-07-31 | 2004-05-25 | Schering Aktiengesellschaft | Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection |
| US6746856B2 (en) | 2000-08-09 | 2004-06-08 | Pfizer Inc. | Microbial conversion of bicyclic heteroaromatic compounds |
| BR0210518A (pt) * | 2001-06-22 | 2004-06-22 | Pfizer Prod Inc | Composições farmacêuticas de dispersões de drogas e polìmeros neutros |
| EP1269994A3 (en) * | 2001-06-22 | 2003-02-12 | Pfizer Products Inc. | Pharmaceutical compositions comprising drug and concentration-enhancing polymers |
| HUP0400281A3 (en) | 2001-06-22 | 2009-11-30 | Pfizer Prod Inc | Pharmaceutical compositions of adsorbates of amorphous drug and process for their preparation |
| DE10152351B4 (de) * | 2001-10-18 | 2005-09-22 | Schering Ag | Feste Arzneimittelformulierung für ein Piperazinharnstoffderivat |
| JP2005523262A (ja) | 2002-02-01 | 2005-08-04 | ファイザー・プロダクツ・インク | 薬物及び親油性ミクロ相形成物質の非晶質分散物の医薬組成物 |
| WO2003095440A1 (en) * | 2002-05-14 | 2003-11-20 | Pfizer Products Inc. | Dihydroxyhexanoic acid derivatives, their intermediates, and methods of making |
| MXPA04011231A (es) * | 2002-05-14 | 2005-01-25 | Pfizer Prod Inc | Metodos para fabricar derivados de dihidro-furan-2-ona. |
| JP2005538130A (ja) * | 2002-08-12 | 2005-12-15 | ファイザー・プロダクツ・インク | キノキサリン−２−カルボン酸［４−カルバモイル−１−（３−フルオロベンジル）−２，７−ジヒドロキシ−７−メチル−オクチル］−アミドの結晶形 |
| CN1681479A (zh) | 2002-08-12 | 2005-10-12 | 辉瑞产品公司 | 半有序药物和聚合物的药物组合物 |
| US20040087571A1 (en) * | 2002-10-30 | 2004-05-06 | Pfizer Inc | Methods of using CCR1 antagonists as immunomodulatory agents |
| US20040097554A1 (en) * | 2002-10-30 | 2004-05-20 | Pfizer Inc | Heteroaryl-hexanoic acid amide derivatives as immonomodulatory agents |
| BRPI0413277A (pt) | 2003-08-04 | 2006-10-10 | Pfizer Prod Inc | composições farmacêuticas de adsorvatos de medicamentos amorfos e materiais que formam microfases lipofìlicas |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923864A (en) * | 1987-12-15 | 1990-05-08 | Pfizer Inc. | Certain heterocyclic-hexanamides useful for treating hypertension |
| DE69527405T2 (de) * | 1994-10-19 | 2003-03-13 | Novartis Ag, Basel | Antivirale Ether von Aspartat-Protease-Substrat-Isosteren |
| DE19708106A1 (de) * | 1997-02-28 | 1998-09-03 | Bosch Gmbh Robert | Einrichtung und Verfahren zur Information über Verkehrsstörungen |
-
1999
- 1999-01-18 YU YU47100A patent/YU47100A/sh unknown
- 1999-01-18 UA UA2000074534A patent/UA57824C2/uk unknown
- 1999-01-18 CA CA002320388A patent/CA2320388C/en not_active Expired - Fee Related
- 1999-01-18 BR BR9907655-1A patent/BR9907655A/pt not_active Application Discontinuation
- 1999-01-18 AU AU17789/99A patent/AU752407B2/en not_active Ceased
- 1999-01-18 EA EA200000741A patent/EA003137B1/ru not_active IP Right Cessation
- 1999-01-18 WO PCT/IB1999/000067 patent/WO1999040061A2/en not_active Ceased
- 1999-01-18 HU HU0100832A patent/HUP0100832A3/hu unknown
- 1999-01-18 NZ NZ505724A patent/NZ505724A/xx unknown
- 1999-01-18 HR HR20000529 patent/HRP20000529B1/xx not_active IP Right Cessation
- 1999-01-18 PA PA19998467301A patent/PA8467301A1/es unknown
- 1999-01-18 IL IL13733099A patent/IL137330A0/xx unknown
- 1999-01-18 KR KR10-2000-7008561A patent/KR100385529B1/ko not_active Expired - Fee Related
- 1999-01-18 PL PL99342817A patent/PL342817A1/xx not_active Application Discontinuation
- 1999-01-18 SK SK1126-2000A patent/SK11262000A3/sk unknown
- 1999-01-18 ES ES99900098T patent/ES2268847T3/es not_active Expired - Lifetime
- 1999-01-18 JP JP2000530493A patent/JP3693916B2/ja not_active Expired - Lifetime
- 1999-01-18 CN CNB998027138A patent/CN1177834C/zh not_active Expired - Fee Related
- 1999-01-18 EP EP99900098A patent/EP1051405B1/en not_active Expired - Lifetime
- 1999-01-18 DE DE69932920T patent/DE69932920T2/de not_active Expired - Lifetime
- 1999-01-18 AT AT99900098T patent/ATE337307T1/de not_active IP Right Cessation
- 1999-01-18 TR TR2000/02248T patent/TR200002248T2/xx unknown
- 1999-01-27 GT GT199900011A patent/GT199900011A/es unknown
- 1999-02-01 PE PE1999000071A patent/PE20000243A1/es not_active Application Discontinuation
- 1999-02-01 TW TW088101505A patent/TW470744B/zh not_active IP Right Cessation
- 1999-02-03 MY MYPI99000363A patent/MY133125A/en unknown
- 1999-02-03 TN TNTNSN99013A patent/TNSN99013A1/fr unknown
- 1999-02-03 DZ DZ990018A patent/DZ2717A1/xx active
- 1999-02-03 MA MA25448A patent/MA26603A1/fr unknown
- 1999-02-03 AR ARP990100443A patent/AR016175A1/es unknown
- 1999-02-04 ZA ZA9900873A patent/ZA99873B/xx unknown
- 1999-02-04 AP APAP/P/1999/001457A patent/AP992A/en active
-
2000
- 2000-07-14 IS IS5562A patent/IS5562A/is unknown
- 2000-07-28 OA OA1200000214A patent/OA11448A/en unknown
- 2000-08-04 NO NO20003965A patent/NO20003965D0/no not_active Application Discontinuation
- 2000-08-29 BG BG104726A patent/BG104726A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |