AR016125A1 - Analisis de nucleotidos en solucion utilizando un efecto de reduccion de la intensidad fluorescente - Google Patents
Analisis de nucleotidos en solucion utilizando un efecto de reduccion de la intensidad fluorescenteInfo
- Publication number
- AR016125A1 AR016125A1 ARP980103211A ARP980103211A AR016125A1 AR 016125 A1 AR016125 A1 AR 016125A1 AR P980103211 A ARP980103211 A AR P980103211A AR P980103211 A ARP980103211 A AR P980103211A AR 016125 A1 AR016125 A1 AR 016125A1
- Authority
- AR
- Argentina
- Prior art keywords
- nucleotides
- probes
- analysis
- solution
- reduction effect
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6832—Enhancement of hybridisation reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La invencion brinda un método para secuenciar y analizar mediante ensayo, en forma rápida, economica y efectiva, nucleotidos en un medio líquido,utilizando fluorescencia inducida por láser de sondas antisentido, incluyendo sondas PNA. La intensidadf luorescente del medio resultante es inversamenteproporcional a la eficiencia de hibridizacion de las sondas con respecto a la secuencia blanco. El método es particularmente ventajoso debido a que norequiere la separacion de sondas no hibridizadasy complejos de hibridizacion antes de la deteccion. El método puede utilizarse para identificar regionesaccesibles en secuencia de nucleotidos plegados, para identificar el numero de pares sin coincidencia en un complejo de hibridizacion y paramapearg enomas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/886,280 US5846729A (en) | 1997-02-27 | 1997-07-01 | Assaying nucleotides in solution using a fluorescent intensity quenching effect |
Publications (1)
Publication Number | Publication Date |
---|---|
AR016125A1 true AR016125A1 (es) | 2001-06-20 |
Family
ID=25388774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980103211A AR016125A1 (es) | 1997-07-01 | 1998-07-01 | Analisis de nucleotidos en solucion utilizando un efecto de reduccion de la intensidad fluorescente |
Country Status (10)
Country | Link |
---|---|
US (1) | US5846729A (es) |
EP (1) | EP1002125A1 (es) |
JP (1) | JP2001510681A (es) |
AR (1) | AR016125A1 (es) |
AU (1) | AU730865B2 (es) |
CA (1) | CA2295333C (es) |
IN (1) | IN189178B (es) |
TW (1) | TWI235765B (es) |
WO (1) | WO1999001578A1 (es) |
ZA (1) | ZA985758B (es) |
Families Citing this family (67)
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US6403313B1 (en) * | 1999-12-21 | 2002-06-11 | Ingeneus Corporation | Fluorescent intensity assay for duplex and triplex nucleic acid hybridization solution utilizing fluorescent intercalators |
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US6294333B1 (en) | 1998-12-31 | 2001-09-25 | Ingeneus Corp. | Fluorescent intensity assay for protein or peptide binding to nucleic acids |
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US6656692B2 (en) * | 1999-12-21 | 2003-12-02 | Ingeneus Corporation | Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes |
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US6645733B1 (en) | 1999-06-25 | 2003-11-11 | Ingeneus Corporation | Fluorescent intensity method for assaying binding between proteins or peptides |
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WO2001038585A2 (en) * | 1999-11-24 | 2001-05-31 | The Regents Of The University Of California | Polymer arrays and methods of using labeled probe molecules to identify and quantify target molecule expression |
US7052844B2 (en) * | 1999-12-21 | 2006-05-30 | Ingeneus, Inc. | Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism |
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US7309569B2 (en) * | 1999-12-21 | 2007-12-18 | Ingeneus, Inc. | Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes |
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RU2483049C2 (ru) * | 2011-07-21 | 2013-05-27 | Открытое акционерное общество "Научно-исследовательский институт полимерных материалов" | Способ изготовления партии многошашечных зарядов твердого ракетного топлива |
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CA2190430A1 (en) * | 1995-12-12 | 1997-06-13 | Margret Barbara Basinski | Method for measuring genetic messages |
-
1997
- 1997-07-01 US US08/886,280 patent/US5846729A/en not_active Expired - Lifetime
-
1998
- 1998-06-30 TW TW087110536A patent/TWI235765B/zh not_active IP Right Cessation
- 1998-06-30 AU AU80302/98A patent/AU730865B2/en not_active Ceased
- 1998-06-30 CA CA002295333A patent/CA2295333C/en not_active Expired - Fee Related
- 1998-06-30 EP EP98928474A patent/EP1002125A1/en not_active Withdrawn
- 1998-06-30 IN IN1838DE1998 patent/IN189178B/en unknown
- 1998-06-30 JP JP2000501276A patent/JP2001510681A/ja active Pending
- 1998-06-30 WO PCT/IB1998/001016 patent/WO1999001578A1/en not_active Application Discontinuation
- 1998-07-01 AR ARP980103211A patent/AR016125A1/es active IP Right Grant
- 1998-07-01 ZA ZA985758A patent/ZA985758B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU730865B2 (en) | 2001-03-15 |
ZA985758B (en) | 1999-01-27 |
AU8030298A (en) | 1999-01-25 |
CA2295333C (en) | 2005-03-01 |
JP2001510681A (ja) | 2001-08-07 |
IN189178B (es) | 2003-01-04 |
WO1999001578A1 (en) | 1999-01-14 |
EP1002125A1 (en) | 2000-05-24 |
TWI235765B (en) | 2005-07-11 |
US5846729A (en) | 1998-12-08 |
CA2295333A1 (en) | 1999-01-14 |
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