AR015946A1 - Formulacion farmaceutica que comprende bifosfonatos, proceso para su preparacion, uso de la formulacion para la fabricacion de un medicamento, metodo parala inhibicion de la reabsorcion osea, y metodo para el tratamiento y prevencion de osteoporosis - Google Patents
Formulacion farmaceutica que comprende bifosfonatos, proceso para su preparacion, uso de la formulacion para la fabricacion de un medicamento, metodo parala inhibicion de la reabsorcion osea, y metodo para el tratamiento y prevencion de osteoporosisInfo
- Publication number
- AR015946A1 AR015946A1 ARP980104956A ARP980104956A AR015946A1 AR 015946 A1 AR015946 A1 AR 015946A1 AR P980104956 A ARP980104956 A AR P980104956A AR P980104956 A ARP980104956 A AR P980104956A AR 015946 A1 AR015946 A1 AR 015946A1
- Authority
- AR
- Argentina
- Prior art keywords
- formulation
- osteoporosis
- prevention
- treatment
- reabsortion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Las formulaciones farmacéuticas comprenden por lo menos un bisfosfonato y un agente mejorador de la absorcion que consiste esencialmente de un glicérido decadena medio o una mezcla de glicéridos de cadena media. Dichas formulaciones farmacéuticas sonutiles para la inhibicion de la reabsorcion osea y para eltratamiento y prevencion de la osteoporosis.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9703691A SE9703691D0 (sv) | 1997-10-10 | 1997-10-10 | Pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
AR015946A1 true AR015946A1 (es) | 2001-05-30 |
Family
ID=20408561
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980104956A AR015946A1 (es) | 1997-10-10 | 1998-10-05 | Formulacion farmaceutica que comprende bifosfonatos, proceso para su preparacion, uso de la formulacion para la fabricacion de un medicamento, metodo parala inhibicion de la reabsorcion osea, y metodo para el tratamiento y prevencion de osteoporosis |
Country Status (14)
Country | Link |
---|---|
US (1) | US6372728B1 (es) |
EP (2) | EP1310259A3 (es) |
JP (1) | JP2001519398A (es) |
AR (1) | AR015946A1 (es) |
AT (1) | ATE240107T1 (es) |
AU (1) | AU9469198A (es) |
DE (1) | DE69814656T2 (es) |
DK (1) | DK1021194T3 (es) |
ES (1) | ES2200378T3 (es) |
PT (1) | PT1021194E (es) |
SA (1) | SA98190775A (es) |
SE (1) | SE9703691D0 (es) |
WO (1) | WO1999018972A1 (es) |
ZA (1) | ZA988886B (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2321864A1 (en) * | 1998-12-25 | 2000-07-06 | Toray Industries, Inc. | Interleukin-6 production inhibitor |
US7658938B2 (en) * | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
US20070148228A1 (en) * | 1999-02-22 | 2007-06-28 | Merrion Research I Limited | Solid oral dosage form containing an enhancer |
US8119159B2 (en) * | 1999-02-22 | 2012-02-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
SE9901272D0 (sv) * | 1999-04-09 | 1999-04-09 | Astra Ab | New improved formulation |
RU2288722C2 (ru) * | 2000-06-20 | 2006-12-10 | Новартис Аг | Способ введения бисфосфонатов |
NZ523086A (en) | 2000-06-20 | 2007-07-27 | Novartis Ag | Method of administering bisphosphonates |
US6638920B2 (en) * | 2000-07-21 | 2003-10-28 | Merck & Co., Inc. | Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses |
JP4381805B2 (ja) * | 2001-07-02 | 2009-12-09 | メリオン リサーチ スリー リミテッド | 生物活性材料の送達 |
JP4546704B2 (ja) * | 2002-02-14 | 2010-09-15 | 救急薬品工業株式会社 | 経皮投与製剤 |
KR100998856B1 (ko) | 2002-02-14 | 2010-12-08 | 규큐 야쿠힝 고교 가부시키가이샤 | 경피투여제제 |
KR20120065435A (ko) | 2002-05-10 | 2012-06-20 | 에프. 호프만-라 로슈 아게 | 골다공증 치료 및 예방용 비스포스폰산 |
ITMI20032175A1 (it) * | 2003-11-11 | 2005-05-12 | Tiberio Bruzzese | Formulazioni farmaceutiche di bisfosfonati destinate |
US20050182028A1 (en) * | 2004-02-13 | 2005-08-18 | Chen Chih-Ming J. | Pharmaceutical formulation for oral delivery of bisphosphates |
KR20080083068A (ko) * | 2004-05-24 | 2008-09-12 | 더 프록터 앤드 갬블 캄파니 | 킬레이팅제를 함유하는 비스포스포네이트의 고형의 장용 경구 투여 형태 |
US8012949B2 (en) * | 2004-10-08 | 2011-09-06 | The Board Of Trustees Of The University Of Illinois | Bisphosphonate compounds and methods with enhanced potency for multiple targets including FPPS, GGPPS, and DPPS |
US7358361B2 (en) * | 2004-10-08 | 2008-04-15 | The Board Of Trustees Of The University Of Illinois | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases |
CN101227892B (zh) * | 2005-04-08 | 2013-06-05 | 舌交付有限公司 | 口腔给药系统 |
US7473684B2 (en) * | 2005-09-16 | 2009-01-06 | Selamine Limited | Bisphosphonate formulation |
CA2646334A1 (en) * | 2006-03-17 | 2007-09-27 | The Board Of Trustees Of The University Of Illinois | Bisphosphonate compounds and methods |
MX2008012678A (es) * | 2006-04-07 | 2008-12-17 | Merrion Res Iii Ltd | Forma de dosis oral solida que contiene un mejorador. |
WO2007132714A1 (ja) * | 2006-05-16 | 2007-11-22 | The Nisshin Oillio Group, Ltd. | 骨密度増加剤 |
CA2654566A1 (en) * | 2006-06-09 | 2007-12-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
GB0616794D0 (en) | 2006-08-24 | 2006-10-04 | Arrow Int Ltd | Solid dosage form |
US20080139514A1 (en) * | 2006-11-29 | 2008-06-12 | Subhash Pandurang Gore | Diphosphonic acid pharmaceutical compositions |
GB0624087D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril combination salt |
GB0624090D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amine salts |
GB0624084D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amino acid salts |
US8974801B2 (en) * | 2006-12-21 | 2015-03-10 | Amphastar Pharmaceuticals Inc. | Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate |
KR20110007242A (ko) * | 2008-05-07 | 2011-01-21 | 메리온 리서치 Ⅲ 리미티드 | 펩티드 조성물 및 그의 제조 방법 |
US20100215743A1 (en) * | 2009-02-25 | 2010-08-26 | Leonard Thomas W | Composition and drug delivery of bisphosphonates |
US20110182985A1 (en) * | 2010-01-28 | 2011-07-28 | Coughlan David C | Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof |
US9089484B2 (en) | 2010-03-26 | 2015-07-28 | Merrion Research Iii Limited | Pharmaceutical compositions of selective factor Xa inhibitors for oral administration |
CN103476419A (zh) | 2011-01-07 | 2013-12-25 | 梅里翁第三研究有限公司 | 口服投药的含铁药物组合物 |
ES2975708T3 (es) | 2015-01-29 | 2024-07-12 | Novo Nordisk As | Comprimidos que comprenden agonista del GLP-1 y recubrimiento entérico |
CN105267145B (zh) * | 2015-11-01 | 2019-06-21 | 袁旭东 | 双膦酸盐的自乳化配方和相关剂型 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL175882C (nl) * | 1977-03-28 | Procter & Gamble | Farmaceutisch preparaat, dat een verbinding met ontstekingtegengaande werking bevat. | |
GB8618259D0 (en) * | 1986-07-25 | 1986-09-03 | Leo Pharm Prod Ltd | Pharmaceutical compositions |
MX21452A (es) * | 1989-07-07 | 1994-01-31 | Ciba Geigy Ag | Preparaciones farmaceuticas que se administran en forma topica. |
DE69023844T2 (de) * | 1989-09-06 | 1996-06-20 | Merck & Co Inc | Acyloxymethylester der Bisphonsäuren als Knochenresorptions-Inhibitoren. |
SE9003100D0 (sv) | 1990-09-28 | 1990-09-28 | Kabivitrum Ab | Lipid formulation system |
US5391743A (en) * | 1992-05-29 | 1995-02-21 | Procter & Gamble Pharmaceuticals, Inc. | Quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism and methods of treating and preventing dental calculus and plaque |
EP0684834A4 (en) | 1993-02-17 | 1996-09-25 | Smithkline Beecham Corp | MICROEMULSIONS CONTAINING THERAPEUTIC PEPTIDES. |
JP3411690B2 (ja) * | 1994-09-21 | 2003-06-03 | 帝人株式会社 | 局所投与用アレンドロン酸ナトリウム製剤 |
GB9516268D0 (en) * | 1995-08-08 | 1995-10-11 | Danbiosyst Uk | Compositiion for enhanced uptake of polar drugs from the colon |
-
1997
- 1997-10-10 SE SE9703691A patent/SE9703691D0/xx unknown
-
1998
- 1998-09-29 ZA ZA988886A patent/ZA988886B/xx unknown
- 1998-10-05 ES ES98948029T patent/ES2200378T3/es not_active Expired - Lifetime
- 1998-10-05 AU AU94691/98A patent/AU9469198A/en not_active Abandoned
- 1998-10-05 PT PT98948029T patent/PT1021194E/pt unknown
- 1998-10-05 AT AT98948029T patent/ATE240107T1/de active
- 1998-10-05 US US09/171,950 patent/US6372728B1/en not_active Expired - Fee Related
- 1998-10-05 EP EP03001707A patent/EP1310259A3/en not_active Withdrawn
- 1998-10-05 EP EP98948029A patent/EP1021194B1/en not_active Expired - Lifetime
- 1998-10-05 DE DE69814656T patent/DE69814656T2/de not_active Expired - Lifetime
- 1998-10-05 AR ARP980104956A patent/AR015946A1/es not_active Application Discontinuation
- 1998-10-05 DK DK98948029T patent/DK1021194T3/da active
- 1998-10-05 WO PCT/SE1998/001790 patent/WO1999018972A1/en active IP Right Grant
- 1998-10-05 JP JP2000515605A patent/JP2001519398A/ja active Pending
- 1998-11-18 SA SA98190775A patent/SA98190775A/ar unknown
Also Published As
Publication number | Publication date |
---|---|
ZA988886B (en) | 1999-04-12 |
JP2001519398A (ja) | 2001-10-23 |
EP1310259A2 (en) | 2003-05-14 |
EP1021194B1 (en) | 2003-05-14 |
WO1999018972A1 (en) | 1999-04-22 |
SE9703691D0 (sv) | 1997-10-10 |
DK1021194T3 (da) | 2003-09-01 |
ATE240107T1 (de) | 2003-05-15 |
DE69814656D1 (de) | 2003-06-18 |
US6372728B1 (en) | 2002-04-16 |
EP1310259A3 (en) | 2003-05-21 |
ES2200378T3 (es) | 2004-03-01 |
PT1021194E (pt) | 2003-09-30 |
AU9469198A (en) | 1999-05-03 |
EP1021194A1 (en) | 2000-07-26 |
SA98190775A (ar) | 2005-12-03 |
DE69814656T2 (de) | 2004-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |